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Turbulent hydrodynamics experiments in hig. energ. density plasmas： scientific case and preliminary results of the TurboHEDP project

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Hig. Power Laser Science and Eng.neering 2018年第3期6卷 50-64页

作者： A. Casner g. rigon B. Albertazzi Th. Michel T. Pikuz A. Faenov P. Mabey N. Ozaki Y. Sakawa T. Sano J. Ballet P. Tzeferacos D. Lamb E. Falize g. g.eg.ri M. Koenig Universite de Bordeaux-CNRS-CEA CELIA (CEntre Lasers Intenses et Applications) UMR 5107 F-33405 Talence France LULI- CNRS Ecole Polytechnique CEA Universite Paris-Saclay UPMC Univ Paris 06 : Sorbonne Universites -F-91128 Palaiseau cedex France ENS Lyon Universite de Lyon CHELS 69342 Lyon France Open and Transdisciplinary Research Initiatives Osaka University Suita Osaka 565-0871 Japan Joint Institute for Hig. Temperature RAS Moscow 125412 Russia g.aduate School of Eng.neering Osaka University Suita Osaka 565-0871 Japan Institute of Laser Eng.neering Osaka University Suita Osaka 565-0871 Japan Laboratoire AIM CEA-IRFU/CNRS/Universite Paris Diderot Departement d'Astrophysique CEA Saclay F-91191 Gif sur Yvette France Flash Center for Computational Science University of Chicago USA CEA DAM DIF F-91297 Arpajon France Clarendon Laboratory University of Oxford Parks Road Oxford OX1 3PU UK

The physics of compressible turbulence in hig. energ. density(HED) plasmas is an unchartered experimental *** of compressible and radiative flows relevant for astrophysics rely mainly on subscale parameters. Therefore,we plan to perform turbulent hydrodynamics experiments in HED plasmas(TurboHEDP) in order to improve our understanding.of such important phenomena for interest in both communities: laser plasma physics and astrophysics. We will focus on the physics of supernovae remnants which are complex structures subject to fluid instabilities such as the Rayleig.–Taylor and Kelvin–Helmholtz instabilities. The advent of meg.joule laser facilities, like the National Ig.ition Facility and the Laser Meg.joule, creates novel opportunities in laboratory astrophysics, as it provides unique platforms to study turbulent mixing.flows in HED plasmas. Indeed, the physics requires accelerating.targ.ts over larg.r distances and long.r time periods than previously achieved. In a preparatory phase, scaling.from experiments at lower laser energ.es is used to g.arantee the performance of future MJ experiments. This subscale experiments allow us to develop experimental skills and numerical tools in this new field of research, and are stepping.stones to achieve our objectives on larg.r laser facilities. We review first in this paper recent advances in hig. energ. density experiments devoted to laboratory astrophysics. Then we describe the necessary steps forward to commission an experimental platform devoted to turbulent hydrodynamics on a meg.joule laser facility. Recent novel experimental results acquired on LULI2000, as well as supporting.radiative hydrodynamics simulations, are presented. Tog.ther with the development of LiF detectors as transformative X-ray diag.ostics, these preliminary results are promising.on the way to achieve micrometric spatial resolution in turbulent HED physics experiments in the near future.

关键词： hig. energ. density physics inertial confinement fusion laboratory astrophysics plasmas astrophysics

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Development of new diag.ostics based on LiF detector for pump-probe experiments

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Matter and Radiation at Extremes 2018年第4期3卷 197-206页

作者： T.Pikuz A.Faenov NOzaki T.Matsuoka B.Albertazzi N.J.Hartley K.Miyanishi K.Katag.ri S.Matsuyama K.Yamauchi H.Habara Y.Inubushi T.Tog.shi H.Yumoto H.Ohashi Y.Tang. T.Yabuuchi M.Yabashi A.N.g.um-g.zhimailo A.Casner I.Skobelev S.Makarov S.Pikuz g.rigon M.Koenig.K.A.Tanaka T.Ishikawa R.Kodama g.aduate School of Eng.neering Osaka UniversitySuitaOsaka 565-0871Japan Joint Institute for Hig. Temperatures Russian Academy of SciencesMoscow 125412Russia Open and Transdisciplinary Research Initiatives Osaka UniversitySuitaOsaka 565-0871Japan Photon Pioneers Center Osaka UniversitySuitaOsaka 565-0871Japan LULI e CNRS Ecole PolytechniqueCEA:Universite Paris-SaclayUPMC Univ Paris 06:Sorbonne Universites-F-91128 Palaiseau cedexFrance Helmholtz-Zentrum Dresden-Rossendorf Dresden 01328Germany Japan Synchrotron Radiation Research Institute Sayo-choSayo-gunHyogo 679-5198Japan RIKEN Spring.8 Center Sayo-choSayo-gunHyogo 679-5148Japan Skobeltsyn Institute of Nuclear Physics Lomonosov Moscow State UniversityMoscow 119991Russia Universite de Bordeaux-CNRS-CEA CELIA(Center Lasers Intenses et Applications)UMR 5107F-33405 TalenceFrance National Research Nuclear University MEPhI Moscow 115409Russia ELI-NP/IFN-HH Maqurele-Bucharest 077125 Romania ILE Osaka UniversitySuitaOsaka 565-0871Japan

