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Acquiring Weak Annotations for Tumor Localization in Temporal and Volumetric Data

Machine Intelligence Research 2024年第2期21卷 318-330页

作者： Yu-Cheng Chou Bowen Li Deng-ping fan Alan Yuille Zongwei Zhou Department of Computer Science Johns Hopkins UniversityBaltimore 21218USA Computer Vision Lab ETH ZurichZurich 8001Switzerland

Creating large-scale and well-annotated datasets to train AI algorithms is crucial for automated tumor detection and ***,with limited resources,it is challenging to determine the best type of annotations when annotating massive amounts of unlabeled *** address this issue,we focus on polyps in colonoscopy videos and pancreatic tumors in abdominal CT scans;Both applications require significant effort and time for pixel-wise annotation due to the high dimensional nature of the data,involving either temporary or spatial *** this paper,we develop a new annotation strategy,termed Drag&Drop,which simplifies the annotation process to drag and *** annotation strategy is more efficient,particularly for temporal and volumetric imaging,than other types of weak annotations,such as per-pixel,bounding boxes,scribbles,ellipses and ***,to exploit our Drag&Drop annotations,we develop a novel weakly supervised learning method based on the watershed *** results show that our method achieves better detection and localization performance than alternative weak annotations and,more importantly,achieves similar performance to that trained on detailed per-pixel ***,we find that,with limited resources,allocating weak annotations from a diverse patient population can foster models more robust to unseen images than allocating per-pixel annotations for a small set of *** summary,this research proposes an efficient annotation strategy for tumor detection and localization that is less accurate than per-pixel annotations but useful for creating large-scale datasets for screening tumors in various medical modalities.

关键词： Weak annotation detection localization segmentation colonoscopy abdomen

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Editorial for Special Issue on Multi-modal Representation Learning

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Machine Intelligence Research 2024年第4期21卷 615-616页

作者： Deng-ping fan Nick Barnes Ming-Ming Cheng Luc Van Gool Nankai University China&ETH ZürichSwitzerland Australian National University Australia Nankai University China ETH Zürich Switzerland

The past decade has witnessed the impressive and steady development of single-modal AI technologies in several fields,thanks to the emergence of deep *** studied,however,is multi-modal AI-commonly considered the next generation of AI-which utilizes complementary context concealed in different-modality inputs to improve *** naturally learn to form a global concept from multiple modalities(i.e.,sight,hearing,touch,smell,and taste),even when some are incomplete or ***,in addition to the two popular modalities(vision and language),other types of data such as depth,infrared information,and events are also important for multi-modal learning in real-world scenes.

关键词： modal utilize incomplete

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Interface optimization and defects suppression via Na F introduction enable efficient flexible Sb_(2)Se_(3) thin-film solar cells

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Journal of Energy Chemistry 2024年第3期90卷 165-175,I0006页

作者： Mingdong Chen Muhammad Ishaq Donglou Ren Hongli Ma Zhenghua Su ping fan David Le Coq Xianghua Zhang Guangxing Liang Shuo Chen Shenzhen Key Laboratory of Advanced Thin Films and Applications Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong ProvinceCollege of Physics and Optoelectronic EngineeringShenzhen UniversityShenzhen 518060GuangdongChina State Key Laboratory of Featured Metal Materials and Life-cycle Safety for Composite Structures MOE Key Laboratory of New Processing Technology for Nonferrous Metals and MaterialsSchool of ResourcesEnvironment and MaterialsGuangxi UniversityNanning 530004GuangxiChina CNRS ISCR(Institut des Sciences Chimiques de Rennes)UMR 6226Universitéde RennesRennes F-35000France

Sb_(2)Se_(3) with unique one-dimensional(1D) crystal structure exhibits exceptional deformation tolerance,demonstrating great application potential in flexible ***,the power conversion efficiency(PCE) of flexible Sb_(2)Se_(3) photovoltaic devices is temporarily limited by the complicated intrinsic defects and the undesirable contact ***,a high-quality Sb_(2)Se_(3) absorber layer with large crystal grains and benign [hkl] growth orientation can be first prepared on a Mo foil *** NaF intermediate layer is introduced between Mo and Sb_(2)Se_(3),which can further optimize the growth of Sb_(2)Se_(3)thin ***,positive Na ion diffusion enables it to dramatically lower barrier height at the back contact interface and passivate harmful defects at both bulk and *** a result,the champion substrate structured Mo-foil/Mo/NaF/Sb_(2)Se_(3)/CdS/ITO/Ag flexible thin-film solar cell delivers an obviously higher efficiency of 8.03% and a record open-circuit voltage(V_(OC)) of 0.492 *** flexible Sb_(2)Se_(3) device also exhibits excellent stability and flexibility to stand large bending radius and multiple bending times,as well as superior weak light photo-response with derived efficiency of 12.60%.This work presents an effective strategy to enhance the flexible Sb_(2)Se_(3) device performance and expand its potential photovoltaic applications.

