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Validation of serum tumor biomarkers in predicting advanced cystic mucinous neoplasm of the pancreas

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World Journal of Gastroenterology 2021年第6期27卷 501-512页

作者： Li-Qi Sun Li-Si Peng Jie-Fang Guo fei jiang Fang Cui Hao-Jie Huang Zhen-Dong Jin Department of Gastroenterology Changhai HospitalSecond Military Medical UniversityShanghai 200433China

BACKGROUND Early detection of advanced cystic mucinous neoplasms[(A-cMNs),defined as high-grade dysplasia or malignancy]of the pancreas is of great *** a simple and feasible detection method,serum tumor markers(STMs)may be used to predict advanced intraductal papillary mucinous neoplasms(IPMNs)and mucinous cystic neoplasms(MCNs).However,there are few studies on the usefulness of STMs other than carbohydrate antigen(CA)19-9 for early detection of *** To study the ability of five STMs-CA19-9,carcinoembryonic antigen(CEA),CA125,CA724,and CA242 to predict A-cMNs and distinguish IPMNs and *** We mainly measured the levels of each STM in patients pathologically diagnosed with *** mean levels of STMs and the number of A-cMN subjects with a higher STM level than the cutoff were compared respectively to identify the ability of STMs to predict A-cMNs and distinguish MCNs from IPMNs.A receiver operating characteristic curve with the area under curve(AUC)was also created to identify the performance of the five *** A total of 187 patients with cMNs were identified and 72 of them showed *** found that CA19-9 exhibited the highest sensitivity(SE)(54.2%)and accuracy(76.5%)and a moderate ability(AUC=0.766)to predict *** predicting high-grade dysplasia IPMNs,the SE of CA19-9 decreased to 38.5%.The ability of CEA,CA125,and CA724 to predict A-cMNs was low(AUC=0.651,0.583,and 0.618,respectively).The predictive ability of CA242 was not *** combination of STMs improved the SE to 62.5%.CA125 may be specific to the diagnosis of advanced *** CA19-9 has a moderate ability,and CEA,CA125,and CA724 have a low ability to predict *** combination of STM testing could improve SE in predicting A-cMNs.

关键词： Serum tumor markers Diagnosis Advanced cystic mucinous neoplasms Mucinous cystic neoplasms Intraductal papillary mucinous neoplasms

Correction to: The nucleocapsid protein of rice stripe virus in cell nuclei of vector insect regulates viral replication

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Protein & Cell 2021年第12期12卷 971-975页

作者： Wan Zhao Junjie Zhu Hong Lu Jiaming Zhu fei jiang Wei Wang Lan Luo Le Kang Feng Cui State Key Laboratory of Integrated Management of Pest Insects and Rodents Institute of ZoologyChinese Academy of SciencesBeijing 100101China CAS Center for Excellence in Biotic Interactions University of Chinese Academy of SciencesBeijing 100049China

In the original publication of the article the fill color and the border color of the histograms in Fig.3A(dsGFP and dsIMPal)and Fig.3B were ***,the schematic plot of the N fragment of NP in Fig.2D was not clear *** c... 详细信息

关键词： enough correct

Tensile mechanical analysis of anisotropy and velocity dependence of the spinal cord white matter:a biomechanical study

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Neural Regeneration Research 2021年第12期16卷 2557-2562页

作者： Norihiro Nishida Itsuo Sakuramoto Yoshihiro Fujii Rudolf Yoga Hutama fei jiang Junji Ohgi Yasuaki Imajo Hidenori Suzuki Masahiro Funaba Xian Chen Takashi Sakai Department of Orthopedic Surgery Yamaguchi University Graduate School of MedicineMinami-KogushiUbeYamaguchiJapan Department of Mechanical and Electrical Engineering National Institute of Technology Tokuyama CollegeGakuendaiShunanYamaguchiJapan Faculty of Engineering Yamaguchi UniversityTokiwadai UbeYamaguchiJapan

In spinal cord injuries,external forces from various directions occur at various ***,it is important to physically evaluate whether the spinal cord is susceptible to damage and an increase in internal stress for external *** hypothesized that the spinal cord has mechanical features that vary under stress depending on the direction and velocity of ***,it is difficult to perform experiment because the spinal cord is very *** are no reports on the effects of multiple external *** this study,we used bovine spinal cord white matter to test and analyze the anisotropy and velocity dependence of the spinal ***-vertical,tensile-parallel,shear-vertical,and shear-parallel tests were performed on the white matter in the fibrous direction(cranial to caudal).Strain rate in the experiment was 0.1,1,10,and 100/*** calculated the Young’s modulus of the spinal *** of the tensile and shear tests revealed that stress tended to increase when external forces were applied parallel to the direction of axon fibers,such as in tensile-vertical and shear-vertical ***,external forces those tear against the fibrous direction and vertically,such as in tensile-parallel and shear-parallel tests,were less likely to increase stress even with increased *** found that the spinal cord was prone to external forces,especially in the direction of the fibers,and to be under increased stress levels when the velocity of external forces *** these results,we confirmed that the spinal cord has velocity dependence and *** Institutional Animal Care and Use Committee of Yamaguchi University waived the requirement for ethical approval.

