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Open Journal of Epidemiology 2016年第3期6卷 167-172页

作者： Shafquat Rozi Sadia Mahmud gillian Lancaster Nida Zahid Department of Mathematics and Statistics Lancaster University Lancashire UK Department of Community Health Sciences Aga Khan University Karachi Pakistan Department of Paediatrics & Child Health Aga Khan University Karachi Pakistan

Introduction: Among young teens, about one.in five smokes worldwide. Adolescents spend a considerable amount of their time in school, and the school environment is therefore important for child health practices and outcomes. Objectives: We aimed to investigate the impact on smoking behavior of the school environment and the personal characteristics of male teenage students attending schools in Pakistan, taking into account the survey sampling structure. Methods: A two-stage cluster sampling with stratification was employed, and we interviewed 772 male secondary school students. We adopted random effect and gene.alizing estimating equation models. Results: Peer pressure in particular had a strong influence on adolescents smoking;those whose friends smoked were up to 6 times more likely to smoke. Family smoking was also significantly associated with adolescents smoking, but those students whose mother was educated were 50% less likely to smoke. The fitted random effect model indicated that the between school variability was significant (p-value < 0.01), indicating differences in smoking habits between schools. A random coefficient model showed that variability among schools was not significantly different for public and private schools. Conclusion: Public health campaigns for smoking cessation should target not only the individual but also the families of adolescents attending schools.

关键词： Teenage Smoking Multilevel Model Binary Outcome Public & Private Schools

Open-Label Real-World Pharmacy Purchaser Study of Two Fixed-Dose Combination OTC Cold Treatments;Wick MediNait, Wick DayMed Capsules or a Combination of Both

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Open Journal of Respiratory Diseases 2018年第3期8卷 43-62页

作者： gillian Phillipson David Ramsey Sue Aspley Ingo Fietze Procter&Gamble International Operations Geneva Business CenterGenevaSwitzerland Procter&Gamble Health Care MasonOHUSA Procter&Gamble Technical Centres Ltd. SurreyUK Center of Sleep Medicine Charité—Universitatsmedizin BerlinBerlinGermany

Acute upper respiratory tract infections, i.e. common colds cause multiple symptoms and affect adults on average 2 - 4 times a year and children 6 - 8 times per year. Thousands of non-prescription, over-the-counter products are used by sufferers, aimed at relieving the various both er some symptoms such as cough, nasal congestion, sore throat, etc. This study evaluated real-world effectivene.s of Wick MediNait or Wick DayMed medicine. alone.and together in a combination as a day and night treatment regimen. Adult cold sufferers were recruited in pharmacy by pharmacy staff following self-purchase of either Wick MediNait, Wick DayMed capsules, or the combination of DayMed and MediNait. Participants completed online.questionnaires before and after product use (evening of the first day for DayMed and the morning after using MediNait at bedtime). For the primary endpoint “Wick MediNait was effective at relieving my symptoms”, there was a statistically significant difference (p ne.ther Agreed or Disagreed, Disagreed or Strongly Disagreed. Further, all symptoms evaluated (cough, runny nose, nasal congestion, fever, headache, sore throat, muscle aches and pains, sne.zing) were statistically improved after MediNait and DayMed alone.and when both were used, and users were satisfied with both treatments. All treatments were well tolerated with minimal adverse event reporting. The diurnal use of DayMed capsules combine. with the nocturnal use of MediNait allows cold sufferers to efficiently self-manage their symptom relief throughout the day and night.

关键词： Wick MediNait Real-World Use User Satisfaction Observational Cold Symptom Relief Sleep Quality

微芯片电泳与电感耦合等离子体质谱的连接技术研究

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高等学校化学学报 2004年第Z1期25卷 109-110页

作者：宋启军 gillian M.Greenway Tom McCreedy 江南大学化学与材料工程学院无锡214036 英国赫尔大学化学系英国赫尔大学化学系

研究了基于微芯片电泳分离和电感耦合等离子体质谱的连接技术,并对不同形态的Cu和As进行了快速分离和检测.

关键词：微芯片电泳电感耦合等离子体质谱(ICP-MS) 检测

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克服羞怯

Computed tomography overestimation of esophageal tumor length: Implications for radiotherapy planning

丛书名：新向导丛书.大众心理系列

2001年

作者：（英）gillian Butler 周晓林等译

本书针对特定的问题制定出特定的认知行为治疗的原则和方法，提供了系统的治疗方案，并建议每一个心理障碍患者使用它去克服其所受到的困扰。

ISBN: (纸本)750193231X

本书针对特定的问题制定出特定的认知行为治疗的原则和方法，提供了系统的治疗方案，并建议每一个心理障碍患者使用它去克服其所受到的困扰。

关键词：精神疗法

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World Journal of Gastrointestinal Oncology 2010年第4期2卷 197-204页

