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Promoting role of an endophyte on the growth and contents of kinsenosides and flavonoids of Anoectochilus formosanus Hayata,a rare and threatened medicinal Orchidaceae plant

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2013年第9期14卷 785-792页

作者： fu-sheng ZHANG Ya-li lv Yue ZHAO Shun-xing GUO Institute of Medicinal Plant Development Chinese Academy of Medical Sciences & Peking Union Medical College Modern Research Center for Traditional Chinese Medicine Shanxi University Department of Pharmaceutical Affairs Beijing Chao-Yang Hospital School of Traditional Chinese Material Medica Shenyang Pharmaceutical University

Anoectochilus formosanus,commonly known as "Jewel Orchid",is a Chinese folk medicine used to treat hypertension,diabetes,and heart *** existence of *** is currently threatened by habitat loss,human and animal consumption,*** highly potent medicinal activity of *** is due to its secondary metabolites,especially kinsenosides and *** orchid also has a unique mycorrhizal *** adult orchids rely on endophytes for mineral nutrition and have complex interactions with them,which are related to plant growth,yield and changes in secondary *** study investigated the promoting role of F-23 fungus (genus Mycena) on the biomass and contents of kinsenosides and flavonoids of *** in pot *** following were observed after 10 weeks of symbiotic cultivation:increased shoot height,shoot dry weight,and leaf numbers by 16.6%,31.3%,and 22.5%,respectively;increased contents of kinsenosides,isorhamnetin-3-O-β-D-rutinoside,and isorhamnetin-3-O-β-D-glucopyranoside by 85.5%,226.1%,and 196.0%,respectively;some hyphae in epidermal cells dyed red and/or reddish brown by safranine;and,significantly reduced number of starch grains in cortical ***,F-23 fungus significantly improved the kinsenoside and flavonoid contents of *** findings supported the reports that endophytes can alter the production of secondary metabolites in their plant hosts,although further physiological,genetic and ecological analyses are warranted.

关键词： Anoectochilus formosanus Endophyte Secondary metabolite Kinsenoside Flavonoid

Fabrication and properties of lightweight zirconia with fine closed porosity

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Journal of Iron and Steel Research International 2024年第6期31卷 1449-1458页

作者： Yi-bo Zhang Hua-zhi Gu lv-ping fu Ao Huang Mei-je Zhang The State Key Laboratory of Refractories and Metallurgy Wuhan University of Science and TechnologyWuhan 430081HubeiChina

Lightweight refractory materials with thermal insulation properties and erosion resistance are advantageous for hightemperature *** zirconia refractories were prepared using starch as a pore-forming agent,basic magnesium carbonate as a stabilizer,and nano-zirconia as an *** effects of the nano-zirconia content on the pore and thermal insulation properties of the lightweight zirconia refractories were investigated based on the porosity,phase composition,microstructure,and thermal ***-zirconia was shown to have a high surface energy,and its addition effectively increased the driving force for sintering,reduced the sintering temperature,and promoted the sintering reaction,thereby reducing the apparent porosity and improving the density of the prepared *** to the superplasticity of nano-zirconia,the surface stress caused plastic deformation between particles,which increased the migration rate of grain boundaries and trapped more gas inside the material before it diffused to the surface,thereby enhancing the closed porosity of the *** presence of closed pores could extend the thermal conduction path,decrease the conduction rate,and hinder the conduction effect to effectively reduce the thermal conductivity of the *** a nano-zirconia content of 0.75 wt.%,the prepared lightweight zirconia had the highest closed porosity and the lowest thermal *** apparent porosity,closed porosity,and total porosity of the material were 2.8%,7.0%,and 9.8%,respectively,and the thermal conductivity at 800℃was 1.37 W m^(-1)k^(-1).

关键词： Sintering Nano-zirconia Closed pore:Thermal conductivity Refractory material

Mechanical properties and energy absorption of extruded Mg–2.0Zn–0.3Zr alloy with Y addition

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Rare Metals 2015年第5期34卷 314-323页

作者： Bin-Jiang lv Jian Peng Yi Peng Ai-Tao Tang fu-Sheng Pan College of Materials Science and Engineering Chongqing University Chongqing Advanced Materials Research Center Chongqing Academy of Science and Technology

