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Time to forge ahead:The Internet of Things for healthcare

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Digital Communications and Networks 2023年第1期9卷 223-235页

作者： Denzil furtado Andre f.Gygax Chien Aun Chan Ashley I.Bush Melbourne Dementia Research Centre&Department of Chemical Engineering University of MelbourneVIC3010Australia faculty of Business and Economics University of MelbourneVIC3010Australia Department of Electrical and Electronic Engineering University of MelbourneVIC3010Australia florey Institute of Neuroscience and Mental Health University of MelbourneVIC3010Australia

Situated at the intersection of technology and medicine,the Internet of Things(IoT)holds the promise of addressing some of healthcare's most pressing challenges,from medical error,to chronic drug shortages,to overburdened hospital systems,to dealing with the COVID-19 ***,despite considerable recent technological advances,the pace of successful implementation of promising IoT healthcare initiatives has been *** inspire more productive collaboration,we present here a simple—but surprisingly underrated—problemoriented approach to developing healthcare *** further assist in this effort,we reviewed the various commercial,regulatory,social/cultural,and technological factors in the development of the *** propose that fog computing—a technological paradigm wherein the burden of computing is shifted from a centralized cloud server closer to the data source—offers the greatest promise for building a robust and scalable healthcare IoT *** this end,we explore the key enabling technologies that underpin the fog architecture,from the sensing layer all the way up to the *** is our hope that ongoing advances in sensing,communications,cryptography,storage,machine learning,and artificial intelligence will be leveraged in meaningful ways to generate unprecedented medical intelligence and thus drive improvements in the health of many people.

关键词： Internet of Things Healthcare Information fog computing Artificial intelligence Machine learning Big data COVID-19 pandemic

Mechanical properties characterization of different types of masonry infill walls

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frontiers of Structural and Civil Engineering 2020年第2期14卷 411-434页

作者： Andre furtado Hugo RODRIGUES Antonio AREDE Humberto VARUM CONSTRUCT-LESE Department of Civil EngineeringFaculty of EngineeringUniversity of PortoPorto 4200-465Portugal R1SCO School of Technology and ManagementPolytechnic Institute of LeiriaLeiria 2411-901Portugal

It is remarkable,the recent advances concerning the development of numerical modeling frameworks to simulate the infill panels'seismic ***,there is a lack of experimental data of their mechanical properties,which are of full importance to calibrate the numerical *** primary objective of this paper is to present an extensive experimental campaign of mechanical characterization tests of infill masonry walls made with three different types of masonry units:lightweight vertical hollow concrete blocks and hollow clay *** different types of experimental tests were carried out,namely:compression strength tests,diagonal tensile strength tests,and flexural strength tests parallel and perpendicular to the horizontal bed joints.A total amount of 80 tests were carried out and are reported in the present *** second objective of this study was to compare the mechanical properties of as-built and existing infill *** results presented and discussed herein,will be in terms of strain-stress curves and damages observed within the *** was observed a fragile behavior in the panels made with hollow clay horizontal bricks,without propagation of *** plaster increased the flexural strength by 57%.

关键词： masonry infill walls experimental characterization compression strength shear diagonal strength flexural strength

Retreived bacteria from Noctiluca miliaris (green) bloom of the northeastern Arabian Sea

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Chinese Journal of Oceanology and Limnology 2013年第1期31卷 10-20页

作者： BASU Subhajit MATONDKAR SG Prabhu furtado Irene Department of Microbiology Goa University National Institute of Oceanography (CSIR-India)