We present new diag.ostics for use in optical laser pump-X-ray Free Electron Laser(XFEL)probe experiments to monitor dimensions,intensity profile and focusability of the XFEL beam and to control initial quality and homog.neity of targ.ts to be driven by optical laser *** developing.X-ray imag.ng.based on the use of an LiF crystal detector,we were able to measure the distribution of energ. inside a hard X-ray beam with unprecedented hig. spatial resolution(~1 mm)and across a field of view larg.r than some *** diag.ostic can be used in situ,provides a very hig. dynamic rang.,has an extremely limited cost,and is relatively easy to be implemented in pump-probe *** proposed methods were successfully applied in pump-probe experiments at the SPring.8 Ang.trom Compact free electron LAser(SACLA)XFEL facility and its potential was demonstrated for current and future Hig. Energ. Density Science experiments.

关键词： XFEL Shock waves Pump-probe experiments Hig. energ. density science X-ray spectroscopy X-ray imag.ng

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Phase Contrast Micro-Computed Tomog.aphy of Biolog.cal Sample at SSRF

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Tsing.ua Science and Technolog. 2010年第1期15卷 102-107页

作者：陈荣昌谢红兰 Luig. rigon 杜国浩 Edoardo Castelli 肖体乔 Shang.ai Institute of Applied Physics Chinese Academy of Sciences Department of Physics University of Trieste INFN Sezione di Trieste

In line X-ray phase contrast micro-computed tomog.aphy （IL-XPCT）, which can be implemented at third g.neration synchrotron radiation sources or by using.a micro-focus X-ray tube, is a powerful technique for non-destructive, hig.-resolution investig.tions of a broad variety of materials. At the Shang.ai Synchrotron Radiation Facility （SSRF）, the X-ray Imag.ng.and Biomedical Applications Beamline was built and started reg.lar user operation in May 2009. Both qualitative （without phase retrieval） and quantitative （with phase retrieval） three-dimensional IL-XPCT experimental techniques have been established at the beamline IL-XPCT experiments of a test sample （plastic pipes） used to evaluate the technique, and of a biolog.cal sample （locust） at the beamline are reported. Two series of imag.s, qualitative and quantitative, including.tomog.aphic slices and three-dimensional rendering.imag.s were obtained. In qualitative imag.s, there is a strong.edg.-enhancement which leads to very clear sample contours, while in quantitative imag.s, the edg.-enhancement fades but quantitative measurement of sample＇s phase information could be achieved. The experiments demonstrate that the combination of qualitative and quantitative imag.s is useful for biolog.cal sample studies.

关键词： X-ray phase contrast tomog.aphy phase retrieval synchrotron radiation

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In vivo tracking.of tau patholog. using.positron emission tomog.aphy (PET) molecular imag.ng.in small animals

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Translational Neurodeg.neration 2014年第1期3卷 34-39页

作者： Eduardo rigon Zimmer Antoine Leuzy Venkat Bhat Serg. g.uthier Pedro Rosa-Neto Translational Neuroimag.ng.Laboratory(TNL) McGill Center for Studies in AgingDouglas Mental Health University InstituteMcGill University6875 La Salle Blv-FBC room 3149MontrealQCH4H 1R3Canada Montreal Neurolog.cal Institute(MNI) MontrealCanada Department of Biochemistry Federal University of Rio Grande do Sul(UFRGS)Porto AlegreBrazil Department of Psychiatry McGill UniversityMontrealBrazil

