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Understanding the Recovery of the Intervertebral Disc:A Comprehensive Review of In Vivo and In Vitro Studies

Journal of Bionic Engineering 2024年第4期21卷 1919-1948页

作者： faten feki Fahmi Zaïri Abderrahman Tamoud Melissa Moulart Rym Taktak Nader Haddar Fahed Zaïri Sfax University ENISMaterials Engineering and Environment Laboratory3038SfaxTunisia University of Lille IMT Nord EuropeJUNIAUniversity of ArtoisULR 4515-LGCgELaboratoire de Génie Civil et geo-Environnement59000LilleFrance PrediTwins Lab 59000LilleFrance Japet Medical Device 59000LilleFrance Sfax University ENISLaboratory of Advanced Materials3038SfaxTunisia Ramsay Générale de Santé Hôpital PrivéLe Bois59000LilleFrance

Within the consistent daily rhythm of human life,intervertebral discs endure a variety of complex loads beyond the influences of gravity and muscle forces,leading to significant morphological changes(in terms of volume,area,and height)as well as biomechanical alterations,including an increase in disc stiffness and a decrease in intradiscal ***,the discs demonstrate an ability to regain their original morphological and biomechanical characteristics after a period of nocturnal *** preservation of normal disc function is critically dependent on this recovery phase,which serves to forestall premature disc *** phenomenon of disc recovery has been extensively documented through numerous in vivo studies employing advanced clinical techniques such as Magnetic Resonance Imaging(MRI),stadiometry,and intradiscal pressure ***,the findings from in vitro studies present a more complex picture,with reports varying between full recovery and only partial recuperation of the disc ***,research focusing on degenerated discs in vitro has shed light on the quantifiable impact of degeneration on the disc ability to *** dynamics within the disc are considered a primary factor in recovery,yet the disc intricate multiscale structure and its viscoelastic properties also play key *** elements interact in complex ways to influence the recovery mechanism,particularly in relation to the overall health of the *** objective of this review is to collate,analyze,and critically evaluate the existing body of in vivo and in vitro research on this topic,providing a comprehensive understanding of disc recovery *** understanding offers a blueprint for future advancements in medical treatments and bionic engineering solutions designed to mimic,support,and enhance the natural recovery processes of intervertebral discs.

关键词： Intervertebral disc Recovery In vivo vs.in vitro studies Degeneration Viscoelastic effects Fluid dynamics

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Image Fusion Using Wavelet Transformation and XGboost Algorithm

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Computers, Materials & Continua 2024年第4期79卷 801-817页

作者： Shahid Naseem Tariq Mahmood Amjad Rehman Khan Umer Farooq Samra Nawazish faten S.Alamri Tanzila Saba Department of Information Sciences Division of S&TUniversity of EducationLahore54770Pakistan Artificial Intelligence and Data Analytics(AIDA)Lab CCIS Prince Sultan UniversityRiyadh11586Saudi Arabia Faculty of Information Sciences University of EducationVehari CampusVehari61100Pakistan Department of Computer Science University of Engineering and TechnologyTaxila47050Pakistan Department of Mathematical Sciences College of SciencePrincess Nourah Bint Abdulrahman UniversityRiyadh84428Saudi Arabia

Recently,there have been several uses for digital image *** fusion has become a prominent application in the domain of imaging *** create one final image that provesmore informative and helpful compared to the original input images,image fusion merges two or more initial images of the same *** fusion aims to produce,enhance,and transform significant elements of the source images into combined images for the sake of human visual *** fusion is commonly employed for feature extraction in smart robots,clinical imaging,audiovisual camera integration,manufacturing process monitoring,electronic circuit design,advanced device diagnostics,and intelligent assembly line robots,with image quality varying depending on *** research paper presents various methods for merging images in spatial and frequency domains,including a blend of stable and curvelet transformations,everageMax-Min,weighted principal component analysis(PCA),HIS(Hue,Intensity,Saturation),wavelet transform,discrete cosine transform(DCT),dual-tree Complex Wavelet Transform(CWT),and multiple wavelet *** fusion methods integrate data from several source images of an identical target,thereby enhancing information in an extremely efficient *** precisely,in imaging techniques,the depth of field constraint precludes images from focusing on every object,leading to the exclusion of certain *** tackle thess challanges,a very efficient multi-focus wavelet decomposition and recompositionmethod is *** use of these wavelet decomposition and recomposition techniques enables this method to make use of existing optimized wavelet code and filter *** simulated outcomes provide evidence that the suggested approach initially extracts particular characteristics from images in order to accurately reflect the level of clarity portrayed in the original *** study enhances the performance of the eXtreme Gradient Boosting(XGBoos

