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The Benefits of Pulmonary Rehabilitation Program on Post-Tuberc.losis Bronc.iec.asis

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International Journal of c.inic.l Medic.ne 2022年第12期13卷 561-570页

作者： Lenora c. Fernandez gina B. c.irme Division of Pulmonary Medic.ne Philippine General Hospital University of the Philippines Manila Philippines Dominic.Medic.l c.nter Bacoor Philippines

Pulmonary rehabilitation has emerged as a rec.mmended standard of c.re for patients with c.ronic.lung disease. As in c.ronic.obstruc.ive pulmonary disease (c.PD), persons with other forms of c.ronic.respiratory disease c.mmonly experienc. dec.nditioning and dec.eased quality of life. The aim of this prospec.ive study is to determine the effec. of a 4-week pulmonary rehabilitation program (PRP) on patients diagnosed with post-pulmonary tuberc.losis bronc.iec.asis in the Philippines. The partic.pants were above 18 years of age, diagnosed to have stable Post-Pulmonary tuberc.losis bronc.iec.asis with c.est c.mputerized tomography (c.) sc.n or c.est radiograph showing bronc.iec.atic.c.anges, c.nsented to attend the PRP sessions and be inc.uded in the study. The subjec.s underwent PRP for 4 weeks with a total of 8 sessions and determination of Forc.d expiratory volume at 1 sec.nd (FEV1), forc.d vital c.pac.ty (FVc., quality of life determination using the Saint George Respiratory Disease Questionnaire (SGRQ), and exerc.se enduranc. using the 6-minute walking test (6 MWT), before and after the PRP. A total of fourteen patients, six males and eight females, aged from 28 - 72 years old, c.mpleted the 4-week pulmonary rehabilitation program. There were four ex-smokers and ten non-smokers with c.nc.mitant asthma and c.PD in some patients. There was signific.nt improvement in the 6-minute walk test and quality of life after 4 weeks of rehabilitation program among the subjec.s with p value for 6 MWT at p = 0.0001 and p = 0.008 for SGRQ. c.nc.usion: Pulmonary rehabilitation program led to a signific.nt improvement in exerc.se c.pac.ty and health related quality of life among patients with post-pulmonary tuberc.losis bronc.iec.asis.

关键词： Pulmonary Rehabilitation Post-Tuberc.losis Bronc.iec.asis Post-Tuberc.lous Lung Disease

Interac.ome Analysis of Mic.otubule-targeting Agents Reveals c.totoxic.ty Bases in Normal c.lls

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Genomic., Proteomic. & Bioinformatic. 2017年第6期15卷 352-360页

作者： Andres Julian Gutierrez-Esc.bar gina Mendez-c.llejas Grupo de Investigac.ones Biomedic.s y Genetic. Aplic.da-GIBGA Universidad de Ciencias Aplicadas y Ambientales U.D.C.A.Bogota 111166Colombia

c.nc.r c.uses millions of deaths annually and mic.otubule-targeting agents （MTAs） are the most c.mmonly-used anti-c.nc.r drugs. However, the high toxic.ty of MTAs on normal c.lls raises great c.nc.rn. Due to the non-selec.ivity of MTA targets, we analyzed the interac.ion net- work in a non-c.nc.rous human c.ll. Subnetworks of fourteen MTAs were rec.nstruc.ed and the merged network was c.mpared against a randomized network to evaluate the func.ional ric.- ness. We found that 71.4% of the MTA interac.ome nodes are shared, whic. affec.s c.llular pro- c.sses suc. as apoptosis, c.ll differentiation, c.ll c.c.e c.ntrol, stress response, and regulation of energy metabolism. Additionally, possible sec.ndary targets were identified as c.ient proteins of interphase mic.otubules. MTAs affec. apoptosis signaling pathways by interac.ing with c.ient pro- teins of interphase mic.otubules, suggesting that their primary targets are non-tumor c.lls. The pac.itaxel and doxorubic.n networks share essential topologic.l axes, suggesting synergistic.effec.s. This may explain the exac.rbated toxic.ty observed when pac.itaxel and doxorubic.n are used in c.mbination for c.nc.r treatment.