关键词： anisotropy dependence external force mechanistic analysis spinal cord injury straining rate stress velocity dependence white matter

Effect of hydrothermal temperature on the optical properties of hydrochar-derived dissolved organic matter and their interactions with copper(II)

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Biochar 2024年第1期6卷 1143-1156页

作者： Licheng Ji Zhongpu Yu Qi Cao Xiangyang Gui Xingjun Fan Chengcheng Wei fei jiang Jie Wang Fanbin Meng feiyue Li Jianfei Wang College of Resources and Environment Science Anhui Science and Technology UniversityFengyang 233100China. School of Environmental Science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China. Anhui Province Agricultural Waste Fertilizer Utilization and Cultivated Land Quality Improvement Engineering Research Center Chuzhou 233100China.

Hydrothermal carbonization(HTC)has been regarded as a promising technique for turning wet biomass into hydrochar due to its low energy consumption,low exhaust gas emissions,*** addition,hydrochar is an important source of dissolved organic matter(DOM),which plays a crucial part in the migration and destiny of pollutants in the environmental ***,there are limited studies that focus on the factors that influence the formation of DOM in hydrochar,such as hydrothermal ***,the current study comprehensively characterized the optical properties of DOM within hydrochar derived from sawdust(HDOM)under different hydrothermal temperatures(150-300℃)by Ultraviolet-visible(UV-Vis)and fluorescence spectroscopy,as well as its complexation characteristic with Cu(II).The findings revealed that the organic carbon content of HDOM reached a peak of 37.3 mg L^(−1)when the temperature rose to 240℃and then decreased as the temperature ***-Vis spectroscopy analysis showed that the absorption capacity of HDOM at 275 nm increases with temperature and reaches a maximum value at 240℃,indicating that high temperature promotes the formation of monocyclic aromatic *** temperature enhances the aromaticity,hydrophobicity,and humification degree of HDOM,thus improving its stability and *** E3/E4 ratios are all greater than 3.5,confirming that the main component of HDOM is fulvic acid,which corresponds to 3D-EEM and Pearson’s correlation coefficient *** humification index(HIX)of HDOM increased with the rise in hydrothermal temperature(150-240℃),as observed by the three-dimensional excitation-emission matrix spectroscopy(3D-EEMs).After reaching its peak at 240℃,the HIX value gradually dropped in line with the trend of the DOC ***,the bioavailability(BIX)value of DOM was all high and greater than 1,indicating all the HDOM are readily *** microbial humic substances(C1 and C4),a humic-like substance(C2),and a

关键词： Hydrochar Hydrothermal temperature Dissolved organic matter EEM-PARAFAC Metal complex

Concentration Insensitive Supramolecular Polymerization Enabled by Kinetically Interlocking Multiple-Units Strategy

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CCS Chemistry 2019年第3期1卷 296-303页

作者： Jiezhong Shi Haoyang Jia Hao Chen Xi Wang jiang-fei Xu Weibin Ren jiang Zhao Xin Zhou Yuanchen Dong Dongsheng Liu Key Laboratory of Organic Optoelectronics&Molecular Engineering of the Ministry of Education Department of ChemistryTsinghua UniversityBeijing 100084China School of Physical Sciences University of Chinese Academy of ScienceBeijing 100049China Institute of Chemistry Chinese Academy of SciencesBeijing 100190China

We proposed and demonstrated a kinetically interlocking multiple-units supramolecular polymer-ization *** rationally designed multi-ple-units monomers,the degree of polymerization(X w)detected was more than 50 with a ... 详细信息

关键词： DNA supramolecular polymerization kinetically interlocking multiple units concentration insensitive

Monofunctionalized pillar [5] arene-based stable [1] pseudorotaxane

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Chinese Chemical Letters 2015年第7期26卷 843-846页

作者： Cai-Li Sun jiang-fei Xu Yu-Zhe Chen Li-Ya Niu Li-Zhu Wu Chen-Ho Tung Qing-Zheng Yang Key Laboratory of Photochemical Conversion and Optoelectronic Materials Technical Institute of Physics and Chemistry Chinese Academy of Sciences College of Chemistry Beijing Normal University University of the Chinese Academy of Sciences

We reported a new monofunctionalized pillar[5]arene bearing imidazolium moiety that formed stable [1]pseudorotaxane even at high concentration （100 mmol/L） in chloroform. The self-assembly was detailed investigated by multiple methods, including varying concentration 1H NMR, 2D COSY NMR, 2D NOESY NMR, viscosity measurements, 2D DOSY NMR, and HR-ESI-MS analysis. [llRotaxane was obtained efficiently through photo thiol-ene reaction which further confirmed the formation of [l]pseudorotaxane.

