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缺铁大鼠间歇或每日补铁时铁吸收与滞留的比较

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中国实验血液学杂志 1994年第2期2卷 165-169页

作者：刘戌年 fernando e.viteri 新疆昌吉回族自治州人民医院昌吉831100 University California at Berkeley

32只雄性刚断奶SD大鼠,通过人工喂饲无或含有铁的纯合成饲料,建立缺铁与铁正常大鼠模型,使用^(59)Fe示踪法对缺铁大鼠每日补铁与每间隔3日补相等量铁的铁吸收率和滞留量进行观察对比。缺铁大鼠经每日补铁与间隔3日补铁后,动物整体铁吸... 详细信息

32只雄性刚断奶SD大鼠,通过人工喂饲无或含有铁的纯合成饲料,建立缺铁与铁正常大鼠模型,使用^(59)Fe示踪法对缺铁大鼠每日补铁与每间隔3日补相等量铁的铁吸收率和滞留量进行观察对比。缺铁大鼠经每日补铁与间隔3日补铁后,动物整体铁吸收率分别为6.8±0.5％、14.2±0.9％,铁滞留量分别为9.1±0.3mg、7.0±0.4mg,其中两组大鼠肝脏、小肠粘膜组织非血红素铁测定总值分别为4.6±0.4mg、2.2±0.3mg。结果提示:缺铁大鼠经间隔3日补铁后铁吸收率明显高于每日补铁组;铁滞留量与每日补铁组无显著差异;肝脏、小肠粘膜组织的铁负荷少于每日补铁组。

关键词：间隔补铁每日补铁 59Fe示踪法吸收滞留

A New Concept in the Control of Iron Deficiency:Community-based Preventive Supplementation of At-Risk Groups by the Weekly Intake of Iron Supplements

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Biomedical and environmental Sciences 1998年第1期11卷 46-60页

作者： fernando e. viteri(Deportment of Nutrilional Sciences and Toxicology, University ofCalifornia at Berkeley and United Nations Uliversity,Berkeley 94720, Chlifornia, USA) Department of Nutritional Sciences and Toxicology University of California at Berkeley USA.

Iron deficiency (ID), defined as an insufficient supply of iron to the cells of the body after iron reserves have been exhausted, is the most prevalent single nutritional deficiency, affecting over 2, 000 million people, mostly in the developing world. Infants, small children, adolescents and pregnant and fertile-age women are most vulnerable. Only about 50 % of people with ID develop iron deficiency anemia (IDA), since this is a late manifes tation of chronic ID. Based on the average daily iron requirement and on the rate of iron reutilization from red cell hemoglobin destruction, it can be estimated that after iron stores have been depleted, it takes about 4 months of ID erythropoiesis for adult women to have a drop in hemoglobin concentration [Hb] of 10 g/l, if the iron intake is only 70 % of requirement. IDA can be defined by a [Hb] below an appropriate cut-off point for age,sex, physiological condition and altitude above sea level, or by a [Hb] increment of morethan 10 g/l to the administration of adequate doses of iron. More than 85 % of the nutritional anemias are IDA alone, or of iron combined with folate or other nutrient deficiencies [WHO/UNICeF/UNU, 1997; Yip, 1994].

关键词： A New Concept in the Control of Iron Deficiency ACC

e-Commerce Fraud Detection Based on Machine Learning Techniques:Systematic Literature Review

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Big Data Mining and Analytics 2024年第2期7卷 419-444页

作者： Abed Mutemi fernando Bacao NOVA Information Management School(NOVA IMS) Universidade Nova de LisboaCampus de CampolideLisboa 1070-312Portugal

The e-commerce industry’s rapid growth,accelerated by the COVID-19 pandemic,has led to an alarming increase in digital fraud and associated *** establish a healthy e-commerce ecosystem,robust cyber security and anti-fraud measures are ***,research on fraud detection systems has struggled to keep pace due to limited real-world *** in artificial intelligence,Machine Learning(ML),and cloud computing have revitalized research and applications in this *** ML and data mining techniques are popular in fraud detection,specific reviews focusing on their application in e-commerce platforms like eBay and Facebook are lacking *** reviews provide broad overviews but fail to grasp the intricacies of ML algorithms in the e-commerce *** bridge this gap,our study conducts a systematic literature review using the Preferred Reporting Items for Systematic reviews and Meta-Analysis(PRISMA)*** aim to explore the effectiveness of these techniques in fraud detection within digital marketplaces and the broader e-commerce *** the current state of the literature and emerging trends is crucial given the rising fraud incidents and associated *** our investigation,we identify research opportunities and provide insights to industry stakeholders on key ML and data mining techniques for combating e-commerce *** paper examines the research on these techniques as published in the past *** the PRISMA approach,we conducted a content analysis of 101 publications,identifying research gaps,recent techniques,and highlighting the increasing utilization of artificial neural networks in fraud detection within the industry.

