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Numerical Solutions to the Robin Inverse Problem with Nonnegativity Constraints

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Journal of Applied Mathematics and Physics 2022年第6期10卷 2015-2025页

作者： Weifu Fang fu-rong lin Department of Mathematics and Statistics Wright State University Dayton USA Department of Mathematics Shantou University Shantou China

We present iterative numerical methods for solving the inverse problem of recovering the nonnegative Robin coefficient from partial boundary measurement of the solution to the Laplace equation. Based on the boundary integral equation formulation of the problem, nonnegativity constraints in the form of a penalty term are incorporated conveniently into least-squares iteration schemes for solving the inverse problem. Numerical implementation and examples are presented to illustrate the effectiveness of this strategy in improving recovery results.

关键词： Robin Inverse Problem Ill-Posed Problem Laplace Equation Boundary Inte-gral Equation Nonnegativity Constraint Penalty Method

Dynamic color-tunable ultra-long room temperature phosphorescence polymers with photo-chromism and water-stimuli response for multilevel anti-counterfeiting

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Aggregate 2024年第5期5卷 320-330页

作者： Xiao Ma Tian-Jiao Ye Han-Jiang Yang Guang-Kun ling Danfeng Wang Jia-Shu Li Peiyang Gu Liang-Jin Xu Tian-Lu Sheng fu-rong lin Run-fu Shen Qichun Zhang Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology Advanced Catalysis and Green Manufacturing Collaborative Innovation CenterSchool of Petrochemical EngineeringChangzhou UniversityChangzhouJiangsuChina Department State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of Matter Chinese Academy of ScienceFuzhouFujianChina Zhejiang Engineering Research Center of Fat-soluble Vitamin Shaoxing UniversityShaoxingZhejiangChina Department of Materials Science and Engineering Department of ChemistryCenter of Super-Diamond and Advanced Films(COSDAF)and Hong Kong Institute of Clean EnergyCity University of Hong KongHong KongChina

Developing dynamic color-tunable ultra-long room temperature phosphorescence(URTP)polymers with afterglow of over 1 s,photo-chromism,and multi-stimuli response for practical anti-counterfeiting and information security applications is attractive but very ***,by doping multicolor phosphorescence pyri-dinium bromide L block or viologen-based photo-chromic V block into polyvinyl alcohol matrixes,the water-stimuli-responsive color-tunable URTP polymerﬁlms with afterglow of up to 8 s and the reversible viologen-based photochromic polymerﬁlms have been *** signiﬁcantly,a series of dynamic color-tunable URTP polymerﬁlms with ultra-long afterglow of over 6 s,photo-chromism,and water-stimuli response have been successfully exploited by integrating L and V blocks into one polymer *** investigations have revealed that their photo-chromism mainly comes from the photo-generated viologen free ***,their dynamic multilevel anti-counterfeiting applications have been *** results pave the way to develop smarter multifunctional URTP materials for anti-counterfeiting and optical sensing.

关键词： anti-counterfeiting phosphorescence photochromism stimuli response ultralong viologen

新安江流域生态系统服务福祉效应及实现路径研究——基于798份乡村居民问卷调查的实证分析

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长江流域资源与环境 2023年第10期32卷 2109-2123页

作者：符琳蓉任以胜陆林李天宇华东师范大学地理科学学院上海200241 安徽师范大学地理与旅游学院安徽芜湖241002 安徽师范大学经济管理学院安徽芜湖241002 安徽师范大学乡村振兴研究院安徽芜湖241002

乡村居民从流域生态系统中受益是自然、社会、经济系统相互作用的结果。基于798份新安江流域乡村居民的问卷调查,结合计划行为理论构建了流域生态系统服务福祉效应及实现路径的逻辑框架,从流域生态系统服务重要性和居民福祉满意度分析... 详细信息