关键词： Sb_(2)Se_(3) Flexible solar cells NaF intermediate layer Interface optimization Defects suppression

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Efficacy of Raw Corn Starch in Insulinoma-Related Hypoglycemia:A Promising Supportive Therapy

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Chinese Medical Sciences Journal 2024年第2期39卷 102-110页

作者： Rong-Rong Li Wei Chen Xin-Hua Xiao Miao Yu fan ping Lian Duan Department of Clinical Nutrition Beijing Key Laboratory of the Innovative Development of Functional Staple and the Nutritional Intervention for Chronic DiseaseChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China Department of Endocrinology Peking Union Medical College HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China

Objective To investigate the efficacy of raw corn starch(RCS)in clinical management of insulinoma-induced *** We retrospectively collected clinical data of insulinoma patients who received RCS-supplemented diet preoperatively,and analyzed the therapeutic effects of the RCS intervention on blood glucose control,weight change,and its adverse *** The study population consisted of 24 cases of insulinoma patients,7 males and 17 females,aged 46.08±14.15 *** RCS-supplemented diet,all patients had frequent hypoglycemic episodes(2.51±3.88 times/week),concurrent with neuroglycopenia(in 83.3% of patients)and autonomic manifestations(in 75.0% of patients),with the median fasting blood glucose(FBG)of 2.70(interquartile range[IQR]:2.50-2.90)mmol/*** patients'weight increased by 0.38(IQR:0.05-0.65)kg per month,with 8(33.3%)cases developing overweight and 7(29.2%)cases developing *** patients maintained the RCS-supplemented diet until they underwent tumor resection(23 cases)and transarterial chemoembolization for liver metastases(1 case).For 19 patients receiving RCS throughout the day,the median FBG within one week of nutritional management was 4.30(IQR:3.30-5.70)mmol/L,which was a significant increase compared to pre-nutritional level[2.25(IQR:1.60-2.90)mmol/L;P<0.001].Of them,10 patients receiving RCS throughout the day for over four weeks had sustained improvement in FBG compared to pre-treatment[3.20(IQR:2.60-3.95)mmol/L vs.2.15(IQR:1.83-2.33)mmol/L;P<0.001].Five patients who received RCS only at night also had a significant increase in FBG within one week of nutritional management[3.50(IQR:2.50-3.65)mmol/L vs.2.20(IQR:1.80-2.60)mmol/L;P<0.001],but only one patient who continued to receive RCS for over four weeks did not have a significant improvement in *** improvement in weight gain was observed upon RCS *** diarrhea(2 cases)and flatulence(1 case)occurred,and were relieved by reduction of RCS ***

关键词： corn starch hypoglycemia insulinoma nutrition therapy

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Ultrahigh thermoelectric properties of p-type BixSb2-xTe3 thin films with exceptional flexibility for wearable energy harvesting

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CARBON ENERGY 2024年第8期6卷 273-284页

作者： Zheng, Zhuang-Hao Zhong, Yi-Ming Li, Yi-Liu Nisar, Mohammad Mansoor, Adil Li, Fu Chen, Shuo Liang, Guang-Xing fan, ping Xu, Dongyan Wei, Meng Chen, Yue-Xing Shenzhen Univ Coll Phys & Optoelect Engn Shenzhen Key Lab Adv Thin Films & Applicat Key Lab Optoelect Devices & Syst Minist Educ & Gua Shenzhen Peoples R China Shenzhen Univ Coll Phys & Optoelect Engn Shenzhen Key Lab Adv Thin Films & Applicat Key Lab Optoelect Devices & Syst Minist Educ & Gua Shenzhen 518060 Peoples R China Chinese Univ Hong Kong Dept Mech & Automat Engn Sha Tin Hong Kong Peoples R China

Use of a flexible thermoelectric source is a feasible approach to realizing self-powered wearable electronics and the Internet of Things. Inorganic thin films are promising candidates for fabricating flexible power supply, but obtaining high-thermoelectric-performance thin films remains a big challenge. In the present work, a p-type BixSb2-xTe3 thin film is designed with a high figure of merit of 1.11 at 393 K and exceptional flexibility (less than 5% increase in resistance after 1000 cycles of bending at a radius of similar to 5 mm). The favorable comprehensive performance of the BixSb2-xTe3 flexible thin film is due to its excellent crystallinity, optimized carrier concentration, and low elastic modulus, which have been verified by experiments and theoretical calculations. Further, a flexible device is fabricated using the prepared p-type BixSb2-xTe3 and n-type Ag2Se thin films. Consequently, an outstanding power density of similar to 1028 mu W cm(-2) is achieved at a temperature difference of 25 K. This work extends a novel concept to the fabrication of high-performance flexible thin films and devices for wearable energy harvesting.

