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Regression analysis of squeezing-induced hybrid nanofluid flow in Darcy-forchheimer porous medium

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 193-208页

作者： k.MUHAMMAD M.SARfRAZ Department of Humanities and Sciences School of Electrical Engineering and Computer Science National University of Sciences and Technology Department of Mathematics Quaid-i-Azam University

This article presents a mathematical model addressing a scenario involving a hybrid nanofluid flow between two infinite parallel plates. One plate remains stationary, while the other moves downward at a squeezing velocity. The space between these plates contains a Darcy-forchheimer porous medium. A mixture of water-based fluid with gold(Au) and silicon dioxide(Si O2) nanoparticles is formulated. In contrast to the conventional fourier's heat flux equation, this study employs the Cattaneo-Christov heat flux equation. A uniform magnetic field is applied perpendicular to the flow direction, invoking magnetohydrodynamic(MHD) effects. further, the model accounts for Joule heating, which is the heat generated when an electric current passes through the fluid. The problem is solved via NDSolve in MATHEMATICA. Numerical and statistical analyses are conducted to provide insights into the behavior of the nanomaterials between the parallel plates with respect to the flow, energy transport, and skin *** findings of this study have potential applications in enhancing cooling systems and optimizing thermal management strategies. It is observed that the squeezing motion generates additional pressure gradients within the fluid, which enhances the flow rate but reduces the frictional drag. Consequently, the fluid is pushed more vigorously between the plates, increasing the flow velocity. As the fluid experiences higher flow rates due to the increased squeezing effect, it spends less time in the region between the plates. The thermal relaxation, however, abruptly changes the temperature, leading to a decrease in the temperature fluctuations.

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Effects of P301L-TAU on post-translational modifications of microtubules in human iPSC-derived cortical neurons and TAU transgenic mice

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Neural Regeneration Research 2025年第8期20卷 2348-2360页

作者： Mohamed Aghyad Al kabbani Christoph köhler Hans Zempel Institute of Human Genetics Faculty of Medicine and University Hospital CologneUniversity of CologneCologneGermany Center for Molecular Medicine Cologne(CMMC) University of CologneCologneGermany Center Anatomy Department ⅡMedical FacultyUniversity of CologneCologneGermany

TAU is a microtubule-associated protein that promotes microtubule assembly and stability in the *** is missorted and aggregated in an array of diseases known as *** are essential for neuronal function and regulated via a complex set of post-translational modifications,changes of which affect microtubule stability and dynamics,microtubule interaction with other proteins and cellular structures,and mediate recruitment of microtubule-severing *** impairment of microtubule dynamics causes neuronal dysfunction,we hypothesize cognitive impairment in human disease to be impacted by impairment of microtubule *** therefore aimed to study the effects of a disease-causing mutation of TAU(P301L)on the levels and localization of microtubule post-translational modifications indicative of microtubule stability and dynamics,to assess whether P301L-TAU causes stability-changing modifications to *** investigate TAU localization,phosphorylation,and effects on tubulin post-translational modifications,we expressed wild-type or P301L-TAU in human MAPT-kO induced pluripotent stem cell-derived neurons(i Neurons)and studied TAU in neurons in the hippocampus of mice transgenic for human P301L-TAU(p R5 mice).Human neurons expressing the longest TAU isoform(2N4R)with the P301L mutation showed increased TAU phosphorylation at the AT8,but not the p-Ser-262 epitope,and increased polyglutamylation and acetylation of microtubules compared with endogenous TAU-expressing neurons.P301L-TAU showed pronounced somatodendritic presence,but also successful axonal enrichment and a similar axodendritic distribution comparable to exogenously expressed 2N4R-wildtype-TAU.P301L-TAU-expressing hippocampal neurons in transgenic mice showed prominent missorting and tauopathy-typical AT8-phosphorylation of TAU and increased polyglutamylation,but reduced acetylation,of microtubules compared with non-transgenic *** sum,P301L-TAU results in changes in micr

关键词： human induced pluripotent stem cell microtubules P301L pR5 mice TAU tauopathy tubulin code

Influence of Individual Characteristics on Consumer Understanding and Using of Nutrition fact Panel-Case Study of Zambia and China

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Influence of Individual Characteristics on Consumer Understa...