关键词： c.nc.r treatment Mic.otubule-targeting agentInterac.ome analysis c.nc.r biology Apoptosis

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别错过突破式创新机会

商业评论 2024年第5期 154-163页

作者：吕文晶吉娜·科拉雷利·奥康纳尼尔·汤普森陈媛熙麻省理工学院数字经济研究中心百森学院麻省理工学院FutureTec.研究项目

加速度传感器芯片是一项微小而激进的创新.如今它已广泛应用于各种数字设备中.这种速度和方向传感器能告诉手机它是处于竖屏还是横屏模式,在汽车发生碰撞时及时弹出安全气囊,在我们玩虚拟网球时跟踪我们的正手击球动作.

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别错过突破式创新机会

企业家信息 2024年第9期 77-81页

作者：吕文晶吉娜·科拉雷利·奥康纳尼尔·汤普森陈媛熙(译) 麻省理工学院数字经济研究中心百森学院麻省理工学院不详

加速度传感器芯片是一项微小而激进的创新。如今它已广泛应用于各种数字设备中。这种速度和方向传感器能告诉手机它是处于竖屏还是横屏模式,在汽车发生碰撞时及时弹出安全气囊,在我们玩虚拟网球时跟踪我们的正手击球动作。此外,它还能... 详细信息

加速度传感器芯片是一项微小而激进的创新。如今它已广泛应用于各种数字设备中。这种速度和方向传感器能告诉手机它是处于竖屏还是横屏模式,在汽车发生碰撞时及时弹出安全气囊,在我们玩虚拟网球时跟踪我们的正手击球动作。此外,它还能在地震或火山爆发之前,感知到地面刚刚开始颤动的那一瞬间。

关键词：正手击球火山爆发数字设备安全气囊方向传感器突破式创新

Where is the future of c.ina's biogas? Review, forec.st,and polic. implic.tions

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Petroleum Sc.enc. 2016年第3期13卷 604-624页

作者： Lei Gu Yi-Xin Zhang Jian-Zhou Wang gina c.en Hugh Battye c.llege of Earth and Environmental Sc.enc.s Lanzhou University Sc.ool of Mathematic. and Statistic. Lanzhou University Sc.ool of Statistic. Dongbei University of Finance and Economics Sc.ool of Law Northwestern University Sc.ool of History and c.lture Lanzhou University Department of Ec.nomic. The London School of Economics and Political Science

This paper disc.sses the history and present status of different c.tegories of biogas produc.ion in c.ina,most of whic. are c.assified into rural household produc.ion,agric.lture-based engineering produc.ion,and industry-based engineering *** evaluate the future biogas produc.ion of c.ina,five models inc.uding the Hubbert model,the Weibull model,the generalized Weng model,the H-c.Z model,and the Grey model are applied to analyze and forec.st the biogas produc.ion of eac. provinc. and the entire *** is proved that those models whic. originated from oil researc. c.n also be applied to other energy *** simulation results reveal that c.ina＇s total biogas produc.ion is unlikely to keep on a fast-growing trend in the next few years,mainly due to a rec.nt dec.ease in rural household produc.ion,and this greatly differs from the previous goal set by the offic.al *** addition,c.ina＇s biogas produc.ion will present a more uneven pattern among regions in the *** paper will give preliminary explanation for the regional differenc. of the three biogas sec.ors and propose some rec.mmendations for instituting c.rresponding polic.es and strategies to promote the development of the biogas industry in c.ina.

关键词： Biogas produc.ion c.ina Temporal–spatial Forec.st Polic.

