检索结果-南通市图书馆

Ensemble Forecasts of Tropical Cyclone Track with Orthogonal Conditional Nonlinear Optimal Perturbations

Advances in Atmospheric Sciences 2019年第2期36卷 231-247页

作者： Zhenhua HUO Wansuo DUAN feifan zhou National Meteorological Center China Meteorological Administration State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics Institute of Atmospheric Physics Chinese Academy of Sciences University of Chinese Academy of Sciences Laboratory of Cloud-Precipitation Physics and Severe Storms Institute of Atmospheric PhysicsChinese Academy of Sciences

This paper preliminarily investigates the application of the orthogonal conditional nonlinear optimal perturbations(CNOPs)–based ensemble forecast technique in MM5(Fifth-generation Pennsylvania State University–National Center for Atmospheric Research Mesoscale Model). The results show that the ensemble forecast members generated by the orthogonal CNOPs present large spreads but tend to be located on the two sides of real tropical cyclone(TC) tracks and have good agreements between ensemble spreads and ensemble-mean forecast errors for TC tracks. Subsequently, these members reflect more reasonable forecast uncertainties and enhance the orthogonal CNOPs–based ensemble-mean forecasts to obtain higher skill for TC tracks than the orthogonal SVs(singular vectors)–, BVs(bred vectors)– and RPs(random perturbations)–based ones. The results indicate that orthogonal CNOPs of smaller magnitudes should be adopted to construct the initial ensemble perturbations for short lead–time forecasts, but those of larger magnitudes should be used for longer lead–time forecasts due to the effects of nonlinearities. The performance of the orthogonal CNOPs–based ensemble-mean forecasts is case-dependent,which encourages evaluating statistically the forecast skill with more TC cases. Finally, the results show that the ensemble forecasts with only initial perturbations in this work do not increase the forecast skill of TC intensity, which may be related with both the coarse model horizontal resolution and the model error.

关键词： ensemble forecast initial perturbation conditional nonlinear optimal perturbation tropical cyclone

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Possible Sources of Forecast Errors Generated by the Global/Regional Assimilation and Prediction System for Landfalling Tropical ***Ⅰ:Initial Uncertainties

引用

Advances in Atmospheric Sciences 2016年第7期33卷 841-851页

作者： feifan zhou Munehiko YAMAGUCHI Xiaohao QIN Laboratory of Cloud-Precipitation Physics and Severe Storms Institute of Atmowheric PhysicsChinese Academy of SciencesBeijing 100029 Meteorological Research Institute of the Japan Meteorological Agency Tsukuba 305-0052Japan State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029

This paper investigates the possible sources of errors associated with tropical cyclone （TC） tracks forecasted using the Global/Regional Assimilation and Prediction System （GRAPES）. The GRAPES forecasts were made for 16 landfaIling TCs in the western North Pacific basin during the 2008 and 2009 seasons, with a forecast length of 72 hours, and using the default initial conditions （＂initials＂, hereafter）, which are from the NCEP-FNL dataset, as well as ECMWF initials. The forecasts are compared with ECMWF forecasts. The results show that in most TCs, the GRAPES forecasts are improved when using the ECMWF initials compared with the default initials. Compared with the ECMWF initials, the default initials produce lower intensity TCs and a lower intensity subtropical high, but a higher intensity South Asia high and monsoon trough, as well as a higher temperature but lower specific humidity at the TC center. Replacement of the geopotential height and wind fields with the ECMWF initials in and around the TC center at the initial time was found to be the most efficient way to improve the forecasts. In addition, TCs that showed the greatest improvement in forecast accuracy usually had the largest initial uncertainties in TC intensity and were usually in the intensifying phase. The results demonstrate the importance of the initial intensity for TC track forecasts made using GRAPES, and indicate the model is better in describing the intensifying phase than the decaying phase of TCs. Finally, the limit of the improvement indicates that the model error associated with GRAPES forecasts may be the main cause of poor forecasts of landfalling TCs. Thus, further examinations of the model errors are required.

