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Determination of the suspension competence of debris flows based on particle size analysis

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International Journal of Sediment Research 2014年第1期29卷 73-81页

作者： Hong-juan YANG fang-qiang wei Kai-heng HU Chuan-chang WANG Key Laboratory of Mountain Hazards and Earth Surface Process Chinese Academy of Sciences Institute of Mountain Hazards and Environment Chinese Academy of Sciences

The determination of the critical particle size between solid and fluid phases,i.e.,the suspension competence,is fundamental for debris flow.A method for determining suspension competence based on particle size analysis is presented in this *** competence of static experimental water-debris mixtures prepared with the sediment of Jiangjia Gully is-0.025 mm if the bulk density is less than 1,800 kg m;and it increases with bulk density of more concentrated *** competence of natural debris flows in Jiangjia Gully increases exponentially with the bulk *** two data sets are compared in order to understand the suspension *** is concluded that turbulence may play a leading role in particle suspension in non-viscous and sub-viscous debris flows,while in viscous debris flows both matrix strength and excess pore water pressure play important roles.

关键词： Debris flow Suspension competence Particle size analysis Critical particle size Particle suspension mechanism

Cystic duct cancer: Should it be deemed as a type of gallbladder cancer?

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World Journal of Gastroenterology 2019年第44期25卷 6541-6550页

作者： Tu-Nan Yu Ying-Ying Mao fang-qiang wei Hui Liu Department of General Surgery Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou 310016Zhejiang ProvinceChina Department of Epidemiology and Biostatistics Zhejiang Chinese Medical UniversityHangzhou 310053Zhejiang ProvinceChina Department of Hepatobiliary and Pancreatic Surgery Zhejiang Provincial People’s HospitalHangzhou Medical CollegeHangzhou 310014Zhejiang ProvinceChina Zhejiang Provincial Key Laboratory of Laparoscopic Technology Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou 310016Zhejiang ProvinceChina

BACKGROUND According to the latest American Joint Committee on Cancer and Union for International Cancer Control manuals,cystic duct cancer(CC)is categorized as a type of gallbladder cancer(GC),which has the worst prognosis among all types of biliary *** hypothesized that this categorization could be verified by using taxonomic *** To investigate the categorization of CC based on population-level *** Cases of biliary cancers were identified from the Surveillance,Epidemiology,and End Results 18 registries *** with routinely used statistical methods,three taxonomic methods,including Fisher’s discriminant,binary logistics and artificial neuron network(ANN)models,were used to clarify the categorizing problem of *** The T staging system of perihilar cholangiocarcinoma[a type of extrahepatic cholangiocarcinoma(EC)]better discriminated CC prognosis than that of *** adjusting other covariates,the hazard ratio of CC tended to be closer to that of EC,although not reaching statistical *** differentiate EC from GC,three taxonomic models were built and all showed good *** ANN model had an area under the receiver operating characteristic curve of *** the three models,the majority(75.0%-77.8%)of CC cases were categorized as *** Our study suggested that CC should be categorized as a type of EC,not *** surgical attitude might be considered in CC cases,to see whether long-term prognosis could be immensely improved like the situation in EC.

关键词： Cystic duct cancer Gallbladder cancer Extrahepatic cholangiocarcinoma Surgical management Taxonomy Categorization

Cloning and Characterization of Porcine TSARG7 Gene and Analysis of Its Tissue-Specific Expression

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Agricultural Sciences in China 2009年第11期8卷 1384-1391页

作者： LI Mei-li LI Gui-qiang fang wei WANG wei SONG Xiao-guang LI Er-lin JIA Chao XU Yin-xue College of Animal Science and Technology Nanjing Agricultural University Nanjing 210095 P.R.China

TSARG7 is a novel member of the acyltransferase family since its sequence possesses the highly conserved phosphate acyltransferase （PlsC） domain existing in all acyltransferase-like proteins. The porcine TSARG7 had been identified by cloning in silico but had not been confirmed experimentally. The full-length mRNA of porcine TSARG7 gene was sequenced and two splice variants were discovered. The full-length cDNA of TSARG7 variant 1 was 2 513 bp and variant 2 was 2 634 bp. The putative porcine TSARG7 proteins, which were located in the cytoplasm, encoded 458 and 456 amino acids, respectively. Real-time PCR analysis showed that TSARG7 gene was expressed in various tissues, but at different levels. The expression levels of this gene were higher in the skeletal muscle, heart, and testis than that in other tissues, suggesting that the TSARG7 gene played a role in procine skeletal muscle, heart, and testis functions.