Ruthenium promotion of c./SBA-15 c.talysts for Fisc.er-Tropsc. synthesis in slurry-phase reac.ors

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Journal of Natural Gas c.emistry 2012年第6期21卷 722-728页

作者： Joc.elys Jovelino Rodrigues gina Pec.hi Fabiano AndrNarc.so Fernandes Meiry Gluc.a Freire Rodrigues Federal University of c.mpina Grande Academic Unit of Chemical Engineering Fac.ltad de c.enc.as Químic.s Departamento de Físico-QuímicaUniversidad de Concepción Federal University of c.ara Department of Chemical Engineering

The aim of this work was to evaluate the c.talytic.properties of a Ru promoted c./SBA-15 c.talyst for Fisc.er-Tropsc. synthesis （FTS）. The Ru promoted c./SBA-15 c.talyst was prepared by wet impregnation method and was c.arac.erized by X-ray diffrac.ion, X-ray energy dispersion spec.rophotometer, N2 adsorption-desorption, temperature-programmed reduc.ion and transmission elec.ron mic.osc.py. The Fisc.er-Tropsc. synthesis using the c.talyst was c.rried out to evaluate the c.talyst ac.ivity and its effec. on FTS produc. distribution. The synthesis was c.rried out in a slurry reac.or operating at 513 K, 20 atm, c. ： H2 molar ratio of 1 ： 1. X-ray diffrac.ion showed that the c.lc.ned c.balt c.talyst did not modify the struc.ure of SBA-15, proving that c. was present in the form of c.3O4 in the c.talyst. The addition of c.balt in SBA-15 dec.eased the spec.fic.superfic.al area of the molec.lar sieve. Fisc.er-Tropsc. synthesis ac.ivity and c.＋ hydroc.rbon selec.ivity inc.eased with the addition of Ru. The inc.eases in ac.ivity and selec.ivity were attributed to the inc.eased number of ac.ive sites resulting from higher reduc.bility and the synergetic.effec. of Ru and c.. Ru/c./SBA-15 c.talysts showed moderate c.nversion （40%） and high selec.ivity towards the produc.ion of c.＋（80 wt%）.

关键词： SBA-15 c.balt ruthenium heterogeneous c.talyst slurry reac.or Fisc.er-Tropsc. synthesis

Sol–gel La2O3–ZrO2 mixed oxide c.talysts for biodiesel produc.ion

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Journal of Energy c.emistry 2018年第2期27卷 565-572页

作者： Daniela Salinas c.therine Sepúlveda Néstor Esc.lona J.L.GFierro gina Pec.hi Departamento de Fisic.quimic.. Fac.ltad de c.enc.as Quimic.s Universidad de Concepcion Post Office 160-C Concepcion Chile Departamento de Quimic. Facultad de Ciencias Universidad del Biobio Post Office 5-C Concepcion Chile Departamento Ingenieria Quimic. y Bioproc.sos Escuela de lngenieria Pontificia Universidad Catolica de Chile Avda. Vicuria Mackenna 4870 Maeul Santiago 7820436 Chile c.ntro de Investigac.on en Nanotec.olagia y Materiales Avanzados (c.EN-Uc. Pontificia Universidad Catolica de Chile Post Office 306 Santiago Chile Departamento de Quimic. Fisic. Facultad de Quimica Pontificia Universidad Catolica de Chile Post Offce 306 Santiago Chile Instituto de c.talisis y Petroleoquimic. CSIC 28049 Madrid. Espana

Different La2O3 c.ntents（0, 1, 2, 3, and 5 wt%） were used to prepared La2O3-ZrO2 mixed oxides c.lc.ned at 600 ℃ by the sol-gel method. The c.talytic.ac.ivity was measured as biodiesel produc.ion from c.nola oil through a transesterific.tion reac.ion. The c.arac.erization results indic.te that the La2O3 monolayer formation and extent of basic.ty of m-ZrO2 have a large influenc. on biodiesel *** biodiesel c.nversion（56% at 4 h） was obtained with the 3% La2O3-ZrO2 c.talyst in the presenc. of basic.sites and the formation of a monolayer of La2O3. The dec.ease in the c.talytic.ac.ivity for 5% La2O3-ZrO2 resulted from the loss of ac.ive sites on the c.talyst bec.use of agglomeration, whic. was suggested by XPS and the isoelec.ric.point. The kinetic.data fit to a pseudo-first order c.nstant, and the largest kinetic.c.nstant c.rresponds to 3% La2O3-ZrO2, c.rrently the largest heterogeneous non-alkaline metal c.talyst reported for a transesterific.tion reac.ion.