关键词： BixSb2-xTe3 electrical transport properties flexibility thermoelectric THERMAL-CONDUCTIVITY BI2TE3 FILMS PERFORMANCE SB2TE3 FIGURE MERIT ENHANCEMENT FABRICATION TRANSITION COMPOSITE

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基于位平面分解的量子彩色图像加密方案

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北京工业大学学报 2024年第7期50卷 832-844页

作者：范萍沈政华东交通大学信息工程学院南昌330013 闽江学院计算机与控制工程学院福州350108

一般的量子图像加密算法虽然能达到加密效果,但需要的量子比特数较多,计算复杂度较高,为优化这一问题,提出了一种位平面分解的量子彩色图像加密方案。首先,采用一种位平面序信息单独编码的彩色数字图像量子表示模型(quantum representat... 详细信息

一般的量子图像加密算法虽然能达到加密效果,但需要的量子比特数较多,计算复杂度较高,为优化这一问题,提出了一种位平面分解的量子彩色图像加密方案。首先,采用一种位平面序信息单独编码的彩色数字图像量子表示模型(quantum representation model of color digital image,QRCI)来表示图像,利用量子交换门设计一种量子位交换操作,并作用于彩色图像中,对图像像素进行置乱,同时再对图像进行颜色通道交换操作。其次,对位平面序列进行反序操作,进一步加强置乱效果。接着,利用安全散列算法(secure hash algorithm 256,SHA-256)产生的哈希值来确定混沌系统的初始值。最后,利用混沌系统产生的序列对图像进行扩散,完成加密过程,形成加密图像。数值分析表明,相较于以往的加密方案,此方案大大降低了彩色图像存储时所需的量子比特位数,同时其密钥空间大,灵敏度高。仿真结果表明,该方案加密效果好,能抵御大部分常见的攻击。

关键词：位平面图像加密量子位交换通道交换 SHA-256 超混沌系统

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基于改进高斯混合粒子滤波新算法的桥梁极值应力动态预测

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吉林大学学报（工学版） 2024年第4期54卷 1038-1044页

作者：樊学平刘月飞兰州大学西部灾害与环境力学教育部重点实验室兰州730000 兰州大学土木工程与力学学院兰州730000

将极值应力数据视为时间序列,提出了桥梁结构极值应力的改进高斯混合粒子滤波(IGMPF)动态预测新方法。首先,利用桥梁健康监测极值应力数据建立动态非线性模型,将其作为粒子滤波算法的状态方程和监测方程;然后,引入最大期望(EM)算法来估... 详细信息

将极值应力数据视为时间序列,提出了桥梁结构极值应力的改进高斯混合粒子滤波(IGMPF)动态预测新方法。首先,利用桥梁健康监测极值应力数据建立动态非线性模型,将其作为粒子滤波算法的状态方程和监测方程;然后,引入最大期望(EM)算法来估计目标状态的概率分布,并嵌入高斯混合粒子滤波器中,进而利用改进高斯混合粒子滤波算法,结合应力监测数据实现结构极值应力的动态预测;最后,通过在役桥梁监测数据对本文模型和方法的合理性进行验证。结果表明:本文方法预测精度高,可用于工程实际应用中。

关键词：结构工程极值应力动态非线性模型最大期望算法高斯混合粒子滤波器

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Triceps skinfold thickness trajectories and the risk of all-cause mortality:A prospective cohort study

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World Journal of Clinical Cases 2024年第15期12卷 2568-2577页

作者： Na Yang Li-Yun He Zi-Yi Li Yu-Cheng Yang fan ping Ling-Ling Xu Wei Li Hua-Bing Zhang Yu-Xiu Li Department of Endocrinology Key Laboratory of Endocrinology of National Health CommissionPeking Union Medical College HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China

