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Glyphosa.e a. a.direct or indirect a.tiva.or of.pro-inf.a.ma.ory signa.ing a.d cognitive impa.rment

Neura. Regenera.ion Resea.ch 2024年第10期19卷 2212-2218页

作者： Yukitoshi Izumi Ka.uko a.O'Dell Cha.les f.Zorumski Depa.tment of.Psychia.ry Washington University School of MedicineSt.LouisMOUSA Ta.lor f.0}ily Institute f.r Innova.ive Psychia.ric Resea.ch Washington University School of MedicineSt.LouisMOUSA

Glyphosa.e-ba.ed herbicides a.e widely used a.ound the world, ma.ing it likely tha. most huma.s ha.e signif.ca.t exposure. Beca.se of.ha.itua. exposure, there a.e concerns a.out toxicity including neurotoxicity tha. could result in neurologica., psychia.ric, or cognitive impa.rment. We recently f.und tha. a.single injection of.glyphosa.e inhibits long-term potentia.ion, a.cellula. model of.lea.ning a.d memory, in ra. hippoca.pa. slices dissected 1 da. a.ter injection, indica.ing tha. glyphosa.e-ba.ed herbicides ca. a.ter cognitive f.nction. Glyphosa.e-ba.ed herbicides could a.versely a.f.ct cognitive f.nction either indirectly a.d/or directly. Indirectly, glyphosa.e could a.f.ct gut microbiota. a.d if.dysbiosis results in endotoxemia.lea.y gut), inf.ltra.ed ba.teria. by-products such a. lipopolysa.cha.ides could a.tiva.e pro-inf.a.ma.ory ca.ca.es. Glyphosa.e ca. a.so directly trigger pro-inf.a.ma.ory ca.ca.es. Indeed, we observed tha. a.ute glyphosa.e exposure inhibits long-term potentia.ion in ra. hippoca.pa. slices. Interestingly, direct inhibition of.long-term potentia.ion by glyphosa.e a.pea.s to be simila. to tha. of.lipopolysa.cha.ides. There a.e severa. possible mea.ures to control dysbiosis a.d neuroinf.a.ma.ion ca.sed by glyphosa.e. Dieta.y inta.e of.polyphenols, such a. quercetin, which overcome the inhibitory ef.ect of.glyphosa.e on long-term potentia.ion, could be one ef.ective stra.egy. The a.m of.this na.ra.ive review is to discuss possible mecha.isms underlying neurotoxicity f.llowing glyphosa.e exposure a. a.mea.s to identif. potentia. trea.ments.

关键词： cognitive impa.rment glyphosa.e microglia neuroinf.a.ma.ion roundup toll-like receptor 4 zinc chela.ion

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Digita. twin-a.d extended rea.ity-ba.ed telepresence f.r colla.ora.ive robot progra.ming in the 6G perspective

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Digita. Communica.ions a.d Networks 2024年第2期10卷 315-327页

作者： Da.ide Ca.a.dra.f.Ga.riele Pra.ticò a.berto Ca.na.ò Cla.dio Ca.etti f.0}rizio La.berti Politecnico di Torino Department of Control and Computer EngineeringCorso Duca Degli Abruzzi2410129TurinItaly

In the context of.Industry 4.0,a.pa.a.igm shif. f.om tra.itiona. industria. ma.ipula.ors to Colla.ora.ive Robots(CRs)is ongoing,with the la.ter serving ever more closely huma.s a. a.xilia.y tools in ma.y production *** this scena.io,continuous technologica. a.va.cements of.er new opportunities f.r f.rther innova.ing robotics a.d other a.ea. of.next-genera.ion *** exa.ple,6G could pla. a.prominent role due to its huma.-centric view of.the industria. *** pa.ticula.,its expected dependa.ility f.a.ures will pa.e the wa. f.r new a.plica.ions exploiting highly ef.ective Digita. Twin(DT)-a.d eXtended Rea.ity(XR)-ba.ed *** this work,a.novel a.plica.ion f.r the a.ove technologies a.lowing two dista.t users to colla.ora.e in the progra.ming of.a.CR is *** a.proa.h encompa.ses dema.ding da.a.f.ows(e.g.,point cloud-ba.ed strea.ing of.colla.ora.ing users a.d robotic environment),with network la.ency a.d ba.dwidth *** obta.ned by a.a.yzing this a.proa.h f.om the viewpoint of.network requirements in a.setup designed to emula.e 6G connectivity indica.e tha. the expected perf.rma.ce of.f.rthcoming mobile networks will ma.e it f.lly f.a.ible in principle.

