检索结果-南通市图书馆

The effects of a 20-week exercise program on blood-circulating biomarkers related to brain health in overweight or obese children:The Activebrains project

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Sport and Health Science 2023年第2期12卷 175-185页

作者： María Rodriguez-Ayllon Abel Plaza-Florido Andrea Mendez-Gutierrez Signe Altmäe Patricio Solis-Urra Concepción M.Aguilera Andrés Catena francisco b.ortega Irene Esteban-Cornejo PROFITH“PROmoting FITness and Health through physical activity”research group Sport and Health University Research Institute(iMUDS)Department of Physical and Sports EducationFaculty of Sport SciencesUniversity of GranadaGranada 18071Spain Department of Epidemiology Erasmus University Medical CenterRotterdam 3015 GDthe Netherlands Department of biochemistry and Molecular biology Ⅱ School of PharmacyUniversity of GranadaGranada 18071Spain Department of biochemistry and Molecular biology Faculty of SciencesUniversity of GranadaGranada 18071Spain Nuclear Medicine Services Virgen de Las Nieves University HospitalGranada 18014Spain Faculty of Education and Social Sciences Universidad Andres BelloViña del Mar 2531015Chile Department of Experimental Psychology School of PsychologyUniversity of GranadaGranada 18011Spain Faculty of Sport and Health Sciences University of JyväskyläJyväskylä40014Finland Department of bioscience and Nutrition Karolinska InstitutetHuddingeSE 14157Sweden

background:Emerging research supports the idea that exercise positively affects ***,the mechanisms linking exercise with brain health are largely *** aimed to investigate the effect of exercise on(a)blood biomarkers selected based on previous evidence(brainderived neurotrophic factor,β-hydroxybutyrate(bHb),cathepsin b(CTSb),kynurenine,fibroblast growth factor 21(FGF21),soluble vascular cell adhesion molecule-1(sVCAM-1));and(b)a panel of 92 neurology-related proteins(discovery analysis).We also investigated whether changes in these biomarkers mediate the effects of exercise on brain health(hippocampal structure and function,cognitive performance,and mental health).Methods:We randomized 81 overweight/obese children(10.1±1.1 years,41%girls)into 2 groups:either 20 weeks of aerobic plus resistance exercise or *** biomarkers were assessed using enzyme-linked immunosorbent assay(ELISA)for kynurenine,FGF21,and CTSb;colorimetry forβ-hydroxybutyrate;and XMap for brain-derived neurotrophic factor and soluble vascular cell adhesion ***92 neurology-related proteins were analyzed by an antibody-based proteomic ***:Our intervention had no significant effect on candidate biomarkers(all p>0.05).In the discovery analysis,a reduction in circulating macrophage scavenger receptor type-I was observed(standardized differences between groups=-0.3,p=0.001).This effect was validated using ELISA methods(standardized difference=-0.3,p=0.01).None of the biomarkers mediated the effects of exercise on brain ***:Our study does not support a chronic effect of exercise on candidate *** observed that while chronic exercise reduced the levels of macrophage scavenger receptor type-Ⅰ,it did not mediate the effects of exercise on brain *** studies should explore the implications of this novel biomarker for overall health.

关键词： brain development Childhood MRI Physical activity Proteomic

Mediation role of cardiorespiratory fitness on the association between fatness and cardiometabolic risk in European adolescents: The HELENA study

在线全文

学校读者我要写书评

暂无评论

Journal of Sport and Health Science 2021年第3期10卷 360-367页

作者： Carlos Cristi-Montero Javier Courel-Ibanez francisco b.ortega Jose Castro-Pinero Alba Santaliestra-Pasias Angela Polito Jeremy Vanhelst Ascension Marcos Luis M.Moreno Jonatan R.Ruiz IRyS Group Physical Education SchoolPontificia Universidad Catolicade ValparaisoValparaisso 2530388Chile Department of Physical Activity and Sport Faculty of Sport SciencesUniversity of MurciaMurcia 30071Spain PROmoting FITness and Health through Physical Activity Research Group(PROFITH) Department of Physical Education and SportsFaculty of Sport SciencesUniversity of GranadaGranada 18001Spain Department of Physical Education Faculty of Education SciencesUniversity of CadizPuerto Real 11003Spain Department of Health and Human Performance School of Health SciencesUniversity of ZaragozaZaragoza 50001Spain Growth ExerciseNutrition and Development(GENUD)Research GroupZaragoza 50001Spain National Institute for Food and Nutrition Research Rome 80070Italy Lille Inflammation Research International Center University of LilleLille 59000France Immunonutrition Research Group Department Metabolism and NutritionInstitute of Food Science and Technology and Nutrition(ICTAN)Spanish National Research Council(CSIC)Madrid E-28040 Spain