关键词： TSARG7 cDNA cloning pig bioinformatic analysis gene expression

Is laparoscopic radical cholecystectomy an effective and safe approach for advanced gallbladder cancer?

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Hepatobiliary & Pancreatic Diseases International 2020年第3期19卷 203-204页

作者： Li-Ming Jin Yu-Hua Zhang Cheng-Wu Zhang wei-Ding Wu Jia Wu Chang-wei Dou fang-qiang wei Zhi-Fei Wang Zhi-Ming Hu Shu-Sen Zheng Division of Hepatobiliary Pancreatic Surgery First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Division of Hepatobiliary and Pancreatic Surgery Zhejiang Provincial People’s HospitalAffiliated People’s Hospital of Hangzhou Medical CollegeHangzhou 310014China Department of Hepatobiliary and Pancreatic Surgery Department of Liver TransplantationShulan(Hangzhou)HospitalZhejiang Shuren University School of MedicineHangzhou 310022China

Although laparoscopy has been widely used in the surgical field and is even considered the first-line to diagnose various diseases,laparoscopic radical cholecystectomy(LRC)for gallbladder cancer(GBC)has always been relatively *** lymphadenectomy,complicated liver resection,specific biological behavior of GBC cells,and chimney and aerosol effects from the pneumoperitoneum are the previously misunderstood areas in laparoscopic surgery[1].Initially,laparoscopic approach was used for intra-abdominal GBC exploration to determine the presence of peritoneal metastasis,intraoperative staging,and palliative *** the advancement of laparoscopic surgery,laparoscopic liver resection,laparoscopic pancreaticoduodenectomy,and laparoscopic radical gastrectomy have been routinely performed in several medical *** et al.[2]recently demonstrated that laparoscopic technique is feasible for ***,the feasibility of LRC depends on the following factors.

关键词： laparoscopic gallbladder routine

Can retrohepatic tunnel be quickly and easily established for laparoscopic liver hanging maneuver by Goldfinger dissector in laparoscopic right hepatectomy?

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2016年第9期17卷 712-721页

作者： Liu-xin CAI fang-qiang wei Yi-chen YU Xiu-jun CAI Department of General Surgery Institute of Minimally Invasive SurgerySir Run Run Shaw HospitalSchool of MedicineZhejiang University

Objective： The liver hanging maneuver （LHM） is rarely applied in laparoscopic right hepatectomy （LRH） because of the difficulty encountered in retrohepatic tunnel （RT） dissection and tape positioning. Thus far no report has detailed how to quickly and easily establish RT for laparoscopic LHM in LRH, nor has employment of the Goldfinger dissector to create a total RT been reported. This study＇s aim was to evaluate the safety and feasibility of establishing RT for laparoscopic LHM using the Goldfinger dissector in LRH. Methods： Between March 2015 and July 2015, five consecutive patients underwent LRH via the caudal approach with laparoscopic LHM. A five-step strategy using the Goldfinger dissector to establish RT for laparoscopic LHM was adopted. Perioperative data were analyzed. Results： The median age of patients was 58 （range, 51-65） years. Surgery was performed for one intrahepatic lithiasis and four hepatocellular carcinomas with a median size of 90 （40-150） mm. The median operative time was 320 （282-358） min with a median blood loss of 200 （200-600） ml. Laparoscopic LHM was achieved in a median of 31 （21-62） min, and the median postoperative hospital stay was 14 （9-16） d. No transfusion or conversion was required, and no severe liver-related morbidity or death was observed. Conclusions： The Goldfinger dissector is a useful instrument for the establishment of RT. A five-step strategy using the Goldfinger dissector can quickly and easily facilitate an RT for a laparoscopic LHM in LRH.

