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Evolving thoracic surgery: from open surgery to single port thoracoscopic surgery and future robotic

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Chinese Journal of Cancer Research 2013年第1期25卷 4-6页

作者： Diego gonzalez-Rivas Corua University Hospital (CHUAC) and Minimally Invasive Thoracic Surgery Unit (UCTMI) Corua Spain

Thoracic Surgery is a continuous evolving specialty. In the past, thoracic surgeons had to make large incisions in order to operate any pathology inside the chest. This often meant big, painful and ugly scars and long recovery times after surgery. But he history of thoracic surgery changed since the begining of video-assisted thoracoscoDic surgery （VATg3

关键词： from open surgery to single port thoracoscopic surgery and future robotic VATS Evolving thoracic surgery Figure

Intraexaminer repeatability and agreement in stereoacuity measurements made in young adults

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International Journal of Ophthalmology(English edition) 2015年第2期8卷 374-381页

作者： Beatriz Antona Ana Barrio Isabel Sanchez Enrique gonzalez Guadalupe gonzalez Department of Optics II (Optometry and Vision) Faculty of Optics and Optometry Complutense University of Madrid

AIM: To determine the repeatability and agreement of stereoacuity measurements made using some of the most widely used clinical tests: Frisby, TNO, Randot and ***: Stereoacuity was measured in two different sessions separated by a time interval of at least 24 h but no longer than 1wk in 74 subjects of mean age 20.6y using the four methods. The study participants were divided into two groups: subjects with normal binocular vision and subjects with abnormal binocular ***: Best repeatability was shown by the Frisby and Titmus [coefficient of repeatability(COR): ±13 and±12s arc respectively] in the subjects with normal binocular vision though a clear ceiling effect was *** the subjects with abnormal binocular vision, best repeatability was shown by the Frisby(COR: ±69s arc)and Randot(COR: ±72s arc). In both groups, the TNO test showed poorest agreement with the other ***:Therepeatabilityofstereoacuitymeasures was low in subjects with poor binocular vision yet fairly good in subjects with normal binocular vision with the exception of the TNO test. The reduced agreement detected between the tests indicates they cannot be used interchangeably.

关键词： stereoacuity repeatability agreement tereopsis

Modulation of cell physiology under hypoxia in pancreatic cancer

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World Journal of Gastroenterology 2021年第28期27卷 4582-4602页

作者： Matias Estaras Antonio gonzalez Department of Physiology Institute of Molecular Pathology BiomarkersUniversity of ExtremaduraCaceres 10003Spain Department of Physiology Cell Biology and Communication Research GroupUniversity of ExtremaduraCaceres 10003Spain

In solid tumors,the development of vasculature is,to some extent,slower than the proliferation of the different types of cells that form the tissue,both cancer and stroma *** a consequence,the oxygen availability is compromised and the tissue evolves toward a condition of *** presence of hypoxia is variable depending on where the cells are localized,being less extreme at the periphery of the tumor and more severe in areas located deep within the tumor ***,the cells do not *** pathways that are critical for cell fate such as endoplasmic reticulum stress,apoptosis,autophagy,and others are all involved in cellular responses to the low oxygen availability and are orchestrated by hypoxia-inducible *** stress and inflammation are critical conditions that develop under *** with changes in cellular bioenergetics,all contribute to cell ***,cell-to-cell interaction is established within the tumor such that cancer cells and the microenvironment maintain a bidirectional ***,the release of extracellular vesicles,or exosomes,represents short and long loops that can convey important information regarding invasion and *** a result,the tumor grows and its malignancy ***,one of the most lethal tumors is pancreatic *** paper reviews the most recent advances in the knowledge of how cells grow in a pancreatic tumor by adapting to *** the physiological processes that help the tumor increase its size and their regulation will be of major relevance for the treatment of this deadly tumor.

关键词： Hypoxia Cancer Tumor Pancreas Proliferation Cell survival

Runoff and losses of nutrients and herbicides under long-term conservation practices (no-till and crop rotation) in the U.S. Midwest:A variable intensity simulated rainfall approach

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International Soil and Water Conservation Research 2018年第4期6卷 265-274页

作者： Javier M.gonzalez United States Department of Agriculture Agricultural Research ServiceNational Soil Erosion Research LaboratoryWest LafayetteIN 47907USA

