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Structure design and property adjustment of new cage rich-nitrogen pentazolyltetraazacubanes as potential high energy density compounds

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Defence Technology（防务技术） 2020年第3期16卷 705-711页

作者： Qiong Wu gao-jie Yan Ze-wu Zhang Wei-hua Zhu School of Materials Science and Engineering Nanjing Institute of Technology1 Hongjing RoadNanjing 211167China Jiangsu Key Laboratory of Advanced Structural Materials and Application Technology 1 Hongjing RoadNanjing 211167China Institute for Computation in Molecular and Materials Science and Department of Chemistry Nanjing University of Science and TechnologyNanjing 210094China

In this study,based on two attractive energetic compounds pentazole(PZ) and tetraazacubane(TAC),a new family of high energy and high nitrogen compounds pentazolyltetraazacubanes were ***,a different number of NH2 or NO2 groups were introduced into the system to further adjust the *** structures,properties,and the structure-property relationship of designed molecules were investigated *** results showed that all nine designed compounds have extremely high heat of formation(HOF,1226-2734 kJ/mol),good density(1,73-1.88 g/cm3),high detonation velocity(8.30-9.35 km/s),high detonation pressure(29.8-39.7 GPa) and acceptable sensitivity(△V:41-87 A3).These properties could be effectively positive adjusted by replacing one or two PZ rings by NH2 or/and NO2 groups,especially for the energy and sensitivity performance,which were increased and decreased obviously,*** a result,two designed pentazolyltetraazacubanes were predicted to have higher energy and lower sensitivity than the famous high energy compound in use 1,3,5,7-tetranitro-1,3,5,7-tetraazacyclooctane,while two others have better co mbination property than 1,3,5-Trinitro-1,3,*** all,four new pentazolyltetraazacubanes with good combination performance were successfully designed by combining PZ with TAC,and the further property adjustment strategy of introducing a suitable amount of NH2/NO2 groups into the *** work may help develop new cage energetic compounds.

关键词： Pentazole Cubane High-nitrogen High-energy HEDCs

Land development suitability analysis for transport planning evaluation and optimization in mountainous ecological region

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Journal of Mountain Science 2022年第3期19卷 862-873页

作者： ZHU gao-ru WANG Man LI Qi-li LIU Jie ZHAO Yan-ni gao Jia-wei XU Hong-lei Laboratory of Transport Pollution Control and Monitoring Technology Transport Planning and Research InstituteMinistry of TransportBeijing 100028China College of Urban and Environmental Sciences Peking UniversityBeijing 100871China Key Laboratory for Environmental and Urban Sciences School of Urban Planning&DesignShenzhen Graduate SchoolPeking UniversityShenzhen 518055China

Transportation planning is a critical component for creating an orderly,intensive,and sustainable pattern of land *** comprehensively considering the potential and suitability of transport construction,a comprehensive method combining resources and environmental carrying capacity(RECC)and land development suitability(LDS)was developed by using techniques of GIS,analytic hierarchy process(AHP)and threedimensional magic *** Aba prefecture in Sichuan Province of Southwest China as a case study,LDS for transportation was analyzed from three aspects,including overall planning layout,different transport modes,and transportation *** results showed that the transport planning scales of most counties in Aba were suitable,and the order of LDS of different transport modes was railway>highway=superhighway>tourism track,which already included 42 new transportation *** found that two counties(Maoxian County and Jiuzhaigou County)should improve the ecological protection level of transportation,in which the railway network construction should be encouraged,and some transportation projects with low LDS should be postponed or constructed *** suggest the combination of RECC and LDS for transportation could enhance the territorial space optimization and sustainable transport construction.

关键词： Land development suitability Resources and environment carrying capacity Transport planning Evaluation Optimization Spatial analysis Mountainous ecological region

“PALPATION BY IMAGING”:MAGNETIC RESONANCE ELASTOGRAPHY

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Chinese Medical Sciences Journal 2006年第4期21卷 281-286页

作者： Lei Xu Pei-yi gao Imaging Center of Neuroscience Beijing Tiantan Hospital Capital University of Medical Sciences Beijing 100050

Elasticity is an important physical property of human tissues. There is a tremendous difference in elasticity between normal and pathological tissues. Noninvasive evaluation of the elasticity of human tissues would be valuable for clinical practice. Magnetic resonance elastography(MRE)is a recently developed noninvasive imaging technique that can directly visualize and quantitatively measure tissue elasticity. This article reviewed the MRE technique and its current status.

