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Serum vitamin D content is associated with semen|parameters and serum testosterone levels in men

Asian Journal of Andrology 2021年第1期23卷 52-58页

作者： Inari M Ciccone elaine mf costa Juliana R Pariz Thiago A Teixeira Joel R Drevet Parviz Gharagozloo Robert J Aitken Jorge Hallak Androscience Science and Innovation Center in Andrology and High-Complex Clinical and Andrology LaboratorySao Paulo 04534-011Brazil Division of Urology University of Sao PauloSao Paulo 05403-000Brazil Men's Health Study Group Institute for Advanced StudiesUniversity of Sao PauloSao Paulo 05508-060Brazil Division of Endocrinology University of Sao PauloSao Paulo 05403-000Brazil School of Medicine Urology DepartmentFederal University of AmapaMacapa 68903-419Brazil Faculty of Medicine GReD LaboratoryUniversity Clermont Auvergne49Bd Frangois-Mitterrand-CS 6003263001 Clermont-Ferrand CedexFrance Cell0xess LLC EwingNJ 08628USA School of Environmental and Life Sciences Priority Research Centre for Reproductive SciencesUniversity of NewcastleCallaghanNSW 2308Australia Reproductive Toxicology Unit Department of PathologyUniversity of Sao PauloSao Paulo 05403-000Brazil

The present study aimed to evaluate the influence of serum vitamin D levels on semen quality and testosterone *** is a crosssectional study conducted at Androscience,Science and Innovation Center in Andrology and High-Complex Clinical and Andrology Laboratory in Sao Paulo,Brazil,with 508 male patients,aged 18-60 years,from 2007 to *** parameters and serum sexual hormones were correlated with serum vitamin D concentrations in 260 men selected by strict selection *** were divided into normozoospermic group(NZG,n=124)and a group with seminal abnormalities(SAG,n=136).Evaluation included complete physical examination,past medical history,habits and lifestyle factors,two complete seminal analysis with sperm functional tests,serum levels of 25-hydroxy-vitamin D_(3)(25(OH)VD_(3)),total and free testosterone,luteinizing hormone(LH),follicle-stimulating hormone(FSH),sex hormone-binding globulin(SHBG),total cholesterol,homeostatic model assessment of insulin resistance(HOMA-IR)index,and *** mean concentration of 25(OH)VD_(3)was significantly lower in the SAG(P<0.001)and positively correlated with all baseline seminal parameters and total testosterone *** addition,serum vitamin D_(3)concentration was found to be positively correlated with sperm concentration(β=2.103;P<0.001),total number of spermatozoa with progressive motility(β=2.069;P=0.003),total number of motile spermatozoa(β=2.571;P=0.015),and strict morphology(β=0.056;P=0.006),regardless of other *** is the first comparative study to address the issue of serum vitamin D_(3)content between normozoospermic patients and those with sperm *** clearly demonstrates a direct and positive relationship between serum vitamin D level and overall semen quality,male reproductive potential,and testosterone levels.

关键词： male infertility semen quality sexual hormones sperm motility testosterone vitamin D deficiency

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Ergatoid reproductives in the Neotropical termite Nasutitermes aquilinus (Holmgren) (Blattaria: Isoptera: Termitidae): developmental origin, fecundity, and genetics

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Insect Science 2020年第6期27卷 1322-1333页

作者： Iago Bueno da Silva Ives Haifig Edward LVargo Fabiana elaine Casarin Marcelo Luiz da Mota Juliana Toledo Lima Ana Maria costa-Leonardo Laboratorio de Cupins Departamento de BiologiaInstituto de BiocienciasUniversidade Estadual Paulista-UN ESPRio ClaroSPBrazil Centro de Ciencias Naturais e Humanas Universidade Federal do ABCSao Bernardo do CampoSPBrazil Department of Entomology Texas A&M UniversityCollege StationTexasUSA Departamento de Ciencias Biologicas Universidade Federal de Sao Paulo-UNIFESPDiademaSPBrazil Instituto de Ciencias Agrarias Universidade Federal de Uberlandia—UFUMonte CarmeloMGBrazil Centro de Estudos em Recursos Naturais Universidade Estadual de Mato Grosso do SulDouradosMSBrazil