Hyperphosphorylation of the tau protein leading.to the formation of neurofibrillary tang.es(NFTs)is a common feature in a wide rang. of neurodeg.nerative diseases known as tauopathies,which include Alzheimer’s disease(AD)and the frontotemporal dementias(FTDs).Althoug. heavily investig.ted,the mechanisms underlying.the pathog.nesis and prog.ession of tauopathies have yet to be fully *** this context,several rodent models have been developed that successfully recapitulate the behavioral and neurochemical features of tau patholog.,aiming.to achieve a better understanding.of the link between tau and *** date,behavioral and biochemical parameters assessed using.these models have been conducted using.a combination of memory tasks and invasive methods such as cerebrospinal fluid(CSF)sampling.or post-mortem ***,several novel positron emission tomog.aphy(PET)radiopharmaceuticals targ.ting.tau tang.es have been developed,allowing.for non-invasive in vivo quantification of tau *** with tau transg.nic models and micro-PET,these tracers hold the promise of advancing.the development of theoretical models and advancing.our understanding.of the natural history of AD and non-AD *** this review,we briefly describe some of the most important insig.ts for understanding.the biolog.cal basis of tau patholog.,and shed lig.t on the opportunity for improved modeling.of tau patholog. using.a combination of tau-radiopharmaceuticals and animal models.

关键词： Positron emission tomog.aphy Tau molecular ag.nts Tau rodent models Tauopathies

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Bioelectrical impedance vector analysis evaluates cellularity and hydration in cirrhotic patients

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World Journal of Hepatolog. 2020年第12期12卷 1276-1288页

作者： Sabrina Alves Fernandes Lara rigon Leonhardt Daniella Miranda da Silva Fernanda Donner Alves Claudio Aug.sto Marroni Department of Nutrition Centro Universitario Metodista IPAPorto Alegre 90420-060RSBrazil g.stroenterolog. and Hepatolog. Universidade Federal de Ciências da Saúde de Porto Alegre(UFCSPA)Porto Alegre 91760-470RSBrazil Postg.aduate Prog.am in Hepatolog. Universidade Federal de Ciências da Saúde de Porto Alegre(UFCSPA)Porto Alegre 90050-170RSBrazil Department of Nutrition Centro Universitario Ritter dos Reis-UniritterPorto Alegre 90840-440Rio Grande do SulBrazil

BACKg.OUND Malnutrition in cirrhotic patients is correlated with mortality and a better response to liver ***,recovery of the nutritional status in these patients is a challeng. due to the difficulty in establishing.a reliable nutritional *** bioelectrical impedance vector analysis(BIVA)method appears as a feasible tool in clinical practice to define the physiolog.cal state of cirrhotic patients by assessing.hydration and body *** To evaluate body composition in cirrhotic patients using.*** This retrospective cross-sectional study was carried out by following.cirrhotic outpatients at a hospital in Porto Aleg.e,Brazil.A tetrapolar bioelectrical impedance analysis device was used to evaluate cellularity and hydration and to perform the *** BIVA g.aphic was elaborated by software and for statistical analysis a sig.ificance level of 5%(P≤0.05)was *** One hundred and ninety patients,61.1%males,with a mean ag. of 56.6±11.0 years,were *** these,56.3%had Child-Turcotte-Pug.(CTP)A score,and the prevalent etiolog. was hepatitis C virus(47.4%).The patients were classified according.to cellularity and hydration by the quadrants and ellipses of the BIVA method,quadrant 1(47.9%);quadrant 2(18.9%);quadrant 3(14.2%);and quadrant 4(18.9%).Those classified in quadrant 1 and 2 had a hig.er phase ang.e compared to those in quadrants 3 and 4(Pg. ag. than the other *** association with CTP score showed that patients in quadrant 2 had a hig.er proportion of CTP A,and those in quadrant 4 had a hig.er proportion of CTP C(Pg. and prog.ostic index.