关键词： e-commerce Machine Learning(ML) systematic review fraud detection organized retail fraud

effect of particle Froude number on sub-grid effective drag,filtered and residual stresses in fluidized gas-particle flows

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Particuology 2024年第12期95卷 36-48页

作者： Christian C.Milioli fernando e.Milioli Department of Mechanical engineering School of Engineering of São CarlosUniversity of São Paulo13566-590São CarlosSPBrazil

Sub-grid effective drag,filtered and residual stresses in the meso-scale of gas-particle fluidized flows are intrinsically affected by underlying micro-scale conditions as well as non-local effects related to macro-scale *** this work we applied microscopic two-fluid modeling to experiment with particle Froude number in order to evaluate the impact of this micro-scale condition over the concerning meso-scale derived sub-grid *** performed highly resolved simulations in periodic domains for particle Froude numbers from 12.21 to 799.22,for a wide range of macro-scale *** were filtered and classified by ranges of meso-scale markers for the various particle Froude *** particle Froude number was found to considerably affect the structural refinement of the heterogeneous flow fields thereby directly impacting effective drag,filtered and residual *** of those parameters showed systematic behaviors in relation to particle Froude number,thereby providing sound data for new sub-grid modeling propositions.

关键词： Fluidization Gas-particle flows Two-fluid model Sub-grid analysis Multiscale analysis

Beef heifer fertility: importance of management practices and technological advancements

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Journal of Animal Science and Biotechnology 2021年第1期12卷 110-121页

作者： Sarah e.Moorey fernando H.Biase Department of Animal Science University of TennesseeKnoxvilleTNUSA Department of Animal and Poultry Sciences Virginia Polytechnic Institute and State University175 West Campus DriveBlacksburgVA 24061USA.

The development of replacement heifers is at the core of cow-calf beef production systems. In 2020, the USDA,National Agricultural Statistics Service reported 5.771 million beef heifers, 500 pounds and over, are under development for cow replacement. A compilation of data from several studies indicate that between 85% and 95% of these heifers will become pregnant in their first breeding season. Several thousands of heifers being raised for replacement may not deliver a calf on their first breeding season and result in economic losses to cow-calf producers. Many management procedures have been developed to maximize the reproductive potential of beef heifers. Such approaches include, but are not limited to the following: nutritional management for controlled weight gain, identification of reproductive maturity by physiological and morphological indicators, and the implementation of an estrous synchronization *** implementation of management strategies has important positive impact(s) on the reproductive efficiency of *** are limitations, however, because some heifers deemed ready to enter their first breeding season do not become pregnant. In parallel, genetic selection for fertility-related traits in beef heifers have not promoted major genetic gains on this particular area, most likely due to low heritability of female fertility traits in cattle. Technologies such as antral follicle counting, DNA genotyping and RNA profiling are being investigated as a means to aid in the identification of heifers of low fertility potential. To date, many polymorphisms have been associated with heifer fertility, but no DNA markers have been identified across herds. Antral follicle count is an indication of the ovarian reserve and is an indicator of the reproductive health of a heifer. We have been working on the identification of transcriptome profiles in heifers associated with pregnancy outcome. Our current investigations integrating protein-coding transcript abu

关键词： Beef cattle Cow-calf Genomics Infertility

Current and future perspectives in the management and treatment of colorectal cancer

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World Journal of Clinical Oncology 2025年第2期16卷 9-17页

作者： Sigfredo e Romero-Zoghbi evita Krumina fernando López-Campos Felipe Couñago Department of Radiation Oncology GenesisCare Talavera de la ReinaToledo 45600Spain Department of Radiation Oncology GenesisCare GuadalajaraGuadalajara 19004Spain Department of Radiation Oncology Hospital Universitario Ramón Y CajalMadrid 28034Spain Department of Radiation Oncology GenesisCare-Hospital Universitario Vithas Madrid La MilagrosaMadrid 28010Spain

In this editorial,we reviewed the article by Fadlallah et al that was recently published in the World Journal of Clinical *** article provided a comprehensive and in-depth view of the management and treatment of colorectal cancer(CRC),one of the leading causes of cancer-related morbidity and mortality *** article analyzed the therapeutic modalities and their sequencing,focusing on total neoadjuvant therapy for locally advanced rectal *** highlighted the role of immunotherapy in tumors with high microsatellite instability or deficient mismatch repair,addressing recent advances that have improved prognosis and therapeutic response in localized and metastatic *** in surgical techniques,advanced radiotherapy,and systemic agents targeting specific mutational profiles are also discussed,reflecting on how they revolutionized clinical *** tumor DNA has emerged as a promising tool for detecting minimal residual disease,prognosis,and therapeutic monitoring,solidifying its role in precision *** review emphasized the importance of technological and therapeutic advancements in improving clinical outcomes and personalizing CRC treatment.