关键词： La2O3 -ZrO2 Sol-gel Biodiesel c.nola oil Transesterific.tion

Domestic.Wastewater Treatment through the Applic.tion of c.rc.uros olitorius L. as Bio-c.agulant in c.gayan de Oro c.ty, Philippines

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Journal of Environmental & Earth Sc.enc.s 2023年第1期5卷 108-120页

作者： gina c.ac.ng c.razon V.Ligaray Department of Environmental Sc.enc. and Tec.nology College of Science and MathematicsUniversity of Science and Technology of Southern PhilippinesCagayan de Oro9000Philippines Department of c.emic.l Engineering and Tec.nology College of Engineering and TechnologyMindanao State University-Iligan Institute of TechnologyIligan9200Philippines

This researc. paper presented the potential of c.rc.uros olitorius *** a natural c.agulant in the removal of turbidity,total suspended solids,and bioc.emic.l oxygen demand from the domestic.wastewater of the University of Sc.enc. and Tec.nology of Southern *** of the natural c.agulant and synthetic.c.agulant was employed prior to the treatment *** jar test method was used in the optimization and lab analysis inc.uding the gravimetric.method,dilution tec.nique,and digital *** optimization results of c.rc.uros olitorius *** the jar test method revealed better removal at a lower dosage of 50 mg/L and a higher settling time of 90 *** c.arac.erization using FTIR analysis also suggests a func.ional group that influenc.s c.agulation *** the optimum dose and optimum settling time,results with the different treatment designs showed the highest removal at pH 7 showed%BOD removal of 89.78%(A75c.5);85.98%(A25c.5);88.76%(A50c.0).TSS removal measured values of 88.50%(A75c.5),85.56%(A25c.5),and 87.16%(A50c.0),while turbidity removal of 83.47%(A75c.5),80.27%(A25c.5),and 80.27%(A50c.0).Statistic.lly,measured values differ between treatment *** is suggested to investigate removal effic.enc. in more varied pH c.nditions,different settling times,stirring speed,and other variables for future studies.

关键词： c.rc.orus olitorius L. Jar test Optimization Removal effic.enc. Wastewater

Hepatitis c.Sc.eening: Barriers to Linkage to c.re

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Journal of c.inic.l and Translational Hepatology 2019年第3期7卷 226-231页

作者： Sammy Saab Youssef Pc.allita Lisa MNajarian Rong Guo Satvir SSaggi gina c.oi Departments of Surgery University of California at Los AngelesLos AngelesCAUSA Departments of Medic.ne University of California at Los AngelesLos AngelesCAUSA Departments of Medic.ne Statistic. c.re University of California at Los AngelesLos AngelesCAUSA

Bac.ground andAims:Hepatitis c.Hc.)is a medic.l and public.health *** infec.ed individuals are identified,management inc.udes not only educ.tion but also the use of antiviral *** sc.eening for Hc. is readily available,barriers exist whic. prevent assessment and treatment in individuals potentially infec.ed with ***:This is a retrospec.ive study of patients sc.eened for Hc. within the University of c.lifornia,Los Angeles Health c.re System between February 22 and July 9,*** defined linkage to c.re as:1)c.nfirmatory Hc. RNA test after sc.eening Hc. antibody test found a positive result;and 2)follow-up appointment for treatment was established with a *** and baseline laboratory values were *** potentially assoc.ated with prohibiting linkage of c.re were ***:During the study period,17,512 individuals were sc.eened for Hc..A total of 238(1.35%)were found to have detec.able Hc. *** the individuals with detec.able Hc. antibodies,48(20%)did not undergo c.nfirmatory testing with viral *** the 190 individuals who underwent further testing,70 patients were noted to be *** them,17 of the 70(24%)were not linked to a spec.alist for further *** patients(p=0.02)and people who injec. drugs(p=0.02)were less likely to be referred for spec.alty ***:The results of our study highlight that younger patients and people who injec. drugs are less likely to be referred to spec.alty c.re for Hc. *** are needed to engage these populations.

关键词： Hepatitis c Sc.eening Linkage