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越鞠保和丸联合穴位埋线对肝胃不和型功能性消化不良患者胃动力指标、血清胃肠激素和胃蛋白酶原的影响

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现代生物医学进展 2024年第6期24卷 1109-1113页

作者：赵文麟黄洪伟范逸品李婧李琰琴吴慧青赵文树首都医科大学附属鼓楼中医医院(北京市鼓楼中医医院)治未病科北京100009 首都医科大学附属鼓楼中医医院(北京市鼓楼中医医院)中医科北京100009 中国中医科学院中医临床基础医学研究所北京100700 首都医科大学附属鼓楼中医医院(北京市鼓楼中医医院)针灸科北京100009 首都医科大学附属鼓楼中医医院(北京市鼓楼中医医院)检验科北京100009 上海中医药大学附属龙华医院中医科上海200032

目的:探讨越鞠保和丸联合穴位埋线对肝胃不和型功能性消化不良(FD)患者胃动力指标、血清胃肠激素和胃蛋白酶原的影响。方法:采用随机数字表法将2020年6月~2023年6月期间北京市鼓楼中医医院收治的123例FD患者分为对照组(61例)和研究组(62... 详细信息

目的:探讨越鞠保和丸联合穴位埋线对肝胃不和型功能性消化不良(FD)患者胃动力指标、血清胃肠激素和胃蛋白酶原的影响。方法:采用随机数字表法将2020年6月~2023年6月期间北京市鼓楼中医医院收治的123例FD患者分为对照组(61例)和研究组(62例)。对照组接受常规治疗联合穴位埋线治疗,研究组在对照组的基础上结合越鞠保和丸治疗。对比两组疗效、中医证候积分、胃动力指标、胃肠激素指标和胃蛋白酶原指标。结果:研究组的临床总有效率高于对照组(P<0.05)。治疗后研究组主症、次症、中医证候积分总分低于对照组(P<0.05)。治疗后研究组胃动素(MLT)高于对照组,生长抑素(SS)、胃泌素(GAS)低于对照组(P<0.05)。治疗后研究组餐后胃窦收缩频率(F)、收缩幅度(P)、运动指数(MI)高于对照组(P<0.05)。治疗后研究组胃蛋白酶原Ⅰ(PGⅠ)、胃蛋白酶原Ⅱ(PGⅡ)高于对照组(P<0.05)。结论:越鞠保和丸联合穴位埋线可有效改善肝胃不和型FD患者的血清胃肠激素和胃蛋白酶原水平,促进胃动力,进而改善胃肠功能。

关键词：越鞠保和丸穴位埋线肝胃不和功能性消化不良胃动力胃肠激素胃蛋白酶原

Recent Progress on Water-based Liquid Embolic Agents in Endovascular Treatment

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Chemical Research in Chinese Universities 2024年第5期40卷 776-785页

作者： QI yi fan Hailong Department of Neurosurgery Faculty of Medicine and Graduate School of MedicineHokkaido UniversitySapporo060-8638Japan Institute for Chemical Reaction Design and Discovery(WPI-ICReDD) Hokkaido UniversitySapporo001-0021Japan

Vascular embolization treatment,a minimally invasive surgery for various blood vessel-related conditions,has emerged as a crucial method in treating such as hemorrhage,arteriovenous malformation,aneurysms,and hypervascular *** embolic agents are gaining prominence due to their distinct advantage in infiltrating distal regions,expanding the scope of embolization beyond the reach of solid *** strides in biomaterials and technologies have spurred the development of novel liquid embolic agents,addressing challenges posed by traditional *** mini-review provides a concise overview of the recent progress in water-based liquid embolic agents,highlighting their potential to overcome limitations associated with current embolic *** presenting selected research outcomes,we illuminate advancements that enhance the efficacy of liquid embolic ***,the review outlines essential properties for effective liquid embolic agents,offering insights for future developments in this field.

关键词： Endovascular treatment Lquid embolic agent Hydrogel

In memory of Robie ***(1948-2022):A scientist and a friend

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Environmental Science and Ecotechnology 2024年第2期18卷 4-6页

作者： yi-fan Li 不详

On February 17,2022,I received an email from Julie Henderson,the life partner of Robie *** her email,she conveyed the following message:"Hello yifan,Rob asked me to especially let you know that when he had *** admired and enjoyed working with you."As I read those words,tears welled up in my eyes,overwhelmed by profound *** was not only my scientific research colleague but also my closest *** had collaborated for more than two decades.

