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Calculation of Coronary Angiographic Total Blush in Patients with Coronary Artery Disease and its Prognostic Implication

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Chinese Medical Journal 2015年第18期128卷 2485-2490页

作者： jing-jing gai Lu-Yue gai Jian-Jun Yan Qin-Hua Jin Department of Cardiology Chinese People's Liberation Army General Hospital Beijing 100853 China

Background： Myocardial perfusion grade （MPG） is an accepted method of evaluating myocardial perfilsion. However, it does not take into the account, the extent of the perfusion. We hypothesized that myocardial blush area times MPG （total blush） would be more accurate than simple MPG, and yield better prognostic information. Methods： About 34 patients were recruited alter they had consented to both coronary angiography （CAG） and single photon emission computed tomography （SPECT）, and divided into two groups. A special dedicated computer was employed to calculate the total blush. The CAG was performed as a conventional way. Scintigraphic technetium 99m methoxyisobutyl-isonitrile rest and stress images were evaluated quantitatively. The comparison was made between stenosis versus chronic total occlusion （CTO）, MPG 1, 2 versus MPG 3, percutaneous intervention （PC1） successful versus failure. A correlation was made between ejection traction （EF） and myocardial perfusion by MPG, total blush, SPECT, and syntax score. Results： The perfusion indices of total blush, summed difference score （SDS） and syntax score were insignificant between the two groups （P 〉 0.05）. However, the left ventricular end diastolic volume was significantly larger in CTO （P 〈 0.05）. The patients with stenosis had better MPG than with CTO （P 〈 0.05）. The increased MPG was associated with increased total blush, higher syntax score, and EF （P 〈 0.05）. Successful PCI resulted in better perfusion indicated by increased total blush, and MPG （P 〈 0.05） but successful PC1 did not change syntax score. EF and SDS significantly. Multivariate linear analysis with EF as the dependent factor and syntax score, SDS, total blush, blush area, and MPG as the independent factors showed a significantly higher degree of correlation （R = 0.87, P 〈 0.05）. Conclusion： Alter PCI the total blush and EF improved significantly indicating its potential application in the thture.

关键词： Coronary Heart Disease: Ejection Fraction Myocardial Perfusion Percutaneous Coronary Intervention: Single PhotonEmission Computed Tomography Syntax Score

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Four-year clinical outcome in asymptomatic patients undergoing coronary computed tomography angiography

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Chinese Medical Journal 2013年第9期126卷 1630-1635页

作者： ZHANG Kai-yi gai Lu-yue gai jing-jing HE Bin GUAN Zhi-wei Department of Cardiology Chinese People's Liberation Army General Hospital Beijing 100853 China Hospital of General Political Department of Chinese People's Liberation Army Beijing 100120 China

Background Percutaneous coronary intervention （PCI） is indicated for angina with coronary stenosis. However, PCI for asymptomatic coronary stenosis remains controversial. We prospectively followed a group of patients for four years who underwent coronary computed tomography angiography （CCTA） for major adverse cardiac events （MACE）. We hypothesized that the results of this trial would reliably reflect the natural outcome of the coronary disease. Methods Consecutive patients who underwent CCTA from June 2008 to May 2009 were selected. Those who could not be reached by telephone, had significant angina, had CT images that were not interpretable, or poor kidney and left ventricular （LV） function were excluded. The patients were divided into five groups： group A normal CCTA without stenosis, group B mild stenosis （1%-49%）, group C moderate stenosis （50%-74%）, group D severe stenosis （≥75%） and they were treated with optimal medical therapy （OMT） or PCI. The group E had PCI before the CCTA examination. The patients were then followed for MACE after different treatments. MACE included acute myocardial infarction （MI）, heart failure （HF） and death. Results The patient population consisted of 419 patients. The follow-up time was （51±5） months. The age was （60±31） years. Male made up 67.78% of the population （n=284）. A total of 51 cases of MACE occurred including 25 MI, eight HF and 18 all-cause deaths. There was no MACE in group A. Although MACE occurred in two patients in group B, they were not attributed to cardiac death. We further compared the MACE in groups C-E and no significant difference was found （P 〉0.05）. However, a difference was detected among patients with unstable angina pectods （UAP）, stable angina pectoris （SAP）, re-hospitalization, and cerebrovascular events from groups A-E （P 〈0.05）. The plaque scores were used to predict MACE. The scores progressively increased significantly with lesion severity （P 〈0.05）. Receiver operating curve （ROC） was performed to

关键词： coronary computed tomography angiography optimal medical therapy percutaneous coronary intervention coronary artery disease

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Research Progress in Early-onset Colorectal Cancer

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Journal of Clinical and Nursing Research 2024年第6期8卷 201-205页

作者： jing Li Haoyuan Guo jing Yu Zhibo gai Department of Pathology Changqing District People's HospitalJinan 250300China School of Medicine Shandong University of Traditional Chinese MedicineJinan 250300China Pathology Department of Shandong Provincial Third Hospital Jinan 250000China Experimental Center of Shandong University of Traditional Chinese Medicine Jinan 250300China