The effects of the rare earth element Y addition on mechanical properties and energy absorption of a low Zn content Mg-Zn-Zr system alloy and the deformation temperature of optimized alloy were investigated by room tensile test, optical microscopy （OM）, X-ray diffraction （XRD）, scanning electron microscopy （SEM）, and transmission electron microscope （TEM）. The results show that, after homogenization at 420℃ for 12 h for the as-cast alloys, MgZn phase forms, which decreases the strength of Mg-2.0Zn-0.3Zr alloy with Y content of 0.9 wt%. The tensile strength and elongation of the alloy with a Y addition of 5.8 wt% reach the max value （281 ±2） MPa and （30.1 ± 0.7） %, respectively; the strength and elongation of Mg-2.0Zn-0.3Zr-0.9Y alloy at the optimized extrusion temperature of 330 ℃ reach （321 ± 1） MPa and （21.9 ± 0.7） %, respectively. The energy absorption increases with the increase of Y content, the max value reached 0.79 MJ·m^-3 with Y content of 5.8 wt%, and the energy absorption of Mg-2.0Zn-0.3Zr-0.9Y alloy at the optimized extrusion temperature of 330 ℃ reaches 0.75 MJ·m^-3.

关键词： Yttrium Microstructure Mechanical properties Energy absorption

Rapamycin reverses ferroptosis by increasing autophagy in MPTP/MPP+-induced models of Parkinson's disease

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Neural Regeneration Research 2023年第11期18卷 2514-2519页

作者： Tongyu Liu Peihan Wang Huan Yin Xiangfei Wang jing lv Jiang Yuan jing Zhu Yunfu Wang Department of Neurology Affiliated Taihe HospitalHubei University of MedicineShiyanHubei ProvinceChina Institute of Neuroscience Hubei University of MedicineShiyanHubei ProvinceChina Wudang Mountain Hospital Area of Taihe Hospital Affiliated Hospital of Hubei University of MedicineShiyanHubei ProvinceChina

Parkinson’s disease is a neurodegenerative disorder,and fe rroptosis plays a significant role in the pathological mechanism underlying Parkinson’s ***,an autophagy inducer,has been shown to have neuroprotective effects in Parkinson’s ***,the link between rapamycin and ferroptosis in Parkinson’s disease is not entirely *** this study,rapamycin was administe red to a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson’s disease mouse model and a 1-methyl-4-phenylpyridinium-induced Parkinson’s disease PC12 cell *** results showed that rapamycin improved the behavioral symptoms of Parkinson’s disease model mice,reduced the loss of dopamine neurons in the substantia nigra pars compacta,and reduced the expression of ferroptosis-related indicators(glutathione peroxidase 4,recombinant solute carrier family 7,member 11,glutathione,malondialdehyde,and reactive oxygen species).In the Parkinson’s disease cell model,rapamycin improved cell viability and reduced ferro *** neuroprotective effect of rapamycin was attenuated by a ferroptosis inducer(methyl(1S,3R)-2-(2-chloroacetyl)-1-(4-methoxycarbonylphenyl)-1,3,4,9-tetrahyyridoindole-3-carboxylate)and an autophagy inhibitor(3-methyladenine).Inhibiting ferro ptosis by activating autophagy may be an important mechanism by which rapamycin exerts its neuroprotective *** re,the regulation of ferroptosis and autophagy may provide a therapeutic target for drug treatments in Parkinson’s disease.

关键词： autophagy behavior ferroptosis MPTP Parkinson’s disease PC12 cell rapamycin tyrosine hydroxylase

Paleoenvironment controls on organic matter accumulation in transitional shales from the eastern Ordos Basin,China

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Frontiers of Earth Science 2021年第4期15卷 737-753页

作者： Jianwei lv Songhang ZHANG Ning YANG Chunbo fu Xinlu YAN Yang LI School of Energy Resources China University of GeosciencesBeijing 100083China Chinese Academy of Natural Resources Economics Beijing 101149China Huadian Coal Industry Group Co. Ltd.Beijing 100035China Second Oil Production Plant PetroChina Changqing Oilfield CompanyQingyang 745100China