Purpose:This study was aimed to analyze the mediation role of cardiorespiratory fitness(CRF)on the association between fatness and cardiometabolic risk scores(CMRs)in European ***:A cross-sectional study was conducted in adolescents(n=525;46%boys;14.1±1.1 years old,mean ±SD)from 10 European cities involved in the Healthy Lifestyle in Europe by Nutrition in Adolescence *** was measured by means of the shuttle run test,while fatness measures included body mass index(bMI),waist to height ratio,and fat mass index estimated from skinfold thicknesses.A clustered CMRs was computed by summing the standardized values of homeostasis model assessment,systolic blood pressure,triglycerides,total cholesterol/highdensity lipoprotein cholesterol ratio,and ***:Linear regression models indicated that CRF acted as an important and partial mediator in the association between fatness and CMRs in 1217-year-old adolescents(for bMI:coefficients of the indirect role b=0.058(95%confidence interval(95%CI):0.023-0.101),Sobel test z=3.11(10.0%mediation);for waist to height ratio:b=4.279(95%CI:2.242-7.059),z=3.86(11.5%mediation);and for fat mass index:b=0.060(95%CI:0.020-0.106),z=2.85(9.4%mediation);all pbetween fatness and CMRs could be partially decreased with improvements to fitness levels;therefore,CRF contribution both in the clinical field and public health could be important to consider and promote in adolescents independently of their fatness levels.

关键词： Cardiovascular disease Children Fat mass Fitness Health Physical activity

Cardiometabolic risk through an integrative classification combining physical activity and sedentary behavior in European adolescents:HELENA study

在线全文

学校读者我要写书评

暂无评论

Journal of Sport and Health Science 2019年第1期8卷 55-62页

作者： Carlos Cristi-Montero Palma Chillón Idoia Labayen José A.Casajus Marcela Gonzalez-Gross Jérémy Vanhelst Yannis Manios Luis A.Moreno francisco b.ortega Jonatan R.Ruiz IRyS Group Physical Education School Pontificia Universidad Cato?lica de Valparai?o PROmoting FITness and Health through physical activity research group (PROFITH) Department of Physical Education and SportsFaculty of Sport Sciences University of Granada Department of Nutrition and Food Science University of the Basque Country Department of Health and Human Performance School of Health Sciences University of Zaragoza ImFine Research Group Facultad de Ciencias de la Actividad Física y del Deporte-INEF Universidad Politcnica de Madrid Lille Inflammation Research International Center University of Lille Department of Nutrition and Dietetics Harokopio University

Purpose: This study aims to compare adolescents' cardiometabolic risk score through an integrative classification of physical activity(PA),which involves the combination of moderate-to-vigorous physical activity(MVPA) and sedentary behavior(Sb).Methods: A cross-sectional study derived from the Healthy Lifestyle in Europe by Nutrition in Adolescence Cross-Sectional Study database(2006-2008) was conducted in adolescents(n = 548; boys, 47.3%; 14.7 ± 1.2 years) from 10 European cities. MVPA and Sb were objectively measured using accelerometry. Adolescents were divided into 4 categories according to MVPA(meeting or not meeting the international recommendations) and the median of Sb time(above or below sex-and age-specific median) as follows: High-Sb & Inactive, Low-Sb & Inactive,High-Sb & Active, and Low-Sb & Active. A clustered cardiometabolic risk score was computed using the homeostatic model assessment, systolic blood pressure, triglycerides, total cholesterol/high-density lipoprotein cholesterol, sum 4 skinfolds, and cardiorespiratory fitness(CRF).Analyses of covariance were performed to discern differences on cardiometabolic risk scores among PA categories and each health ***: The cardiometabolic risk score was lower in adolescents meeting the MVPA recommendation and with less time spent in Sb in comparison to the high-Sb & Inactive group(p bolic risk score was established between High-Sb or Low-Sb groups in inactive adolescents. It is important to note that CRF was the only variable that showed a significant modification(higher)when children were compared from the category of physically inactive with "active" but not from high-to ***: being physically active is the most significant and protective outcome in adolescents to reduce cardiometabolic risk. Lower Sb does not exhibit a significant and extra beneficial difference.