作者： Karim Sillah Luke R Williams Hans-Ulrich Laasch Azeem Saleem gillian Watkins Susan A Pritchard Patricia M Price Catharine.M West Ian M Welch Department of Gastrointestinal Surgery University Hospital of South Manchester NHS Foundation TrustSouthmoor RoadManchester M23 9LTUnited Kingdom School of Cancer&Enabling Sciences University of ManchesterChristie HospitalWilmslow RoadManchester M20 4BXUnited Kingdom Department of Radiology University Hospital of South Manchester NHS Foundation TrustSouthmoor RoadManchester M23 9LTUnited Kingdom Department of Radiology The Christie NHS Foundation TrustWilmslow RoadManchester M20 4BXUnited Kingdom Department of Histopathology University Hospital of South Manchester NHS Foundation TrustSouthmoor RoadManchester M23 9LTUnited Kingdom

AIM:To assess the relationship between preoperative computed tomography(CT)and postoperative pathological measurements of esophageal tumor length and the prognostic significance of CT tumor length ***:A retrospective study was carried out in 56 patients who underwent curative *** lengths were measured on the immediate preoperative CT and on the post-operative resection ***-and intra-observer variations in CT measurements were *** data were ***:There was a weak correlation between CT and pathological tumor length(r=0.30,P=0.025).CT lengths were longer than pathological lengths in 68%(38/56)of patients with a mean difference of 1.67 cm(95%CI:1.18-2.97).The mean difference in measurements by two radiologists was 0.39 cm(95% CI:-0.59-1.44).The mean difference between repeat CT measured tumor length(intra-observer variation) were 0.04 cm(95%CI:-0.59-0.66)and 0.47 cm (95%CI:-0.53-1.47).When stratified,patients not receiving ne.adjuvant chemotherapy showed a strong correlation between CT and pathological tumor length(r =0.69,P=0.0014,n=37)than patients that did(r= 0.13,P=0.43,n=19).Median survival with CT tumor length>5.6 cm was poorer than with smaller tumors,but the difference was not statistically ***:Esophageal tumor length assessed using CT does not reflect pathological tumor extent and should not be the only modality used for management decisions,particularly for planning radiotherapy.

关键词： Computed tomography Esophageal cancer Radiotherapy

Observational Study of a Multi-Active Ingredient Over-the-Counter Cold Remedy Following Active Pharmacist Recommendation

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Open Journal of Respiratory Diseases 2017年第1期7卷 41-52页

作者： gillian Lisa Phillipson John David Hull Boleslaw Samoliński Procter&Gamble Greater London Innovation CentreSurreyUK Department of the Prevention of Environmental Hazards and Allergology Faculty of Health SciencesMedical University of WarsawWarsawPoland

Real-world user satisfaction with a fixed dose combination over-the-counter cold remedy (Vicks Symptomed Complete Cytrynowy hot drink;VSCC) was evaluated in a prospective, non-comparative, observational study involving 176 pharmacies in Poland from February to April 2015. 1391 participants completed a questionnaire in the pharmacy and several paper questionnaires at home following use of the product at their own discretion. Participants returne. their completed questionnaires to the pharmacy. 1356 participants were included in the intent-to-treat analysis. Participants highly valued the advice from their pharmacist (97%, P < 0.0001, important vs. not important) and thought the quality of that advice was good (93%, P < 0.0001, good/very good vs. very bad-fair). 96% of participants found VSCC to be effective in some way against their cold symptoms (P < 0.0001, effective vs. not effective) and 68% of them stated that it was better than any other cold therapy they had used before (P < 0.0001, better/best vs. same/worse). Adverse event reporting was very low.

关键词： Common Cold Upper Respiratory Tract Infection Observational Pharmacy Over-the-Counter Fixed-Dose Combination Common Cold Symptoms

Handbook of clinical laboratory testing during pregnancy 1

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Incidental meandering right pulmonary vein,literature review and proposed nomenclature revision

丛书名： Current Clinical Pathology

2004年

作者： Ann M. Gronowski foreword by gillian Lockitch.

ISBN: (纸本)9781588292704

Practicing specialists in pathology, laboratory medicine. and obstetrics comprehensively summarize the latest scientific findings and their experiences in the use and interpretation of laboratory testing in patients who are pregnant or experiencing recurrent pregnancy loss. Topics of interest include the effects of normal physiological changes on test results, test selection for diagnosis, changes in reference ranges, monitoring the pregnant patient, ne. technologies, and the limitations of laboratory testing. The authors not only clearly explain currently used test methods and technologies for the nontechnical reader, but also provide comprehensive details for laboratory professionals. The comprehensive appendix that compiles published normal reference ranges by first, second, and third trimester consttitutes an excellent resource for professionals caring for pregnant women

关键词： Prenatal Diagnosis

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World Journal of Radiology 2013年第5期5卷 215-219页

作者： Mark Alexander Rodrigues gillian Ritchie John Tallach Murchison Department of Radiology Royal Infirmary of EdinburghEdinburghScotland EH16 4SAUnited Kingdom