乡村居民从流域生态系统中受益是自然、社会、经济系统相互作用的结果。基于798份新安江流域乡村居民的问卷调查,结合计划行为理论构建了流域生态系统服务福祉效应及实现路径的逻辑框架,从流域生态系统服务重要性和居民福祉满意度分析了流域居民的需求和需求满足状况,并运用结构方程模型探讨了自然生态系统流向福祉的具体过程。结果表明:(1)流域乡村居民以纯农户为主,生计方式对供给服务与调节服务需求较高,因此重要性认知较高,流域生态系统服务变化总体呈略微上升趋势;(2)居民健康福祉满意度较高,自由和选择福祉满意度较低,高阶福祉需求满足状况欠佳且较难实现;(3)福祉实现是居民作为行动主体发挥主观能动性、促进自然生态系统和社会经济系统形成良性互动反馈的结果。总结出2条实现路径:(1)生态系统服务重要性→生态认知→生态系统服务变化→居民福祉;(2)生态系统服务重要性→生态认知→参与意愿→生态环境行为→生态系统服务变化→居民福祉。文末从居民生态认知提高、可持续生计转型升级、奖惩措施制定、行动主体主观能动性发挥等方面提出了促进福祉实现的建议。

关键词：生态系统服务福祉效应实现路径乡村居民新安江流域

基于参数修正的安徽省生态承载力演化特征及影响因素

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长江流域资源与环境 2021年第10期30卷 2438-2451页

作者：符琳蓉王咏陆林任以胜张潇李冬花安徽师范大学地理与旅游学院安徽芜湖241002 安徽师范大学经济管理学院安徽芜湖241002

生态承载力状况是新时代生态文明建设研究的着眼点,也是科学把控人与自然和谐发展的关键。以安徽省16个地级市为研究单元,利用参数修正后的生态承载力模型测算安徽省及各城市整体与人均层面上的生态承载力,运用数理统计分析比较1998~201... 详细信息

生态承载力状况是新时代生态文明建设研究的着眼点,也是科学把控人与自然和谐发展的关键。以安徽省16个地级市为研究单元,利用参数修正后的生态承载力模型测算安徽省及各城市整体与人均层面上的生态承载力,运用数理统计分析比较1998~2018年安徽省生态承载力的演化特征,并结合地理探测器探究各因素对安徽省生态承载力影响力的变化。结果表明:(1)基于"省公顷"进行修正后的模型参数与其他尺度显著不同,差异明显;(2)全省生态承载力总体呈上升趋势,全省人均生态承载力呈现显著下降趋势。各市生态承载力自身波动变化趋势显著,与其他城市存在差距;各市的人均生态承载力两极分化现象突出,升降趋势与整体层面不同;(3)各市生态承载力存在一定退化现象,皖北地区状况较皖南地区优势突出,"南低北高"的空间格局特征鲜明;(4)影响因素中环境治理能力、经济发展方式、社会发展水平等影响因素作用在增强,人口压力状况作用削弱,双因子交互作用的影响力要大于单因子作用。需要持续关注生态承载力的演化特征,合理优化生态承载力区,保证社会经济发展与其资源本底供给相适应。

关键词：参数修正生态承载力演化特征地理探测器安徽省

Bidirectional regulation of the brain-gut-microbiota axis following traumatic brain injury

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Neural Regeneration Research 2025年第8期20卷 2153-2168页

作者： Xinyu You lin Niu Jiafeng fu Shining Ge Jiangwei Shi Yanjun Zhang Pengwei Zhuang National Key Laboratory of Chinese Medicine Modernization Tianjin University of Traditional Chinese MedicineTianjinChina Haihe Laboratory of Modern Chinese Medicine Tianjin University of Traditional Chinese MedicineTianjinChina First Teaching Hospital of Tianjin University of Traditional Chinese Medicine TianjinChina National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion TianjinChina