关键词： Accelerometry Cardiovascular disease Exercise Metabolic disease Sedentary lifestyles

blood Flow-Restricted Training in Older Adults:A Narrative Review

在线全文

学校读者我要写书评

暂无评论

Journal of Science in Sport and Exercise 2020年第1期2卷 25-37页

作者： Abel Plaza-Florido Jairo H.Migueles Antonio Piepoli Pablo Molina-Garcia Maria Rodriguez-Ayllon Cristina Cadenas-Sanchez Jose Mora-Gonzalez Irene Esteban-Cornejo francisco b.ortega PROFITH"PROmoting FITness and Health Through Physical Activity"Research Group Sport and Health University Research Institute(iMUDS)Department of Physical and Sports EducationFaculty of Sport SciencesUniversity of GranadaCarretera de Alfacars/nCP 18071 GranadaSpain Department of Health Sciences Faculty of Health SciencesUniversity of JaénResearch Group CTS-026:Study Group on Physical ActivityPhysiotherapy and HealthJaénSpain Department of Rehabilitation Sciences KU Leuven-University of LeuvenLeuvenBelgium Department of Psychology Center for Cognitive and Brain HealthNortheastern UniversityBostonMAUSA

background Low-intensity resistance training(LI-RT)combined with blood flow restriction(bFR)is an alternative to traditional moderate-high-intensity resistance training to increase strength and muscle ***,the evidence about the efficacy of this novel training method to increase strength and muscle mass in healthy and older adults with patholo-gies is ***,the possible risk and adverse effects with bFR training methodology in older adults should be ***(1)To summarize the current evidence on training with bFR strategies in older adults aiming to improve strength and to increase muscle mass;and(2)to provide recommendations for resistance and aerobic training with bFR in older adults based on the studies *** Studies that investigated the chronic responses to resistance training or aerobic training with bFR related to strength and muscle mass changes in older adults were *** independent researchers conducted the search in PubMed,Web of Science,and Google Scholar databases from their inception up to November 1,*** Seventeen out of 35 studies,which performed resistance or aerobic training with bFR in older adults focused on strength and muscle mass outcomes,were included in this *** performing resistance and aerobic train-ing with bFR found better improvements in strength and higher increase in muscle mass compared to non-bFR groups that performed the same training ***-intensity resistance training(HI-RT)without bFR provided greater improvements in strength and a similar increase in muscle mass compared to light-intensity resistance training(LI-RT)with *** Current evidence suggests that LI-RT and/or aerobic training with bFR improves strength and increases muscle mass in older ***-intensity training without bFR would normally not obtain such ***,LI-RT and aerobic training with bFR is an alternative to traditional methods to improve strength an

关键词： Hyertroply Strength Vascular oclusion Reistance raining Elderly aduts

Protein glycation:a wolf in sweet sheep’s clothing behind neurodegeneration

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第5期19卷 975-976页

作者： Ana b.Uceda francisco Leal-Pérez Miquel Adrover Institut Universitari d’Investigacióen Ciències de la Salut(IUNICS) Institut d’InvestigacióSanitària Illes balears(IdISba) Departament de Química Universitat de les Illes BalearsCtraPalma de MallorcaSpain

At the beginning of the 16th century,Paracelsus coined the maxim:“the dose makes the poison”.This principle can be applied to all living organisms,including organs and *** brain and its glial and neuronal cells are ... 详细信息

关键词： organs sheep sweet

Social networks of reintroduced Przewalski's horses in the Great Gobi b Strictly Protected Area (Mongolia)

在线全文

学校读者我要写书评

暂无评论

Current Zoology 2024年第2期70卷 182-194页

作者： Anna bernatkova Ganbaatar Oyunsaikhan Jaroslav Simek Martina Komarkova francisco Ceacero Faculty of Tropical AgriSciences Czech University of Life Sciences PragueCzech Republic Great Gobi b Strictly Protected Area Takhin TalMongolia Zoo Praha U Trojského zamku 120/3PragueCzech Republic

