Diagnostic Accuracy of MRI in Primary Cervical Cancer

作     者：Giuliano Rigon Cristina Vallone Andrea Starita Marco Flavio Michele Vismara Pasquale Ialongo Lorenza Putignani Fabrizio Signore 

作者机构：Department of Obstetrics and Gynaecology S. Camillo-Forlanini Hospital Rome Italy Microbiology Unit Children’s Hospital and Research Institute “Bambino Gesù” Rome Italy 

出 版 物：《Open Journal of Radiology》 (放射学期刊（英文）)

年 卷 期：2012年第2卷第1期

页      面：14-21页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Cervical Cancer MRI Parametrial Lymph node Involvement 

摘      要：Introduction: Magnetic resonance imaging (MRI) studies obtained during the initial staging of patients affected by uterine cervical cancer were compared to the final histological report after surgery. Methods: Data were retrieved from published papers. Results: MRI detection of lymph node metastases shows a sensitivity of 49.3% (1209 patients) and a specificity of 87.7% (1182 patients). Parametrial involvement detection has 66.2% sensitivity (1288 patients) and 83.6% specificity (1282 patients). MRI tumor size evaluation shows significant error. Even detection of over 1 cm diameter primary tumor can fail. MRI appears promising in the detection of myometrial and endometrial involvement. Conclusions: Primary uterine cervical cancer evaluation with routine MRI has a limited accuracy especially in the detection of lymph node involvement and parametrial invasion. It is not sensitive enough to replace histology of dissected nodes and parametria. Tumor size estimation is imprecise. Detection of myometrial and endometrial invasion using MRI might be possible. Awareness of MRI limitations is crucial in primary cervical cancer staging.