关键词： tropical cyclone track forecast error diagnosis Global/Regional Assimilation and Prediction System initialuncertainty

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The Impact of Horizontal Resolution on the CNOP and on Its Identified Sensitive Areas for Tropical Cyclone Predictions

引用

Advances in Atmospheric Sciences 2012年第1期29卷 36-46页

作者： zhou feifan MU Mu Laboratory of Cloud-Precipitation Physics and Severe Storms Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029 Key Laboratory of Ocean Circulation and Wave Institute of OceanologyChinese Academy of SciencesQingdao 266071

In this study, the ilnpacts of horizontal resolution on the conditional nonlinear optimal perturbation （CNOP） and on its identified sensitive areas were investigated for tropical cyclone predictions. Three resolutions, 30 km, 60 km, and 120 kin, were studied for three tropical cyclones, TC Mindulle （2004）, TC Meari （2004）, and TC Matsa （2005）. Results show that CNOP may present different structures with different resolutions, and the major parts of CNOP become increasingly localized with increased horizontal resolution. CNOP produces spiral and baroclinic structures, which partially account for its rapid amplification. The differences in CNOP structures result in different sensitive areas, but there are common areas for the CNOP-identified sensitive areas at various resolutions, and the size of the common areas is different from case to case. Generally, the forecasts benefit more from the reduction of the initial errors in the sensitive areas identified using higher resolutions than those using lower resolutions. However, the largest improvement of the forecast can be obtained at the resolution that is not the highest for some cases. In addition, the sensitive areas identified at lower resolutions are also helpful for improving the forecast with a finer resolution, but the sensitive areas identified at the same resolution as the forecast would be the most beneficial.

关键词： horizontal resolution CNOP sensitive area TC prediction

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Possible Sources of Forecast Errors Generated by the Global/Regional Assimilation and Prediction System for Landfalling Tropical Cyclones. Part Ⅱ: Model Uncertainty

引用

Advances in Atmospheric Sciences 2018年第10期35卷 1277-1290页

作者： feifan zhou Wansuo DUAN He ZHANG Munehiko YAMAGUCHI Laboratory of Cloud-Precipitation Physics and Severe Storms Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China International Center for Climate and Environment Sciences(ICCES) Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Meteorological Research Institute of the Japan Meteorological Agency Tsukuba 305-0052Japan University of Chinese Academy of Sciences Beijing 100049China

This paper investigates the possible sources of errors associated with tropical cyclone(TC) tracks forecasted using the Global/Regional Assimilation and Prediction System(GRAPES). In Part I, it is shown that the model error of GRAPES may be the main cause of poor forecasts of landfalling TCs. Thus, a further examination of the model error is the focus of Part *** model error as a type of forcing, the model error can be represented by the combination of good forecasts and bad forecasts. Results show that there are systematic model errors. The model error of the geopotential height component has periodic features, with a period of 24 h and a global pattern of wavenumber 2 from west to east located between 60?S and 60?N. This periodic model error presents similar features as the atmospheric semidiurnal tide, which reflect signals from tropical diabatic heating, indicating that the parameter errors related to the tropical diabatic heating may be the source of the periodic model error. The above model errors are subtracted from the forecast equation and a series of new forecasts are made. The average forecasting capability using the rectified model is improved compared to simply improving the initial conditions of the original GRAPES model. This confirms the strong impact of the periodic model error on landfalling TC track forecasts. Besides, if the model error used to rectify the model is obtained from an examination of additional TCs, the forecasting capabilities of the corresponding rectified model will be improved.

关键词： GRAPES error diagnosis model uncertainty predictability tropical cyclone

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

SINGLE CELL IMAGING OF BAX TRANSLOCATION DURING APOPTOSIS INDUCED BY PHOTOFRIN-PDT

引用

Journal of Innovative Optical Health Sciences 2009年第2期2卷 209-214页

作者： feifan zhou DA XING WEI R.CHEN MOE Key Laboratory of Laser Life Science&Institute of Laser Life Science South China Normal University Guangzhou 510631China Department of Engineering and Physics College of Mathematics and Science University of Central OklahomaEdmondOklahoma 73034USA

Apoptosis is an important cellular event that plays a key role in the therapy of many *** mechanism of the initiation and regulation of photodynamic therapy(PDT)–induced apoptosis is *** previous study found that Photofrin was localized primarily in mitochondria,the primary targets of *** key role of Bax in the mitochondria-mediated apoptosis has been demonstrated in many *** order to determine the role of Bax in the mitochondrion-mediated apoptosis induced by Photofrin-PDT,we used the GFP-Bax plasmid to monitor the dynamics of Bax activation after PDT *** laser scanning confocal microscopy,we found that Bax did not translocate from the cytosol to mitochondria when the mitochondrial membrane potential(∆Ψm)disappeared,measured by ***,for Photofrin-PDT,the commitment to cell death is independent of Bax activation.