Analyzing social networks is a powerful tool for understanding the ecology of social *** most studies focus on the role of each group member,few compare groups with different *** current population of Przewalski's horses Equus ferus przewalskii at the Great Gobi b Strictly Protected Area(Mongolia)includes groups of wild-born and captive-bred individuals with different experiences with the area(acclimatizing,long-term reintroduced,and wild-born),therefore serving as an ideal natural behavioral *** filmed 11 groups for 141.5 hours in summer 2018(July),late spring 2019(May,June),and autumn 2019(September,October).Affiliative and agonistic interactions were recorded,and social networks were *** tested the influence of origin,experience,season,sex,age,relative time belonging to the group,relat-edness,and dominance rank on different network indices at the individual and group *** found that groups with greater experience in the area are generally better connected than members of the newly formed ***,these strong networks were created by wild-born individuals with very low interaction *** the contrary,inexperienced groups composed of captive-bred individuals displayed many inter actions but created weak social *** results show a trend of behavioral transition from acclimatizing through long-term reintroduced to wild-born groups,supporting that the newly formed groups of released Przewalski's horses need time to display the typical social behavior patterns of wild-born ***-term monitoring of released Przewalski's horses is recommended to promote the success of this reintroduction program.

关键词： Przewalski's horses reintroduction social behavior soft-release.

Fully integrated and broadband Si-rich silicon nitride wavelength converter based on bragg scattering intermodal four-wave mixing

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Photonics Research 2024年第3期12卷 I0001-I0010页

作者： VALERIO VITALI THALÍA DOMÍNGUEZ bUCIO HAO LIU JOSÉMANUEL LUQUE GONZÁLEZ francisco JURADO-ROMERO ALEJANDRO ortega-MOÑUX GLENN CHURCHILL JAMES C.GATES JAMES HILLIER NIKOLAOS KALFAGIANNIS DANIELE MELATI JENS H.SCHMID ILARIA CRISTIANI PAVEL CHEbEN J.GONZALO WANGÜEMERT-PÉREZ ÑIGO MOLINA-FERNÁNDEZ FREDERIC GARDES COSIMO LACAVA PERIKLIS PETROPOULOS Optoelectronics Research Centre University of SouthamptonSouthampton SO171BJUK Electrical Computer and Biomedical Engineering DepartmentUniversity of PaviaPavia 27100Italy Telecommunication Research Institute(TELMA) Universidad de MálagaCEI Andalucı´a TECHE.T.S.I.Telecomunicación29010 MálagaSpain School of Science and Technology Nottingham Trent UniversityNottingham NG118NSUK Department of Electrical Engineering Eindhoven University of TechnologyEindhoven 5600 MBThe Netherlands Department of Materials Science and Engineering University of IoanninaIoannina 45110Greece Centre de Nanosciences et de Nanotechnologies UniversitéParis-SaclayCNRS91120 PalaiseauFrance Advanced Electronics and Photonics Research Center National Research Council CanadaOttawaOntario K1A 0R6Canada

Intermodal four-wave mixing(FWM)processes have recently attracted significant interest for all-optical signal processing applications thanks to the possibility to control the propagation properties of waves exciting distinct spatial modes of the same *** allows,in principle,to place signals in different spectral regions and satisfy the phase matching condition over considerably larger bandwidths compared to intramodal ***,the demonstrations reported so far have shown a limited bandwidth and suffered from the lack of on-chip components designed for broadband manipulation of different *** demonstrate here a silicon-rich silicon nitride wavelength converter based on bragg scattering intermodal FWM,which integrates mode conversion,multiplexing and de-multiplexing functionalities *** system enables wavelength conversion between pump waves and a signal located in different telecommunication bands(separated by 60 nm)with a 3 db bandwidth exceeding 70 nm,which represents,to our knowledge,the widest bandwidth ever achieved in an intermodal FWM-based system.

关键词： scattering pump modal

Muscle strength deficits are associated with low bone mineral density in young pediatric cancer survivors:The iboneFIT project

在线全文

学校读者我要写书评

暂无评论

Journal of Sport and Health Science 2024年第3期13卷 419-427页

作者： Andres Marmol-Perez Jose J.Gil-Cosano Esther Ubago-Guisado francisco J.Llorente-Cantarero Juan francisco Pascual-Gázquez Kirsten K.Ness Vicente Martinez-Vizcaino Jonatan R.Ruiz Luis Gracia-Marco Department of Physical Education and Sports Faculty of Sport SciencesSport and Health University Research Institute(iMUDS)University of GranadaGranada 18011Spain Department of Epidemiology and Cancer Control St.Jude Children's Research HospitalMemphisTN 38105USA Department of Communication and Education Loyola University AndalusiaSeville 41704Spain biosanitary Research Institute ibs.GranadaGranada 18012Spain Maimonides biomedical Research Institute of Cordoba(IMIbIC) Cordoba 14004Spain CIbERObN Biomedical Research Networking Center for Physiopathology of Obesity and NutritionCarlos III Health InstituteMadrid 28029Spain Department of Specific Didactics Faculty of EducationUniversity of CordobaCordoba 14071Spain Pediatric and adolescent hematology and oncology service Pediatrics and Pediatric Surgery Clinical Management UnitVirgen de las Nieves University HospitalGranada 18014Spain Health and Social Research Center Universidad de Castilla-La ManchaCuenca 13001Spain