The U.S. Farm Bill includes conservation practices that benefit both the environment and the farmer. The USDA Conservation Effects Assessment Project (CEAP) is a multi-agency effort to assess the efficiency of conservation practices to minimize non-point source pollution. This is follow-up study of a 28-year experiment design to assess the influence of the conservation practices of no-till and crop rotation systems (corn [Zea mays]-soybean [Glycine max]), compared to chisel tillage and monocropping systems (continuous corn) on soil health and water quality. In this study, changes on soil C and N, soil water content, runoff, and losses of ammonium-N, nitrate-N, soluble reactive P (SRP), atrazine, metolachlor, and glyphosate were compared to determine the influence of no-till and corn-soybean rotation systems, relative to chisel tillage and continuous corn, on plots planted with corn using variable intensity rainfall simulations. The long-term no-till systems had a positive impact on soil C and N, soil water, runoff, and losses of ammonium-N and nitrate-N;however, no effect was observed on losses of SRP, atrazine, metolachlor, and glyphosate. The corn-soybean rotation negatively influenced, compared to the continuous corn, soil C and N, soil water content, and increased runoff and the losses of all nutrients and herbicides measured in this study. These results suggest that additional conservation practices, in conjunction with no-till and corn-soybean rotations are needed to reduce surface losses of nutrients and pesticides while improving soil health.

关键词： No-till Crop residue Nutrients Herbicides Runoff

Liver cirrhosis and diabetes:Risk factors,pathophysiology,clinical implications and management

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World Journal of Gastroenterology 2009年第3期15卷 280-288页

作者： Diego Garcia-Compean Joel Omar Jaquez-Quintana Jose Alberto gonzalez-gonzalez Hector Maldonado-Garza Department of Gastroenterology Faculty of MedicineUniversity HospitalAve Madero y GonzalitosCol Mitras CentroMonterrey 64700Mexico

About 30% of patients with cirrhosis have diabetes mellitus(DM).Nowadays,it is a matter for debate whether type 2 DM in the absence of obesity and hypertriglyceridemia may be a risk factor for chronic liver ***,which develops as a complication of cirrhosis,is known as "hepatogenous diabetes".Insulin resistance in muscular and adipose tissues and hyperinsulinemia seem to be the pathophysiologic bases of diabetes in liver *** impaired response of the islet β-cells of the pancreas and hepatic insulin resistance are also contributory ***-alcoholic fatty liver disease,alcoholic cirrhosis,chronic hepatitis C(CHC) and hemochromatosis are more frequently associated with *** resistance increases the failure of the response to treatment in patients with CHC and enhances progression of *** in cirrhotic patients may be *** diabetes is clinically different from that of type 2 DM,since it is less frequently associated with microangiopathy and patients more frequently suffer complications of *** increases the mortality of cirrhotic *** of the diabetes is complex due to liver damage and hepatotoxicity of oral hypoglycemic *** manuscript will review evidence that exists in relation to:type 2 DM alone or as part of the metabolic syndrome in the development of liver disease;factors involved in the genesis of hepatogenous diabetes;the impact of DM on the clinical outcome of liver disease;the management of DM in cirrhotic patients and the role of DM as a risk factor for the occurrence and exacerbation of hepatocellular carcinoma.

关键词： Insulin resistance Type 2 diabetes mellitus Liver cirrhosis Hepatocellular carcinoma Chronic hepatitis C

Obstructive uropathy: Overview of the pathogenesis, etiology and management of a prevalent cause of acute kidney injury

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World Journal of Nephrology 2024年第2期13卷 5-15页

作者： Xabier Pérez-Aizpurua Ramiro Cabello Benavente Gonzalo Bueno Serrano JoséMaría Alcázar Peral Blanca Gómez-Jordana Mañas Jaime Tufet i Jaumot Joaquín Ruiz de Castroviejo Blanco Felipe Osorio Ospina Carmen gonzalez-Enguita Department of Urology Hospital Universitario Fundación Jiménez DíazMadrid 28015MadridSpain

Obstructive uropathy is defined as the structural or functional interruption of urinary outflow at any level in the urinary *** is regarded as one of the most prevalent causes of acute kidney injury(AKI),accounting for 5%–10%of *** severe obstruction of the urinary tract is a potentially threatening situation for the kidneys and therefore requires prompt identification and management to relieve *** aim of the present article is to review and synthesize available evidence on obstructive uropathy,providing a clinical guideline for clinicians.A literature review on obstructive uropathy in the context of AKI was performed,focusing on the least clarified aspects regarding diagnosis and *** literature searching was conducted in English and top-level evidence articles including systematic reviews,metanalyses and large series were *** obstruction of the urinary tract is a diagnostic and therapeutical challenge that may lead to important clinical complications together with direct structural and hemodynamic damage to the *** recognition of the leading cause and its exact location is essential to ensure prompt urinary drainage together with the most suitable drainage technique selection.A multidisciplinary approach,including urologists,nephrologists,and other medical specialties,is best suited to correctly manage concomitant hemodynamic changes,fluid and electrolyte imbalances,and other related *** uropathy is one of the leading causes of *** of patients suitable for early diversion and feasibility or adequate selection of the indicated technique is sometimes challeng-ing.A thorough understanding of the physiopathology behind the development of urinary obstruction is vital for correct diagnosis and management.