Colorectal cancer used to be a common disease among middle-aged and elderly *** recent years,the incidence of colorectal cancer(Early-onset colorectal cancer,EOCRC)under 50 years old has increased year by *** from the traditional late-onset colon cancer(LOCRC),the diagnosis stage of EOCRC is mostly in the late stage,with poor cell differentiation and poor diagnosis,and there is a layer of consensus and guidance on the diagnosis,treatment or screening of EOCRC at ***,fully understanding the disease characteristics and risk exposure factors of EOCRC is helpful to guide early screening and treatment,which ultimately reduces the mortality of *** this review article,we summarized the epidemiology,physiology,risk exposure factors and pathological diagnosis of EOCRC,and discussed the diagnosis and treatment prospect of EOCRC.

关键词： Early-onset colorectal cancer Epidemiological investigation Phylogeny Exposure factors Pathological prognosis

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Neovascularization in the carotid atherosclerotic plaque is not associated with inflammatory cell aggregation

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Chinese Medical Journal 2013年第16期126卷 3073-3078页

作者： gai jing-jing LIU Hong-bin LI Juan XIE Lei-xing ZHAO Xi-hai CHENG Liu-quan CHEN Hui-jun WANG Yong YIN Da-yi LIU Jia-jin ZHANG Xiong-wei Department of Cardiology Chinese People's Liberation Army General Hospital Beijing 100853 China Department of Radiology Chinese People's Liberation Army General Hospital Beijing 100853 China Department of Nuclear Chinese People's Liberation Army General Hospital Beijing 100853 China Centre for Biomedical Imaging Research Tsinghua University Beijing 100084 China Vascular Imaging Laboratory University of Washington Seattle WA 98109 USA

Background Monocytes and macrophages in atherosclerotic plaque lead to plaque *** aim of the study was to determine if plaque neovascularization led to *** Patients were consecutively enrolled if their carotid intimal media thickness was ＞2 mm,as revealed by duplex *** patients then underwent dynamic contrast enhanced magnetic resonance imaging （DCE MRI） and fluorine-18 fluorodeoxyglucose （18F-FDG） positron emission tomography combined with computed tomography （PET CT）.A target to background ratio （TBR） of ＞1.25 or ＜1.25 served as the cutoff point for the presence and absence of inflammation,*** Twenty-six patients underwent bilateral carotid DCE MRI and 24 patients also underwent PET *** hundred and fifty-five plaques were evaluated by both DCE MRI and PET *** was no significant difference in plaque morphology between the TBR ＞1.25 （n=61） and TBR ＜1.25 （n=94） *** significant differences were found in plasma volume and transfer constant between the TBR ＞1.25 and TBR ＜1.25 *** Our study did not find a significant correlation between plaque neovascularization and the aggregation of inflammatory cells.

关键词： carotid atherosclerosis dynamic contrast enhanced magnetic resonance imaging positron emission tomography macrophages,neovascularization

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关注急性冠状动脉综合征、左心衰竭和肾动脉狭窄的关系

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中华内科杂志 2010年第12期49卷 995-996页

作者：盖鲁粤盖兢泾解放军总医院心内科北京100853

心脏和肾脏有着千丝万缕的联系。早在20世纪80年代初人们就开始注意到，慢性肾衰竭的患者存在很多冠心病的危险因素，如高胆固醇血症、糖尿病、高血压、左心功能不全等。即使轻度的肾小球滤过率降低也伴随了心血管疾病病死率的增高。

关键词：急性冠状动脉综合征肾动脉狭窄左心衰竭高胆固醇血症左心功能不全肾小球滤过率慢性肾衰竭心血管疾病

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The plaque characteristics of before and after major coronary events:a coronary computed tomography angiography and coronary angiography correlative study

The plaque characteristics of before and after major coronar...

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第十三次全国心血管病学术会议

作者： gai Lu-yue,HE Bin,gai jing-jing,CHEN Yun-dai,GUAN Zhi-wei,YANG Li *Department of Cardiology.Chinese PLA General Hospital, Beijing 100001,China

Objective Acute myocardial infarction often occurs suddenly without *** mortality and morbidity are high. Study of the plaque Characteristics of before and after major coronary events will help forecasting the *** The pts who underwent Coronary Computed Tomography Angiography(CCTA) from january 2008 to February 2010 were included in the *** patient who developed acute ST elevated myocardial infarction(STEMI) or non ST elevated acute

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首选冠状动脉CT评估可提高冠心病再血管化的准确性

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中国中西医结合急救杂志 2013年第4期20卷 230-233页

作者：翟学盖鲁粤张闿艺盖兢泾南开大学医学院天津300017 解放军总医院心血管内科北京100853

目的探讨冠状动脉（冠脉）CT（CCTA）引导对冠心病再血管化准确性的影响。方法采用回顾性研究方法，连续选择2008年至2009年解放军总医院先行CCTA后行冠脉造影（CAG）的605例患者（CCTA后CAG组），同期选择未进行CCTA直接行CAG的616例... 详细信息