关键词： Photofrin-photodynamic therapy mitochondria-mediated apoptosis Bax activation translocation.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Photonics immunotherapy-A novel strategy for cancer treatment

引用

Journal of Innovative Optical Health Sciences 2016年第1期9卷 1-11页

作者： feifan zhou Robert E.Nordquist Wei R.Chen Biophotonics Research Laboratory Center for Interdisciplinary Biomedical Education Research College of Mathematics and Science University of Central Oklahoma Edmond Oklahoma 73034 USA Immunophotonics Inc. St.LouisMissouri 63108USA

Photonics immunotherapy is a novel cancer treatment strategy that combines local phototherapy and *** is a noninvasive or minimally invasive therapeutic strategy for local treatment of cancer,which can destroy tumor cells and release tumor antigens,inducing an in situ antitumor immune ***,including the use of antibodies,vaccines,immunoadjuvants and cytokines,when combined with phototherapy,could bring a synergistic effect to stimulate a host immune response that effectuates a long-term antitumor *** review will focus on the development of photonics immunotherapy and its systemic antitumor immunological effects.

关键词： Photonics immunotherapy cancer phototherapy immunotherapy immune response

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Interstitial photoacoustic technique and computational simulation for temperature distribution and tissue optical properties in interstitial laser photothermal interaction

引用

Journal of Innovative Optical Health Sciences 2018年第1期11卷 47-56页

作者： Zhifang Li Haiyu Chen feifan zhou Hui Li Wei R.Chen College of Photonic and Electronic Engineering Fujian Normal University Fujian Provincial Key Laboratory of Photonic Technology Key Laboratory of Optoelectronic Science and Technology for Medicine Ministry of EducationFuzhouFujian 350007P.R.China Department of Cardiovascular Surgery Fujian Provincial Hospital Fujian Medical UniversityFuzhouFujian 350000P.R.China Biophotonics Research Laboratory Center for Interdisciplinary Biomedical Education and Research University of Central Oklahoma EdmondOklahoma 73034USA

Interstitial laser immunotherapy(ILIT)is designed to use photothermal and immunological inter-actions for treatment of metastatic *** photothermal ffect is crucial in inducing anti-tumorimmune responses in the *** temperature and tssue optical properties are important factorsin this *** this study,a device combining interstitial photoacoustic(PA)technique andinterstitial laser photothermal interaction is *** with computational simulation,thisdevice was designed to determine temperature distributions and tissue optical properties during *** were performed usinger-ivoFporcine liver *** results demonstratedthat interstitial PA signal amplitude was linearly dependent on tisue temperature in the tempera-ture ranges of 20-60℃,as wll as 65-80℃,with a dfferent slope,due to the change of tissue *** the directly measured temperature in the tissue around the interstitial optical fiberdiffusion tip for calibration,the theoretical temperature distribution predicted by the bioheatequation was used to extract optical properties of ***,the three-dimensional temperature distribution was simulated to guide tumor destruction and immunological stimulation,Thus,thisnovel device and method could be used for monitoring and controlling ILIT for cancer treatment.

关键词： Photoacoustic imaging photothermal effects temperature

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Observations of intracellular second-harmonic generation imaging in black phosphorus nanosheets

引用

Journal of Innovative Optical Health Sciences 2021年第2期4卷 11-18页

作者： Xiao Peng Yiwan Song Zheng Peng Kaixuan Nie Hao Liu Yingxin zhou feifan zhou Yufeng Yuan Jun Song Junle Qu Center for Biomedical Optics and Photonics(CBOP)&College of Physics and Optoelectronic Engineering Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province Shenzhen University Shenzhen 518060P.R.China

Functionalized black phosphorus(BP)nanosheets have been considered as promising nanoagents in cancer therapy due to their excellent photothermal conversion ***,it is still difficult to visually monitor the dynamic localization of BP nanoagents in cancer *** this paper,we systematically studied the second-harmonic generation(SHG)signals originating from exfoliated BP ***,under the excitation of a high frequency pulsed laser at 950 nm,the SHG signals of BP nanosheets in vitro are almost undetectable because of their poor ***,the intracellular SHG signals from BP nanosheets could be measured by in vivo optical imaging due to the efficient enrichment of living HeLa ***,the SHG signal intensity from BP nanosheets increases with the prolonged incubation *** can be expected that the BP nanosheets could be a promising intracellular SHG nanoprobe employed for visually in vivo biomedical imaging in practical cancer photothermal therapy(PIT).