关键词： magnetic resonance imaging elasticity tissue characterization

NUMERICAL SIMULATIONS OF THE HYDRAULIC CHARACTERISTICS OF SIDE INLET/OUTLETS

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Journal of Hydrodynamics 2011年第1期23卷 48-54页

作者： YE Fei gao Xue-ping North China University of Water Conservancy and Electric Power Zhengzhou 450011 China School of Civil Engineering Tianjin University Tianjin 300072 China

The hydraulic characteristics at the side inlet/outlet of pumped storage plants is studied by numerical simulations,covering the flow distribution,head loss,vortex,and *** on the physical model test,the realizable k-εturbulence model is used in the 3-D simulation of the side inlet/outlet.A new scheme is suggested to obtain the uneven flow distribution over three branch *** variation of the free surface with the reservoir water level under the pumped condition is simulated,with results consistent with the experimental results.

关键词： hydraulic characteristics side inlet/outlet pumped storage plant numerical simulation realizable k-εturbulence model

The existence of radial k-admissible solutions for n-dimension system of k-Hessian equations

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Applied Mathematics(A Journal of Chinese Universities) 2023年第2期38卷 310-316页

作者： HE Xing-yue WANG Jing-jing gao Cheng-hua Department Mathematics and Statistics Northwest Normal UniversityLanzhou 730070China

In this paper,we focus on a general n-dimension system of k-Hessian *** introducing some new suitable growth conditions,the existence results of radial k-admissible solutions of the k-Hessian system are *** approach i... 详细信息

关键词： k-Hessian equations radial k-admissible solutions existence xed-point theorem

Comparison of toxicity effects of fuel oil treated by different dispersants on marine medaka(Oryzias melastigma) embryo

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Acta Oceanologica Sinica 2018年第11期37卷 123-132页

作者： gao Xiang DING Guanghui LI Xishan XIONG Deqi College of Environmental Science and Engineering Dalian Maritime University

This study aims to evaluate the subacute toxic effects of oil under different treatments on marine organism by simulating natural contaminative processes. In this study, 120# （RMD15） fuel oil was selected as the pollutant and marine medaka （Oryzias melastigma） embryos as the experimental organism. The developmental toxicity of different volume concentrations （0.05%, 0.2%, 1% and 5%） of water-accommodated fractions, biologically-enhanced water-accommodated fractions, and chemically-enhanced water-accommodated fractions on the embryos in different exposure time （8, 15 and 22 d） were compared and the content of relevant polycyclic aromatic hydrocarbons （PAHs） was studied （in dispersion and in vivo）. The subacute toxic effects were assessed in terms of antioxidant activities of enzymes （superoxide dismutase, catalase and glutathione S-transferase） and the blue sac disease （BSD） *** results showed that the BSD indexes of the treatment groups were significantly higher than the respective control groups and showed positive correlations with both concentration and exposure time. The experiments with three antioxidant enzymes indicated that enzymatic activities of the embryos changed dramatically under the oxidation stress of petroleum hydrocarbons, especially after adding the dispersants. With the increase of petroleum hydrocarbon concentration and exposure time, the three enzymes showed different degrees of induction and inhibition effects.