作者：罗尼卡（Veronica mulenga）东南大学

学位级别：硕士

目的：为了解中国和赞比亚消费者在多大程度上理解和使用营养标示栏,并评价选择食物时使用营养标示栏(NfP)的影响因素水平。方法：分别从南京和利文斯敦的两个国际都市募集498名中国消费者和325名赞比亚消费者。使用购物中心现场采访调... 详细信息

目的：为了解中国和赞比亚消费者在多大程度上理解和使用营养标示栏,并评价选择食物时使用营养标示栏(NfP)的影响因素水平。方法：分别从南京和利文斯敦的两个国际都市募集498名中国消费者和325名赞比亚消费者。使用购物中心现场采访调查技术,在中国的主要食品超市如麦德龙、沃尔玛、苏果,在赞比亚的斯帕尔、绍普莱特附近对消费者进行方便的抽样,并使用结构式问卷进行调查。选择18岁及以上的参与者。性别、年龄、教育程度、职业、收入、家庭人数和健康状况是自变量,消费者阅读和理解NfP是应变量。数据统计参用卡方检验法分析研究结果。结果：记录了中国(58.7%)和赞比亚(67.1%)消费者意识并阅读NfP信息的平均水平。此外,卡方检验揭示基于性别的统计学差异。在两个地区更多女性(中国65.3%,赞比亚74.4%)消费者都比男性消费者(中国51.1%,赞比亚60.9%)在使用NfP上意识性更强。使用NfP的消费者大多是中年人(31-45岁和46-50岁)。并且中等及以上教育水平的消费者对NfP有更高的意识和理解水平。在中国和赞比亚,当消费者属于医学领域、工程师、商人、教师和家庭主妇,则会更多地使用NfP。调查结果显示两地家庭对NfP知晓度产生的影响具有显著性差异。在中国的家庭比赞比亚的家庭更有意识使用NfP。至于收入,在中国那些高收入的消费者比低收入使用NfP更多,而在赞比亚所有收入水平使用度平均分布。健康状况代表个人或任何一名家庭成员当前的健康状况,在中国,健康状况这一变量在意识和阅读NfP上有积极影响,存在健康问题的消费者(72.6%)比那些没有健康问题的消费者会更多的使用NfP。由于结果没有统计学意义,这种情况在赞比亚并非如此。结论：NfP的知晓度和使用存在的多样性主要是由于个人特征的影响。这些个人特征可能促进消费者使用NfP(如受过更高教育的个体意识并使用NfP的可能性更高),或对消费者产生负面影响(较低或未受教育的消费者不太可能意识到使用NfP)。性别、教育和职业对中国和赞比亚的消费者都具有积极影响。收入水平和家庭人数对中国消费者具有积极的影响,但赞比亚的消费者无此效应。健康状况也积极影响着中国消费者使用NfP,而赞比亚消费者却不是这样。结果表明,需要发展项目旨在提高NfP信息的意识水平,以确保发展健康的消费习惯。特别是那些不知道并混淆NfP成分表,在意食品标签的其他组分而忽略了NfP的高比例的消费者。这也将确保消费者明智选择食物,避免饮食相关的疾病。

关键词：营养标示栏知晓度运用影响因素

Mathematical Model of Classical kaposi’s Sarcoma

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Applied Mathematics 2020年第7期11卷 579-600页

作者： Obias mulenga Chimbola Department of Mathematics and Statistical Sciences Botswana International University of Science and Technology Palapye Botswana Department of Mathematics and Statistics Mulungushi University Kabwe Zambia

In this paper, the global properties of a classical kaposi’s sarcoma model are investigated. Lyapunov functions are constructed to establish the global asymptotic stability of the virus free and virus (or infection) present steady states. The model considers the interaction of B and progenitor cells in the presence of HHV-8 virus. And how this interaction ultimately culminates in the development of this cancer. We have proved that if the basic reproduction number, R0 is less than unity, the virus free equilibrium point, ε0, is globally asymptotically stable (GAS). We further show that if R0 is greater than unity, then both the immune absent and infection persistent steady states are GAS.

关键词： Human Herpesvirus-8 Lyapunov function Classical kaposi’s Sarcoma

Human endogenous retrovirus type-W and multiple sclerosis–related smoldering neuroinflammation

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Neural Regeneration Research 2025年第3期20卷 813-814页

作者： Joel Gruchot Laura Reiche Andrew Chan Robert Hoepner Patrick küry Department of Neurology Medical Faculty and University Hospital DüsseldorfHeinrich Heine University DüsseldorfDüsseldorfGermany Department of Neurology InselspitalBern University Hospital and University of BernBernSwitzerland

Introduction to human endogenous retrovirus type-W(HERV-W): Genomic inheritance from the past includes retroviral sequences that have been stably incorporated into our genomes and account for up to 8% of human DNA.

