检索结果-南通市图书馆

Encapsulated peracetic acid as a valid broad‑spectrum antimicrobial alternative,leading to beneficial microbiota compositional changes and enhanced performance in broiler chickens

在线全文

学校读者我要写书评

暂无评论

Journal of Animal Science and Biotechnology 2023年第5期14卷 2128-2142页

作者： Salvatore galgano Leah conway Nikki dalby Adrian Fellows Jos g.MHoudijk Monogastric Science Research Centre Scotland’s Rural CollegeWest Mains RoadEdinburgh EH93JGScotlandUK Aga2tech Ltd HalifaxUK Centre for Innovation Excellence in Livestock YorkUK

Background Antimicrobial alternatives are urgently needed,including for poultry production *** this study,we tested the potential broad-range antimicrobial alternative peracetic acid,delivered in feed via the hydrolysis of encapsulated precursors through a 28-day study using 375 Ross 308 broiler *** tested two peracetic acid concentrations,30 and 80 mg/kg on birds housed on re-used litter,and we evaluated the impact of both levels on gut microbial communities,bacterial concentration,antimicrobial resistance genes relative abundance and growth performance when compared to control birds housed on either clean or re-used *** Body weight gain and feed conversion ratio improved in peracetic acid fed *** d 28,birds given 30 mg/kg of peracetic acid had a decreased Firmicutes and an increased Proteobacteria abundance in the jejunum,accompanied by an increase in Bacillus,Flavonifractor and Rombustia in the caeca,and a decreased abundance of tetracycline resistance *** given 80 mg/kg of peracetic acid had greater caecal abundance of macrolides lincosamides and streptogramins resistance *** performance on clean litter was reduced compared to reused litter,which concurred with increased caecal abundance of Blautia,decreased caecal abundance of Escherichia/Shigella,Anaerostipes and Jeotgalicoccus,and greater gene abundance of vancomycin,tetracycline,and macrolides resistance *** Peracetic acid could be used as a safe broad-spectrum antimicrobial alternative in *** precursors were able to reduce the bacterial concentration in the jejunum whilst promoting the proliferation of probiotic genera in the caeca,especially at the low peracetic acid concentrations tested,and improve growth ***,our findings offer further insights on potential benefits of rearing birds on re-used litter,suggesting that the latter could be associated with better performance and reduced antimicrobial resistance

关键词： Antimicrobial alternative Antimicrobial resistance Broiler chicken Microbiota Peracetic acid Performance 16S rRNA gene

Advanced concepts in knee arthrodesis

在线全文

学校读者我要写书评

暂无评论

World Journal of Orthopedics 2015年第2期6卷 202-210页

作者： Jennifer H Wood Janet d conway department of Orthopaedics University of Maryland School of Medicine University of Maryland Medical System International Center for Limb Lengthening Rubin Institute for Advanced OrthopedicsSinai Hospital of Baltimore

The aim is to describe advanced strategies that can beused to diagnose and treat complications after knee arthrodesis and to describe temporary knee arthrodesis to treat infected knee arthroplasty. Potential difficult complications include nonunited knee arthrodesis, limb length discrepancy after knee arthrodesis, and united but infected knee arthrodesis. If a nonunited knee arthrodesis shows evidence of implant loosening or failure, then bone grafting the nonunion site as well as exchange intramedullary nailing and/or supplemental plate fixation are recommended. If symptomatic limb length discrepancy cannot be satisfactorily treated with a shoe lift, then the patient should undergo tibial lengthening over nail with a monolateral fixator or exchange nailing with a femoral internal lengthening device. If a united knee arthrodesis is infected, the nail must be removed. Then the surgeon has the option of replacing it with a long, antibiotic cement-coated nail. The authors also describe temporary knee arthrodesis for infected knee arthroplasty in patients who have the potential to undergo insertion of a new implant. The procedure has two goals: eradication of infection and stabilization of the knee. A temporary knee fusion can be accomplished by inserting both an antibiotic cement-coated knee fusion nail and a static antibiotic cement-coated spacer. These advanced techniques can be helpful when treating difficult complications after knee arthrodesis and treating cases of infected knee arthroplasty.