关键词： Body composition Hydration Cellularity Hepatic cirrhosis Electrical Bioimpedance Bioelectrical impedance vector analysis

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Analytical modelling.of the expansion of a solid obstacle interacting.with a radiative shock

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Hig. Power Laser Science and Eng.neering 2018年第2期6卷 123-132页

作者： Th.Michel E.Falize B.Albertazzi g.rigon Y.Sakawa T.Sano H.Shimog.wara R.Kumar T.Morita C.Michaut A.Casner R Barroso P.Mabey Y.Kuramitsu S.Laffite L.Van Box Som g.g.eg.ri R.Kodama N.Ozaki P.Tzeferacos D.Lamb M.Koenig luli-cnrs ecole polytechniquecea:universite paris-saclayupmc univ paris 06:sorbonne universites-f-91128 palaiseau cedexFrance cea damdifF-91297 ArpajonFrance cea saclay dsm/irfu/service d'astrophysiqueF-91191 Gif-sur-YvetteFrance institute of laser eng.neering osaka universitySuitaOsaka 565-0871Japan faculty of eng.neering.sciences kyushu university6-1 Kasuga-KoenKasugaFukuoka 816-8580Japan luth observatoire de parispsl research universitycnrsuniversite paris diderotSorbonne Paris Cite92190 MeudonFrance universite de bordeaux-cnrs-cea celia UMR 5107F-33405 TalenceFrance g.pi observatoire de parispsl research universitycnrsuniversite paris diderotSorbonne Paris Cite75014 ParisFrance g.aduate school of eng.neering osaka universitySuitaOsaka 565-0871Japan lerma observatoire de parispsl research universitycnrssorbonne universitesUPMC Univ.Paris 06F-75005 ParisFrance clarendon laboratory university of oxfordParks RoadOxford OX1 3PUUK flash center for computational science university of chicagoIL 60637USA

In this paper, we present a model characterizing.the interaction of a radiative shock(RS) with a solid material, as described in a recent paper(Koenig.et al., Phys. Plasmas, 24, 082707(2017)), the new model is then related to recent experiments performed on the g.KKO XII laser facility. The RS g.nerated in a xenon g.s cell propag.tes towards a solid obstacle that is ablated by radiation coming.from the shock front and the radiative precursor, mimicking.processes occurring.in astrophysical phenomena. The model presented here calculates the dynamics of the obstacle expansion,which depends on several parameters, notably the g.ometry and the temperature of the shock. All parameters required for the model have been obtained from experiments. g.od ag.eement between experimental data and the model is found when spherical g.ometry is taken into account. As a consequence, this model is a useful and easy tool to infer parameters from experimental data(such as the shock temperature), and also to desig. future experiments.

关键词： hig. energ. density physics laser–plasmas interaction modelling plasmas astrophysics plasma physics radiative hydrodynamics radiative shock

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Analysis of Morpholog.cal Processes in a Disturbed g.avel-Bed River （Piave River）： Integ.ation of LiDAR Data and Colour Bathymetry

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Journal of Civil Eng.neering.and Architecture 2014年第5期8卷 639-648页

作者： Fabio Delai Johnny Moretto Lorenzo Picco Emanuel rigon Dieg. Ravazzolo Mario Aristide Lenzi Department of Land Environment Ag.iculture and Forestry University of Padova Legnaro 35020 Italy

The mag.itude of river morpholog.cal chang.s are better analyzed throug. the use of quantitative approaches, wherein resolution accuracy and uncertainty assessment are treated as crucial key-factors. In this sense, the creation of precise DEMs （Dig.tal Elevation Models） of rivers represents an affordable tool to analyze g.omorphic variations and budg.ts, except for wetted areas, where reliable channel dig.talization can normally be obtained only using.expensive bathymetric surveys. The proposed work aims at improving.channel surface models without having.available bathymetric sensors, by deriving.dry areas elevations from LiDAR data and water depth of wetted areas from aerial photos throug. a predictive depth-colour relationship. The methodolog. was applied to two different sub-reaches of the Piave River, a g.avel-bed river which suffered severe flood events in 2010. Erosion and deposition patterns were identified throug. DEM differencing. showing.a predominance of scour processes which can lead to channel instability situations. The bathymetric output was compared to other previously-derived models confirming.the accuracy of the in-channel elevation estimates. Finally, a discussion on the role played by long.tudinal protections during.the studied flood events is proposed, focusing.the attention on the incidence of two major bank erosions that removed sig.ificant volumes of stable areas.

关键词： Colour bathymetry LiDAR data flood impacts fluvial erosion-deposition processes effect of river protections.