To investigate the paleoenvironmental controls on organic matter accumulation of Upper Paleozoic shales in the eastern Ordos Basin,China,26 shale samples were collected from two wells drilled into the Shanxi and Taiyuan *** total organic carbon(TOC)content,mineral compositions and elemental geochemistry of the samples were ***(35.42%)and clay minerals(48.34%)are the dominant minerals and trace elements(Li,Cs,Cu,V,Co,and Cr)are commonly enriched in the shale samples compared to the Upper Continental Crust.C-values(ranging from 0.2 to 4.5),chemical indices of weathering(CIW)values(48.82 to 99.11),and Sr/Cu ratios(1.00 to 11.05)suggest that the paleoclimate was humid in the study area during the Late *** redox indices(e.g.,Al_(2)O_(3)/(Al_(2)O_(3)+Fe_(2)O_(3)),V/Cr,Ni/Co,V/(V+Ni)and U/Th)indicate a dysoxic to oxic paleoenvironment characterized by transi-tional sedimentary deposits in a continental margin *** addition,chemical index of alteration(CIA,ranging from 77.92%to 98.36%)and CIW(89.19%to 99.11%)values suggest that there was intense chemical weathering in the study area,while the Al_(2)O_(3)-CaO^(*)+Na_(2)O-K_(2)O(A-CN-K)ternary diagram demonstrates that the shales were not subjected to potassium metasomatism during ***_(2)O_(3)/TiO_(2)and TiO_(2)/Zr ratios,as well as REE characteristics suggest a felsic source rocks and discount seawater as an REE *** anomalies indicate an oxic environment with terrigenous input during black shale deposition,and LREE enrichment with negative Eu anomalies suggests that both shale formations were affected by detrital input rather than hydrothermal *** correlation of TOC(ranging from 1.10%to 6.39%,with an average of 2.77%)with trace elemental redox indices(Sr/Cu,Sr/Ba,V/Cr,and U/Th)indicates that a warm-humid,dysoxic to oxic environment preserved much of the organic matter.

关键词： Late Paleozoic shale geochemistry paleoenvironment eastern Ordos Basin

Probiotic cocktails accelerate baicalin metabolism in the ileum to modulate intestinal health in broiler chickens

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Journal of Animal Science and Biotechnology 2024年第2期15卷 779-794页

作者： Mingkun Gao Chaoyong Liao Jianyang fu Zhonghua Ning Zengpeng lv Yuming Guo State Key Laboratory of Animal Nutrition and Feeding College of Animal Science and TechnologyChina Agricultural UniversityBeijing 100193China National Engineering Laboratory for Animal Breeding College of Animal Science and TechnologyChina Agricultural UniversityBeijing 100193China

Background Baicalin and probiotic cocktails are promising feed additives with broad application *** probiotic cocktails are known to enhance intestinal health,the potential synergistic impact of combining baicalin with probiotic cocktails on the gut health of broiler chickens remains largely ***,this study aims to investigate the influence of the combined administration of baicalin and probiotic cocktails on the composition of ileal and cecal microbiota in broiler chickens to elucidate the underlying mechanisms responsible for the healthpromoting *** A total of 3201-day-old male Arbor Acres broilers were divided into 4 groups,each with 8 replicates of 10 chicks per *** a period of 42 d,the birds were fed a basal diet or the same diet supplemented with 37.5 g/t baicalin(BC),1,000 g/t probiotic cocktails(PC),or a combination of both BC(37.5 g/t)and PC(1,000 g/t).The results demonstrated that BC+PC exhibited positive synergistic effects,enhancing intestinal morphology,immune function,and barrier *** was evidenced by increased VH/CD ratio,sIgA levels,and upregulated expression of occludin and claudin-1(P<0.05).16S rRNA analysis indicated that PC potentiated the effects of BC,particularly in the ileum,where BC+PC significantly increased theα-diversity of the ileal microbiota,altered itsβ-diversity,and increased the relative abundance of Flavonifractor(P<0.05),a flavonoid-metabolizing ***,Flavonifractor positively correlated with chicken ileum crypt depth(P<0.05).While BC+PC had a limited effect on cecal microbiota structure,the PC group had a very similar microbial composition to BC+PC,suggesting that the effect of PC at the distal end of the gut overshadowed those of *** We demonstrated the synergistic enhancement of gut health regulation in broiler chickens by combining baicalin and probiotic *** cocktails enhanced the effects of baicalin and accelerated its metab

关键词： Baicalin Gut health Ileal microbiota Probiotic cocktails Synergistic effects

Preparation and characterization of Cu2ZnSn(S,Se)4 film by drop-coating of Cu2ZnSnS4 nanoink

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Rare Metals 2016年第9期35卷 718-722页

作者： Xiao-Gong lv jing-Yu Wang Cheng-Jun Zhu Zhi-Ping Wang Key Laboratory of Semiconductor Photovoltaic Technology of Inner Mongolia Autonomous Region School of Physical Science and TechnologyInner Mongolia UniversityHohhot 010021China Ordos Institute of Technology Ordos 017000China