Termite colonies are usully headed by primary reproductives,which estab-listh nests during the swar ming ***,secondary reproductives may develop in some specics and become supplementary or replacement breeders,extending colony *** we investigate the developmental origin,fecundity and genetic characterizaion of ergatoid reproductives in the Neotropical termite Nasuitermes aquilinus(Holmgren),using morphometrical and histological techniques,five micosiallitle loci and the COI mitochondrial *** measurements performed on 208 apterous individuals of Nuauidius revealed 10 groups,including ergatoid females,which developed from major workers through two successive *** were characterized by the presence of imaginal features such as eyes andl wing *** difentiation of these features was correlated to physogastric development in these ergatoids,Histology revealed ooeytes in all matu-ration sages in worker-derived reproductives of N aquidinus,presence of nonflagellate spermatozoa inside the spermatheea,and royal fa ***,ergatoid reproduwetives were reproductively *** to the genotypes of 221 individuals from 11 nests,and mitochondrial haplotypes of 43 ergatoids,73%of the colomies were simple families,whereas 27%were extendbed *** the oecurenee of related reproductives,low inbreeding rates were detected within and among *** values could be explained given that sib mating itself cannot result in a higher inbreeding rate but depend on several factors discussed in *** is the first study to investigate the genetic structure of termite colonies influenced by the development of ergatoids and further investigations are encouraged 10 understand the inflwence of these reproductives on colony lifespan.

关键词： breeding syslem caste ifrentiation COI genotyping micosallites reproduction

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Ntic and Teenagers in the South： Case of High-School Students in Recife, Aignan, and Hanoi

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Psychology Research 2017年第12期7卷 627-638页

作者： elaine Magalhaes costa Femandez Tran Thu Huong Trinh Thi Linh Federal University of Pernambuco (UFPE) Recife Brazil University of Social Sciences and Humanities (USSH) of Hanoi Hanoi Vietnam

From the work on the Eurocentric critical thinking and on the territorialisation of the Internet, three researchers will present the theoretical and epistemological bases of an international research on the intercultural aspects of the impact of the New Technologies of Information and Communication (NTIC) on the process of socialization and subjectivation of high-school students from three continents. It will be the issues of a methodological triangulation based on the ecology of knowledge and the intercultural perspective, in the respect for the cultural context of the participants, their pluralities and particular isms. Online questionnaire consisting of 50 questions was developed in Portuguese in Brazil and translated according to the method of trans-cultural adaptation in French and then in Vietnamese. It will be a question of a critical analysis of the construction and validation of the instrument, its cross-cultural adaptations, as well as the method of result analysis through the Program Statistical Package for the Social Sciences (SPSS), the objective of which is to describe the modalities of use of social networks, and video games of high-school students in Hanoi. Thus it is hoped to compare the characteristics of the population studied (number, age, schooling, and sexes), the rhythm and modalities of use of video games and social networks, the relationships between different members of the family and their peers, to the data of the other two populations studied. The parallel between the data obtained in Vietnam, France, and Brazil will contribute to the understanding on the part of the context and the cultural affiliation in the establishment of relationships between the users and the NTIC and consequently to the definition of the methods of prevention of risks more adapted to the realities of young people and their families.

关键词：中学生大小写南方少年社会科学视频游戏跨文化研究人员

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Deficit Irrigation as a Strategy to Save Water:Physiology and Potential Application to Horticulture

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Journal of Integrative Plant Biology 2007年第10期49卷 1421-1434页

作者： J.Miguel costa Maria F.Ortuo M.Manuela Chaves InstitutoSuperior de Agronomia Universidade Técnica de LisboaTapada da Ajuda1349-017 LisboaPortugal Laboratório de Ecofisiologia MolecularInstituto de Tecnologia Química e BiológicaApartado 1272780-901 OeirasPortugal Instituto

Water is an increasingly scarce resource worldwide and irrigated agriculture remains one of the largest and most inefficient users of this resource. Low water use efficiency （WUE） together with an increased competition for water resources with other sectors （e.g. tourism or industry） are forcing growers to adopt new irrigation and cultivation practices that use water more judiciously. In areas with dry and hot climates, drip irrigation and protected cultivation have improved WUE mainly by reducing runoff and evapotranspiration losses. However, complementary approaches are still needed to increase WUE in irrigated agriculture. Deficit irrigation strategies like regulated deficit irrigation or partial root drying have emerged as potential ways to increase water savings in agriculture by allowing crops to withstand mild water stress with no or only marginal decreases of yield and quality. Grapevine and several fruit tree crops seem to be well adapted to deficit irrigation, but other crops like vegetables tend not to cope so well due to losses in yield and quality. This paper aims at providing an overview of the physiological basis of deficit irrigation strategies and their potential for horticulture by describing the major consequences of their use to vegetative growth, yield and quality of different crops （fruits, vegetables and ornamentals）.