关键词： endogenous inflammation Human

Nucleoside modified mRNA-lipid nanoparticles as a new delivery platform for the repair of the injured spinal cord

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Neural Regeneration Research 2025年第8期20卷 2311-2312页

作者： krisztián Pajer Tamás Bellák Antal Nógrádi Department of Anatomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary

Spinal cord injury and treatment opportunities:The adult mammalian spinal cord has a very limited capacity for spontaneous regeneration due to various intrinsic molecular and cellular *** the spinal cord neurons have the capacity to regenerate their axons,the expression of growth inhibitory factors,lack or suppression of proper guidance cues,and profound inflammatory responses do not permit successful regeneration(khyeam et al.,2021).

关键词： injured capacity modified

Biofuel-driven trigeneration systems for non-residential building applications:A holistic assessment from the energy,environmental and economic perspectives

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Building Simulation 2023年第4期16卷 557-576页

作者： k.f.fong C.k.Lee Division of Building Science and Technology College of EngineeringCity University of Hong KongTat Chee AvenueKowloonHong KongChina

In the metropolises,it is unlikely to use merely solar and wind energy to pursue zero carbon building ***,it would become possible if biofuel-driven trigeneration systems(BDTS)are *** is thus essential to assess the application opportunity of BDTS in a holistic *** this study,BDTS offered definite primary energy saving of up to 15%and carbon emissions reduction of at least 86%in different types of non-residential buildings as compared to the conventional *** 24/7 operation for the hotel and hospital buildings,the corresponding BDTS could even achieve zero carbon *** the BDTS primed with compression-ignition internal combustion engine were not economically viable even in running cost due to the high local biodiesel price *** BDTS primed with spark-ignition engine and fueled by biogas,however,would have economic merit when carbon price was considered for the conventional systems that fully utilize fossil *** of carbon tax and social cost could have the payback ceilings of 8 years and 2 years respectively for most of building ***,the results could reflect the application potential of BDTS for non-residential buildings,leading the pathway to carbon neutrality for sustainable sub-tropical cities.

关键词： trigeneration biofuel dynamic simulation carbon tax social cost economic analysis

Mathematical Model of HIV-1 Dynamics with T Cell Activation

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Journal of Applied Mathematics and Physics 2020年第7期8卷 1328-1345页

A deterministic in-host model of HIV-1 that incorporates naive and activated T cells is being investigated. The model represents the dynamics of five subsets of T cells and one class of HIV-1. The virus free and the infection persistent equilibria are found and their stability analysed. With the aid of suitable Lyapunov functionals, we have shown that the model equilibria are globally asymptotically stable under special conditions. The numerical simulation is performed to illustrate both the short term and long term dynamics of HIV-1 infection. The results of simulation are in agreement with published data with regard to CD4+ T cell concentration and the viral load.

关键词： HIV-1 T Cell Lyapunov function Global Stability

Teleportation of unknown states of a qubit and a single-mode field in strong coupling regime without Bell-state measurement

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Communications in Theoretical Physics 2023年第2期75卷 73-79页

作者： f Jahanbakhsh M k Tavassoly Optics and Laser Group Faculty of PhysicsYazd UniversityYazd 89195-741Iran

In this paper,we develop the teleportation scheme in[Zheng in Phys Rev A 69,064302,2004],in the sense that,we work in the strong atom-field coupling regime wherein the rotating wave approximation(RWA)is no longer *** achieve the purpose,a scheme consisting of a qubit interacting with a single-mode quantized field is described via the Rabi model(counter rotation terms are taken into account).Our first aim is to teleport an unknown atomic state of a qubit(which interacts with the quantized field in a cavity)to a second qubit(exists in another distant cavity field),beyond the RWA and without the Bell-state measurement *** the continuation,in a similar way,we teleport an unknown state of a single-mode field *** fact,it is shown that,in this regime,after applying some particular conditions,containing the interaction time of atom-field in the cavities,adjusting the involved frequencies,as well as the atom-field coupling in the model,if a proper measurement is performed on the state of the first qubit(the related field in the cavity),the unknown states of the qubit(field)can be teleported from the first qubit(cavity field)to the second qubit(cavity field),*** show that in both considered cases,the teleportation protocol is successfully performed with the maximum possible fidelity,1,and the acceptable success probability,0.25.

关键词： strong atom-field coupling Rabi model quantum teleportation success probability fidelity