关键词： 6G Digita. twin Telepresence Colla.ora.ive robots Industry 4.0 a.gmented rea.ity Virtua. rea.ity Point cloud strea.ing

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a.sessment the ef.ect of.Da.oxetine a.d/or a.eta.inophen in ra.s;neurochemica.s a.d oxida.ive stress bioma.kers eva.ua.ion

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Bra.n Science a.va.ces 2024年第1期10卷 57-71页

作者： Geha. S.Georgy Ibra.im M.Ibra.im La.la.Moha.ed E.a.er Ebteha. Moha.ma. f. Pha.ma.ology Depa.tment Egyptian Drug Authority(EDA)Giza P.O.29Egypt Molecula. Drug Eva.ua.ion Depa.tment Egyptian Drug Authority(EDA)Giza P.O.29Egypt Histology Depa.tment Faculty of MedicineAl-Azhar UniversityDamietta P.O.11651Egypt

Da.oxetine is a.newer a.ti-depressa.t tha. is used f.r severe f.rms of.depression via.selective serotonin reupta.e inhibition *** a.med to eva.ua.e the ef.ect of.dif.erent doses of.da.oxetine lonely or with a.eta.inophen(a.P).Seven groups of.a.bino ra.s were used where da.oxetine wa. a.ministered ora.ly a. the doses of.3,5,a.d 8 mg/kg body weight f.r a.period of.14 da.s in groups 2,4,a.d 6,***(67.5 mg/kg body weight)wa. co-a.ministered with da.oxetine(3,5,a.d 8 mg/kg body weight)f.r 14 da.s in groups 3,5 a.d 7,*** in mid a.d high dose plus a.P increa.ed body weight a.d hema.ologica. *** a.d rea.ing were declined with mid a.d high doses of.da.oxetine+a.P,contra.y to *** wa. decrea.ed with high doses of.da.oxetine+*** dose of.da.oxetine+a.P induced lowering of.serotonin a.d dopa.ine a. well a. increa.ing of.*** derived neurotrophic f.0}tor wa. decrea.ed in a.l *** stress bioma.kers were a.gmented with high dose of.da.oxetine+*** doses of.da.oxetine a.d/or a.P induced loss of.the Purkinje cell la.er a. *** high dose of.da.oxetine+a.P denotes beha.iora.,histopa.hologica. a.d neurochemica. a.tera.ions,even though no serotonin syndrome occurs.

关键词： a.eta.inophen da.oxetine neurotra.smitters oxida.ive stress bioma.kers

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Understa.ding intra.ena. ba.kf.ow: Intra.ena. pressure during ureteroscopy a.d beyond

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a.ia. Journa. of.Urology 2024年第2期11卷 139-142页

作者： Pa.le J.S.Osther Susa.ne S.Osther Ma.ia.P.Hesselholt Sof.a.Byllov Søren K.Lilda. Louise f.Øbro Helene Jung Urologica. Resea.ch Center Department of UrologyVejle Hospital(a part of Lillebaelt Hospital)University Hospital of Southern DenmarkVejleDenmark Depa.tment of.Regiona. Hea.th Resea.ch University of Southern DenmarkOdenseDenmark

The number of.ureterorenoscopic procedures f.r upper urina.y tra.t stone ma.a.ement ha. increa.ed dra.a.ica.ly during recent yea.s worldwide[1].Developments in f.exible ureteroscope a.d la.er technology ha.e ma.e it possible to successf.lly a.dress la.ger a.d more complex stone scena.ios *** the other ha.d,this mea.s tha. more a.d more pa.ients a.e exposed to the potentia. a.verse ef.ects of.ureteroscopy[2].In genera.,ureteroscopy is considered a.sa.e ***,serious complica.ions a.d even dea.hs do occur,a.d these events a.e most likely underreported[3,4].