关键词： Obstructive uropathy Urinary tract obstruction Obstruction of the urinary tract Acute kidney injury Urinary diversion Renal recovery

A survey of static and dynamic potential games

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Science China Mathematics 2016年第11期59卷 2075-2102页

作者： gonzalez-SANCHEZ David HERNANDEZ-LERMA Onesimo Consejo Nacional de Ciencia y Tecnología Universidad de Sonora Hermosillo 83000 Mexico Mathematics Department Centro de Investigación y de Estudios Avanzados del Instituto Politecnico National Mexico City 07000 Mexico

Potential games are noncooperative games for which there exist auxiliary functions, called potentials,such that the maximizers of the potential are also Nash equilibria of the corresponding game. Some properties of Nash equilibria, such as existence or stability, can be derived from the potential, whenever it exists. We survey different classes of potential games in the static and dynamic cases, with a finite number of players, as well as in population games where a continuum of players is allowed. Likewise, theoretical concepts and applications are discussed by means of illustrative examples.

关键词： noncooperative games potential games Nash equilibrium dynamic games Markov games differential games population games

Gravitational wave astronomy

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Frontiers of physics 2013年第6期8卷 771-793页

作者： Gabriela gonzalez Andrea Vicere Linqing Wen Department of Physics and Astronomy Louisiana State University Baton Rouge LA 70803 USA INFN Sezione di Firenze 1-50019 Sesto Fiorentino and Universitd degli Studi di Urbino 'Carlo Bo' 1-61029 Urbino Italy School of Physics The University of Western Australia 35 Stirling Hwy Crawley WA 6009 Australia

We are entering a new era of gravitational-wave astronomy. The ground-based interferometers have reached their initial design sensitivity in the audio band. Several upper limits have been set for anticipated astrophysical sources from the science data. The advanced detectors in the US and in Europe are expected to be operational around 2015. New advanced detectors are also planned in Japan and in India. The first direct detections of gravitational waves are expected within this decade. In the meanwhile, three pulsar timing array projects are forming an international collaboration to detect gravitational waves directly in the nanoHertz range using timing data from millisecond pulsars. The first direct detection of nanoHertz gravitational waves are also expected within this decade. In this paper, we review the status of current gravitational-wave detectors, possible types of sources, observational upper limits achieved, and future prospects for direct detection of gravitational waves

关键词： gravitational waves gravitational-wave detectors gravitional astronomy

Natural vegetation cover in the landscape and edge effects： differential responses of insect orders in a fragmented forest

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Insect Science 2017年第5期24卷 891-901页

作者： Ezequiel gonzalez Adriana Salvo Graciela Valladares Centro de Investigaciones Entomologicas de Cordoba IMBIV UNC CONICET FCEFyN Av. Velez Sarfield 1611 Cordoba CordobaX5000GMC Argentina

Human activities have led to global simplification of ecosystems, among which Neotropical dry forests are some of the most threatened. Habitat loss as well as edge effects may affect insect communities. Here, we analyzed insects sampled with pan traps in 9 landscapes （at 5 scales, in 100-500 m diameter circles） comprising cultivated fields and Chaco Serrano forests, at overall community and taxonomic order level. In total 7043 specimens and 456 species of hexapods were captured, with abundance and richness being directly related to forest cover at 500 m and higher at edges in comparison with forest interior. Community composition also varied with forest cover and edge^interior location. Different responses were detected among the 8 dominant orders. Collembola, Hemiptera, and Orthoptera richness and^or abundance were positively related to forest cover at the larger scale, while Thysanoptera abundance increased with forest cover only at the edge. Hymenoptera abundance and richness were negatively related to forest cover at 100 m. Coleoptera, Diptera, and Hymenoptera were more diverse and abundant at the forest edge. The generally negative influence of forest loss on insect communities could have functional consequences for both natural and cultivated systems, and highlights the relevance of forest conservation. Higher diversity at the edges could result from the simultaneous presence of forest and matrix species, although ＂resource mapping＂ might be involved for orders that were richer and more abundant at edges. Adjacent crops could benefit from forest proximity since natural enemies and pollinators are well represented in the orders showing nositive edge effects.

关键词： Chaco Serrano edge effect forest cover habitat loss insects orders