关键词： email friend partner

A Case Series of Olfactory Dysfunction in Imported COVID-19 Patients:A 12-Month Follow-Up Study

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Biomedical and Environmental Sciences 2022年第5期35卷 402-411页

作者： WANG Ni YANG Ming Bo YANG Pu Ye CHEN Ren Bo HUANG Fei SHI Nan Nan MA Yan ZHANG Yan XU You LIU Si Hong LU Heng yi FU Qing Qing fan yi pin KAN Hong Min WANG Xiao Hong GUO Ya Ling National Center for Tuberculosis Control and Prevention Chinese Center for Disease Control and PreventionBeijing 102206China Hepatology Department of TCM Xi’an NO.8 HospitalXi’an 710061ShaanxiChina Department of Integrated Chinese and Western Medicine Xi’an NO.8 HospitalXi’an 710061ShaanxiChina Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijing 100700China Department of Infection Xi’an NO.8 HospitalXi’an 710061ShaanxiChina Institute of Information on Traditional Chinese Medicine China Academy of Chinese Medical SciencesBeijing 100700China

Objective The scientific community knows little about the long-term influence of coronavirus disease2019(COVID-19) on olfactory dysfunction(OD). With the COVID-19 pandemic ongoing worldwide, the risk of imported cases remains high. In China, it is necessary to understand OD in imported *** A prospective follow-up design was adopted. A total of 11 self-reported patients with COVID-19 and OD from Xi’an No. 8 Hospital were followed between August 19, 2021, and December 12, ***, clinical characteristics, laboratory and radiological findings, and treatment outcomes were analyzed at admission. We surveyed the patients via telephone for recurrence and sequelae at the1-, 6-, and 12-month *** Eleven patients with OD were enrolled;of these, 54.5%(6/11) had hyposmia and 45.5%(5/11)had anosmia. 63.6%(7/11) reported OD before or on the day of admission as their initial symptom;of these, 42.9%(3/7) described OD as the only symptom. All patients in the study received combined treatment with traditional Chinese medicine and Western medicine, and 72.7%(8/11) had partially or fully recovered at discharge. In terms of OD recovery at the 12-month follow-up, 45.5%(5/11) reported at least one sequela, 81.8%(9/11) had recovered completely, 18.2%(2/11) had recovered partially, and there were no recurrent *** Our data revealed that OD frequently presented as the initial or even the only symptom among imported cases. Most OD improvements occurred in the first 2 weeks after onset, and patients with COVID-19 and OD had favorable treatment outcomes during long-term follow-up. A better understanding of the pathogenesis and appropriate treatment of OD is needed to guide clinicians in the care of these patients.

关键词： COVID-19 Olfactory Imported cases Hyposmia Anosmia Follow-up

Qingfei Paidu Decoction for COVID-19: A Bibliometric Analysis

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Biomedical and Environmental Sciences 2021年第9期34卷 755-760页

作者： LIU Si Hong MA Yan SHI Nan Nan TONG Lin ZHANG Lei CHEN Ren Bo fan yi pin JI Xin Yu GE You Wen ZHANG Hua Min WANG Yan ping WANG Yong Yan Institute of Information on Traditional Chinese Medicine China Academy of Chinese Medical SciencesBeijing 100700China Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijing 100700China Institute of Chinese Materia Medica China Academy of Chinese Medical SciencesBeijing 100700China

Traditional Chinese medicine(TCM)has been used for thousands of years in fighting epidemics and has achieved remarkable therapeutic effects[1].The coronavirus disease 2019(COVID-19)pandemic has been effectively contro... 详细信息

关键词： medicine(TCM) Decoction Qing

Disposal of zinc extraction residues via iron ore sintering process:an innovative resource utilization

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Journal of Iron and Steel Research International 2024年第7期31卷 1636-1645页

作者： Chun-long fan Cheng-yi Ding Tao Yang Yun-fei Luo yi-fan Wang Qian Li Hong-ming Long School of Metallurgical Engineering Anhui University of TechnologyMa'anshan 243002AnhuiChina Zhongye Changtian International Engineering Co. Ltd.Changsha 410205HunanChina Key Laboratory of Metallurgical Emission Reduction and Resources Recycling(Ministry of Education) Anhui University of TechnologyMa'anshan 243002AnhuiChina

Zinc extraction residue,a solid waste generated from the treatment of zinc-containing dust in rotary kilns,is commonly stockpiled in steel companies for extended *** poses significant disposal challenges and environmental pollution *** far,research on the treatment of zinc extraction residues has been slow,inadequate,and *** this gap,a novel approach was proposed to effectively treat the zinc extraction residue via the iron ore sintering *** was feasible to add 1 wt.%of zinc extraction residues to the sintering raw *** more adequate mineralization reaction resulted in higher yield and tumbler indexes,despite a slight decrease in sintering *** this may result in a slight decrease in sintering speed,the more complete mineralization reaction leads to improved sintering yield and tumbler ***,the addition of zinc extraction residues reduced the CO and NO_(x) concentrations in the sintering flue ***,the iron ore sintering process provided a viable solution for resource utilization and environmentally friendly treatment of zinc extraction residues.