关键词： beyond likely ureter

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a.C-sha.ed hinge f.r displa.ement ma.nif.ca.ion in MEMS rota.iona. structures

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Microsystems & Na.oengineering 2024年第1期10卷 55-66页

作者： Na.a.Ma.ika.ta.Komma.a.oina.Tef.ri Sitota. Ya.lew a.vise Ba.olini Ma.ia.f.Pa.ta.o Depa.tment of.Civil Environmental and Mechanical EngineeringUniversity of Trentovia Mesiano 7738123 TrentoItaly f.nda.ione Bruno Kessler(f.K) Microsystems Technology(MST)via S.Croce 7738122 TrentoItaly

The design,a.a.ysis,f.0}rica.ion,a.d cha.a.teriza.ion of.two distinct MEMS rota.iona. structures a.e provided;these structures include a.cla.sica. symmetrica. la.cet structure a.d a.novel symmetrica. C-sha.ed structure provided with a.tilted a.m,a.d both a.e a.tua.ed by therma. *** proposed C-sha.ed structure implemented a.curved bea. mecha.ism to enha.ce the movement delivered by the therma. *** geometrica. pa.a.eters of.our proposed device were optimized using the design of.experiment(DOE)***,the a.a.ytica. modeling ba.ed on Ca.tiglia.o’s second theorem a.d the simula.ions ba.ed on the f.nite element method(f.M)were used to predict the beha.ior of.the symmetrica. C-sha.ed structure;the results were in good a.reement with ea.h *** MEMS-ba.ed rota.iona. structures were f.0}rica.ed on silicon-on-insula.or(SOI)wa.ers using bulk microma.hining technology a.d deep rea.tive ion etching(DRIE)*** f.0}rica.ed devices underwent experimenta. cha.a.teriza.ion;our results showed tha. our proposed MEMS rota.iona. structure exhibited a.28%improvement in the delivered displa.ement compa.ed to the symmetrica. la.cet ***,the experimenta. results showed good a.reement with those obta.ned f.om numerica. *** proposed structures ha.e potentia. a.plica.ions in a.va.iety of.MEMS devices,including a.celerometers,gyroscopes,a.d resona.ors,due to their a.ility to ma.imize displa.ement a.d thus enha.ce sensitivity.

关键词： sha.ed displa.ement structures

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Resource ma.a.ement a. the network edge f.r f.dera.ed lea.ning

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Digita. Communica.ions a.d Networks 2024年第3期10卷 765-782页

作者： Silva.a.Trinda.e Luiz f.Bittencourt Nelson L.S.da.f.nseca Institute of.Computing State University of CampinasCampinasBrazil

f.dera.ed lea.ning ha. been explored a. a.promising solution f.r tra.ning ma.hine lea.ning models a. the network edge,without sha.ing priva.e user *** limited resources a. the edge,new solutions must be developed to levera.e the sof.wa.e a.d ha.dwa.e resources a. the existing solutions did not f.cus on resource ma.a.ement f.r network edge,specia.ly f.r f.dera.ed *** this pa.er,we describe the recent work on resource ma.a.e-ment a. the edge a.d explore the cha.lenges a.d f.ture directions to a.low the execution of.f.dera.ed lea.ning a. the *** such a. the discovery of.resources,deployment,loa. ba.a.cing,migra.ion,a.d energy ef.i-ciency a.e discussed in the pa.er.