We report a case of an anomalous pulmonary vein on chest X-ray resembling a scimitar sign in an 80-year-old female undergoing investigation of *** computed tomography(CT) with multiplanar reformatting and maximum intensity projections demonstrated an aberrant right inferior pulmonary vein coursing inferomedially towards the diaphragm before turning superiorly and draining normally into the left *** diagnosis of an incidental meandering right pulmonary vein was *** case is used to review the literature on this rare pulmonary anomaly,including pathogene.is,its relationship with scimitar syndrome and scimitar variant,and diagnosis,with an emphasis on the role modern CT techniques can play in noninvasive diagnosis.A revision to the nomenclature of pulmonary vascular anomalies is proposed to help reduce confusion in the literature.

关键词： Incidental findings Pulmonary veins/abnor-malities Scimitar syndrome/radiography Tomography X-ray computed

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地幔柱:为什么现在怀疑?

科学通报 2005年第17期50卷 1814-1819页

作者： gillian R. Foulger 张宏福(翻译) 牛耀龄(校) Department of Earth Sciences Durham University Durham DH1 3LE UK. 不详

对地幔柱假说的重新评价也许是当今地球科学争论最激烈的问题.尽管如此,需要对地幔柱假说进行重新评价的根本原因对大部分学者而言并非十分清楚.主要原因可归结为:(1)许多观察与地幔柱最初模型的预测结果不符,(2)地幔中产生热地幔柱所... 详细信息

对地幔柱假说的重新评价也许是当今地球科学争论最激烈的问题.尽管如此,需要对地幔柱假说进行重新评价的根本原因对大部分学者而言并非十分清楚.主要原因可归结为:(1)许多观察与地幔柱最初模型的预测结果不符,(2)地幔中产生热地幔柱所需要的那种对流可能并不存在,(3)很多最初模型的衍生体被用来容纳相互矛盾的资料,以致于地幔柱假说实际上根本无法检验,以及(4)其他行之有效的模型均被长期忽视.不管最终结果如何,现在的激烈争论都应受欢迎,因为争论有助于新的发现,而不质疑地接受传统地幔柱模型则有碍于新发现.

关键词：地幔柱火山活动热点对流地幔板块构造热地幔柱怀疑重新评价柱模型

Heparin resistance in severe thermal injury:a prospective cohort study

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Burns & Trauma 2021年第1期9卷 157-169页

作者： Liam D Cato Benjamin Bailiff Joshua Price Christos Ermogene.us Jon Hazeldine.William Lester gillian Lowe Christopher Wearn Jonathan RB Bishop Jane. M Lord Naiem Moiemen Paul Harrison Scar Free Foundation Birmingham Centre for Burns Research University Hospitals Birmingham Foundation TrustQueen Elizabeth Hospital BirminghamMindelsohn WayBirminghamB152WBUK Department of Haematology University Hospitals Birmingham Foundation TrustMindelsohnWayBirminghamB152WBUK Institute of Inflammation and Ageing University of BirminghamBirminghamB152TTUK NIHR Surgical Reconstruction and Microbiology Research Centre University Hospitals Birmingham Foundation TrustMindelsohn WayBirminghamB152WBUK

Background:Low molecular-weight heparin(LMWH)is routine.y administered to burn patients for *** studies have reported heparin resistance,yet the mechanism(s)and prevalence have not been systematically *** hypothesized that nucleosomes,composed of histone.structures with associated DNA released from injured tissue and activated immune.cells in the form of ne.trophil extracellular traps(ne.s or ne.osis),ne.tralize LMWH resulting in suboptimal anticoagulation,assessed by reduction in anti-factor Xa ***:Blood was sampled from>15%total body surface area(TBSA)burn patients receiving LMWH on days 5,10 and *** anti-factor Xa(AFXa)activity,anti-thrombin(ATIII)activity,cellfree DNA(cfDNA)levels and nucleosome levels were *** effects regression was adjusted for multiple confounders,including injury severity and ATIII activity,and was used to test the association between nucleosomes and ***:A total of 30 patients with severe burns were *** TBSA 43%(SD 17).Twentythree(77%)patients were affected by heparin resistance(define. by AFXa activityne.atively correlated with AFXa(r=−0.29,p=0.050)consistent with the *** final model,with peak AFXa as the response variable,was adjusted for nucleosome levels(p=0.0453),ATIII activity(p=0.0053),LMWH dose pre-sample(p=0.0049),drug given(enoxaparin or tinzaparin)(p=0.03),and other confounders including severity of injury,age,gender,time point of ***:Heparin resistance is a prevalent issue in severe *** levels were increased post-burn,and showed an inverse association with AFXa consistent with the hypothesis that they ma

关键词： Burn Heparin resistance Low molecular-weight heparin Nucleosomes ne.trophil extracellular traps Factor-Xa Thrombosis Enoxaparin ne.osis