关键词： Arthroplasty Knee Arthrodesis Nonunion Limb salvage Limb length inequality Infection Osteomyelitis Bone lengthening External fixator

Current state of endohepatology: diagnosis and treatment of portal hypertension and its complications with endoscopic ultrasound

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Hepatology 2021年第8期13卷 887-895页

作者： Sean R Rudnick Jason d conway Mark W Russo Section on gastroenterology&Hepatology Wake Forest School of MedicineWinston-SalemNC 27157United States department of Hepatology Atrium HealthCarolinas Medical CenterCharlotteNC 28204United States

The diagnosis and management of cirrhosis and portal hypertension(PH)with its complications including variceal hemorrhage,ascites,and hepatic encephalopathy continues to *** there are established“standards of care”in liver biopsy and measurement of PH,gastric varices remain an area without a universally accepted therapeutic *** concept of“Endo Hepatology”has been used to describe of the applications of endoscopic ultrasound(EUS)to these ***-liver biopsy(EUS-LB)offers an alternative to percutaneous and transjuglar liver biopsy without compromising safety or efficacy,and with added advantages including the potential to reduce sampling error by allowing biopsies in both hepatic ***,EUS-LB can be performed during the same procedure as EUS-guided portal pressure gradient(PPg)measurements,allowing for the collection of valuable diagnostic and prognostic ***-guided PPg measurements provide an appealing alternative to the transjugular approach,with proposed advantages including the ability to directly measure portal vein *** addition,EUS-guided treatment of gastric varices(gV)offers several possible advantages to current ***-guided treatment of gV allows detailed assessment of the vascular anatomy,similar efficacy and safety to current therapies,and allows the evaluation of treatment effect through doppler ultrasound *** appropriate selection of patients for these procedures is paramount to ensuring generation of useful clinical data and patient safety.

关键词： Portal hypertension Endoscopic ultrasound Liver biopsy gastric varices

Limb Lengthening and Reconstruction Society orthopedic surgeons in the United States:An analysis of geographical distribution,academic,leadership,and demographic characteristics

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Orthopedics 2024年第2期15卷 147-155页

作者： Amir Human Hoveidaei Reza Niakan Seyed Hossein Hosseini-Asl Abijith Annasamudram Janet d conway International Center for Limb Lengthening Rubin Institute for Advanced OrthopedicsSinai Hospital of BaltimoreBaltimoreMD 21215United States Student Research Committee Shiraz University of Medical SciencesShiraz 73Iran Students’Scientific Research Center Tehran University of Medical SciencesTehran ***Iran

BACKgROUNd The Limb Lengthening and Reconstruction Society(LLRS)is a premier orthopedic specialty organization that promotes limb reconstruction for all *** membership characteristics,however,are poorly *** study delineates orthopedic surgeon LLRS members’demographic traits,academic achievement,leadership attainment,and geographical distribution across the United *** To inform aspiring orthopedic professionals,as well as to promote growth and diversity in both the LLRS organization and overarching *** This cross-sectional study examined United States LLRS members’academic,leadership,demographic,and geographical *** reviewing the 2023 LLRS member directory,google search results were matched to the listings and appended to the compiled *** and ethnicity were evaluated visually utilizing retrieved *** Hirsch index(H-index)of academic activity,residency and fellowship training,other graduate degrees,leadership positions,practice type(academic or non-academic),and spoken languages were *** members per state and capita determined geographic *** Mann Whitney U test was applied to compare H-index between males and females,as well as to assess member differences pertaining to affiliation with academic vs non-academic practice *** The study included 101 orthopedic surgeons,78(77.23%)Caucasian and 23(22.77%)non-Caucasian,79(78.22%)male and 22(21.78%)*** with dO degrees comprised only 3.96%(4)of the cohort,while the vast majority held Mds[96.04%(97)].Mean H-index was 10.55,with male surgeons having a significantly higher score(P=0.002).Most orthopedic surgeons(88.12%,)practiced in academic *** those professionals who occupied leadership positions,14%were women,while 86%were ***,19(37.25%)United States regions and the district of Columbia lacked an LLRS-member orthopedic *** per capita rate across the United States was 0.30 LLRS orthopedic