关键词： deficit irrigation horticulture partial rootzone drying regulated deficit irrigation water saving.

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Application of Non-destructive Testing to Evaluate the Performance of Bridges Structures

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Journal of Civil Engineering and Architecture 2017年第1期11卷 1-7页

作者： Diego Jesus de Souza elaine Souza dos Santos Eric Pianizolli Flor Gabriel Pereira Marinho Giovana costa Reus Heloise Cristine Cezario Leticia Andrade Camara Department of Civil Engineering University of Ottawa Ottawa K2P0M1 Canada Department of Civil Construction Universidade Federal do Parana Sao Jose dos Pinhais 83040-334 Brazil Department of Civil Construction Universidade Federal do Parana Linhares 29902-190 Brazil Department of Civil Construction Universidade Federal do Parana Curitiba 80630-280 Brazil Department of Civil Construction Universidade Federal do Parana Campo Largo 83604-230 Brazil Department of Civil Construction Universidade Federal do Parana Curitiba 80060-120 Brazil

Bridges are important elements in road system and can influence the entire economy of cities and region. Usually, these structures have high financial investments for their constructions, in this way, maintenance and conservation become so important. Inspection is a technical activity that covers several operations, including performance analysis; examination; final performance report, other operations may be necessary, such as maintenance work, recovery, strengthening and rehabilitation. Technical examination together with some test methods allows a critical and parametric judgment of the bridge performance by minimizing the subjectivity of visual evaluations, and permits a more detailed diagnosis. This paper discusses the methodology to perform tests to complement the assessment recommended by DNIT （Brazilian National Department of Transport Infrastructure）, which consists only on a visual judgment. This approach provides technical basis to classify the bridges as its need and urgency of maintenance.

关键词： Non-destructive testing bridges concrete durability.

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Hepatobiliary phases in magnetic resonance imaging using liverspecific contrast for focal lesions in clinical practice

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World Journal of Hepatology 2022年第7期14卷 1459-1469页

作者： Daniel Alvarenga Fernandes Eduardo Andreazza Dal Lago Felipe Aguera Oliver Bruna Melo Coelho Loureiro Daniel Lahan Martins Thiago José Penachim Ricardo Hoelz de Oliveira Barros José de ArimatéiaBatista Araújo Filho Larissa Bastos Eloy da costa Áurea Maria Oliveira da Silva elaine Cristina de Ataíde Ilka de Fátima Santana Ferreira Boin Nelson Marcio Gomes Caserta Department of Radiology School of Medical SciencesUniversity of Campinas-UNICAMPCampinas 13083-888São PauloBrazi Department of Radiology Medical SchoolSão Paulo State University-UNESPBotucatu 18618-970São PauloBrazil Instituto de Radiologia Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo-InRad/HC-FMUSPSão Paulo 05403-010SPBrazil Department of Radiology Sírio-Libanês HospitalSão Paulo 05652-900SPBrazil Department of Pathology School of Medical SciencesUniversity of Campinas-UNICAMPCampinas 13083-888São PauloBrazil Liver Transplant Unit Department of SurgerySchool of Medical SciencesUniversity of Campinas-UNICAMPCampinas 13083-888São PauloBrazil

