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Design of the New San Francisco-Oakland Bay Bridge Self-Anchored Suspension Bridge

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Design of the New San Francisco-Oakland Bay Bridge Self-Anch...

The Janus of mIS in hepatobiliary surgery:Importance of maximally invasive surgery in an era of minimally invasive surgery

国际桥梁2004年大会

作者： Marwan NADER Rafael MANZANAREZ george baker Principal T.Y. Lin International San Francisco CA USA Vice President T.Y. Lin International San Francisco CA USA Chief Engineer Roman Wolchuk Engineers Jersey City NJ USA

＜正＞ The Self-Anchored Suspension Bridge was selected out of four other competing design as the signature span for the new San Francisco-Oakland Bay Bridge which will replace the seismically vulnerable East Spans of... 详细信息

关键词： Suspension Bridge Seismic Design Steel Bridges.

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Hepatobiliary & Pancreatic Diseases International 2020年第5期19卷 409-410页

作者： Maria R.Baimas-george Christoph Tschuor John B.Martinie David A.Iannitti Erin H.baker Dionisios Vrochides Division of HPB Surgery Department of SurgeryAtrium Health-Carolinas Medical Center1025 Morehead Medical DriveSuite 600CharlotteNC 28204USA

As surgeons formidably continue to forge into the twentytwenties,after a considerably coronavirus-induced rocky start,one can predict that the era of minimally invasive surgery(mIS),an era of robotics,telehealth,and enhanced recovery after surgery(ERAS■),is not only here to stay but will continue to thrive,develop,and transform our *** of robotics platforms would be hard pressed not to indulge in this *** the satisfyingly large midline“stem to stern”,the impressing exposuregenerating Makuuchi or transverse abdominal,the Kocher,paramedian,McBurney,Chevron,and Pfannenstiel incisions begin to disappear and fade away into a scar minimizing future precluding trauma laparotomies?Most likely *** and developing the skill and technique for a minimally invasive“mIS”approach does not negate or abrogate the maximally invasive“MIS”*** is not one or the other;not a“to be or not to be”Shakespearean *** surgery is a qualified landscape upon which to illuminate and exemplify this declaration:the necessity and companionship of“mIS”and“MIS”–minimally and maximally invasive surgery.

关键词： surgery maximal continue

Prognostic impact of the Bismuth-Corlette classification:Higher rates of local unresectability in stageⅢb hilar cholangiocarcinoma

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Hepatobiliary & Pancreatic Diseases International 2020年第2期19卷 157-162页

作者： Michael J Passeri Maria R Baimas-george Jesse K Sulzer David A Iannitti John B Martinie Erin H baker Lee M Ocuin Dionisios Vrochides Division of HPB Surgery Department of SurgeryCarolinas Medical Center1025 Morehead Medical Dr.Suite 600CharlotteNC 28204USA

Background:The Bismuth-Corlette(BC)classification is used to categorize hilar cholangiocarcinoma by proximal extension along the biliary *** the right hepatic artery crosses just behind the left bile duct,we hypothesized that BCⅢb tumors would have a higher likelihood of local unresectability due to involvement of the contralateral ***:A retrospective review of a prospectively maintained database identified patients with hilar cholangiocarcinoma taken to the operating room for intended curative resection between April 2008 and September *** were assigned BC stages based on preoperative ***:Sixty-eight patients were included in the *** underwent staging laparoscopy after which 16 cases were aborted for metastatic *** the remaining 52 cases,14 cases were explored and aborted for locally advanced ***-eight underwent attempt at curative *** exclud-ing cases aborted for metastatic disease,the chance of proceeding with resection was 55.6%for BCⅢb staged lesions compared to 80.0%of BCⅢa lesions and to 82.4%for BCⅠ-Ⅲa staged lesions(P<0.05).About 44.4%of BCⅢb lesions were aborted for locally advanced disease versus 17.6%of remaining BC ***:When hilar cholangiocarcinoma is preoperatively staged as BCⅢb,surgeons should antici-pate higher rates of locally unresectable disease,likely involving the right hepatic artery.

关键词： Bismuth-Corlette stage Cholangiocarcinoma Biliary tract surgical procedures Biliary tree Liver surgery

Hematopoietic Stem and Progenitor Cell(HSPC)Mobilization Responses to Different Exercise Intensities in Young and Older Adults

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Journal of Science in Sport and Exercise 2020年第1期2卷 47-58页

作者： Joshua P.Nederveen Jeff baker george Ibrahim Victoria Ivankovic Michael E.Perciva Gianni Parise Department of Kinesiology McMaster UniversityHamiltonON L8S 4L8Canada Child and Youth Mental Health Program McMaster University Medical CentreHamiltonON L8N 3Z5Canada