In recent years, seasonal blooms of the dinoflagellate Noctiluca miliaris have appeared in the open-waters of the northern Arabian Sea （NAS）. This study provides the first characterization of bacteria from a seasonal bloom of green Noctiluca ofNAS （20°N-17°N and 64°E-70°E）, during the spring-inter-monsoon cruise ofSagar Sampada 253, in March 2007. Bacterial growth as assessed by most-probable number （MPN） and plate counts, revealed ＇variable-physiotypes＇ over a wide range of salinities （0%-25% w/v NaC1）, pH levels （5-8.5）, and organic nutrient strengths, in comparison to non-bloom waters. MPN indices of bacteria in surface waters of bloom stations ＊DWK and ＊PRB, corresponded to （3.08-4.41）×103 cells/mL at 3.5% NaC1 （w/v）, and （2.82-9.49）× 102 cells/mL at 25% （w/v） NaC1 in tryptone-yeast extract broth （TYE）. Plate counts were （1.12-4） × 106 CfU/mL at 0% （w/v） NaC1, （1.28-3.9） × 106 CfU/mL at 3.5% （w/v） NaC1, and （0.4- 7）×104 CfU/mL at 25% NaC1 （w/v） on TYE. One-tenth-strength Zobell＇s gave （0.6-3.74）× 105 CfU/mL at pH 5 to （3.58-7.5）× 105 CfU/mL at pH 8.5. These bacteria were identified to the genera Bacillus, Cellulomonas, Staphylococcus, Planococcus, Dietzia, Diergibacillus, Micrococcus, Sporosarcinae, Leucobacter, and Halomonas. The identity of three strains （GUfBSS253N2, GUfBSS253N30, and GUfBSS253N84） was confirmed through 16S rDNA sequence homology as Bacillus cohnii, Bacillusflexus, and Bacillus cereus. The -2-3-fold higher plate counts of culturable bacteria from the open-waters of the NAS indicate that these bacteria could critically determine the biogeochemical dynamics of the bloom and its milieu. The role of these bacteria in sustaining/terminating the bloom is under evaluation.

关键词： northeastern Arabian Sea (NAS) green Noctiluca bloom retrievable bacteria

Use of Targeted Orographic Smoothing in Very High Resolution Simulations of a Downslope Windstorm and Rotor in a Sub-tropical Highland Location

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Advances in Atmospheric Sciences 2023年第11期40卷 2043-2062页

作者： Peter SHERIDAN Anlun XU Jian LI Kalli furtado Met Office ExeterEX13PBUK Dali National Climate Observatory Dali 671003China State Key Laboratory of Severe Weather and Institute of Tibetan Plateau Meteorology Chinese Academy of Meteorological SciencesBeijing 100081China National Environment Agency Singapore

Nested simulations of a downslope windstorm over Cangshan mountain,Yunnan,China,have been used to demonstrate a method of topographic smoothing that preserves a relatively large amount of terrain detail compared to typical smoothing procedures required for models with terrain-following grids to run *** simulations were carried out using the Met Office Unified Model(MetUM)to investigate downslope *** smoothing method seamlessly blends two terrain datasets to which uniform smoothing has been applied—one with a minimum of smoothing,the other smoothed more heavily to remove gradients that would cause model *** latter dataset dominates the blend where the steepest slopes exist,but this is localised and recedes outside these *** a result,increased detail is starkly apparent in depictions of flow simulated using the blend,compared to one using the default *** includes qualitative flow details that were absent in the latter,such as narrow shooting flows emerging from roughly 1-2 km wide leeside *** separation is more common due to steeper lee *** use of targeted smoothing also results in increased lee side temporal variability at a given point during the windstorm,including over flat ***-/high-pass filtering of the wind perturbation field reveals that relative spatial variability above 30 km in scale(reflecting the background flow)is similar whether or not targeting is *** this scale,when smoothing is targeted,relative flow variability decreases at the larger scales,and increases at lower *** seems linked to fast smaller scale flows disturbing more coherent flows(notably an along-valley current over Erhai Lake).Spatial variability of winds in the model is unsurprisingly weaker at key times than is observed across a local network sampling mesoscale variation,but results are compromised due to relatively few observation locations sampling the *** when targeted smoothing is applied doe

关键词： lee wave turbulence mountain Tibetan Plateau aviation flow separation foehn complex terrain