Traumatic brain injury is a prevalent disorder of the central nervous *** addition to primary brain parenchymal damage,the enduring biological consequences of traumatic brain injury pose long-term risks for patients with traumatic brain injury;however,the underlying pathogenesis remains unclear,and effective intervention methods are *** dysfunction is a significant consequence of traumatic brain *** the most densely innervated peripheral tissue in the body,the gut possesses multiple pathways for the establishment of a bidirectional“brain-gut axis”with the central nervous *** gut harbors a vast microbial community,and alterations of the gut niche contribute to the progression of traumatic brain injury and its unfavorable prognosis through neuronal,hormonal,and immune pathways.A comprehensive understanding of microbiota-mediated peripheral neuroimmunomodulation mechanisms is needed to enhance treatment strategies for traumatic brain injury and its associated *** comprehensively reviewed alterations in the gut microecological environment following traumatic brain injury,with a specific focus on the complex biological processes of peripheral nerves,immunity,and microbes triggered by traumatic brain injury,encompassing autonomic dysfunction,neuroendocrine disturbances,peripheral immunosuppression,increased intestinal barrier permeability,compromised responses of sensory nerves to microorganisms,and potential effector nuclei in the central nervous system influenced by gut ***,we reviewed the mechanisms underlying secondary biological injury and the dynamic pathological responses that occur following injury to enhance our current understanding of how peripheral pathways impact the outcome of patients with traumatic brain *** review aimed to propose a conceptual model for future risk assessment of central nervous system-related diseases while elucidating novel insights into the bidirectional effec

关键词： traumatic brain injury brain-gut-microbiome axis gut microbiota neuroimmune immunosuppression host defense vagal afferents bacterial infection dorsal root ganglia nociception neural circuitry

Surfing the nano-wave:Emerging trends in cancer diagnostics and therapy

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Nano Research 2025年第1期18卷 520-544页

作者： Genping fu Yuting Weng Yunfan Li Carl Ho Yiyu fu Wenxuan Wang Songbin fu Wenjing Sun Jie lin Xiaoyu Fan Binbin Jia Mengdi Cai linlin Li Laboratory of Medical Genetics Harbin Medical UniversityHarbin 150081China Key Laboratory of Preservation of Human Genetics Resources and Disease Control in China(Harbin Medical University) Ministry of EducationHarbin 150081China Beijing Key Laboratory for Optical Materials and Photonic Devices Department of ChemistryCapital Normal UniversityBeijing 100048China College of Materials and Chemical Engineering Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion MaterialsChina Three Gorges UniversityYichang 443002China Washington University School of Medicine in St.Louis St.LouisMO 63110USA Ningbo Institute of Materials Technology and Engineering Chinese Academy of SciencesNingbo 315201China Aix-Marseille College Wuhan University of TechnologyWuhan 430070China

Facing the growing global challenge posed by cancer,the quest for more accurate and potent cancer diagnostic and therapeutic strategies continues to require a multidisciplinary integration *** review firstly summarizes various types of nanoparticles in cancer ***,it offers a comprehensive overview of signalenhancing techniques for visualizing in situ tumors,along with multimodal diagnostic methods for detecting *** for tumor therapy,cutting-edge drug delivery methods that can cross biological barriers and the pinpoint targeting of tumor lesions for precise medical intervention are *** the domain of therapeutic diagnostics,we elucidate the theoretical underpinnings and structural paradigms that underlie a spectrum of advanced diagnostic and therapeutic ***,we present a compendium of publications delineating the clinical applications of each nano-based theragnostic integration ***,this comprehensive review discusses the safety concerns pertaining to the clinical application of nanoparticles and proposes some strategic recommendations to enhance the precision and safety of theragnostic-guided,nanotechnology-based clinical practices.A deeper understanding of nanomaterials,together with intimate interdisciplinary collaborations,nano-wave will most probably guide human beings to win the battle against cancers.

关键词： nanoparticles drug delivery gastric cancer glioma glioblastoma

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黄山市民宿空间集聚特征及影响因素研究

资源开发与市场 2021年第8期37卷 914-920页

作者：吴欢欢李天宇符琳蓉陆林安徽师范大学地理与旅游学院安徽芜湖241002

运用POI数据抓取技术,以ArcGIS10.2为操作平台,采用最邻近分析、不平衡指数、核密度分析、缓冲区分析和地理探测器等方法综合研究了黄山市民宿空间集聚特征及其影响因素。结果表明:①黄山市民宿呈显著集聚状态,空间分布不均衡。②民宿... 详细信息