关键词： Zinc extraction residue Iron ore sintering Co-processing Waste utilization Gas pollutant reduction

Silicon dioxide-protection boosting the peroxidase-like activity of Fe single-atom catalyst for combining chemo-photothermal therapy

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Nano Research 2024年第6期17卷 4924-4933页

作者： Yu fan Yu yi Hongpan Rong Jiatao Zhang Beijing Key Laboratory of Construction-Tailorable Advanced Functional Materials and Green Applications School of Materials Science&EngineeringBeijing Institute of TechnologyBeijing 100081China CAS Center for Excellence in Nanoscience CAS KeyLaboratory for Biomedical Effects of Nanomaterials and NanosafetyNational Center for Nanoscience and Technology(NCNST)Beijing 100190China Key Laboratory of Medical Molecule Science and Pharmaceutics Engineering Ministry of Industry and Information TechnologySchool of Chemistry&Chemical EngineeringBeijing Key Laboratory of Construction-Tailorable Advanced Functional Materials and Green ApplicationsSchool of Materials Science and EngineeringBeijing Institute of TechnologyBeijing 100081China

Carbon-based single-atom catalysts(SACs)have been widely studied in the field of biomedicine due to their excellent catalytic ***,carbon-based SACs usually aggregate during pyrolysis,which leads to the reduction of catalytic ***,we describe a method to improve the monodispersion of SACs using silicon dioxide as a protective *** decoration of silicon dioxide serves as a buffer layer for individual nanoparticles,which is not destroyed during the pyrolysis process,ensuring the single-particle dispersion of the nanoparticles after *** approach increased the hydroxyl groups on the surface of Fe-SAC(Fe-SAC-SE)and improved its water solubility,resulting in a four times enhancement of the peroxidase(POD)-like activity of Fe-SAC-SE(58.4 U/mg)than that of non-protected SACs(13.9 U/mg).The SiO_(2)-protection approach could also improve the catalytic activities of SACs with other metals such as Mn,Co,Ni,and Cu,indicating its generality for SACs *** advantage of the high POD-like activity,photothermal properties,and large specific surface area of Fe-SAC-SE,we constructed a synergistic therapeutic system(Fe-SAC-SE@DOX@PEG)for combining the photothermal therapy,catalytic therapy,and *** was verified that the photothermal properties of Fe-SAC-SE@DOX@PEG could effectively improve its POD-like activity,exhibiting excellent tumor-killing performance at the cellular *** work may provide a general approach to improve the performances of SACs for disease therapy and diagnosis.

关键词： single-atom catalysts peroxidase-like activity SiO2-protection photothermal therapy catalytic therapy chemotherapy

Mitigating methane emissions:Domestic and joint efforts by the United States and China

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Environmental Science and Ecotechnology 2024年第4期20卷 2-5页

作者： fan Dai yi Wang California-China Climate Institute The University of CaliforniaBerkeleyUSA Institutes of Science and Development Chinese Academy of SciencesBeijingChina University of Chinese Academy of Sciences BeijingChina

During the Glasgow climate conference,the United States(U.S.)and China jointly committed to reduce methane emissions as a prioritized area of their bilateral cooperation in addressing climate change in the *** methane's strongwarming effect,which is over 80 times more potent than carbon dioxide in the first 20 years after release,reducing methane emissions is crucial to slowing down climate change in the near future[1].1 The significance of this joint commitment was reiterated in the recent U.S.-China Sunnylands Statement on Climate Cooperation,emphasizing the urgency and importance of reducing methane emissions both within each country's borders and through collaborative efforts.

关键词： methane dioxide iterated

Epileptic brain network mechanisms and neuroimaging techniques for the brain network

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Neural Regeneration Research 2024年第12期19卷 2637-2648页

作者： yi Guo Zhonghua Lin Zhen fan Xin Tian Department of Neurology Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina Sichuan Provincial Center for Mental Health Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina Department of Geriatrics Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina Department of Neurology Chongqing Key Laboratory of NeurologyThe First Affiliated Hospital of Chongqing Medical UniversityChongqingChina

Epilepsy can be defined as a dysfunction of the brain network,and each type of epilepsy involves different brain-network changes that are implicated diffe rently in the control and propagation of interictal or ictal *** more detailed information on brain network alterations can help us to further understand the mechanisms of epilepsy and pave the way for brain network-based precise therapeutic approaches in clinical *** increasing number of advanced neuroimaging techniques and electrophysiological techniques such as diffusion tensor imaging-based fiber tra ctography,diffusion kurtosis imaging-based fiber tractography,fiber ball imagingbased tra ctography,electroencephalography,functional magnetic resonance imaging,magnetoencephalography,positron emission tomography,molecular imaging,and functional ultrasound imaging have been extensively used to delineate epileptic *** this review,we summarize the relevant neuroimaging and neuroelectrophysiological techniques for assessing structural and functional brain networks in patients with epilepsy,and extensively analyze the imaging mechanisms,advantages,limitations,and clinical application ranges of each technique.A greater focus on emerging advanced technologies,new data analysis software,a combination of multiple techniques,and the construction of personalized virtual epilepsy models can provide a theoretical basis to better understand the brain network mechanisms of epilepsy and make surgical decisions.

关键词： electrophysiological techniques epilepsy functional brain network functional magnetic resonance imaging functional near-infrared spectroscopy machine leaning molecular imaging neuroimaging techniques structural brain network virtual epileptic models