目的探讨冠状动脉（冠脉）CT（CCTA）引导对冠心病再血管化准确性的影响。方法采用回顾性研究方法，连续选择2008年至2009年解放军总医院先行CCTA后行冠脉造影（CAG）的605例患者（CCTA后CAG组），同期选择未进行CCTA直接行CAG的616例患者（直接CAG组）；比较两组治疗策略选择的比例，包括经皮冠脉介入治疗（PCI）、冠脉旁路移植术（CABG）、药物治疗策略、CAG的正常率和再血管化的准确性。结果基线资料显示，CCTA后CAG组患者病变程度（Syntax积分）略高于直接CAG组〔（11.31±8.90）分比（10.23±9.73）分，P＜0.05〕。与直接CAG组比较，CCTA后CAG组行PCI、CABG的比例明显增加〔PCI：65.3%（395/605）比57.1%（352/616），CABG：16.5%（100/605）比3.4%（21/616）〕，药物治疗和CAG正常率明显减少〔药物治疗：11.7%（71/605）比19.3%（119/616），CAG正常率：6.4%（39/605）比20.1%（124/616）〕，再血管化的准确性明显增加〔81.8%（495/605）比60.6%（373/616），均P＜0.01〕。结论与CAG引导相比，CCTA引导下可以提高冠心病再血管化的准确性。

关键词：冠状动脉CT 冠状动脉造影冠心病再血管化

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患者检验结果缺失的根本原因分析

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现代医院管理 2024年第4期22卷 37-39页

作者：宋景晨盖媛媛窦婧婧北京医院/国家老年医学中心/中国医学科学院老年医学研究院北京市100730

对医院发生的患者检验结果缺失的事件进行分析,成立RCA小组进行调研并确认问题;运用基于时间的流程图梳理事件,运用问卷和鱼骨图法分析事件发生原因,使用查检表和“5W1H”制定整改对策,进行流程优化、精准培训、优化检验项目和升级信息... 详细信息

对医院发生的患者检验结果缺失的事件进行分析,成立RCA小组进行调研并确认问题;运用基于时间的流程图梳理事件,运用问卷和鱼骨图法分析事件发生原因,使用查检表和“5W1H”制定整改对策,进行流程优化、精准培训、优化检验项目和升级信息系统等,加强各部门的沟通合作、优化专业工作流程,全面构建医院安全文化,是可以避免此类事件发生的有效手段。

关键词：结果缺失根本原因分析患者安全流程优化

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图文互证:论汉文摩尼教文献所见“电光佛”“电光王佛”为光明少女

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艺术探索 2024年第3期38卷 54-63页

作者：刘璟盖佳择故宫博物院北京100006 淮阴师范学院图书馆江苏淮阴223001

“电光佛”“电光王佛”所指为光明少女当是无可置疑的,无论是敦煌还是霞浦、屏南发现之摩尼教文献,并无一处文字指向电光(王)佛为所谓大明尊或电那勿者。电光(王)佛(光明少女)绝不仅仅是诱惑暗魔的工具神,而是能兴云致雨、擒捉魔首的... 详细信息

“电光佛”“电光王佛”所指为光明少女当是无可置疑的,无论是敦煌还是霞浦、屏南发现之摩尼教文献,并无一处文字指向电光(王)佛为所谓大明尊或电那勿者。电光(王)佛(光明少女)绝不仅仅是诱惑暗魔的工具神,而是能兴云致雨、擒捉魔首的闪电神,后更有干预冥判、裁判灵魂之大能。她从未因华情之“不允”而在中原摩尼教中销声匿迹,却因其悲悯之怀最终跻身摩尼教“三佛”之列。

关键词：光明少女电光佛电光王佛云雨

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静电纺丝导电纳米纤维膜的研究进展

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合成纤维 2023年第4期52卷 33-40页

作者：徐治君金旭盖京京丁姗姗李秀艳汪滨北京服装学院材料设计与工程学院北京100029 北京服装学院、服装材料研究开发与评价北京市重点实验室北京100029 北京服装学院、北京市纺织纳米纤维工程技术研究中心北京100029

由于具有电导率可调、比表面积大、自支撑、柔性等优点,导电纳米纤维膜材料的研究日益受到关注。静电纺丝技术结合涂层包覆法、超声包覆法、原位聚合包覆法等化学方法是制备导电纳米纤维膜材料最简单、有效的工艺。首先简单介绍了静电... 详细信息

由于具有电导率可调、比表面积大、自支撑、柔性等优点,导电纳米纤维膜材料的研究日益受到关注。静电纺丝技术结合涂层包覆法、超声包覆法、原位聚合包覆法等化学方法是制备导电纳米纤维膜材料最简单、有效的工艺。首先简单介绍了静电纺丝技术,然后按照导电材料的种类对导电纳米纤维膜的制备工艺进行了归纳总结,最后综述了近几年导电纳米纤维膜材料在生物工程、电磁屏蔽防护和柔性传感器等领域的探索进展。

关键词：静电纺丝导电纳米纤维膜生物工程电磁屏蔽防护柔性传感器

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