关键词： Second harmonic generation nanoprobe black phosphorus nanosheets in vivo im-aging HeLa cells visual monitoring

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Characterization of cerebrovascular changes in Alzheimer's disease mice by photoacoustic imaging

引用

Journal of Innovative Optical Health Sciences 2024年第6期17卷 29-40页

作者： Xi Li Zhongyang Zhang Hua Shi feifan zhou Key Laboratory of Biomedical Engineering of Hainan Province School of Biomedical Engineering Hainan University Sanya 572025P.R.China

The cerebral vasculature plays a significant role in the development of Alzheimer's disease(AD),however,the specific association between them remains *** this paper,based on the benefits of photoacoustic imaging(PAI),including label-free,high-resolution,in vivo imaging of vessels,we investigated the structural changes of cerebral vascular in wild-type(WT)mice and AD mice at different ages,analyzed the characteristics of the vascular in different brain regions,and correlated vascular characteristics with cognitive *** results showed that vascular density and vascular branching index in the cortical and frontal regions of both WT and AD mice decreased with ***,vascular lacunarity increased with age,and the changes in vascular structure were more pronounced in AD *** trend of vascular dysfunction aligns with the worsening cognitive dysfunction as the disease ***,we utilized in vivo PAI to analyze the changes in vascular structure during the progression of AD,elucidating the spatial and temporal correlation with cognitive impairment,which will provide more intuitive data for the study of the correlation between cerebrovascular and the development of AD.

关键词： Photoacoustic imaging Alzheimer's disease cerebrovascular vascular network cognitive impairment.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hydrophobic aerogel-modified hemostatic gauze with thermal management performance

引用

Bioactive Materials 2023年第8期26卷 142-158页

作者： Xiaoli Jia Chao Hua Fengbo Yang Xiaoxiao Li Peng Zhao feifan zhou Yichi Lu Hao Liang Malcolm Xing Guozhong Lyu Engineering Research Center of the Ministry of Education for Wound Repair Technology Jiangnan UniversityAffiliated Hospital of Jiangnan UniversityWuxi214000China Wuxi School of Medicine Jiangnan UniversityWuxi214000China Medical School of Nantong University Nantong226019China Nanjing University of Traditional Chinese Medicine Nanjing210023China Changhai Clinical Research Unit Shanghai Changhai HospitalNaval Medical UniversityShanghai200433China Department of Mechanical Engineering University of ManitobaWinnipegR3T 2N2Canada

Current hemostatic agents or dressings are not efficient under extremely hot and cold environments due to deterioration of active ingredients,water evaporation and ice crystal *** address these challenges,we engineered a biocompatible hemostatic system with thermoregulatory properties for harsh conditions by combining the asymmetric wetting nano-silica aerogel coated-gauze(AWNSA@G)with a layer-by-layer(LBL)*** AWNSA@G was a dressing with a tunable wettability prepared by spraying the hydrophobic nano-silica aerogel onto the gauze from different *** hemostatic time and blood loss of the AWNSA@G were 5.1 and 6.9 times lower than normal gauze in rat’s injured femoral artery ***,the modified gauze was torn off after hemostasis without rebleeding,approximately 23.8 times of peak peeling force lower than normal *** the LBL structure,consisting of the nano-silica aerogel layer and a n-octadecane phase change material layer,in both hot(70℃)and cold(-27℃)environments,exhibited dual-functional thermal management and maintained a stable internal *** further verified our composite presented superior blood coagulation effect in extreme environments due to the LBL structure,the pro-coagulant properties of nano-silica aerogel and unidirectional fluid pumping of AWNSA@*** work,therefore,shows great hemostasis potential under normal and extreme temperature environments.

关键词： Hydrophobic hemostasis Thermal management Hydrophobic methyl modified nano-silica aerogel Harsh environments Unidirectional fluid pumping

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：