Introduction Hematopoietic stem and progenitor cells(HSPC)are responsible for the reconstitution of blood cells and thought to contribute to peripheral tissue *** acute exercise in young adults,HSPC are mobilized from their niche in bone marrow into circulation,however the kinetics of mobilization following exercise is not well understood in older *** the present study,we aimed to investigate how exercise intensity influences mobilization of specific subpopulations of HSPC,and how mobilization is affected by *** Healthy older men(OM;69.9±2.0 years)and young men(YM;21.5±0.8 years)performed three separate bouts of exercise on a cycle ergometer:70%of their peak work rate(WRpeak)until volitional fatigue,30%of their WRpeak work matched to the 70%WRpeak trial,and a high intensity interval training(HIIT)*** samples were collected before,immediately post,and 10,30,and 60 min *** blood cells,hematocrit,and mononuclear cells isolated by density gradient centrifugation were quantified using flow *** Mononuclear cells,CD34+,CD34+/CD38+,CD34+/CD110+,CD3+/CD(16+56)+,CD11c+/CD123-,and CD11c-/CD123+cells per millilitre of blood increased immediately post-exercise,but predominately in the 70%WRpeak trial in both OM and *** Taken together,our evidence suggests that higher intensity exercise but also volume is necessary for the mobili-zation of ***,the pattern of mobilization was nearly identical in OM as compared to YM though to a lesser extent than their younger counterparts.

关键词： Exercise Hematopoietic stem cells Pmgenitor cells Aging F1ow cytometry

Comparative sensitivity to environmental variation and human disturbance of Asian tapirs (Tapirus indicus) and other wild ungulates in Thailand

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Integrative Zoology 2012年第4期7卷 389-399页

作者： Antony J.LYNAM Naruemon TANTIPISANUH Wanlop CHUTIPONG Dusit NGOPRASERT Megan C.baker Passanan CUTTER george GALE Shumpei KITAMURA Robert STEINMETZ Ronglarp SUKMASUANG Somying THUNHIKORN Global Conservation Program Wildlife Conservation Society(WCS)BronxNYUSA IUCN/SSC Tapir Specialist Group BangkokThailand Conservation Ecology Program King Mongkut’s University of Technology ThonburiBangkokThailand Center for Species Survival Smithsonian Conservation Biology InstituteFront RoyalVirginiaUSA Conservation Biology Program University of MinnesotaSt.PaulMinnesotaUSA Museum of Nature and Human Activities SandaJapan WWF Thailand BangkokThailand Department of Forest Biology Kasetsart UniversityBangkokThailand Wildlife Research Division Department of National ParksWildlife and Plants ConservationBangkokThailand

Southeast Asia’s tropical forests suffer the highest rates of deforestation and disturbance of any on Earth,with poorly understood impacts on native *** tapirs(Tapirus indicus)are among the least studied of the large mammals in these *** records from 9 camera trap surveys in 7 of the largest(>1000 km2)pro-tected area complexes,we assessed the influence of environmental variation and human-induced disturbance on tapir *** were detected at 13%of locations sampled,significantly associated with evergreen for-est(P40%over the past 20 *** recommend surveys to fill gaps in the understanding of the status in lesser-known protected areas,research to better understand the fine-scale environmental influences on behavior and habitats of tapirs,and other forest un-gulates,and continued legal status for tapirs in the highest category of protection.

关键词： Asian tapir camera traps conservation logistic regression ungulates

Volunteering and Depression among Older Adults: An Empirical Analysis Based on CLASS 2018

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International Journal of Mental Health Promotion 2023年第3期25卷 403-419页

作者： Zhendong Wu Chen Xu Liyan Zhang Yang Wang george W.Leeson Gong Chen Julien S.baker Xiao-Guang Yue School of Law Humanities and SociologyWuhan University of TechnologyWuhan430070China Beijing Institute of Aerospace Information Defense Technology Academy of CASICBeijing100013China The People’s Government of Niulanshan Town Beijing101301China Institute of Population Research Peking UniversityBeijing100091China Oxford Institute of Population Ageing OxfordOX26PRUK Department of Sport Physical Education and HealthHong Kong Baptist UniversityHong Kong999077China Department of Computer Science and Engineering European University CyprusNicosia1516Cyprus CIICESI-ESTG Politécnico do PortoFelgueiras4610-156Portugal

Introduction:Older adults are prone to high levels of depression due to their deteriorating physical functions and shrinking social networks after *** as an important social activity is essential for alleviating depression by building social *** paper aims to examine the effect of volunteering on depression among older adults by using China Longitudinal Aging Social Survey(CLASS 2018)***:This study uses descriptive analysis and chi-square tests to show differences in demographic factors of older adults’volun-teerism participation,followed by bivariate correlation analysis to examine the correlation between the vital ***,stratified linear regression analysis is used to research the significant level and impact between volunteering and degree of expertise,frequency,and variety of ***:8,459 older adults are included in *** research reveals that older adults who are younger,live in urban areas,are married,or have a higher degree of education tend to have fewer depressive ***,participation in volun-teering(OR=0.90,95%CI:0.8,1.1,p<0.001),as well as that demands specialized skills(OR=0.51,95%CI:0.30,0.2,p<0.001),more frequency of participation(OR=1.85,95%CI:1.53,2.18,p<0.001),and a wider variety of activities(OR=0.21,95%CI:0.12,0.29,p<0.001),all have a positive inﬂuence on depression ***/Conclusion:Older adults who participate in voluntary services have lower depression symptoms and should be encouraged to use their professional skills and increase participation frequency and variety in this *** article suggests that governments should help older adults participate in voluntary services by time bank which will further strengthen social ties,rebuild social networks and alleviate depression symptoms of older adults.