In this work,a simple and facile one-pot oleylamine solvothermal synthetic method was developed to synthesize Cu2ZnSnS4（CZTS） *** the Cu2ZnSn（S,Se）4（CZTSSe） thin films were prepared by selenizing CZTS *** obtained CZTS nanocrystals and CZTSSe films were studied using X-ray diffraction（XRD）,transmission electron microscopy（TEM）,scanning electron microscopy（SEM）,energy-dispersive X-ray spectroscopy（EDX）,and ultraviolet–visible spectrophotometer（UV–Vis）.TEM results show that the sphere–like CZTS nanoparticles with diameter between 12 and 35 nm are *** studies indicate that the prepared CZTS nanocrystals form kesterite crystal structure,and the CZTSSe films with kesterite crystal structure are also obtained at the annealing temperatures of 500 and550 °*** particular after annealing at 500 °C for 20 min,the CZTSSe film exhibits a smooth,uniform,crack-free,and large-grained topography and possesses Cu-poor and Sn-rich ***,it shows strong optical absorption from visible to near-infrared（IR） region,and its optical band gap（Eg） is found to be about 1.44 e V.

关键词： Thin films Oleylamine solvothermal Crystal structure CZTS nanocrystals

Investigation of relationships among gastroesophageal reflux disease subtypes using narrow band imaging magnifying endoscopy

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World Journal of Gastroenterology 2013年第45期19卷 8391-8397页

作者： jing lv Dong Liu Shi-Yang Ma Jun Zhang Department of Gastroenterology the Second Affiliated Hospital of Xi’an Jiaotong University School of Medicine

AIM:To investigate the relationships among subtypes of gastroesophageal reflux disease(GERD)using narrow band imaging(NBI)magnifying ***:A reflux disease questionnaire was used to screen 120 patients representing the three subtypes of GERD(n=40 for each subtypes):nonerosive reflux disease(NERD),reflux esophagitis(RE)and Barrett’s esophagus(BE).NBI magnifying endoscopic procedure was performed on the patients as well as on 40 healthy *** demographic and clinical characteristics,and NBI magnifying endoscopic features,were recorded and compared among the *** biopsy and histopathological examination were conducted if there were any *** 18.0 software was used for all statistical ***:Compared with healthy controls,a significantly higher proportion of GERD patients had increased number of intrapapillary capillary loops(IPCLs)(78.3%vs 20%,P<0.05),presence of microerosions(41.7%vs 0%,P<0.05),and a non-round pit pattern below the squamocolumnar junction(88.3%vs 30%,P<0.05).The maximum(228±4.8 vs 144±4.7,P<0.05),minimum(171±3.8 vs 103±4.4,P<0.05),and average(199±3.9 vs 119±3.9,P<0.05)numbers of IPCLs/field were also significantly greater in GERD ***,comparison among groups of the three subtypes showed no significant differences or any linear trend,except that microerosions were present in 60%of the RE patients,but in only 35%and 30%of the NERD and BE patients,respectively(P<0.05).CONCLUSION:Patients with GERD,irrespective of subtype,have similar micro changes in the distal *** three forms of the disease are probably independent of each other.

关键词： Gastroesophageal reflux Gastroesophageal reflux disease Intrapapillary capillary loops Magnifying endoscopy Narrow band imaging

Group 3 innate lymphoid cells: intestinal patrolling guardians bullied by T cells

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Cellular & Molecular Immunology 2023年第2期20卷 115-116页

作者： Xinping lv Shan Zhu jing Wu jingtao Chen Cancer Center First Hospital of Jilin UniversityChangchun130021JilinChina Laboratory for Tumor Immunology First Hospital of Jilin UniversityChangchun130061JilinChina

Since the discovery of group 3 innate lymphoid cells(ILC3s),many studies have reported that,in addition to T cells,ILC3s also play an indispensable role in intestinal immune surveillance,host defense,and homeostasis[1].Although both ILC3s and T cells regulate intestinal inflammation through the secretion of interleukin(IL)-22,differences in the behaviors of these two cell types,especially the dynamic shift and mechanism of ILC3 regulation between normal and inflammatory states,remain unclear.A recent paper by Jarade et al.[2]published in Nature Immunology reported that intestinal ILC3s under basal conditions are immotile and arrested in the presence of T ***,the environmental T cells,the microbiota,and the chemokine CCL25 jointly shape ILC3 patrolling behavior and their effector function of maintaining intestinal barrier integrity via *** findings facilitate the study of ILC biodynamics and ILC immune regulation and the search for therapeutic strategies for gastrointestinal diseases.

关键词： lymphoid jointly guard