关键词： Resource ma.a.ement Edge computing f.dera.ed lea.ning Ma.hine lea.ning

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Nonlinea. corrections f.r the nuclea. gluon distribution in ea.processes

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Chinese Physics C 2024年第3期48卷 52-64页

作者： G.R.Boroun B.Reza.i f.a.di Depa.tment of.Physics Razi UniversityKermanshah 67149Iran.

a. a.a.ytica. study with respect to the nonlinea. corrections f.r the nuclea. gluon distribution f.nction in the next-to-lea.ing order a.proxima.ion a. sma.l x is *** consider the nonlinea. corrections to the nuclea. gluon distribution f.nctions a. low va.ues of.x a.d Q^(2) using the pa.a.etriza.ion f.(2)(x,Q^(2))a.d the nuclea. modif.ca.ion f.0}tors obta.ned f.om the Kha.pour-Soleyma.inia.a.a.hba.-Spiesberger-Guzey *** CT18 gluon distribution is used f.r the ba.eline proton gluon density a. Q^(2)_(0)=*** discuss the beha.ior of.the gluon densities in the next-to-lea.ing order a.d the next-to-next-to-lea.ing order a.proxima.ions a. the initia. sca.e Q^(2)_(0),a. well a. the modif.ca.ions due to the nonlinea. *** f.nd tha. the QCD nonlinea. corrections a.e more signif.ca.t f.r the next-to-lea.ing order a.cura.y tha. the next-to-next-to-lea.ing order f.r light a.d hea.y *** results of.the nonlinea. GLR-MQ evolution equa.ion a.e simila. to those obta.ned with the Ra.sch-Guzey-Kla.en gluon upwa.d a.d downwa.d evolutions within the *** ma.nitude of.the gluon distribution with the nonlinea. corrections increa.es with a.decrea.e in x a.d a. increa.e in a.omic number a.

关键词： gluon distribution nonlinea. corrections light a.d hea.y nuclei low x physics

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Connections Between Induction Genera.or Ef.ect a.d Open-loop Moda. Proximity to Ca.se Sub-synchronous Oscilla.ions in Series-compensa.ed Power System

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CSEE Journa. of.Power a.d Energy Systems 2024年第3期10卷 963-973页

作者： Wenjua. Du Ya.g Wa.g H.f.Wa.g Ta. Zha. Tim Littler College of.Electrica. Engineering Sichuan UniversityChengduChina School of.Electrica. Engineering the Queen’s University of BelfastBelfastUK IEEE

The induction genera.or ef.ect(IGE)a.d the openloop moda. proximity(OLMP)a.e two dif.erent rea.ons why subsynchronous oscilla.ions(SSOs)in a.series-compensa.ed power system(SCPS)ma. *** IGE a.tributes the growing SSOs to nega.ive resista.ce,while the OLMP expla.ns the SSO mecha.ism f.om the sta.dpoint of.moda. *** this pa.er,we investiga.e the connections between the IGE a.d the OLMP through equiva.ent RLC circuit a.d open-loop moda. *** investiga.ion is conducted f.r two types of.seriescompensa.ed power systems where either a.synchronous genera.or or a.Df.G is connected a. the sending *** investiga.ion revea.s the conditions,in which the IGE a.d the OLMP ma. jointly ca.se the growing SSOs,i.e.,both the IGE a.d the OLMP ca. expla.n why the growing SSOs ***,the investiga.ion indica.es tha. the IGE a.d the OLMP ma. be tota.ly irreleva.t a.d lea. to growing SSOs *** implies tha. it is possible tha. in a.SCPS,the growing SSOs a.e only due to the IGE,a.d the OLMP is non-existent,a.d vice ***,when the growing SSOs occurs in a.SCPS,exa.ina.ion ba.ed on both the IGE a.d the OLMP should be ca.ef.lly conducted in order to f.nd if.the oscilla.ory insta.ility is due to the IGE,or the OLMP,or both of.them.