关键词： Image fusion max-min average CWT XGBoost DCT inclusive innovations spatial and frequency domain

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Outsmarting Android Malware with Cutting-Edge Feature Engineering and Machine Learning Techniques

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Computers, Materials & Continua 2024年第4期79卷 651-673页

作者： Ahsan Wajahat Jingsha He Nafei Zhu Tariq Mahmood Tanzila Saba Amjad Rehman Khan faten S.A.lamri Faculty of Information Technology Beijing University of TechnologyBeijing100124China Artificial Intelligence and Data Analytics(AIDA)Lab CCIS Prince Sultan UniversityRiyadh11586Saudi Arabia Faculty of Information Sciences University of EducationVehari CampusVehari61100Pakistan Department of Mathematical Sciences College of SciencePrincess Nourah bint Abdulrahman UniversityRiyadh84428Saudi Arabia

The growing usage of Android smartphones has led to a significant rise in incidents of Android malware andprivacy *** escalating security concern necessitates the development of advanced technologies capableof automatically detecting andmitigatingmalicious activities in Android applications(apps).Such technologies arecrucial for safeguarding user data and maintaining the integrity of mobile devices in an increasingly digital *** methods employed to detect sensitive data leaks in Android apps are hampered by two major limitationsthey require substantial computational resources and are prone to a high frequency of false *** meansthat while attempting to identify security breaches,these methods often consume considerable processing powerand mistakenly flag benign activities as malicious,leading to inefficiencies and reduced reliability in *** proposed approach includes a data preprocessing step that removes duplicate samples,managesunbalanced datasets,corrects inconsistencies,and imputes missing values to ensure data *** Minimaxmethod is then used to normalize numerical data,followed by feature vector extraction using the Gain ratio andChi-squared test to identify and extract the most significant characteristics using an appropriate prediction *** study focuses on extracting a subset of attributes best suited for the task and recommending a predictivemodel based on domain expert *** proposed method is evaluated using Drebin and TUANDROMDdatasets containing 15,036 and 4,464 benign and malicious samples,*** empirical result shows thatthe RandomForest(RF)and Support VectorMachine(SVC)classifiers achieved impressive accuracy rates of 98.9%and 98.8%,respectively,in detecting unknown Androidmalware.A sensitivity analysis experiment was also carriedout on all three ML-based classifiers based on MAE,MSE,R2,and sensitivity parameters,resulting in a flawlessperformance for both *** app

关键词： Android malware detection machine learning SVC K-Nearest Neighbors(KNN) RF

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Carpel Tunnel Syndrome: A Link with Vitamin D, Body Mass Index and Hyperlipidemia

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Neuroscience & Medicine 2024年第1期15卷 55-65页

作者： faten Abdulhady Zakaria Thamer Abdullah Alsufayan Musaad Bedah Alsahly Physiology Department College of Medicine King Saud University AL Riyadh KSA Clinical Physiology Department King Abdul-Aziz University Hospital King Saud University AL Riyadh KSA