运用POI数据抓取技术,以ArcGIS10.2为操作平台,采用最邻近分析、不平衡指数、核密度分析、缓冲区分析和地理探测器等方法综合研究了黄山市民宿空间集聚特征及其影响因素。结果表明:①黄山市民宿呈显著集聚状态,空间分布不均衡。②民宿整体呈现“一主三次多中心”的集聚态势。③基于对自然环境、社会经济、区位交通、旅游影响4大维度共10个影响因素的进一步分析可知,旅游影响维度影响力最大,社会经济维度影响力最小;民宿分布具有高等级景区依赖性、交通干线依托性、盆地与谷地趋向性、人口趋向性。

关键词：民宿空间集聚影响因素黄山市

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长三角地区高质量发展评价

资源开发与市场 2022年第8期38卷 955-963页

作者：毕珊珊李冬花符琳蓉蔡小倩陆林安徽师范大学地理与旅游学院安徽芜湖241000

高质量发展作为新发展阶段重点贯彻落实的发展主题,对我国经济社会发展具有重要意义。基于新发展理念,采用熵值法和障碍度模型对长三角地区2009年、2014年和2019年的高质量发展状况及主要障碍因子进行测度与识别。结果表明:①长三角地... 详细信息

高质量发展作为新发展阶段重点贯彻落实的发展主题,对我国经济社会发展具有重要意义。基于新发展理念,采用熵值法和障碍度模型对长三角地区2009年、2014年和2019年的高质量发展状况及主要障碍因子进行测度与识别。结果表明:①长三角地区高质量发展综合指数持续增长,不同等级的城市渐趋向高值区城市转变,总体呈“东南高、西北低”的发展格局。②创新、协调、开放和共享发展水平与城市综合发展水平关联性较强,绿色发展水平的结果与此相异。③五大子系统障碍度排序为:创新发展>开放发展>共享发展>协调发展>绿色发展。④未来的发展应尊重区域差异,缩小区域差距,加强人才和科技的培育及跨区域流通,建设服务型政府,以促进长三角一体化高质量发展。

关键词：高质量发展新发展理念一体化发展长三角地区

Pancreatic stent improves the success rate of needle-knife papillotomy in patients with difficult biliary cannulation

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World Journal of Gastroenterology 2025年第1期31卷 58-67页

作者： Mu-Hsien Lee Cheng-Hui lin Chi-Huan Wu Yung-Kuan Tsou Kai-Feng Sung Sheng-fu Wang Nai-Jen Liu Department of Gastroenterology and Hepatology Chang Gung Memorial Hospital and Chang Gung University College of MedicineTaoyuan 33305Taiwan School of Medicine Chang Gung UniversityTaoyuan 33305Taiwan

BACKGROUND Needle-knife precut papillotomy(NKP)is typically performed ***,it remains unclear whether pancreatic stent(PS)placement can improve the outcomes of *** To explore whether PS placement improves the success rate of NKP in patients with difficult biliary *** This single-center retrospective study included 190 patients who underwent NKP between January 2017 and December 2021 after failed conventional biliary *** cases with incidental pancreatic duct cannulation during conventional biliary cannulation,the decision for pre-NKP PS placement was made at the endoscopist's *** primary outcome was the difference in the NKP success rate between patients with and without PS placement;the secondary outcome was the adverse event *** Among the 190 participants,82 received pre-NKP PS(PS-NKP group)whereas 108 did not[freehand or freehand NKP(FH-NKP)group].Post-NKP selective biliary cannulation was successful in 167(87.9%)patients,and the PS-NKP had a significantly higher success rate than the FH-NKP group(93.9%vs 83.3%,P=0.027).The overall adverse event rates were 7.3%and 11.1%in the PS-NKP and FH-NKP groups,respectively(P=0.493).A periampullary diverticulum(PAD)and significant intraoperative bleeding during NKP were independently associated with NKP failure;however,a pre-NKP PS was the only predictor of NKP *** the 44 participants with PADs,the PS-NKP group had a non-significantly higher NKP success rate than the FH-NKP group(87.5%and 65%,respectively;P=0.076).CONCLUSION PS significantly improved the success rate of NKP in patients with difficult biliary cannulation.

关键词： Difficult biliary cannulation Endoscopic retrograde cholangiopancreatography Needle-knife papillotomy Pancreatic stent Selective biliary cannulation