关键词： Limb lengthening and reconstruction Orthopedic surgeon demographics Orthopedic surgeon societal membership Orthopedic fellowships

The effects of dietary supplementation with mushroom or selenium enriched mushroom powders on the growth performance and intestinal health of post-weaned pigs

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Animal Science and Biotechnology 2023年第3期14卷 1167-1181页

作者： Alison dowley Torres Sweeney Eadaoin conway Stafford Vigors Marion T.Ryan Supriya Yadav Jude Wilson John V.O’doherty School of Agriculture and Food Science University College DublinBelfieldDublin 4Ireland School of Veterinary Medicine University College DublinBelfieldDublin 4Ireland Mbio Monaghan Mushroom GroupTyhollandCo.MonaghanIreland

Background There is an urgent need to identify natural bioactive compounds that can enhance gastrointestinal health and promote pig growth performance in the absence of pharmacological levels of zinc oxide(ZnO).The objectives of this study were to:1)compare the effects of mushroom powder supplemented with inorganic selenium(inSeMP)to mushroom powder enriched with organic selenium(orgSeMP)to pharmacological levels of ZnO on growth performance and faecal scores(FS)for the first 21 d post-weaning(Period 1);and 2)compare the molecular and microbial effects of inSeMP and orgSeMP in these pigs on d 39 post-weaning(Period 2).Methods In Period 1,pigs(3 pigs/pen;8 pens/treatment)were assigned to:(1)basal diet(control);(2)basal diet+zinc oxide(ZnO)(3100 mg/kg d 1–14,1550 mg/kg d 15–21);(3)basal diet+mushroom powder supplemented with inorganic selenium(inSeMP)containing selenium(selenite)content of 0.3 mg/kg feed;(4)basal diet+mushroom powder enriched with organic selenium(orgSeMP)containing selenium(selenocysteine)content of 0.3 mg/kg *** powders were included at 6.5 g/kg of *** In Period 1,there was no effect of diets on average daily gain(Adg)and gain:feed(g:F)ratio(P>0.05).The orgSeMP supplemented pigs had a lower average daily feed intake(AdFI)compared to all other groups(Pd pigs had reduced FS compared to the basal and mushroom group,while the orgSeMP supplemented pigs had lower FS compared to the basal group during the 21 d experimental period(Pd 2,there was no effect of diets on AdFI,Adg and g:F ratio(P>0.05).The orgSeMP supplementation increased the caecal abundance of bacterial members of the Firmicutes and Bacteroidetes phylum,including Lactobacillus,Agathobacter,Roseburia,and Prevotella and decreased the abundance of Sporobacter compared to the basal group,while inSeMP increased the caecal abundance of Prevotella and decreased the caecal abundance of Sporobacter compared to the basal group(Pdietary

关键词： Agaricus bisporus gastrointestinal microbiota Mushroom powder Organic selenium Pig Zinc oxide

Urban Vulnerabilities in the Kathmandu Valley, Nepal: Visualizations of Human/Hazard Interactions

在线全文

学校读者我要写书评

暂无评论

Journal of geographic Information System 2010年第2期2卷 63-84页

作者： Keshav Bhattarai dennis conway 不详

Excessive unplanned urban growth leads to many vulnerabilities and impacts on urban environments to varying degrees. However, the majority of the extant literature focuses on the problems related to location and socioeconomic conditions, rather than vulnerability processes and related environmental degradation. This paper analyzes the scope of urban vulnerabilities for five rapidly urbanizing and highly-congested cities in the Kathmandu Valley, Nepal. First, the historic context of the Valley’s uncontrolled urbanization sets the scene. Second, the optic is narrowed to focus upon the geographical features of the resultant urbanized Valley landscape that includes spatial arrangements and of houses, population densities, road networks, vehicular densities, garbage problems, and available open spaces. Additionally, seismic vulnerabilities in the urban areas are also considering in this examination. Third, three-dimensional visualizations of selected urban locations are presented to differentiate between vulnerable and relatively safe locations. The intent of this research is to contribute to the methodological understanding of human/hazards interactions in rapidly urbanizing cities of the Third World, which share similar socioeconomic conditions and environmental con-texts.