Introduction: Carbai tunnel syndrome [CTS] is compression of the median nerve at the wrist , this causes tingling in the hands, pain, numbness, tingling in the fingers particularly the thumb, index and middle fingers, loss of sensation in the hands and fingers, also weakness in the hands. The aim of the present study was to study a possible association which could be found between electrophysiological data in CTS, BMI, hyperlipidemia, and vitamin D [Vit D] levels. Methods: We used a sample of 40 females of the same age group, who were divided into Group 1 as a control consists of 18 healthy females and Group II consisted of 22 age matched females with clinical and electrophysiological evidence of CTS. We measured atherogenic index [AI] as a marker of hyperlipidemia, body mass index [BMI], Vit D status and electrophysiological tests of CTS. Results: Subjects with CTS had deficient Vit D status, they had significantly high atherogenic index (AI), and significant high BMI all compared to control Group I. Median sensory conduction velocity was significantly correlated negatively with BMI and atherogenic index, and positively correlated significantly with Vit D status. But median sensory and motor action potential latency were significantly correlated positively with BMI and atherogenic index, and negatively correlated significantly with Vit D status The analysis revealed BMI, atherogenic index and Vit D status as predictors of median nerve sensory and motor action potential latency and sensory nerve conduction velocity in CTS. Conclusion: The results of this study suggest that obesity and hyperlipidemia are potent CTS risk factors and declared the direct association between Vit D status and CTS occurrence. Our study supports the notion of the compensatory neuroprotective role of Vit D which could have a direct impact on the nerves integrity as it has an anti-inflammatory property which acts in relieving nervous insults and stress. .

关键词： Carpal Tunnel Syndrome Vitamin D Body Mass Index

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Cell surface-expression of the phosphate-binding protein PstS:System development,characterization,and evaluation for phosphorus removal and recovery

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Journal of Environmental Sciences 2020年第6期32卷 129-140页

作者： faten B.Hussein Kaushik Venkiteshwaran Brooke K.Mayer Department of Civil Construction and Environmental EngineeringMarquette UniversityMilwaukeeWI53233USA

Simultaneous overabundance and scarcity of inorganic phosphate(Pi)is a critical issue driving the development of innovative water/wastewater treatment technologies that not only facilitate Pi removal to prevent eutrophication,but also recover Pi for agricultural ***,a cell-surface expressed high-affinity phosphate binding protein(PstS)system was developed,and its Pi capture and release potential was *** was genetically modified to express PstS on its outer membrane using the ice nucleation protein(INP)as an anchoring *** of protein expression and localization were performed utilizing SDS-polyacrylamide gel electrophoresis(SDS-PAGE),western blot,and outer membrane separation *** surface characterization was investigated through acid-base titration,X-ray photoelectron spectroscopy(XPS),and Fourier transform infrared spectroscopy(FTIR).These tests provided information on the macromolecular structure and composition of the bacteria surface as well as the proton-exchange properties of the surface functional groups(i.e.,pKa values).Phosphate desorption and adsorption batch experiments were conducted to evaluate the effects of temperature,pH,and ionic strength on phosphate capture and *** PstS surface-displayed cells demonstrated greater potential to release and capture phosphate compared to non-modified *** temperatures up to 40℃,basic pH conditions(pH=10.5),and higher ionic strength up to 1.0 mol/L KCl promoted 20%-50%higher phosphate release.

关键词： Phosphorus recovery Water treatment Eutrophication Surface-expression PstS protein E.coli bacteria Phosphate

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Population genetic structure of the biological control agent Macrolophus pygmaeus in Mediterranean agroecosystems

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Insect Science 2017年第5期24卷 859-876页

作者： Jean-Claude Streito Cecile Clouett faten Hamdi Nathalie Gauthier IRD UMR (INRA/IRDICiradlMontpellier SupAgro) Centre de Biologie pour la Gestion des Populations INRA UMR (INRA/IRDI CiradlMontpellier SupAgro) Centre de Biologie pour la Gestion des Populations 755 avenue du Campus Agropolis CS 30016 34988Montferrier-sur-Lez France