BACKGROUND Challenging lesions,difficult to diagnose through non-invasive methods,constitute an important emotional burden for each patient regarding a still uncertain diagnosis(malignant x benign).In addition,from a therapeutic and prognostic point of view,delay in a definitive diagnosis can lead to worse *** of the main innovative trends currently is the use of molecular and functional methods to *** liver-specific contrast agents havebeen developed and studied in recent years to improve the performance of liver magnetic resonance imaging(MRI).More recently,one of the contrast agents introduced in clinical practice is gadoxetic acid(gadoxetate disodium).AIM To demonstrate the value of the hepatobiliary phases using gadoxetic acid in MRI for the characterization of focal liver lesions(FLL)in clinical *** Overall,302 Lesions were studied in 136 patients who underwent MRI exams using gadoxetic acid for the assessment of *** radiologists independently reviewed the MRI exams using four stages,and categorized them on a 6-point scale,from 0(lesion not detected)to 5(definitely malignant).The stages were:stage 1-images without contrast,stage 2-addition of dynamic phases after contrast(analogous to usual extracellular contrasts),stage 3-addition of hepatobiliary phase after 10 min(HBP 10’),stage 4-hepatobiliary phase after 20 min(HBP 20’)in addition to stage *** The interobserver agreement was high(weighted Kappa coefficient:0.81-1)at all stages in the characterization of benign and malignant *** diagnostic weighted accuracy(Az)was 0.80 in stage 1 and was increased to 0.90 in stage *** of the hepatobiliary phase increased Az to 0.98 in stage 3,which was also 0.98 in stage *** The hepatobiliary sequences improve diagnostic *** growing potential in the era of precision medicine,the improvement and dissemination of the method among medical specialties can bring benefits in the management of patients w

关键词： Liver Liver neoplasms Liver transplantation Medical oncology Diagnostic imaging Magnetic resonance imaging

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社会经济地位,而不是非洲血统的基因组,与血压相关:Bambui-Epigen(巴西)老龄化队列研究

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中华高血压杂志 2016年第2期24卷 109-109页

作者：刘莉叶鹏 Lima-costa mf Mello Mambrini JV Leite ML Peixoto SV Firmo JO Loyola Filho AI Gouveia MH Leal TP Pereira AC Macinko J Tarazona-Santos E

该研究旨在确定非洲基因组起源对巴西以社区为基础的多种族老年人群基线和11年血压变化的作用。方法：纳入随访11年的Bambui-Epigen（巴西）老龄化队列研究中的≥60岁受试者1272人的资料,观察指标为收缩压、舒张压和高血压控制率。潜在... 详细信息

该研究旨在确定非洲基因组起源对巴西以社区为基础的多种族老年人群基线和11年血压变化的作用。方法：纳入随访11年的Bambui-Epigen（巴西）老龄化队列研究中的≥60岁受试者1272人的资料,观察指标为收缩压、舒张压和高血压控制率。潜在的混杂因素包括人口学特征、社会经济地位（教育和家庭收入）、健康指标（吸烟、久坐的生活方式、高密度脂蛋白胆固醇、腰围、糖尿病和心血管病等）、抗高血压药物的使用。

关键词：社会经济地位血压变化队列研究基因组老龄化巴西非洲高密度脂蛋白胆固醇

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Resolutive Results with Oral Corticosteroids for Patients with COVID-19 in Pulmonary Inflammatory Phase. Successful Outpatient Experience during the Collapse of Belem Do Para Health System—Brazil

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Health 2021年第8期13卷 830-838页

作者： Roberto S. Zeballos Luciana N. L. Cruz Vânia C. R. Brilhante Adriana V. Lima Carlliane L. L. P. Martins Karla N. A. Lima Michele C. G. L. Leão Belinete L. Cruz Alessandra B. Dysarz Paulo C. B. Lobato Erika S. Almeida Rute A. P. costa Klevison C. Araújo Augusto C. C. Almeida Leônidas B. D. Junior Kathia O. Harada Rita H. V. S. Araújo elaine X. Prestes Ivete M. S. Souza Avany M. P. Pereira Antônio B. M. A. Rocha Iracema A. Estevão Fagnei I. C. Carvalho Paulo M. P. Melo Clinical Care Sao Paulo Brazil Instituto de Ciencias da Saude Faculdade de Medicina Universidade Federal do Para Belem Brazil Fundacao Publica Estadual Hospital de Clinicas Gaspar Vianna Belem Brazil Hospital da Policia Militar do Para Belem Brazil Imunoclinic Belem Brazil Universidade Estadual do Para Fundacao Santa Casa de Misericordia do Para Belem Brazil Clinica Barros Cirurgia Plastica Belem Brazil Secretaria de Estado de Saude Publica Castanhal Brazil Centro de Tratamento Oncologico Belem Brazil Sociedade Brasileira de Valorizaç ã o das Sociedades Medicas—SOBEMED S&#227 o Paulo Brazil Clinica de Nutrologia Sao Luiz Brazil Hospital Nipo Brasileiro de Olhos Belem Brazil Centro de Ciencias Biologicas e da Saude Universidade do Estado do Para Belem Brazil Hospital Regional do Baixo Amazonas Santarem Brazil Clinica Vallinoto Secretaria de Saude de Barcarena Barcarena Brazil Estrategia Saude da Familia Secretaria Municipal de Saude de Ananindeua Centro Universitario do Estado do Para Belem Brazil A. M. P. Endocrinologia Belem Brazil Instituto Avertano Rocha Belem Brazil Departamento de Neurocirurgia Hospital Militar de Area De Sao Paulo Sao Paulo Brazil

