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Design of a Prototype EHD Air Pump for Electronic Chip Cooling Applications

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Plasma Science and Technology 2014年第5期16卷 491-501页

作者： emmanouil D.FYLLADITAKIS Antonios X.MORONIS Konstantinos KIOUSIS Technological Educational Institute(TEI) of Athens Department of Energy Technology

This paper presents the design,optimization and fabrication of an EHD air pump intended for high-power electronic chip cooling *** high-voltage electrode configurations were selected and studied,in terms of the characteristics of the generated electric field,which play an important role in ionic wind *** this purpose,dedicated software is used to implement finite element *** design parameters,such as the electric field intensity,wind velocity,current flow and power consumption are *** different laboratory prototypes are fabricated and their performances experimentally *** procedure leads to the fabrication of a final prototype,which is then tested as a replacement of a typical fan for cooling a high power density electronic *** assist towards that end,an experimental thermal testing setup is designed and constructed to simulate the size of a personal computer’s CPU core of variable *** parametric study leads to the fabrication of experimental single-stage EHD pumps,the optimal design of which is capable of delivering an air flow of 51 CFM with an operating voltage of 10.5 ***,the theoretical and experimental results are evaluated and potential applications are proposed.

关键词： electrohydrodynamics(EHD) ionic wind EHD pump cooling apparatus finite element method computer CPU cooling electronic chip cooling

Gut microbiome dysbiosis in the setting of solid organ transplantation:What we have gleaned from human and animal studies

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World Journal of Transplantation 2022年第7期12卷 157-162页

作者： Aparna Sharma emmanouil Giorgakis Department of Nephrology University of Arkansas for Medical SciencesLittle RockAR 72223United States Department of Surgery University of Arkansas for Medical SciencesLittle RockAR 72223United States

The human gut microbiome refers to all of the microorganisms present throughout the length of the gastrointestinal *** flora influence host metabolic and immune processes in myriad *** also play an important role in maturation and modulation of the immune *** or a pathologic alteration in gut flora has been implicated in a number of diseases ranging from metabolic,autoimmune and *** dysbiosis has similar implications in organ transplant has been the focus of a number of pre-clinical and clinical *** have observed significant microbiome changes after solid organ transplantation in humans that have been associated with clinical outcomes such as post-transplant urinary tract infections and *** this article,we will discuss the available data regarding pathologic alterations in gut microbiome(dysbiosis)in solid organ transplant recipients as well as some of challenges in this *** will also discuss animal studies focusing on mouse models of transplantation that shed light on the underlying mechanisms that explain these findings.

关键词： Dysbiosis Gut microbiome Innate immunity Short chain fatty acids Toll like receptors Tolerance

A combined risk-based and condition monitoring approach:developing a dynamic model for the case of marine engine lubrication

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Transportation Safety and Environment 2022年第3期4卷 74-87页

作者： Nikolaos P.Ventikos Panagiotis Sotiralis emmanouil Annetis School of Naval Architecture and Marine Engineering National Technical University of Athens9 Iroon Politechneiou St15773ZografouGreece.

This paper focuses on the creation of a dynamic probabilistic model which simulates deterioration trends of a marine engine lubricationsystem. The approach is based on risk and the implementation is achieved through a dynamic Bayesian network (dBN).Risk can be useful for decision making, while dBNs are a powerful tool for risk modelling and prediction models. The model takesinto account deterioration of engine components, oil degradation and the off-line condition monitoring technique of oil analysis, inthe context of predictive maintenance. The paper aims to efficiently predict probability evolution for main engine lubrication failureand to decide upon the most beneficial schemes from a variety of lubrication oil analysis interval schemes by introducing monetarycosts and producing the risk model. Real data and respective analysis, along with expert elicitation, are utilized for achieving modelquantification, while themodel is materialized through a code in the Matlab environment. Results from the probabilistic model showa realistic simulation for the system and indicate the obvious, that with more frequent oil analyses and respective maintenance orrepairs, the probability of failure drops significantly. However, the results from the risk model highlight that the costs can redefinescheme suggestions, as they can correspond to low probabilities of failure but also to higher costs. A two-month interval scheme issuggested, in contrast to the most preferred practice among shipping companies of a three-month interval. The developed model isin general identified as a failure prediction tool focusing on marine engine lubrication failure.