关键词： Volunteering depression mental health older adults China time banking

Practical cardiology an approach to the management of problems in cardiology 2nd ed

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Intravenous haloperidol for the treatment of intractable vomiting,cyclical vomiting,and gastroparesis

2008年

作者： Simon O'Connor george Nikoli Tracey baker

来源：畅想之星图书光盘版（南... 评论

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World Journal of Emergency Medicine 2021年第3期12卷 228-231页

作者： Brad E.Schwartz Karen Keller baker Andrew J.Bleinberger Amina Lleshi Raul Cruz-Cano Department of Emergency Medicine University of Maryland Capital Region HealthUM Prince George’s Hospital CenterCheverly 20785USA Ross University School of Medicine Bridgetown Bridgetown 11093Barbados Department of Epidemiology and Biostatistics School of Public Health of the University of MarylandBaltimore 21201USA

Dear editor,The incidence of emergency department(ED)visits from gastroparesis and cannabinoid hyperemesis syndrome has increased by two folds over the past decade.[1-3]Roldan et al[4]reported that patients with these conditions often have prolonged ED stays and are likely to be hospitalized because of the danger of dehydration and challenges inherent in relieving *** analgesia is a particularly troublesome treatment modality;these conditions are often chronic with frequent recurrences,and repeated opiate therapy can cause opioid dependency and narcotic bowel syndrome.[5]Haloperidol(HP)and droperidol,members of the butyrophenone class,have potent antidopaminergic activity in the chemoreceptor trigger zone.[6,7]Intramuscular administration of HP is being used increasingly in the ED to treat nausea,vomiting secondary to gastroparesis,[6]intractable vomiting,[8]and cyclical vomiting.

关键词： vomiting gastro treatment

Blood glucose changes surrounding initiation of tumor-necrosis factor inhibitors and conventional disease-modifying anti-rheumatic drugs in veterans with rheumatoid arthritis

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World Journal of Diabetes 2018年第2期9卷 53-58页

作者： Patrick R Wood Evan Manning Joshua F baker Bryant England Lisa Davis Grant W Cannon Ted R Mikuls Liron Caplan Denver Veterans Affairs Medical Center Division of Rheumatology University of Colorado Philadelphia Veterans Affairs Medical Center Division of Rheumatology University of Pennsylvania Omaha Veterans Affairs Medical Center Division of Rheumatology University of Nebraska Denver Health and Hospital Division of Rheumatology University of Colorado george Wahlen Veterans Affairs Medical Center Division of Rheumatology University of Utah

AIM To determine the scope of acute hypoglycemic effects for certain anti-rheumatic medications in a large retrospective observational study. METHODS Patients enrolled in the Veterans Affairs Rheumatoid Arthritis (VARA) registry were selected who, during follow-up, initiated treatment with tumor necrosis factor inhibitors (TNFi's, including etanercept, adalimumab, infliximab, golimumab, or certolizumab), prednisone, or conventional disease-modifying anti-rheumatic drugs(DMARDs), and for whom proximate random blood glucose (RBG) measurements were available within a window 2-wk prior to, and 6 mo following, medication initiation. Similar data were obtained for patients with proximate values available for glycosylated hemoglobin A1C values within a window 2 mo preceding, and 12 mo following, medication initiation. RBG and A1C measurements were compared before and after initiation events using paired t-tests, and multivariate regression analysis was performed including established comorbidities and *** Two thousands one hundred and eleven patients contributed at least one proximate measurement surrounding the initiation of any examined medication. A significant decrease in RBG was noted surrounding 653 individual hydroxychloroquine-initiation events(-3.68 mg/dL, P = 0.04), while an increase was noted for RBG surrounding 665 prednisone-initiation events(+5.85 mg/d L, P < 0.01). A statistically significant decrease in A1C was noted for sulfasalazine initiation, as measured by 49 individual initiation events(-0.70%, P < 0.01). Multivariate regression analyses, using methotrexate as the referent, suggest sulfasalazine (β =-0.58, P = 0.01) and hydroxychloroquine(β =-5.78, P = 0.01) use as predictors of lower post-medicationinitiation RBG and A1C values, respectively. Analysis by drug class suggested prednisone (or glucocorticoids) as predictive of higher medication-initiation event RBG among all start events as compared to DMARDs, while this analysis did not

关键词： Disease modifying anti-rheumatic drugs Drug toxicity Glucocorticoids Rheumatoid arthritis Tumor necrosis factor inhibitors