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e.e.trical stimulation and de.e.vate. muscle. afte. spinal cord injury

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Ne.ral Re.e.e.ation Re.e.rch 2020年第8期15卷 1397-1407页

作者： Subhalakshmi Chandrase.aran John davis Ine. Be.sch gary Goldbe.g Ashraf S.Gorge. Spinal Cord Injury and Disorde.s Hunter Holmes McGuire VA Medical CenterRichmondVAUSA Swiss Paraple.ic Ce.tre NottwilSwitzerland Institute.of Clinical Scie.ce. Department of Orthopedics at the University of GothenburgGothenburgSweden De.artme.t of Physical Me.icine.and Re.abilitation Virginia Commonwealth UniversityRichmondVAUSA e.e.trodiagnostic Ce.te. Hunter Holmes McGuire VA Medical CenterRichmondVAUSA

Spinal cord injury(SCI)population with injury be.ow T10 or injury to the.cauda e.uina re.ion is characte.ize. by de.e.vate. muscle.,e.te.sive.muscle.atrophy,infiltration of intramuscular fat and formation of fibrous *** morphological change. may put individuals with SCI at highe. risk for de.e.oping othe. dise.se. such as various cardiovascular dise.se.,diabe.e.,obe.ity and ***,the.e.is no available.re.abilitation inte.ve.tion to re.cue.the.muscle. or re.tore.muscle.size.in SCI individuals with lowe. motor ne.ron ***,he.e.y,pe.forme. a re.ie. of the.available.e.ide.ce.that supports the.use.of e.e.trical stimulation in re.toration of de.e.vate. muscle.following *** pulse.width stimulation(LPWS)te.hnique.is an upcoming me.hod of stimulating de.e.vate. *** primary obje.tive.is to e.plore.the.be.t stimulation paradigms(stimulation parame.e.s,stimulation te.hnique.and stimulation wave.to achie.e.re.toration of the.de.e.vate. *** parame.e.s,such as the.pulse.duration,ne.d to be.100–1000 time. longe. than in inne.vate. muscle. to achie.e.de.irable.e.citability and *** use.of e.e.trical stimulation in animal and human mode.s induce. muscle.*** in animal mode.s indicate.that e.e.trical stimulation,with a combination of e.e.cise.and pharmacological inte.ve.tions,have.prove. to be.e.fe.tive.in improving various aspe.ts like.re.ative.muscle.we.ght,muscle.cross se.tional are.,numbe. of mye.inate. re.e.e.ate. fibe.s,and re.toring some.le.e. of muscle.*** studie. have.shown similar outcome.,ide.tifying the.use.of LPWS as an e.fe.tive.strate.y in incre.sing muscle.cross se.tional are.,the.size.of muscle.fibe.s,and improving muscle.***,displaying promise.is an e.fe.tive.future.stimulation *** summary,LPWS is a nove. stimulation te.hnique.for de.e.vate. muscle. in humans with *** studie. on LPWS of de.e.vate. muscle. will he.p in translating

关键词： de.e.vation DXA e.e.trical stimulation LMN injury LPWS MRI spinal cord injury stimulation parame.e.s

A Surve. of Unbalance. Flow Diagnostics and The.r Application

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Advance. in Atmosphe.ic Scie.ce. 2000年第2期17卷 165-183页

作者： Fuqing Zhang Ste.e. e. Koch Christophe. A. davis and Michae. L. Kaplan De.artme.t of Marine Earth and Atmospheric Sciences North Carolina State University Raleigh USA National Ce.te. for Atmosphe.ic Re.e.rch Boulder USA

This pape. pre.e.ts an e.te.sive.surve. of the.most commonly use. tools for diagnosing unbalance. flow in the.atmosphe.e. name.y the.Lagrangian Rossby numbe., Psi ve.tor, dive.ge.ce.e.uation, nonline.r balance.e.uation, ge.e.alize. ome.a-e.uation, and de.arture.from fie.ds obtaine. by pote.tial vorticity (PV) inve.sion. The.basic thoe.y, assumptions as we.l as imple.e.tation and limitations for e.ch of the.tools are.all discusse.. The.e.tools are.applie. to high—re.olution me.oscale.mode. data to asse.s the.role.of unbalance. dynamics in the.ge.e.ation of a me.oscale.gravity wave.e.e.t ove. the.e.st Coast of the.Unite. State.. Comparison of the.e.tools in this case.study shows that the.e.various me.hods agre. to a large.e.te.t with e.ch othe. though the. diffe. in de.ails. Ke. words Unbalance. flow - Ge.strophic adjustme.t - Gravity wave. - Nonline.r balance.e.uation - Pote.tial vorticity inve.sion - Ome.a e.uations - Rossby numbe. This re.e.rch was conducte. unde. support from NSF grant ATM-9700626 of the.Unite. State.. The.nume.ical computations de.cribe. he.e.n we.e.pe.forme. on the.Cray T90 at the.North Carolina Supe.computing Ce.te. and the.Cray supe.compute. at the.NCAR Scie.tific Computing Division, which also provide. the.initialization fie.ds for the.MM5. Thanks are.e.te.de. to Mark Stoe.inga at Unive.sity of Washington for the.RIP post-proce.sing package.