关键词： Risk modelling dynamic Bayesian networks(dBNs) condition monitoring predictive maintenance marine engine lubrication oil analysis deterioration model

Effects of local compositional and structural disorder on vacancy formation in entropy-stabilized oxides from first-principles

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npj Computational Materials 2022年第1期8卷 909-915页

作者： Sieun Chae Logan Williams Jihang Lee John T.Heron emmanouil Kioupakis Department of Materials Science and Engineering University of MichiganAnn ArborMIUSA

Entropic stabilization has evolved into a strategy to create new oxide materials and realize novel functional properties engineered through the alloy *** an atomistic understanding of these properties to enable their design,however,has been challenging due to the local compositional and structural disorder that underlies their fundamental structure-property ***,we combine high-throughput atomistic calculations and linear regression algorithms to investigate the role of local configurational and structural disorder on the thermodynamics of vacancy formation in (MgCoNiCuZn)O-based entropy-stabilized oxides (ESOs) and their influence on the electrical *** find that the cation-vacancy formation energies decrease with increasing local tensile strain caused by the deviation of the bond lengths in ESOs from the equilibrium bond length in the binary *** oxygen-vacancy formation strongly depends on structural distortions associated with the local configuration of chemical *** in ESOs exhibit deep thermodynamic transition levels that inhibit electrical *** applying the charge-neutrality condition,we determine that the equilibrium concentrations of both oxygen and cation vacancies increase with increasing Cu mole *** results demonstrate that tuning the local chemistry and associated structural distortions by varying alloy composition acts an engineering principle that enables controlled defect formation in multi-component alloys.

关键词： alloy structural vacancy

Exploring Barriers and Opportunities in Adopting Crowdsourcing Based New Product Development in Manufacturing SMEs

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Chinese Journal of Mechanical Engineering 2016年第6期29卷 1052-1066页

作者： QIN Shengfeng David VAN der VELDE emmanouil CHATZAKIS Terry McSTEA Neil SMITH School of Design Northumbria University Newcastle upon Tyne NE1 3PH UK Consult and Design International Sunderland SR1 1PB UK School of Arts & Media Teesside University Middlesbrough TS1 3BX UK RTCNorth Northern Design Centre Gateshead Tyne and Wear NE8 3DE UK

Crowdsourcing is an innovative business practice of obtaining needed services, ideas, or content or even funds by soliciting contributions from a large group of people （the ＇Crowd＇）. The potential benefits of utilizing crowdsourcing in product design are well-documented, but little research exists on what are the barriers and opportunities in adopting crowdsourcing in new product development （NPD） of manufacturing SMEs. In order to answer the above questions, a Proof of Market study is carried out on crowdsourcing-based product design under an Innovate UK funded Smart project, which aims at identifying the needs, challenges and future development opportunities associated with adopting crowdsourcing strategies for NPD. The research findings from this study are reported here and can be used to guide future development of crowdsourcing-based collaborative design methods and tools and provide some practical references for industry to adopt this new and emerging collaborative design method in their business.

关键词： new product development open design innovation collaborative design crowdsourcing manufacturing SMEs

Frequency-based control of islanded microgrid with renewable energy sources and energy storage

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Journal of Modern Power Systems and Clean Energy 2016年第1期4卷 54-62页

作者： Konstantinos O.OUREILIDIS emmanouil A.BAKIRTZIS Charis S.DEMOULIAS Department of Electrical and Computer Engineering Aristotle University of ThessalonikiThessaloniki 54124Greece

When a microgrid is mainly supplied by renewable energy sources(RESs), the frequency deviations may deteriorate significantly the power quality delivered to the loads. This paper proposes a frequency-based control strategy, ensuring the frequency among the strict limits imposed by the Standard EN 50160. The frequency of the microgrid common AC bus is determined by the energy storage converter, implementing a proposed droop curve among the state of charge(SoC) of the battery and the frequency. Therefore, the information of the SoC becomes known to every distributed energy resource(DER) of the microgrid and determines the active power injection of the converter-interfaced DERs. The active power injection of the rotating generators remains unaffected, while any mismatch among the power generation and consumption is absorbed by the energy storage system. Finally, in case of a solid short-circuit within the microgrid, the energy storage system detects the severe voltage decrease and injects a large current in order to clear the fault by activating the protection device closer to the fault. The proposed control methodology is applied in a microgrid with PVs, wind generators and a battery, while its effectiveness is evaluated by detailed simulation tests.