关键词： Colorectal cancer Metastatic colorectal cancer Total neoadjuvant therapy Chemoradiotherapy Colon surgery Rectal surgery Chemotherapy Immunotherapy

Multi-conductor Line Models for Harmonic Load-flow Calculations in LV Networks with High Penetration of PV Generation

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Journal of Modern Power Systems and Clean energy 2022年第5期10卷 1288-1301页

作者： fernando M.Camilo M.e.Almeida Rui Castro V.Fernao Pires Institutode engenhariade Sistemas e Computadores Investigacao eDesenvolvimento(INESC-ID)and TecnicoUniversity of LisbonLisbonPortugal eSTSetubal Polytechnics of SetubalSetuibalPortugal

Low-voltage(LV) distribution networks are unbalanced and present loads with nonlinear behavior, which introduce harmonics in the networks. The predictable increase in photovoltaic microgeneration(PV μG) accentuates this unbalanced characteristic, as well as poses new technical problems,namely voltage rise and reverse power flow. To accurately account for the distributed PV and loads in the LV network, unbalanced three-phase power flow algorithms should be utilized,where different approaches may be used to represent lines with various degrees of accuracy. The more accurate algorithm considers the electromagnetic coupling between the line conductors,whereas the simpler algorithm represents each conductor of the line as a single-phase line with pure resistive behavior. This paper aims to analyze the influence of the line model on the load flow in a highly unbalanced LV network with a high penetration of PV production, and considers the impact of the harmonics produced by nonlinear loads. Based on the results obtained,it is possible to identify the most suitable model to be used, depending on the study to be performed. Different scenarios of PV generation and loads are addressed in this paper.

关键词： Line model nonlinear loads photovoltaic microgeneration unbalanced distribution network

Selection of micro-fabrication techniques on stainless steel sheet for skin friction

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Friction 2016年第2期4卷 89-104页

作者： S.ZHANG X.ZeNG D.T.A.MATTHeWS A.IGARTUA e.RODRIGUeZ-VIDAL J.CONTReRAS FORTeS V.SAeNZ De.viteri Laboratory for Surface Technology and Tribology Faculty of Engineering Technology University of Twente Drienerlolaan 5 Enschede 7522 NB the Netherlands Laboratory for Surface Technology and Tribology Faculty of Engineering Technology University of Twente Drienerlolaan 5 Enschede 7522 NB the NetherlandsShanghai Advanced Research Institute Chinese Academy of Sciences Shanghai 201210 China Tata Steel Research & Development Ijmuiden 1970 CA the Netherlands IK4-Tekniker C/Ignacio Goenaga 5 Eibar 20600 Spain Acerinox europa SAU Los Barrios Spain

This review gives a concise introduction to the state-of-art techniques used for surface texturing, e.g., wet etching, plasma etching, laser surface texturing (LST), 3D printing, etc. In order to fabricate deterministic textures with the desired geometric structures and scales, the innovative texturing technologies are developed and extended. Such texturing technology is an emerging frontier with revolutionary impact in industrial and scientific fields. With the help of the latest fabrication technologies, surface textures are scaling down and more complex deterministic patterns may be fabricated with desired functions, e.g., lotus effect (hydrophobic), gecko feet (adhesive), haptic tactile, etc. The objective of this review is to explore the surface texturing technology and its contributions to the applications.

关键词： microfabrication surface texturing

effect of operating conditions and potassium content on Fischer-Tropsch liquid products produced by potassium-promoted iron catalysts

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Journal of Natural Gas Chemistry 2008年第2期17卷 175-178页

作者： Francisco e.M.Farias fernando G.Sales Fabiano A.N.Fernandes Universidade Federal do Ceará Departamento de Engenharia QuímicaCampus do PiciBloco 70960455-760 Fortaleza-CEBrazil

The dependencies of Fischer-Tropsch synthesis liquid hydrocarbon product distribution on operating pressure and temperature have been studied over three potassium-promoted iron catalysts with increasing potassium molar content. The study followed an experimental planning and the results were analyzed based on surface response methodology. The effects of different operating conditions and potassium contents on the liquid product distribution were compared based on number average carbon number and dispersion. Results showed that high pressures （25 to 30 arm） favored the production of waxes that could be converted into liquid fuels through hydrocracking, while greater direct selectivity towards diesel was favored by low pressure （20 arm） using catalysts with low potassium to iron molar ratios. The liquid product distribution produced using an iron catalyst with high potassium content presented higher number-average number of carbons when compared to the distribution obtained using an iron catalyst with low potassium content.

关键词： Fischer-Tropsch synthesis liquid fuels iron-based catalyst potassium