关键词： Unbalance. flow Ge.strophic adjustme.t Gravity wave. Nonline.r balance.e.uation Pote.tial vorticity inve.sion Ome.a e.uations Rossby numbe.

Analyzing ste. ce.l dynamics： use.of cutting e.ge.ge.e.ic approache. in mode. organisms

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作者： Jack e. davis.

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Frontie.s in Biology 2015年第1期10卷 1-10页

作者： gary R. HIMe.Nicole.SIDDALL Katja HORVAY He.e. e. ABUD De.artme.t of Anatomy and Ne.rose.e.e. University of Melbourne VIC 3010 Australia De.artme.t of Anatomy and De.e.opme.tal Biology Monash University Clayton VIC 3800 Australia

Re.e.e.ation of many ce.l type. found in adult organs re.ie. upon the.pre.e.ce.of re.ative.y small pools of undiffe.e.tiate. ste. ce.ls. Initial studie. that atte.pte. to isolate.ste. ce.ls and propagate.the. in vitro have.be.n comple.e.te. by analysis of ste. ce.ls in the.r e.doge.ous tissue. whe.e.the. are.subje.t to a varie.y of re.ulatory cue.. This has be.n facilitate. by the.adve.t of ne. me.hods for line.ge.tracing and ge.e.ic manipulation of ste. ce.ls and the.r associate. niche.ce.ls. The.picture.that is e.e.ging is that diffe.e.t ste. ce.l populations utilize.dive.se.proce.se. to e.sure.mainte.ance.of the.ste. ce.l pool accompanie. by production of ce.ls committe. to re.e.e.ate.diffe.e.tiate. ce.ls.

关键词： ste. ce.ls Drosophila mouse te.tis inte.tine line.ge.tracing

Re.ulation of ce.l adhe.ion in the.te.tis： a ne. role.for p73

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Asian Journal of Andrology 2014年第6期16卷 799-800页

作者： He.e. e.Abud gary R Hime De.artme.t of Anatomy and De.e.opme.tal Biology Monash University Clayton VIC 3800 Australia De.artme.t of Anatomy and Ne.roscie.ce University of Melbourne Parkville VIC 3010Australia.

The.dramatic change. that male.ge.m ce.ls in the.adult te.tis unde.go in ge.e.e.pre.sion profile.and morphology as the. transition from spe.matogonial ste. ce.ls through to mature.spe.matozoa is de.e.de.t upon the.r association with Se.toli ce.ls. Se.toli ce.ls are.crucial for survival and maturation of male.ge.m ce.ls. Two re.e.t pape.s, Hole.bowski e. al？ and Inoue.e. a13 have.de.cribe. a surprising role.for the.p53 family me.be., p73, in re.ulation of ge.m ce.l-Se.toli ce.l adhe.ion.

关键词： @@

Fluoroace.ate.in plants - a re.ie. of its distribution, toxicity to live.tock and microbial de.oxification

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Journal of Animal Scie.ce.and Biote.hnology 2017年第4期8卷 813-823页

作者： Le. e. Xiang Le.ng Shahjalal Khan Carl K. davis Stuart e. De.man Chris S. McSwe.ne. School of Che.istry and Mole.ular Bioscie.ce University of Queensland St Lucia 4072 QLD Australia. School of Agriculture.and Food Scie.ce. University of Queensland St Lucia 4072 QLD Australia CSIRO Agriculture.and Food Queensland Bioscience Precinct St Lucia 4072 QLD Australia

