Regulation of cell adhesion in the testis： a new role for p73

作     者：Helen E Abud Gary R Hime 

作者机构：Department of Anatomy and Developmental BiologyMonash University Clayton VIC 3800 Australia Department of Anatomy and NeuroscienceUniversity of Melbourne Parkville VIC 3010Australia. 

出 版 物：《Asian Journal of Andrology》 (亚洲男性学杂志（英文版）)

年 卷 期：2014年第16卷第6期

页      面：799-800页

核心收录：

学科分类：0710[理学-生物学] 1002[医学-临床医学] 07[理学] 08[工学] 09[农学] 071009[理学-细胞生物学] 071007[理学-遗传学] 0901[农学-作物学] 0836[工学-生物工程] 090102[农学-作物遗传育种] 

主　　题：TUMOR-SUPPRESSOR P63 SPERMATOGENESIS TAP73 DEATH P53 

摘      要：The dramatic changes that male germ cells in the adult testis undergo in gene expression profile and morphology as they transition from spermatogonial stem cells through to mature spermatozoa is dependent upon their association with Sertoli cells. Sertoli cells are crucial for survival and maturation of male germ cells. Two recent papers, Holembowski et al？ and Inoue et a13 have described a surprising role for the p53 family member, p73, in regulation of germ cell-Sertoli cell adhesion.