关键词： Induction genera.or ef.ect open-loop moda. proximity series compensa.ion sub-synchronous oscilla.ions

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Ra.ia.ive loss of.coherence in f.ee electrons:a.long-ra.ge qua.tum phenomenon

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Light(Science & a.plica.ions) 2024年第2期13卷 294-301页

作者： Cruz I.Vela.co Va.erio Di Giulio f.Ja.ier Ga.cía.de a.a.o ICf.-Institut de Ciencies f.toniques The Barcelona Institute of Science and Technology08860Castelldefels(Barcelona)Spain ICREa.InstitucióCa.a.a.a.de Recerca.i Estudis a.a.ça.s Passeig Lluís Companys 2308010BarcelonaSpain

Qua.tum physics rules the dyna.ics of.sma.l objects a. they intera.t over microscopic length ***,qua.tum correla.ions involving ma.roscopic dista.ces ca. be observed between enta.gled photons a. well a. in a.omic ga.es a.d ma.ter wa.es a. low *** long-ra.ge na.ure of.the electroma.netic coupling between cha.ged pa.ticles a.d extended objects could a.so trigger qua.tum phenomena.over la.ge ***,we revea. a.ma.if.sta.ion of.qua.tum mecha.ics tha. involves ma.roscopic dista.ces a.d results in a.nea.ly complete depletion of.coherence a.socia.ed with which-wa. f.ee-electron interf.rence produced by electron-ra.ia.ion coupling in the presence of.dista.t extended *** is a.ubiquitous ef.ect tha. we illustra.e through a.rigorous theoretica. a.a.ysis of.a.two-pa.h electron bea. intera.ting with a.semi-inf.nite meta.lic pla.e a.d f.nd the inter-pa.h coherence to va.ish proportiona.ly to the pa.h sepa.a.ion a. zero tempera.ure a.d exponentia.ly a. f.nite *** investiga.ed regime of.la.ge dista.ces origina.es in the coupling of.the electron to ra.ia.ive modes a.sisted by dif.ra.tion a. ma.eria. structures but without a.y involvement of.ma.eria. *** the f.nda.enta. interest of.this ma.roscopic qua.tum phenomenon,our results suggest a. a.proa.h to mea.uring the va.uum tempera.ure a.d nondestructively sensing the presence of.dista.t objects.

关键词： tempera.ure qua.tum ma.roscopic

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Inf.ow a.d outf.ow permea.ility tests in a.very sof. cla. under low stresses

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Journa. of.Rock Mecha.ics a.d Geotechnica. Engineering 2024年第8期16卷 3270-3283页

作者： J.W.S.Va.ga. f.a.B.Da.ziger f.R.Lopes T.Lunne f.dera. University of.Rio de Ja.eiro Rio de JaneiroBrazil Norwegia. Geotechnica. Institute OsloNorway

In situ inf.ow a.d outf.ow permea.ility tests with the Ba. probe a. Sa.a.uíII sof. cla. test site a.e presented.a.description of.the Ba. permea.ility test is provided,discussing its a.va.ta.es a.d shortcomings,especia.ly in the ca.e of.very sof. cla.s under low *** pressures were monitored during probe insta.la.ion a.d were f.und to be slightly lower tha. piezocone u2 pore pressures,consistent with the position of.the *** role of.f.lter tip sa.ura.ion wa. investiga.ed a.ter the usua. sa.ura.ion procedure provided a. unsa.isf.0}tory pore pressure response during probe *** show tha. the va.uum sa.ura.ion procedure provides a.equa.e response during insta.la.ion a.d increa.es the relia.ility of.the coef.icient of.permea.ility determina.ion in ea.ly *** inf.ow a.d outf.ow tests yielded simila. results,indica.ing tha. ca.ef.l execution of.the test ca. lea. to good test repea.a.ility rega.dless of.the loa.ing *** sequences of.a.terna.ed inf.ow a.d outf.ow tests ha.e yielded simila. results,indica.ing tha. soil reconsolida.ion a.d f.lter clogging were negligible in the tests *** a.e presented concerning the rela.ionship between index pa.a.eters a.d the in situ coef.icient of.permea.ility f.r Sa.a.uíII cla.,which plot outside the ra.ge of.existing da.a.a.es.

关键词： Permea.ility test Sof. cla. Ba. probe Inf.ow a.d outf.ow tests

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