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A PRECONDITIONER FOR DOMAIN DECOMPOSITION METHODS WITH MORTAR LAGRANGE MULTIPLIERS

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Journal of Systems Science & Complexity 2002年第4期15卷 384-395页

作者： hu Qiyia College of

In this paper we consider the domain decomposition methods with mortar element Lagrange multipliers to two-dimensional elliptic *** shall construct a kind of simple preconditioners for the corresponding interface *** ... 详细信息

关键词： Domain decomposition non-matching grids Lagrange multipliers precon-ditioner condition number.

Beta-adrenergic agonist protects retinal pigment epithelium against hydroxycholoroquine toxicity via c AMP-PKA signal pathway

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International Journal of Ophthalmology(English edition) 2020年第4期13卷 552-559页

作者： Ruihua Zhang Dan-Ning hu Richard Rosen Eye and Vision Research Institute Department of OphthalmologyIcahn School of Medicine at Mount SinaiNew York 10029USA Department of Ophthalmology New York Eye and Ear Infirmary of Mount SinaiNew York 10003USA

AIM: To test our hypothesis that activation of protein kinase A(PKA) signal pathway by β-adrenergic agonist plays an important role in the protecting of cultured retinal pigment epithelial(RPE) cells against the hydroxychloroquine(HCQ) toxicity. METHODS: Cultured human RPE cells were treated with 1) HCQ, 2) HCQ with salbutamol(a β2-adrenergic receptor agonist), and 3) HCQ with salbutamol and a PKA inhibitor, and compared these to 4) untreated cells(controls). After treated for 24 h, cell vacuolation, cells viability, PKA and PKA kinase activity levels were determined by the measurement of the size of vacuoles using Image J software, the cell counting with a dye-exclusion testing, Western blot and PKA kinase detection, respectively. RESULTS: Cell vacuolation and cell death of cultured RPE cells were significantly increased by the treatment of HCQ. Salbutamol significantly elevated PKA and PKA activity levels and this was associated with the inhibition of the vacuolation and cell death. The PKA inhibitor significantly decreased the PKA levels and eliminated the protective effects of salbutamol on HCQ-treated RPE cells. CONCLUSION: The PKA pathway plays an important role in the protective effects of β2-adrenergic agonist on the RPE cells against HCQ toxicity. These findings reveal a novel potential strategy against HCQ retinopathy by treatment with PKA activating medications.

关键词： hydroxycholoroquine retinal pigment epithelial cells retinopathy protein kinase A vacuolation

Genomic analysis of sugar transporter genes in peanut (Arachis hypogaea):Characteristic,evolution and expression profiles during development and stress

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Oil Crop Science 2022年第4期7卷 189-199页

作者： Zhijun Xu Lei Xu Xiaowen hu Guangdong Engineering Technology Research Center for Dryland Water-saving Agriculture Zhanjiang Experiment StationChinese Academy of Tropical Agricultural SciencesZhanjiangGuangdongChina Zhanjiang Experimental and Observation Station for National Long-term Agricultural Green Development ZhanjiangGuangdongChina

Peanut(Arachis hypogaea L.) is an economically significant crop with aerial cleistogamous flowers and subterranean geocarpic fruit(pods).The formation of peanut pod requires movement of the embryo from air to ground and then development in the soil,which is a complex biological process involving transport and accumulation of *** transport proteins(STP) mediate the transport of monosaccharides in various physiological processes,including fertilization,ovary formation,and seed *** this study,a total of 36 AhSTP genes(AhSTP1–36) containing the conserved sugar_tr motif were identified in the *** *** analysis revealed that AhSTP genes were classified into four clades,and the arrangement of motifs in AhSTP proteins was similar within *** analysis revealed that segmental duplication events have played an important role in the expansion of STP genes in peanut,and chromosome rearrangements might have facilitated the exchange of STP genes between the A and B *** analyses revealed that the expression patterns of AhSTP genes varied among *** and abiotic stress treatments could upregulate or down-regulate the expression of AhSTP genes,and low temperature had a major effect on the expression of most AhSTP *** AhSTP genes(AhSTP3,AhSTP9,AhSTP19,and AhSTP28) were specifically expressed in the pod,indicating that these genes might be involved in pod formation and development in *** unique expression of these four genes during pod construction and development was confirmed in two different type cultivars using quantitative real-time PCR *** findings provide new insights into the STP gene family in peanut and will aid future functional studies of AhSTP genes.

关键词： Peanut STP gene Family Evolution Expression patterns Pod development

Synthesis and Herbicidal Activity of 5-Heterocycloxy-3-substituted-1-(3-trifluoromethyl)phenyl-1H-pyrazole

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Chemical Research in Chinese Universities 2012年第5期28卷 824-827页

作者： XU Han hu Xu-hong ZOU Xiao-mao Zhu You-quan LIU Bin hu Fang-zhong YANG hua-zheng National Engineering Research Center of Pesticide(Tianjin) State Key Laboratory of Elemento-Organic Chemistry Elemento-Organic Chemistry InstituteNankai UniversityTianjin 300071P.R.China

The authors synthesized a series of novel 5-heterocycloxy-3-substituted-1-（3-trifluoromethyl）phenyl-1H- pyrazole derivatives. Herbicidal activities of the two intermediate compounds and thirteen target compounds were evaluated via Brassica napus and Echinochloa crusgalli（L.） Beauv tests. Bioassay results show that some of the compounds exhibit better inhibiting activities against Brassica napus and some of the compounds exhibit bleaching activities against Echinochloa crusgalli（L.） Beauv at 100 μg/mL.