Biological control of agricultural pests relies on knowledge of agroecosystem functionality, particularly when affected by the use of mass-produced biological agents. Incorporating pre- and/or post-release information such as genetic diversity and struc- ture on these agents using molecular-based approaches could advance our knowledge of how they perform in agroecosystems. We evaluated the population genetics of Macrolo- phus pygmaeus, the most widely used predatory mirid against many arthropod pests of greenhouse crops in the Mediterranean region, using the mitochondrial Cytb sequence and microsatellite data, and population genetics and phylogeny approaches. We investigated commercially mass-produced insects （i.e., commercial insects either mass-reared in the laboratory for many generations, or purchased by farmers and released in the greenhouses） and ＂wild＂ insects （i.e., that occur naturally outside or are collected in nature for release in the greenhouses）. The mirids were mainly collected in agroecosystems in which solana- ceous plants are grown in northern Spain, southern France and Greece. Both molecular markers and approaches distinguished 2 genetically differentiated populations. The less genetically diverse population, hereafter named the ＂commercial＂ strain included all indi- viduals from laboratory mass-rearings and most releases of commercially bred individuals. The most genetically diverse population mainly comprised individuals originating from noncultivated environments, or from releases of＂wild＂ individuals. Rare examples of hy- bridization between M. pygmaeus from the 2 populations were observed and asymmetric gene flow was revealed. These findings provide new insights into what happens to M. pyg- maeus released in the agroecosystems we studied, and show that it is possible to monitor some commercial strains.

关键词： biological control commercial vs. wild strains Macrolophus pygmaeus microsatellites mtCytb population genetics

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On Relations for Moments of Generalized Order Statistics for Lindley–Weibull Distribution

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Computer Systems Science & Engineering 2022年第4期41卷 197-208页

作者： faten A.Momen khan Saman Hanif Shahbaz Muhammad Qaiser Shahbaz Department of Statistics University of JeddahJeddahKingdom of Saudi Arabia Department of Statistics King Abdulaziz UniversityJeddahKingdom of Saudi Arabia

Moments of generalized order statistics appear in several areas of science and *** moments are useful in studying properties of the random variables which are arranged in increasing order of importance,for example,time to failure of a computer *** computation of these moments is sometimes very tedious and hence some algorithms are *** algorithm is to use a recursive method of computation of these moments and is very useful as it provides the basis to compute higher moments of generalized order statistics from the corresponding lower-order *** order statistics pro-vides several models of ordered data as a special *** moments of general-ized order statistics also provide moments of order statistics and record values as a special *** this research,the recurrence relations for single,product,inverse and ratio moments of generalized order statistics will be obtained for Lindley–Weibull *** relations will be helpful for obtained moments of gen-eralized order statistics from Lindley–Weibull distribution *** cases of the recurrence relations will also be *** characterizations of the distribution will also be obtained by using moments of generalized order *** relations for moments and characterizations can be used in differ-ent areas of computer sciences where data is arranged in increasing order.

关键词： Generalized order statistics Lindley–Weibull distribution recurrence relations moments

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Existence and Global Asymptotic Behavior of Positive Solutions for Sublinear and Superlinear Fractional Boundary Value Problems

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Chinese Annals of Mathematics,Series B 2016年第1期37卷 1-28页

作者： Imed BACHAR Habib MAAGLI faten TOUMI Zagharide ZINE EL ABIDINE Mathematics Department College of Science King Saud University P.O.Box 2455 Riyadh 11451 Saudi Arabia. Department of Mathematics College of Sciences and Arts Rabigh Campus King Abdulaz University P.O.Box 344 Rabigh 21911 Saudi Arabia. Departement de Mathematiques Faculte des Sciences de Tunis Campus Universitalre 2092 Tunis Tunisia.

In this paper, the authors aim at proving two existence results of fractional differential boundary value problems of the form （Pa,bα）{D^au（x）＋f（x,u（x））=0,x∈（0,1）,u（0）=u（1）=0,D^a-3u（0）=a,u^（1）=-6where 3 ≤ a 〈 4, D^ is the standard Riemann-Liouville fractional derivative and a, b are nonnegative constants. First the authors suppose that f（x, t） = -p（x）t^σ, with cr ~ （-1, 1） and p being a nonnegative continuous function that may be singular at x - 0 or x - 1 and satisfies some conditions related to the Karamata regular variation theory. Combining sharp estimates on some potential functions and the Sch^uder fixed point theorem, the authors prove the existence of a unique positive continuous solution to problem （P0,0）. Global estimates on such a solution are also obtained. To state the second existence result, the authors assume that a, b are nonnegative constants such that a ＋ b 〉 0 and f（x, t） -= tφ（x, t）, with φ（x, t） being a nonnegative continuous function in （0, 1） × [0, ∞） that is required to satisfy some suitable integrability condition. Using estimates on the Green＇s function and a perturbation argument, the authors prove the existence and uniqueness of a positive continuous solution u to problem （Pa,b）, which behaves like the unique solution of the homogeneous problem corresponding the existence results. to （Pa,b）. Some examples are given to illustrate the existence results.,