关键词： Retrohepatic tunnel Liver hanging maneuver Goldfinger dissector Laparoscopic right hepatectomy

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组合式视频点播系统在医学教学中的应用

现代教育技术 2009年第9期19卷 140-142页

作者：赵强房维强徐州医学院现代教育技术中心江苏徐州221004

视频教学法在医学形态学科的教学应用中越来越突出,但其应用的形式由于受到技术手段的限制而显得比较单调和繁琐,创建一种简单而高效的应用平台,对于普及视频教学手段显得尤为重要。文章通过笔者利用SMIL语言而创建的平台来向大家展示... 详细信息

视频教学法在医学形态学科的教学应用中越来越突出,但其应用的形式由于受到技术手段的限制而显得比较单调和繁琐,创建一种简单而高效的应用平台,对于普及视频教学手段显得尤为重要。文章通过笔者利用SMIL语言而创建的平台来向大家展示一种新的教学思路。

关键词：视频教学视频片段组合 SMIL

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基于流媒体技术的三分屏课件制作

现代教育技术 2009年第5期19卷 136-138页

作者：刘梓红房维强徐州工程学院教育科学与技术学院江苏徐州221009 徐州医学院现代教育技术中心江苏徐州221004

文章主要讨论了目前一种比较热门的网络课件形式——三分屏课件的特点、优势及其相关的制作工具,并对其制作过程进行简单的介绍,帮助广大老师快速了解掌握三分屏课件的制作,促进三分屏课件在教学中的应用。

关键词：三分屏 stramauthor 布局模板编辑课件录制与编辑

非糖尿病危重症患者的血糖波动对病死率的影响

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中国急救医学 2014年第1期34卷 79-82页

作者：彭绵方伟强蔡举瑜香港大学深圳医院ICU 广东深圳518053 汕头大学医学院第一附属医院ICU

目的探讨非糖尿病危重症患者的血糖波动对病死率的影响。方法采用前瞻、随机的临床研究方法，以239例非糖尿病危重症患者为研究对象，以血糖标准差评估血糖波动程度，根据血糖标准差将所有患者分为两组：高波动组（血糖标准差≥血糖平... 详细信息

目的探讨非糖尿病危重症患者的血糖波动对病死率的影响。方法采用前瞻、随机的临床研究方法，以239例非糖尿病危重症患者为研究对象，以血糖标准差评估血糖波动程度，根据血糖标准差将所有患者分为两组：高波动组（血糖标准差≥血糖平均值）与低波动组（血糖标准差〈血糖平均值），统计所有患者的病死率，分析血糖波动对病死率的影响。结果在排除肠内营养及激素用量影响的前提下，血糖波动性较小的危重症患者病死率明显降低（4．O％vs13．0％，P〈0．05），存活患者的ICU住院时间明显缩短[（5．9±2．0）dV8（15．2±7．7）d，P〈0．05]。与血糖波动性相比，不同的绝对血糖值对危重症患者病死率（6．2％V87．3％，P〉0．05）及ICU住院时间[（9．3±3．0）dVS（11．3±5．9）d，P〉0．05]的影响差异均无统计学意义。结论血糖波动性低的危重症患者病死率较低。

关键词：危重症血糖波动病死率

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微小型质子交换膜燃料电池性能测试分析

电源技术 2013年第1期37卷 16-18,126页

作者：梁灵威方伟强万珍平苏凌峰浙江大学机械工程系浙江杭州310027 华南理工大学机械与汽车工程学院广东广州510640

微小型质子交换膜燃料电池(mPEMFC)在便携式电子设备、便携式军用设备等领域有着广泛的应用前景。搭建了微小型燃料电池性能测试平台,对三种极板流场的微小型PEMFC性能进行比较,并研究了不同的运行参数对交指流场微小型PEMFC性能的影响... 详细信息

微小型质子交换膜燃料电池(mPEMFC)在便携式电子设备、便携式军用设备等领域有着广泛的应用前景。搭建了微小型燃料电池性能测试平台,对三种极板流场的微小型PEMFC性能进行比较,并研究了不同的运行参数对交指流场微小型PEMFC性能的影响。实验结果表明,交指流场的微小型PEMFC性能最佳,蛇形流场次之,平行流场最差,交指流场的微小型PEMFC的性能受其电池温度和加湿温度影响较大,性能随气压升高而稍有提高。实验结果对提高微小型PEMFC的性能有一定参考价值,有利于微小型PEMFC在生活中的推广应用。

关键词：微小型燃料电池质子交换膜燃料电池交指流场