关键词： Microgrid Frequency control Renewable energy sources Energy storage system SoC control

Surface Nanopatterning Using the Self-Assembly of Linear Polymers on Surfaces after Solvent Evaporation

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Nanomanufacturing and Metrology 2022年第3期5卷 297-309页

作者： emmanouil Glynos Alexandros Chremos Philip J.Camp Vasileios Koutsos School of Engineering Institute for Materials and ProcessesTheUniversity of EdinburghRobert Stevenson RoadEdinburgh EH93FBUK School of Chemistry The University of EdinburghDavid Brewster RoadEdinburgh EH93FJUK Department of Materials Science and Technology University of Crete71003 HeraklionGreece Section on Quanitative Imaging and Tissue Sciences Eunice Kennedy Shriver National Institute of Child Health and Human DevelopmentNational Institutes of HealthBethesdaMD 20892USA

The morphology of linear polybutadiene physisorbed on freshly cleaved mica from a dilute polymer solution is investigated through atomic force microscopy.A fine-structure study shows that the monolayer morphology in air(after rapid solvent evaporation)depends strongly on the molecular weight(Mw)of the linear polymer,the adsorbed amount,and the conformation adopted by the adsorbed polymer chains under good solvent *** dependence of the observed polymer structure on Mw is most significant for samples with high surface density,where the intermolecular interactions among the adsorbed polymers are *** high surface density,the adsorbed polymers tend to aggregate and minimize unfavorable contacts with air for all of the different Mw samples,leading to an isotropic structural *** structural phenomena with increasing surface density are explained on the basis of the intermolecular interactions of the adsorbed polymers under good solvent conditions,and after the abrupt solvent evaporation corresponding to poor solvent *** experimental observations are further discussed using the results obtained from molecular dynamics simulations of a simple coarse-grained model.

关键词： Surface nanopatterning Self-assembly Nanomanufacturing

Beta-blocker treatment in heart failure patients with atrial fibrillation:challenges and perspectives

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Journal of Geriatric Cardiology 2021年第5期18卷 362-375页

作者： emmanouil Chourdakis Ioanna Koniari Dimitrios Velissaris Grigorios Tsigkas Nikolaos G Kounis Neriman Osman Krankenhaus der Barmherzigen Brüder Trier Germany Manchester Heart Institute Manchester University Foundation TrustManchesterUnited Kingdom Department of Internal Medicine University Hospital of PatrasPatrasGreece Cardiology Department University Hospital of PatrasPatrasGreece

Heart failure(HF)and atrial fibrillation(AF)are common conditions that share similar clinical phenotype and frequently *** classification of HF in patients with preserved ejection fraction(>50%,HFpEF),midrange reduced EF(40%−49%,HFmrEF)and reduced EF(<40%,HFrEF)are crucial for optimising the therapeutic approach,as each subgroup responds *** constitute an important component of our pharmacological regimen for chronic *** administration is reccomended in patients with HF with reduced ejection fraction in stable sinus rhythm,due to improvement of symptoms,the better long termoutcome and *** beneficial role of betablocker use in patients with preserved EF still remain unclear,as no treatment showed a positive impact,regarding morbidity or mortality *** presence of AF in HF patients increases as the disease severity evolves and is associated with a higher rate of cardiovascular morbidity and *** more question is the use of betablocker in HF patients irrespective of EF and concomitant *** are many conflicting data and publications,regarding the beta blocker benefit in this ***,it is supported an attenuation of betablockers beneficial effect in HF patients with AF.A design of more randomised trials/studies with HF patients and concomitant AF may improve our clinical approach of betablockers use and identify the patients with HF,who mostly profit from an invasive approach.

关键词： treatment evolve mostly

Update on the association of hepatitis B with intrahepatic cholangiocarcinoma:Is there new evidence?

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World Journal of Gastroenterology 2021年第27期27卷 4252-4275页

作者： Nikolaos Fragkou Lazaros Sideras Panteleimon Panas Christos emmanouilides emmanouil Sinakos Fourth Department of Internal Medicine Aristotle University of ThessalonikiThessaloniki 54642Greece Department of Oncology Interbalkan Medical CenterThessaloniki 57001Greece

Intrahepatic cholangiocarcinoma(iCCA)is a subgroup of cholangiocarcinoma that accounts for about 10%-20%of the total *** with hepatitis B virus(HBV)is one of the most important predisposing factors leading to the formation of *** has been recently estimated based on abundant epidemiological data that the association between HBV infection and iCCA is strong with an odds ratio of about *** HBV-associated mechanisms that lead to iCCA are under intense *** diagnosis of iCCA in the context of chronic liver disease is challenging and often requires histological confirmation to distinguish from hepatocellular *** is currently unclear whether antiviral treatment for HBV can decrease the incidence of *** terms of management,surgical resection remains the mainstay of *** is a need for effective treatment modalities beyond resection in both first-and second-line *** this review,we summarize the epidemiological evidence that links the two entities,discuss the pathogenesis of HBV-associated iCCA,and present the available data on the diagnosis and management of this cancer.

关键词： Cholangiocarcinoma Hepatitis B Intrahepatic Hepatocellular carcinoma Resection Chemotherapy