关键词： marine medaka petroleum hydrocarbon oil dispersant antioxidant enzymes 120# fuel oil

Application of yeast spores as β-glucan particles

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Particuology 2022年第12期71卷 34-40页

作者： Guoyu Liu Yan Yang Hiroyuki Tachikawa Xiao-Dong gao Hideki Nakanishi Key Laboratory of Carbohydrate Chemistry and Biotechnology Ministry of EducationSchool of BiotechnologyJiangnan UniversityWuxi 214122China Department of Applied Biological Chemistry Graduate School of Agricultural and Life SciencesUniversity of TokyoTokyo 113-8657Japan Collaborative Research Institute for Innovative Microbiology University of TokyoTokyo 113-8657Japan

β-Glucan exhibits various beneficial biological activities including *** polysaccha-ride is present in the cell wall of microorganisms including the yeast Saccharomyces *** vegetative yeast cells are used as dietary supplements,β-glucan in the vegetative cell wall is covered with *** nutrient starvation,yeast cells differentiate into dormant cell spores.β-Glucan is also present in the spore wall,but spores have been poorly studied as application *** spore wall consists of four layers andβ-glucan forms the third layer from the ***,unlike vegeta-tive cells,theβ-glucan layer can be exposed to the cell surface in spores by genetic *** example,chs3Δmutant spores exhibit such a spore wall ***-1 is the primary receptor forβ-glucan in mammals and,its activation induces phagocytosis and proinflammatory cytokine *** found that chs3Δspores are phagocytosed in mammalian cells in a manner dependent on dectin-1 and induce higher levels of TNF-αand IL-6 than vegetative *** results demonstrate that chs3Δspores areβ-glucan particles with immunostimulatory ***,they would be attractive materials for application in the food industry.

关键词： Saccharomycescerevisiae Sporewall β-glucan Dectin-1 Immunostimulation

SPECTRAL PROPERTIES OF DISCRETE STURM-LIOUVILLE PROBLEMS WITH TWO SQUARED EIGENPARAMETER-DEPENDENT BOUNDARY CONDITIONS

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Acta Mathematica Scientia 2020年第3期40卷 755-781页

作者： Chenghua gao Yali WANG Li LV Department of Mathematics Northwest Normal UniversityLanzhou 730070China

In this article,we consider a discrete right-definite Sturm-Liouville problems with two squared eigenparameter-dependent boundary *** constructing some new Lagrange-type identities and two fundamental functions,we obtain not only the existence,the simplicity,and the interlacing properties of the real eigenvalues,but also the oscillation properties,orthogonality of the eigenfunctions,and the expansion ***,we also give a computation scheme for computing eigenvalues and eigenfunctions of specific eigenvalue problems.

关键词： Discrete Sturm-Liouville problems squared eigenparameter-dependent boundary conditions interlacing oscillation properties orthogonality

Health benefits of Grifola frondosa polysaccharide on intestinal microbiota in type 2 diabetic mice

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Food Science and Human Wellness 2022年第1期11卷 68-73页

作者： Xiaoxiang gao Dan Liu Luying gao Yuezhen Ouyang Yuxi Wen Chao Ai Yuqing Chen Chao Zhao College of Food Science Fujian Agriculture and Forestry UniversityFuzhou 350002China Department of Pediatrics Nanjing First HospitalNanjing Medical UniversityNanjing 210006China School of Food Science and Engineering South China University of TechnologyGuangzhou 510641China Department of Food Science&Technology National University of SingaporeSingapore 117543Singapore Engineering Research Centre of Fujian-Taiwan Special Marine Food Processing and Nutrition Ministry of Education Fuzhou 350002China

Grifola frondosa polysaccharide(GFP)as the natural compounds have been reported to exert diverse *** aim of this study was to investigate the regulatory effects of GFP on intestinal microbiota in type 2 diabetic *** changes of microbiota in faeces of the diabetic mice upon high fat diet were determined and the V3 region of the 16S rRNA was sequenced by Illumina MiSeq high-throughput sequencing *** operational taxonomic unit were identified to be shared by all samples,and the quality and richness of sequencing were assessed via rarefaction and rank abundance *** diversity of gut flora was slightly improved in diabetic mice after GFP *** composition and relative abundance of gut microbiota at phylum and genus levels were altered by *** abundance of Robinsoniella,Flavonifractor,Anaerotruncus,and Desulfvibrio were found to concentrate on diabetic mice through LEfSe ***,Alloprevotella and Burkholderia had strong relevancy with other gut *** on the findings,GFP might be a desired candidate on ameliorating the intestinal unbalance in diabetes.

关键词： Maitake Grifola frondosa polysaccharide Diabetes Gut microbiota