关键词： 1-(3-Trifluoromethyl)phenyl-1H-pyrazole Herbicide Inhibition

Multi-sensor federated unscented Kalman filtering algorithm in intermittent observations

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High Technology Letters 2015年第2期21卷 132-139页

作者：胡振涛 hu Yumei Li Song Institute of Image Processing and Pattern Recognition Henan University College of Computer and Information Engineering Henan University

Aiming at the adverse effect caused by limited detecting probability of sensors on filtering preci- sion of a nonlinear system state, a novel muhi-sensor federated unscented Kalman filtering algorithm is proposed. Firstly, combined with the residual detection strategy, effective observations are cor- rectly identified. Secondly, according to the missing characteristic of observations and the structural feature of unscented Kalman filter, the iterative process of the single-sensor unscented Kalman filter in intermittent observations is given. The key idea is that the state estimation and its error covariance matrix are replaced by the state one-step prediction and its error covariance matrix, when the phe- nomenon of observations missing occurs. Finally, based on the realization mechanism of federated filter, a new fusion framework of state estimation from each local node is designed. And the filtering precision of system state is improved further by the effective management of observations missing and the rational utilization of redundancy and complementary information among multi-sensor observa- tions. The theory analysis and simulation results show the feasibility and effectiveness of the pro- posed algorithm.

关键词： nonlinear estimation intermittent observations unscented Kalman filter federated filter

Blockchain or Not?Optimal Decisions for Food Retailers Considering Consumer Expertise

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Journal of Systems Science and Information 2021年第3期9卷 321-334页

作者： Linyuan hu Jinzhi DING Xiying YANG School of Economics and Management Beijing Jiao tong UniversityBeijing 100044China

This paper studies the benefit of the blockchain food traceability system(BFTS).Based on game theory and the willingness-to-pay model,pricing models are formulated considering important factors like the proportion of consumer with high expertise in traceability,risk attitude to doubtful traceability information and perceived convenience of traceability information *** compared the optimal total welfare under the BFTS and that under the traditional food traceability system in valuation analysis,conditions where applying the BFTS is more valuable than applying the TFTS are figured ***,insightful management implications are given.

关键词： the blockchain food traceability system consumer expertise pricing valuation analysis

Cobalt(I) Catalyzed Reaction of Benzaldehydes with Functionalized Benzylic Zinc Halides

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Chinese Chemical Letters 2002年第5期13卷 405-406页

作者： Jin Xian WANG Ying FU Yu Lai hu College of Chemistry&Chemical Engineering Northwest Normal UniversityLanzhou 730070

Functionalized benzylic zinc halides reacted with benzaldehydes in the presence of Lewis acid Me3SiCl giving high yields of trans-stilbenes under the catalysis of Co(PPh3)3Cl.

关键词： Co(I) catalysis functionalized benzylic zinc halides benzaldehydes stilbenes.

Design of elliptical underwater acoustic cloak with truss-latticed pentamode materials

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Theoretical & Applied Mechanics Letters 2022年第4期12卷 221-226页

作者： Yuanyuan Ge Xiaoning Liu Gengkai hu School of Aerospace Engineering Beijing Institute of TechnologyBeijing 100081China

Pentamode acoustic cloak is promising for underwater sound control due to its solid nature and broadband efficiency,however its realization is only limited to simple cylindrical *** this work,we established a set of techniques for the microstructure design of elliptical pentamode acoustic cloak based on truss lattice model,including the inverse design of unit cell and algorithms for latticed cloak *** designed cloak was numerically validated by the well wave concealing *** work proves that more general pentamode acoustic wave devices beyond simple cylindrical geometry are theoretically feasible,and sheds light on more practical design for waterborne sound manipulation.

关键词： Elliptical acoustic cloak Pentamode material Microstructure design Truss lattice

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网络问卷调查的数据质量控制研究

统计与决策 2019年第16期35卷 10-14页

作者：余富强胡鹏辉杜沙沙南京大学社会学院

为了提高网络问卷的调查质量,需要控制网络问卷的各个阶段。文章探讨了网络问卷调查各个阶段数据质量控制的措施。在问卷设计阶段,优化网络问卷以适应移动智能终端,并充分利用网络问卷系统的样本监测、自动跳转、数据检测等技术优势;在... 详细信息

为了提高网络问卷的调查质量,需要控制网络问卷的各个阶段。文章探讨了网络问卷调查各个阶段数据质量控制的措施。在问卷设计阶段,优化网络问卷以适应移动智能终端,并充分利用网络问卷系统的样本监测、自动跳转、数据检测等技术优势;在抽样阶段,针对网络问卷多用于非概率抽样研究这一事实,采用被访者驱动等可实现统计推论的方法,提升抽样的科学性;在数据收集阶段,增强对于社交平台用户邀请方式、电子红包等激励方式的控制,实现对于网络问卷扩散及填答方式的掌控;在资料处理阶段,需要根据网络问卷的内部和外部特征进行在线即时审核,并利用特定统计技术实现数据清洗。

关键词：网络问卷数据质量被访者驱动抽样在线即时审核