Merging bound states in the continuum in an open acoustic resonator

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 124-131页

作者： Lujun Huang Bin Jia Artem S.Pilipchuk Sibo Huang Chen Shen Almas f.Sadreev Yong Li Andrey E.Miroshnichenko School of Physics and Electronic Sciences East China Normal University Institute of Acoustics Tongji University L.V.Kirensky Institute of Physics Department of Mechanical Engineering Rowan University School of Engineering and Technology University of New South Wales at Canberra

Bound states in the continuum （BICs） are perfectly localized resonances despite embedding in the continuum ***,an isolated BIC is very sensitive to the structure ***,we report merging acoustic BICs in a single open resonator,robust against the structure *** find that both symmetry-protected BIC and friedrich-Wintgen BIC are sustained in a single coupled waveguide-resonator *** varying the height and length of the resonator,these two BICs move toward each other and merge into a single one at a critical *** to an individual BIC,the merged BIC is robust against fabrication error because its Q-factor is proportional to ΔL-4,whereΔL embodies the structure *** essence of this extraordinary phenomenon is perfectly explained by the two-and three-level approximations of the effective nonHermitian ***,we present direct experimental demonstrations of the moving and merging of BICs in a coupled 3D waveguide-resonator,which are evidenced by the vanishing of the linewidth of fano resonance in the transmission *** results may find exciting applications in designing high-quality acoustic sources,sensors and filters.

关键词： acoustic resonances bound state in the continuum high-Q resonances

QTL mapping and identification of SNP-haplotypes affecting yield components of Theobroma cacao L.

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Horticulture Research 2020年第1期7卷 2444-2461页

作者： Luciel dos Santos fernandes fábio M.Correa Keith TIngram Alex-Alan furtado de Almeida Stefan Royaert Mars Center for Cocoa Science CP 55ItajuípeBA CEP 45.630-000Brazil Departamento de Ciências Biológicas Universidade Estadual de Santa CruzRodovia Ilhéus-ItabunaKm 16Bairro SalobrinhoIlhéusBA CEP 45.662-900Brazil Mars Incorporated13601 Old Cutler RoadMiamiFL 33158USA

Cacao is a crop of global relevance that faces constant demands for improved bean ***,little is known about the genomic regions controlling the crop yield and genes involved in cacao bean ***,to identify the quantitative trait loci(QTL)associated with cacao yield and bean filling,we performed a QTL mapping in a segregating mapping population comprising 459 trees of a cross between‘TSH 1188’and‘CCN 51’.All variables showed considerable phenotypic variation and had moderate to high heritability *** identified 24 QTLs using a genetic linkage map that contains 3526 single nucleotide polymorphism(SNP)*** analysis at the significant QTL region on chromosome IV pointed to the alleles from the maternal parent,‘TSH 1188’,as the ones that affect the cacao yield components the *** recombination events identified within these QTL regions allowed us to identify candidate genes that may take part in the different steps of pod growth and bean *** candidate genes seem to play a significant role in the source-to-sink transport of sugars and amino acids,and lipid metabolism,such as fatty acid *** SNP markers mapped in our study are now being used to select potential highyielding cacao varieties through marker-assisted selection in our existing cacao-breeding experiments.

关键词： breeding mapping linkage

Guest Editorial for Special Issue on Time Series Classification

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IEEE/CAA Journal of Automatica Sinica 2019年第6期6卷 1291-1292页

作者： Houshang Darabi Georgiana Ifrim Patrick Schafer Diego furtado Silva Department of Mechanical and Industrial Engineering University of Illinois at Chicago(UIC) University of Bucharest Romania University of Berlin Sciences(ICMC) University of Sao Paulo

TIME series classification research and applications have recently received a lot of *** the rapid advancement of technological devices,time series data are being collected by a wide variety of devices,resulting in a wide range of research and *** fields of studies,ranging from healthcare to weather readings,require time series *** and action recognition using time series data from fitness trackers are commonly being ***,a new generation of algorithms and techniques are being used to classify time series data that are extensively available to the research *** example,recently deep learning techniques that utilize convolutions and recurrent neural networks are being used to classify epileptic seizures from EEG recordings made available at the University of California-Irvine data repository.