BACKGROUND The measurement of triceps skinfold(TSF)thickness serves as a noninvasive metric for evaluating subcutaneous fat *** its clinical utility,the TSF thickness trajectories and their correlation with overall mortality have not been thoroughly *** To explore TSF thickness trajectories of Chinese adults and to examine their associations with all-cause *** This study encompassed a cohort of 14747 adults sourced from the China Health and Nutrition *** class trajectory modeling was employed to identify distinct trajectories of TSF *** were classified into subgroups reflective of their respective TSF thickness *** utilized multivariate Cox regression analyses and mediation examinations to explore the link between TSF thickness trajectory and overall mortality,including contributory *** Upon adjustment for multiple confounding factors,we discerned that males in the‘Class 2:Thin-stable’and‘Class 3:Thin-moderate’TSF thickness trajectories exhibited a markedly reduced risk of mortality from all causes in comparison to the‘Class 1:Extremely thin’*** the mediation analyses,the Geriatric Nutritional Risk Index was found to be a partial intermediary in the relationship between TSF thickness trajectories and *** females,a lower TSF thickness pattern was significantly predictive of elevated all-cause mortality risk exclusively within the non-elderly *** In males and non-elderly females,lower TSF thickness trajectories are significantly predictive of heightened mortality risk,independent of single-point TSF thickness,body mass index,and waist circumference.

关键词： Triceps skinfold thickness Trajectory All-cause mortality Body mass index Geriatric Nutritional Risk Index

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Dipeptidyl peptidase-4 inhibitors and the risk of infection: A systematic review and meta-analysis of cardiovascular outcome trials

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World Journal of Diabetes 2024年第5期15卷 1011-1020页

作者： Na Yang Li-Yun He Peng Liu Zi-Yi Li Yu-Cheng Yang fan ping Ling-Ling Xu Wei Li Hua-Bing Zhang Yu-Xiu Li Department of Endocrinology Key Laboratory of Endocrinology of National Health CommissionPeking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Department of Endocrinology The First Affiliated Hospitaland College of Clinical Medicine of Henan University of Science and TechnologyLuoyang 471000Henan ProvinceChina

BACKGROUND Since adverse events during treatment affect adherence and subsequent glycemic control,understanding the safety profile of oral anti-diabetic drugs is imperative for type 2 diabetes mellitus(T2DM)*** To evaluate the risk of infection in patients with T2DM treated with dipeptidyl-peptidase 4(DPP-4)*** Electronic databases were *** selection criteria included randomized controlled trials focused on cardiovascular *** these studies,the effects of DPP-4 inhibitors were directly compared to those of either other active anti-diabetic treatments or *** trials involving 53616 patients were deemed *** calculated aggregate relative risks employing both random-effects and fixed-effects approaches,contingent upon the *** The application of DPP-4 inhibitors showed no significant link to the overall infection risk[0.98(0.95,1.02)]or the risk of serious infections[0.96(0.85,1.08)],additionally,no significant associations were found with opportunistic infections[0.69(0.46,1.04)],site-specific infections[respiratory infection 0.99(0.96,1.03),urinary tract infections 1.02(0.95,1.10),abdominal and gastrointestinal infections 1.02(0.83,1.25),skin structure and soft tissue infections 0.81(0.60,1.09),bone infections 0.96(0.68,1.36),and bloodstream infections 0.97(0.80,1.18)].CONCLUSION This meta-analysis of data from cardiovascular outcome trials revealed no heightened infection risk in patients undergoing DPP-4 inhibitor therapy compared to control cohorts.

关键词： T2DM drugs treatment

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不平衡电网电压下MMC-UPQC的无源超螺旋二阶滑模控制策略

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控制与决策 2024年第5期39卷 1487-1497页

作者：黄祖繁周建萍茅大钧齐国庆从帆平上海电力大学自动化工程学院上海200090

基于模块化多电平换流器(modular multilevel converter, MMC)的统一电能质量调节器(unified power quality conditioner, UPQC)在电网电压不平衡时,采用传统控制方法存在补偿效率和精确性较低的问题.针对这一情况,提出一种无源超螺旋... 详细信息

基于模块化多电平换流器(modular multilevel converter, MMC)的统一电能质量调节器(unified power quality conditioner, UPQC)在电网电压不平衡时,采用传统控制方法存在补偿效率和精确性较低的问题.针对这一情况,提出一种无源超螺旋二阶滑模控制策略.首先,基于MMC-UPQC的数学模型和无源控制理论,设计不平衡电网电压下基于欧拉-拉格朗日模型的正负序无源控制器;然后,加入超螺旋二阶滑模控制对无源控制器进行改善,抑制常规滑模存在的抖振,并解决无源控制对系统精度要求高的问题,提高系统的响应速度、补偿精度和抗干扰能力,提升系统的整体性能;最后,在Matlab/Simulink平台上进行仿真,并与PI控制和单独的无源控制对比,仿真结果验证了所提无源超螺旋二阶滑模控制策略的有效性和优越性.

关键词：模块化多电平换流器统一电能质量调节器电网电压不平衡无源超螺旋二阶滑模控制欧拉-拉格朗日模型

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