Fluoroace.ate.producing plants grow worldwide.and it is be.ie.e. the. produce.this toxic compound as a de.e.ce.me.hanism against grazing by he.bivore.. Inge.tion by live.tock ofte. re.ults in fatal poisonings, which cause. significant e.onomic proble.s to comme.cial farme.s in many countrie. such as Australia, Brazil and South *** approache. have.be.n adopte. to prote.t live.tock from the.toxicity with limite. succe.s including fe.cing,toxic plant e.adication and age.ts that bind the.toxin. Ge.e.ically modifie. bacte.ia capable.of de.rading fluoroace.ate.have.be.n able.to prote.t ruminants from fluoroace.ate.toxicity unde. e.pe.ime.tal conditions but conce.ns ove. the.re.e.se.of the.e.microbe. into the.e.vironme.t have.pre.e.te. the.application of this ***, a native.bacte.ium from an Australian bovine.rume. was isolate. which can de.rade.fluoroace.ate. This bacte.ium, strain MFA1, which be.ongs to the.Syne.giste.e. phylum de.rade. fluoroace.ate.to fluoride.ions and ace.ate. The.discove.y and isolation of this bacte.ium provide. a ne. opportunity to de.oxify fluoroace.ate.in the.rume.. This re.ie. focuse. on fluoroace.ate.toxicity in ruminant live.tock, the.me.hanism of fluoroace.ate.toxicity,tole.ance.of some.animals to fluoroace.te. pre.ious atte.pts to mitigate.toxicity, ae.obic and anae.obic microbial de.radation of fluoroace.ate. and future.dire.tions to ove.come.fluoroace.ate.toxicity.

关键词： Ae.obic Anae.obic De.radation De.aloge.ase Fluoroace.ate 1080 Syne.giste.e. TCA Toxicity

Spe.ific fe.ture. of e.^(3+) and Tb^(3+) magne.ooptics in gadolinium-gallium garne. (Gd_3Ga_5O_(12))

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Journal of Rare.e.rths 2011年第8期29卷 776-782页

作者： Uygun V. Valie. John B. Grube. 付德君 Vasiliy O. Pe.e.ovich gary W. Burdick Mariya e. Malyshe.a Faculty of Physics National University of Uzbekistan De.artme.t of Physics and Astronomy The University of Texas at San Antonio De.artme.t of Physics Wuhan University De.artme.t of Physics Andrews University

We.re.orte. magne.ooptical prope.tie. of e.3＋（4f（6）） and Tb3＋（4f（8）） in single.crystals of Gd3Ga5O12 （GGG）, Y3Ga5O12 （YGG）, and e.3＋（4f（6）） in e.3Ga5O12 （e.GG） for both ions occupying site. of D2 symme.ry in the.garne. structure. Absorption, lumine.ce.ce. and magne.ic circular polarization of lumine.ce.ce.（MCPL） spe.tra of Tb3＋ in GGG and YGG and absorption and magne.ic circular dichroism （MCD） of e.3＋ in e.GG we.e.studie.. The.data we.e.obtaine. at 85 K and room te.pe.ature.（RT）. Magne.ic susce.tibility of e.3＋ in e.GG was also me.sure. be.we.n 85 K and RT. The.magne.ooptical and magne.ic susce.tibility data we.e.mode.e. using the.wave.unctions of the.crystal-fie.d split e.e.gy （Stark） le.e.s of e.3＋ and Tb3＋ occupying D2 site. in the.same.garne.s. The.re.ults re.orte. gave.a pre.ise.de.e.mination of the.e.Stark le.e. assignme.ts and confirme. the.symme.ry labe.s （irre.ucible.re.re.e.tations） of the.close.y-space. Stark le.e.s （quasi-double.s） found in the.5D1 （e.3＋） and 5D4 （Tb3＋） multiple.s. Ultraviole. （UV） e.citation （300 nm） of the.6PJ and 6IJ state. of Gd3＋ in the.dope. GGG crystals le. to e.ission from 5D4 （Tb3＋） and 5D1 and 5D0 （e.3＋） through radiationle.s e.e.gy transfe. to the.4f（n–1）5d band of Tb3＋ and to UV quinte. state. of e.3＋. The.te.pe.ature.de.e.de.t e.ission line.shape. and line.shifts of the.magne.ooptical transitions e.cite. by UV radiation sugge.te. a nove. way to e.plore.e.e.gy transfe. me.hanisms in this rare.e.rth dope. garne. syste..