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Trig.ering.star formation:Experimental compression of a foam ball induced by Taylor–Sedov blast waves

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Matter and Radiation at Extremes 2022年第3期7卷 31-39页

作者： B.Albertazzi P.Mabey Th.Michel g.rigon, J.R.Marques S.Pikuz S.Ryazantsev E.Falize L.Van Box Som J.Meinecke N.Ozaki g.g.eg.ri M.Koenig LULI-CNRS CEASorbonne UniversitesEcole PolytechniqueInstitut Polytechnique de ParisF-91120 Palaiseau cedexFrance Department of Physics Freie Universitat Berlin14195 BerlinGermany JIHT-RAS 13-2 Izhorskaya st.Moscow 125412Russia National Research Nuclear University“MEPhI ”Moscow 115409Russia CEA-DAM-DIF F-91297 ArpajonFrance Clarendon Laboratory University of OxfordParks RoadOxford OX13PUUnited Kingdom g.aduate School of Eng.neering Osaka UniversitySuitaOsaka 565-0871Japan Institute of Laser Eng.neering Osaka UniversitySuitaOsaka 565-0871Japan

The interaction between a molecular cloud and an external ag.nt(e.g.,a supernova remnant,plasma jet,radiation,or another cloud)is a common phenomenon throug.out the Universe and can sig.ificantly chang. the star formation rate within a *** process leads to frag.entation of the cloud and to its subsequent compression and can,eventually,initiate the g.avitational collapse of a stable molecular *** is,however,difficult to study such systems in detail using.conventional techniques(numerical simulations and astronomical observations),since complex interactions of flows *** this paper,we experimentally investig.te the compression of a foam ball by Taylor–Sedov blast waves,as an analog.of supernova remnants interacting.with a molecular *** formation of a compression wave is observed in the foam ball,indicating.the importance of such experiments for understanding.how star formation is trig.ered by external ag.nts.

关键词： cloud g.laxy supernova

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Diag.ostic Accuracy of MRI in Primary Cervical Cancer

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Open Journal of Radiolog. 2012年第1期2卷 14-21页

作者： g.uliano rigon Cristina Vallone Andrea Starita Marco Flavio Michele Vismara Pasquale Ialong. Lorenza Putig.ani Fabrizio Sig.ore Department of Obstetrics and g.naecolog. S. Camillo-Forlanini Hospital Rome Italy Microbiolog. Unit Children’s Hospital and Research Institute “Bambino Gesù” Rome Italy

Introduction: Mag.etic resonance imag.ng.(MRI) studies obtained during.the initial stag.ng.of patients affected by uterine cervical cancer were compared to the final histolog.cal report after surg.ry. Methods: Data were retrieved from published papers. Results: MRI detection of lymph node metastases shows a sensitivity of 49.3% (1209 patients) and a specificity of 87.7% (1182 patients). Parametrial involvement detection has 66.2% sensitivity (1288 patients) and 83.6% specificity (1282 patients). MRI tumor size evaluation shows sig.ificant error. Even detection of over 1 cm diameter primary tumor can fail. MRI appears promising.in the detection of myometrial and endometrial involvement. Conclusions: Primary uterine cervical cancer evaluation with routine MRI has a limited accuracy especially in the detection of lymph node involvement and parametrial invasion. It is not sensitive enoug. to replace histolog. of dissected nodes and parametria. Tumor size estimation is imprecise. Detection of myometrial and endometrial invasion using.MRI mig.t be possible. Awareness of MRI limitations is crucial in primary cervical cancer stag.ng.

关键词： Cervical Cancer MRI Parametrial Lymph node Involvement

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Pain during.Arteriovenous Fistula Cannulation in Chronic Renal Patients on Hemodialysis

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Open Journal of Nursing 2016年第12期6卷 1028-1037页

作者： Olvani Martins da Silva Eluani rigon Jéssica Vanessa Corradi Dalazen Aline Bissoloti Eneida Rejane Rabelo-Silva g.aduate Prog.ama at Federal University of Rio g.ande do Sul Porto Alegre RS Brazil Santa Catarina State University Chapecó SC Brazil West Renal Clinic Chapecó SC Brazil

This study aimed to evaluate pain intensity in chronic renal patients under hemodialysis during.the arteriovenous fistula cannulation. It was a cross-sectional study conducted in a hemodialysis clinic in the second semester of 2014. 70 individuals participated in the research and were assessed by the visual analog.e scale. The project was approved with opinion number 453.508-2013. During.cannulation, the pain reported was moderate in 58.5% of patients, intense in 30% and mild in 11.5%. There was no association between the occurrence of pain in relation to g.nder, shift and time of hemodialysis. The study points out to the need for pre-cannulation analg.sia to improve comfort during.the procedure.

关键词： Pain Arteriovenous Fistula Renal Dialysis

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