关键词： classify utilize recording

Development of fish collagen in tissue regeneration and drug delivery

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Engineered Regeneration 2022年第3期3卷 217-231页

作者： Meison furtado Liang Chen Zehao Chen Ao Chen Wenguo Cui Department of Orthopaedics Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint DiseasesShanghai Institute of Traumatology and OrthopaedicsRuijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025P.R.China

Tissues rely on collagen for structural and biological integrity,as well as for function and *** collagen sources have been investigated due to its wide variety of applications,such as collagen from cows and ***,mammalian-based collagen has been limited by diseases like bovine spongiform encephalopathy(BSE)and other religious ***,fish collagen has caught the attention of the research community because it is easy to extract,has a high level of collagen content,excellent absorption properties,a low molecular weight,biocompatibility,little risk of disease transmission from animals to humans,negligible environmental contamination,and fewer ethical and religious concerns,posing as an ideal resource for product *** review focuses on the growing role of marine collagen in the advances of various biomedical applications,such as drug delivery,tissue engineering,regeneration,and wound healing,which will be covered in depth.

关键词： Collagen fish collagen Marine collagen Drug delivery Tissue engineering

Gut microbiome:A revolution in typeⅡdiabetes mellitus

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World Journal of Diabetes 2024年第9期15卷 1874-1888页

作者： Madhan Jeyaraman Tejaswin Mariappan Naveen Jeyaraman Sathish Muthu Swaminathan Ramasubramanian Gabriel Silva Santos Lucas furtado da fonseca Joséfábio Lana Department of Orthopaedics ACS Medical College and HospitalDr MGR Educational and Research InstituteChennai 600077Tamil NaduIndia Department of Orthopaedics Brazilian Institute of Regenerative MedicineIndaiatuba 13334-170São PauloBrazil Department of Orthopaedics Orthopaedic Research GroupCoimbatore 641045Tamil NaduIndia Department of Community Medicine Government Stanley Medical College and HospitalChennai 600001Tamil NaduIndia Department of Orthopaedics Government Medical CollegeKarur 639004Tamil NaduIndia Department of Biotechnology Faculty of EngineeringKarpagam Academy of Higher EducationCoimbatore 641021Tamil NaduIndia Department of Orthopaedics Government Medical CollegeOmandurar Government EstateChennai 600002Tamil NaduIndia

TypeⅡdiabetes mellitus(T2DM)has experienced a dramatic increase globally across countries of various income levels over the past three *** persistent prevalence of T2DM is attributed to a complex interplay of genetic and environmental *** numerous pharmaceutical therapies have been developed,there remains an urgent need for innovative treatment approaches that offer effectiveness without significant adverse *** this context,the exploration of the gut microbiome presents a promising *** has increasingly shown that the gut microbiome of individuals with T2DM exhibits distinct differences compared to healthy individuals,suggesting its potential role in the disease’s pathogenesis and *** emerging field offers diverse applications,particularly in modifying the gut environment through the administration of prebiotics,probiotics,and fecal microbiome *** interventions aim to restore a healthy microbiome balance,which could potentially alleviate or even reverse the metabolic dysfunctions associated with *** current results from clinical trials have not yet shown dramatic effects on diabetes management,the groundwork has been laid for deeper *** and future clinical trials are critical to advancing our understanding of the microbiome’s impact on *** further elucidating the mechanisms through which microbiome alterations influence insulin resistance and glucose metabolism,researchers can develop more targeted *** potential to harness the gut microbiome in developing new therapeutic strategies offers a compelling prospect to transform the treatment landscape of T2DM,potentially reducing the disease’s burden significantly with approaches that are less reliant on traditional pharmaceuticals and more focused on holistic,systemic health improvements.

关键词： TypeⅡdiabetes Gut microbiome Probiotics Prebiotics fecal microbiota transplantation