关键词： PillarareneSelf-assembly[ 1 ]pseudorotaxanesThinl-ene reaction

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基于脉冲同步的混沌雷达信号延迟方法

宇航学报 2007年第2期28卷 484-488页

作者：蒋飞刘中南京理工大学电子工程系南京210094

提出一种基于脉冲同步技术的混沌雷达信号延迟方法。该方法首先对混沌信号进行滤波;然后对滤波输出进行采样量化,采用数字技术延迟实现量化的信号;最后通过脉冲同步系统来恢复原信号,实现混沌信号的延迟。文章给出了方法的系统实现结构... 详细信息

提出一种基于脉冲同步技术的混沌雷达信号延迟方法。该方法首先对混沌信号进行滤波;然后对滤波输出进行采样量化,采用数字技术延迟实现量化的信号;最后通过脉冲同步系统来恢复原信号,实现混沌信号的延迟。文章给出了方法的系统实现结构,并发展了一个新的脉冲同步方法。通过计算最大条件Lyapunov指数,研究了滤波器带宽和最小采样频率之间的关系并讨论了采样和量化对系统性能的影响。仿真结果表明本文方法的有效性。

关键词：延迟脉冲同步条件Lyapunov指数混沌雷达滤波

Temperature effect on shear behavior of ore-backfill coupling specimens at various shear directions

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Journal of Central South University 2021年第10期28卷 3173-3189页

作者： jiang fei-fei ZHOU Hui SHENG Jia LI Xiang-dong KOU Yong-yuan State Key Laboratory of Geomechanics and Geotechnical Engineering Institute of Rock and Soil MechanicsChinese Academy of SciencesWuhan 430071China University of Chinese Academy of Sciences Beijing 100049China National Engineering Research Center for Metal Mining Changsha Institute of Mining Research Co.Ltd.Changsha 410012China School of Resource&Environment and Safety Engineering Hunan University of Science and TechnologyXiangtan 411201China Jinchuan Group Co. Ltd.Jinchang 737104China

Understanding the temperature effect on shear behavior of the ore-backfill coupling structure is critical for the safety and stability of backfill stope under the condition of high horizontal stress in deep *** shear tests were carried out on the cemented rod-mill sand backfill(CRB)and ore-CRB(OCRB)coupling specimens at various temperatures(20,40 and 60°C).The shear behavior and AE characteristic parameters of OCRB at different shear directions were compared and *** results show that the temperature effect on the shear performance of CRB mainly depends on the characteristics of microstructures and main mineral phases;the performance of CRB at 40°C is relatively good;the shear deformation of OCRB has one more“peak fluctuation stage”than CRB and has a good correlation with AE characteristic *** temperature can positively or negatively impact the shear strength of OCRB,depending on the temperature and shear direction;the shear performance of OCRB along the axis direction(D1)is significantly better than that perpendicular to the axis direction(D2).The co-bearing capacity of the ore-backfill coupling structure(i.e.,stopes)is closely related to the ambient temperature and principal stress orientation.

关键词： cemented backfill ore-backfill temperature shear direction shear strength AE energy

Global Terrestrial Ecosystem Carbon Flux Inferred from TanSat XCO_(2)Retrievals

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Journal of Remote Sensing

Journal of Remote Sensing 2022年第1期2022卷 299-310页

作者： Hengmao Wang fei jiang Yi Liu Dongxu Yang Mousong Wu Wei He Jun Wang Jing Wang Weimin Ju Jing MChen jiangsu Provincial Key Laboratory of Geographic Information Science and Technology International Institute for Earth System ScienceNanjing UniversityNanjing 210023China jiangsu Center for Collaborative Innovation in Geographical Information Resource Development and Application Nanjing 210023China Institute of Atmospheric Physics Chinese Academy of SciencesBeijing 100029China Department of Geography University of TorontoTorontoOntarioCanada M5S3G3

TanSat is China’s first greenhouse gases observing *** recent years,substantial progresses have been achieved on retrieving column-averaged CO_(2)dry air mole fraction(XCO_(2)).However,relatively few attempts have been made to estimate terrestrial net ecosystem exchange(NEE)using TanSat XCO_(2)*** this study,based on the GEOS-Chem 4D-Var data assimilation system,we infer the global NEE from April 2017 to March 2018 using TanSat XCO_(2).The inversion estimates global NEE at−3.46 PgC yr^(-1),evidently higher than prior estimate and giving rise to an improved estimate of global atmospheric CO_(2)growth ***,our inversion greatly increases the carbon uptakes in northern mid-to-high latitudes and significantly enhances the carbon releases in tropical and southern lands,especially in Africa and India *** increase of posterior sinks in northern lands is mainly attributed to the decreased carbon release during the nongrowing season,and the decrease of carbon uptakes in tropical and southern lands basically occurs throughout the *** against independent CO_(2)observations and comparison with previous estimates indicate that although the land sinks in the northern middle latitudes and southern temperate regions are improved to a certain extent,they are obviously overestimated in northern high latitudes and underestimated in tropical lands(mainly northern Africa),*** results suggest that TanSat XCO_(2)retrievals may have systematic negative biases in northern high latitudes and large positive biases over northern Africa,and further efforts are required to remove bias in these regions for better estimates of global and regional NEE.

关键词： estimates remove attributed