background Pediatric cancer survivors are at increased risk of muscle weakness and low areal bone mineral density(abMD).However,the prevalence of muscle strength deficits is not well documented,and the associations of muscle strength with abMD are unknown in this ***,this study aimed to investigate the prevalence of upper-and lower-body muscle strength deficits and to examine the associations of upper-and lower-body muscle strength with age-,sex,and race-specific abMD Z-scores at the total body,total hip,femoral neck,and lumbar *** This cross-sectional study included 116 pediatric cancer survivors(12.1±3.3 years old,mean±SD;42.2%female).Upper-and lower-body muscle strength were assessed by handgrip and standing long jump test,***‑energy X‑ray absorptiometry was used to measure abMD(g/cm2).Associations between muscle strength and abMD were evaluated in multivariable linear regression *** regression was used to evaluate the contribution of muscle strength(1-decile lower)to the odds of having low abMD(Z-score≤1.0).All analyses were adjusted for time from treatment completion,radiotherapy exposure,and body mass *** More than one-half of survivors were within the 2 lowest deciles for upper-(56.9%)and lower-body muscle strength(60.0%)in comparison to age-and sex-specific reference *** strength deficits were associated with lower abMD Z-scores at all sites(b=0.133–0.258,p=0.001–0.032).Each 1-decile lower in upper-body muscle strength was associated with 30%–95%higher odds of having low abMD Z-scores at all *** 1-decile lower in lower-body muscle strength was associated with 35%–70%higher odds of having low abMD Z-scores at total body,total hip,and femoral *** Muscle strength deficits are prevalent in young pediatric cancer survivors,and such deficits are associated with lower abMD Z-scores at all *** results suggest that interventions designed to improve muscle strength in t

关键词： bone health Childhood cancer DXA Lean mass Resistance training

Plant triterpenoid saponins function as susceptibility factors to promote the pathogenicity of botrytis cinerea

在线全文

学校读者我要写书评

暂无评论

Molecular Plant 2024年第7期17卷 1073-1089页

作者： francisco J.Escaray Amelia Felipo-benavent Cristian J.Antonelli begona balaguer Maria Pilar Lopez-Gresa Pablo Vera Instituto de biologia Molecular y Celular de Plantas Universidad Politecnica de Valencia-C.S.l.CCiudad Politecnica de la InnovacionEdificio 8Eacceso GIngeniero Fausto Elios/n46022ValenciaSpain

The gray mold fungus botrytis cinerea is a necrotrophic pathogen that causes diseases in hundreds of plant species,including high-value *** polyxenous nature and pathogenic success are due to its ability to perceive host signals in its *** this study,we found that laticifer cells of Euphorbia lathyris are a source of susceptibility factors required by *** to cause ***,poor-in-latex(pil)mutants,which lack laticifer cells,show full resistance to this pathogen,whereas lot-of-latex mutants,which produce more laticifer cells,are *** S factors are triterpenoid saponins,which are widely distributed natural products of vast structural *** downregulation of laticifer-specific oxydosqualene cyclase genes,which encode the first committed step enzymes for triterpene and,therefore,saponin biosynthesis,conferred disease resistance to ***,the Medicago truncatula Iha-1 mutant,compromised in triterpenoid saponin biosynthesis,showed enhanced ***,the application of different purified triterpenoid saponins pharmacologically complemented the diseaseresistant phenotype ofpil and hla-1 mutants and enhanced disease susceptibility in different plant *** found that triterpenoid saponins function as plant cues that signal transcriptional reprogramming in ***,leading to a change in its growth habit and infection strategy,culminating in the abundant formation of infection cushions,the multicellular appressoria apparatus dedicated to plant penetration and biomass destruction in *** together,these results provide an explanation for how plant triterpenoid saponins function as disease susceptibility factors to promote *** pathogenicity.

关键词： Euphorbia lathyris laticifer cell latex appressorium infection cushion necrotrophic fungi