Current state of endohepatology: Diagnosis and treatment of portal hypertension and its complications with endoscopic ultrasound

作     者：Sean R Rudnick Jason D Conway Mark W Russo 

作者机构：Section on Gastroenterology&HepatologyWake Forest School of MedicineWinston-SalemNC 27157United States Department of HepatologyAtrium HealthCarolinas Medical CenterCharlotteNC 28204United States 

出 版 物：《World Journal of Hepatology》 (世界肝病学杂志（英文版）（电子版）)

年 卷 期：2021年第13卷第8期

页      面：887-895页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：Cook Medical Endoscopy 

主　　题：Portal hypertension Endoscopic ultrasound Liver biopsy Gastric varices 

摘      要：The diagnosis and management of cirrhosis and portal hypertension(PH)with its complications including variceal hemorrhage,ascites,and hepatic encephalopathy continues to *** there are established“standards of carein liver biopsy and measurement of PH,gastric varices remain an area without a universally accepted therapeutic *** concept of“Endo Hepatologyhas been used to describe of the applications of endoscopic ultrasound(EUS)to these ***-liver biopsy(EUS-LB)offers an alternative to percutaneous and transjuglar liver biopsy without compromising safety or efficacy,and with added advantages including the potential to reduce sampling error by allowing biopsies in both hepatic ***,EUS-LB can be performed during the same procedure as EUS-guided portal pressure gradient(PPG)measurements,allowing for the collection of valuable diagnostic and prognostic ***-guided PPG measurements provide an appealing alternative to the transjugular approach,with proposed advantages including the ability to directly measure portal vein *** addition,EUS-guided treatment of gastric varices(GV)offers several possible advantages to current ***-guided treatment of GV allows detailed assessment of the vascular anatomy,similar efficacy and safety to current therapies,and allows the evaluation of treatment effect through doppler ultrasound *** appropriate selection of patients for these procedures is paramount to ensuring generation of useful clinical data and patient safety.