关键词： Fractional differential equation Positive solution Fractional Green's function Karamata function Perturbation arguments Sch/iuder fixad point theorem

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Validation of degree-day models for predict!ng the emergence of two fruit flies (Diptera: lephritidae) in northeast Egypt

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Insect Science 2021年第1期28卷 153-164页

作者： Mohamed HBayoumy J.P.Michaud faten AABadr Nabil MGhanim Faculty of Agriculture Economic Entomology DepartmentMansoura UniversityMansouraEgypt Department of Entomology Kansas State UniversityAgricultural Research Center-HaysHaysKansasUSA Agricultural Research Center Plant Protection Research InstituteDokkyGizaEgypt

We estimated thermal developmental thresholds(7o)and degree-day(DD)constants for the immature stages of two tephritid pests,Bcictrocera zonata(Saunders)and Ceratitis capitata(Weidenmann).Males of both species were trapped in an Egyptian guava orchard during the fruiting seasons of 2016 and 2017 and trap catches were compared with peak flights predicted by the DD model based on local weather *** capitata had faster development than *** at 20 and 25°C,but their overall developmental rate was similar at 30 and 35°*** thermal threshold of development(7o)of *** was higher than that of ***,indicating greater sensitivity to *** 35°C yielded the fastest development of both species,survival was higher at 30°C,with *** experiencing a slight advantage,suggesting better tropical *** development of *** and *** was estimated to require 338 and 373 d,respectively,and 616 and 424 DD for a complete *** catches over both seasons showed good correspondence to peaks of fly activity predicted by the DD models;deviations from expectation ranged from 0 to 7 d for both fly *** species had four overlapping generations per season,with *** abundance peaking in the first generation in both years,but only in 2016 for *** models predict about eight and 12 generations per year in northeast Egypt for *** and ***,*** models should be useful for timing pest control measures to coincide with periods of peak fly activity in fruit orchards.

关键词： Bactrocera zonata Ceratitis capitata development forecasting thermal threshold

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Genetic screening for quality-of-life improvement and post-genetic testing consideration in Saudi Arabia

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Family Medicine and Community Health 2018年第2期6卷 70-76页

作者： faten Dhawi Faisal Shehab Alotaibi Biotechnology Department King Faisal UniversityAl HofufAl AhsaSaudi Arabia School of Communication Journalism and MarketingCollege of BusinessMassey UniversityPrivate Bag 11222Palmerston North4442AlbanyNew Zealand

The Saudi genome project started in 2013 with a great hope to improve medical care and disease *** the genes are those related to nutrition and fitness that can optimize an individual’s *** aim was to review the knowledge and acceptance of nutrition and fitness genetic testing to enhance the quality of life among the population of Saudi *** the study an electronic questionnaire consisting of 27 questions was prepared,and it was answered by 302 *** respondents’demographics showed about 50% of respondents were aged 18-25 years and about 50% of respondents were aged 26-60 *** than 50% of respondents were interested in having a genetic test to enhance their health,while 40% were interested in having a genetic test to enhance their *** than 50% of respondents had an understanding of the effects of coffee,macronutrition and micronutrition,elements,and enzyme *** results represented a contribution to the discussion on the relevance of genetic testing validity and acceptance among the population of Saudi *** results might help in producing specific guidelines on genetic testing and genomic analysis and help in the implementation of fitness and future health plans in cooperation with Saudi genome *** study will focus on population structure and genetic frequency related to specific diets or fitness.

关键词： Genetic screening diet fitness nutrition

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