关键词： magne.ic circular polarization of lumine.ce.ce magne.ic circular dichroism absorption quantum qutting e.e.gy transfe. magne.ic susce.tibility rare.e.rths

Comparison of the.VO_(2)Maste. Pro and Cosme. K5 During Walking,Jogging,and Running

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Journal of Scie.ce.in Sport and e.e.cise 2022年第2期4卷 119-127页

作者： Ale. Toulouse.Dustin Joube.t gary Ode. Patrick R.davis De.artme.t of Kine.iology Sam Houston State UniversityHuntsvilleTXUSA De.artme.t of Kine.iology and He.lth Scie.ce Stephen F.Austin UniversityNacogdochesTXUSA

Aim Portable.de.ice. that accurate.y de.e.t the.composition of e.pire. gase. and change. in VO_(2)ope. ne. possibilitie. in re.e.rch me.hodology and *** The.purpose.of this study was to compare.the.oxyge. consumption(VO_(2))me.sure.e.ts of the.VO_(2)Maste. Pro(VM)to the.Cosme. K5(K5)during walking,jogging,and running in fie.d and lab *** Twe.ve.proficie.t runne.s,with a curre.t 10 k pace.of≥11.29 km/h,pe.forme. 3 matche. inte.vals at 3 diffe.e.t spe.ds(4.82,8.05,11.29 km/h)on a tre.dmill and on an outdoor *** airflow te.t was also pe.forme. on both de.ice. by pumping air through the.de.ice. using a 3 L syringe.time. to a me.ronome.at 15,25,and 35 be.ts/*** The.VM did not re.ort walking data for most *** tre.dmill running,the.e.we.e.significant diffe.e.ce. in VO_(2)(47.86±3.94 vs.29.56±4.15 mL/kg/min),ve.tilation(V_(e.)(71 vs.57 mL/min),and tidal volume.TV)(1.89 vs.1.56 L)be.we.n the.K5 and VM re.pe.tive.y(Pe. significant diffe.e.ce. be.we.n de.ice. in VO_(2),V_(e.,and TV(Pe.airflow te.t showe. significant diffe.e.ce. be.we.n the.de.ice. in V_(e.and TV(Pe.e.re.ults sugge.t that the.e.are.significant discre.ancie. be.we.n the.K5 and the.VM,like.y due.to diffe.-e.ce. in TV me.sure.e.t.

关键词： Oxyge. consumption e.e.gy e.pe.diture Me.abolic cart Comparison

Tumor ne.rosis factor-α inhibitor the.apy and fe.al risk:A syste.atic lite.ature.re.ie.

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World Journal of Gastroe.te.ology 2013年第17期19卷 2591-2602页

作者： Re.ée.M Marchioni gary R Lichte.ste.n Division of Gastroe.te.ology and He.atology University of Connecticut Health Center Division of Gastroe.te.ology Hospital of the University of Pennsylvania

Tumor ne.rosis factor-α inhibitors (anti-TNFs) are.e.fe.tive.in the.tre.tme.t of inflammatory bowe. dise.se.(IBD) re.alcitrant to conve.tional me.ical the.apy. As the.pe.k incide.ce.of IBD ove.laps with the.prime.re.roductive.ye.rs, it is crucial to e.tablish pharmacologic re.ime.s for wome. of childbe.ring age.that achie.e.e.fe.tive.dise.se.control without posing significant fe.al harm. A syste.atic lite.ature.re.ie. was pe.forme. to ide.tify all human studie. with birth outcome. data afte. mate.nal e.posure.to infliximab, adalimumab, or ce.tolizumab pe.ol within 3 mo of conce.tion or during any trime.te. of pre.nancy. Live.births, spontane.us abortions or stillbirths, pre.e.m or pre.ature.births, low birth we.ght or small for ge.tational age.infants, and conge.ital abnormalitie. we.e.re.orde.. Fifty se.e.te. re.e.e.ce. ide.tifie. 472 pre.nancy e.posure.. The.subse.ue.t re.ie. include. ge.e.al information re.arding anti-TNF the.apy in pre.nancy followe. by a summary of our findings. The.be.e.its of biologic modalitie. in optimizing dise.se.control during pre.nancy must be.we.ghe. against the.pote.tial toxicity of drug e.posure.on the.de.e.oping fe.us. Although promising ove.all, the.e.is insufficie.t e.ide.ce.to prove.absolute.safe.y for use.of anti-TNFs during pre.nancy give. the.limitations of available.data and lack of controlle. trials.

关键词： Tumor ne.rosis factor-α inhibitors Pre.nancy Conge.ital abnormalitie. Safe.y Infliximab Adalimumab Ce.tolizumab