关键词： Urban Vulnerability Planning Kathmandu Valley Two dimensional (2d) Maps Three dimensional (3d) Visualization

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

谁谋杀了上帝?

世界哲学 2019年第4期 66-81,F0003页

作者： d·康威[美] 王齐(译) 德克萨斯农工大学(Texas A & M University)哲学与人文学中国社会科学院哲学研究所

尼采通常被视为是无神论事业的哲学捍卫者,但是通过对尼采《快乐的科学》中“疯子”及其在市场中的表现的分析可以揭示出,“疯子”并不是尼采的代言人,而是对尼采学说的极具诱惑力的歪曲。“疯子”没有把“上帝死了”作为探索自我肯定... 详细信息

尼采通常被视为是无神论事业的哲学捍卫者,但是通过对尼采《快乐的科学》中“疯子”及其在市场中的表现的分析可以揭示出,“疯子”并不是尼采的代言人,而是对尼采学说的极具诱惑力的歪曲。“疯子”没有把“上帝死了”作为探索自我肯定的非关系性基础的机会,他宁愿背负杀死上帝的终极之罪,也不愿思索与上帝无关且不受罪玷污的生存可能性。因此“疯子”所宣称的“我们已经杀死上帝”的信念伪造了一种后有神论生存,但实际上,晚期现代西方人并没有做好接受彻底无神论的准备。对于尼采来说,“上帝死了”则标志着人类历史上一个黄昏时期的开端,人们对上帝的信仰变得越来越非理性和不可思议,但又不可动摇,不是因为人的选择或过失,而是因为一个濒临衰竭的文化融合的传统。

关键词：尼采无神论后有神论启蒙方案晚期现代

Retinal and Choroidal Alterations in Migraine Patients Compared to Normal Healthy Controls

在线全文

学校读者我要写书评

暂无评论

Journal of Behavioral and Brain Science 2023年第10期13卷 185-197页

作者： Miriam L. conway Irene Ctori department of Optometry and Visual Science City University of London London UK

Purpose: Migraine is an incapacitating neurovascular disorder that primarily affects the working-age population. Researchers have postulated that the transient vascular alterations during each migraine attack lead to ischemic damage in the eye which can be measured via optical coherence tomography. Methods: We recruited 29 volunteers: 13 migraineurs (mean age 28 ± 8.8 years;12 female and 1 male) and 16 age-matched controls (mean age 26.6 ± 6.9;9 female and 7 male). All individuals underwent a detailed ophthalmic examination by a qualified optometrist and a Migraine disability Assessment. The investigators were blind to the migraine diagnosis. Retinal Nerve Fiber Layer (RNFL) thickness, Retinal Thickness (RT), ganglion Cell Complex (gCL), ranging from the inner-limiting membrane to the inner plexiform layer, and Choroidal Thickness (CT) were measured using the 3d OCT-1Maestro, Topcon, a Spectral domain OCT (Sd-OCT) device. Results: In the migraine population average RNFL was lower for several parameters. However, results did not reach statistical significance. A significant decrease in the right eye inferior parafoveal ganglion cell layer in the migraine group of patients (mean = 25.15, Sd = 4.08) compared to normal healthy controls (mean = 28.81, Sd = 4.85;t = (27) = 2.17, p = 0.039) was documented. No other ganglion cell layer or choroidal thickness reached significance. No significant relationship between ocular thickness parameters and MIdAS score, parameters and either MIdAS score or frequency of headaches was found. Conclusion: A significant decrease in the right inferior parafoveal ganglion cell layer for migraine patients was reported. All other parameters did not reach significance. .

关键词： Retinal Choroidal Migraine

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欧洲的近实时降水分析

气象科技 1992年第4期20卷 75-79页

作者： d.M.goddard B.J.conway 王亚光英国气象局

1.前言1986年4月26日,苏联乌克兰切尔诺贝利列宁核电站4号反应堆发生事故.该事故在世界上是迄今为止最为严重的逸出放射性物质进入大气的事件,逸出的大量物质从空中被输送到遥远的地区,造成对欧洲许多地区的污染(Smith和Clark,1989).

关键词：欧洲降水地面污染物沉降模式