In the face of new diseases, medicine needs to reinvent itself in order to contain and control epidemics, such as the one we have recently faced, COVID-19, a disease with a wide spectrum of clinical severity. A new moment has been established, since the application of well-known, effective and safe medications for other diseases, has shown high success rates in the treatment of COVID-19. Thereunto, studies with early intervention are needed, which can change the unfavorable outcome of patients. In this article, we report the successful experience using an oral strategy during the collapse of Belem (Para, Brazil) Health System. Two hundred and ten patients were diagnosed with respiratory failure due to COVID-19, with no option of hospital treatment due to lack of beds and resources. These patients were then started on therapeutic regimen consisting of 40 mg prednisolone, 40 mg enoxaparin and macrolides (500 mg clarithromycin, 500 mg axetylcefuroxime) associated and followed in outpatient facilities. Two hundred and eight patients had an excellent therapeutic response and there were only two fatalities. These results push research boundaries, valuing outpatient treatment with early use of prednisolone in the initial pulmonary phase, preventing severe COVID-19 pneumonitis. Adoption of the proposed treatment intends to reduce the need for hospitalization, as well as lethality, with social robust benefits and incalculable economic savings since involves the use of accessible, safe and not expensive medications.

关键词： COVID-19 Corticosteroids Pulmonary Inflammatory Phase Collapse Brazil

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Punica granatum Leaf Lipophilic Fraction Favours Mortality by Attenuating Inflammation in Mice with Polymicrobial Sepsis

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Journal of Pharmacy and Pharmacology 2019年第7期7卷 355-367页

作者： Nagila Caroline Fialho Sousa Isabella Fernandes da Silva Figueiredo Mizael Calacio de Araujo elaine Pereira de Andrade Thais costa Alves Bruna Letícia Rosa da Silva Domingos Magno Santos Pereira Saulo JoseFigueiredo Mendes Joao Francisco Silva Rodrigues Jaqueline Pessoa Pontes Simone Aparecida Teixeira AndreAlvares Marques Vale Marcus Vinicius Dias-Souza Lidio Goncalves Lima-Neto Vera Lucia dos Santos Ana Paula Azevedo-Santos Marcelo Nicolas Muscara Valerio Monteiro-Neto Andrea de Souza Monteiro Luis Claudio Nascimento da Silva Elizabeth Soares Fernandes Programa de Pos-graduacao Universidade CEUMARua JosueMontellon°1RenascencaSao LuisMA 65075-120Brazil Departamento de Farmacologia Universidade de Sao PauloAv.Prof.Lineu Prestesn°1524Sala 326ButantanSao PauloSP 05508-900Brazil Programa de Pos-graduacao em Ciências em Saude Universidade Federal do MaranhaoAvenida dos Portuguesesn°1966BacangaSao LuisMA 65080-805Brazil Departamento de Microbiologia Universidade Federal de Minas GeraisAv.Antonio Carlosn°6627PampulhaBelo HorizonteMG 31270-901Brazil Departamento de Patologia Universidade Federal do MaranhaoAvenida dos Portuguesesn°1966BacangaSao LuísMA 65080-805Brazil

Punica granatum *** known antimicrobial and anti-inflammatory *** of different parts of this plant have been commonly used in the folk medicine to prevent and treat infections;and studies have supported the use of *** extracts for this ***,little is known of the effects of ***-derived fractions in severe infectious diseases such as ***,we investigated the actions of the hexane fraction(HF),rich in lipophilic compounds,obtained from the leaves of this plant,in a murine model of polymicrobial *** pre-treatment with HF increased mortality in septic *** same animals presented with lower levels of interleukin-6,nitric oxide and hydrogen peroxide in their peritoneal lavage samples than vehicle *** also increased polymorphonuclear cell accumulation in to the peritoneum of mice with ***-derived nitric oxide upon lipopolysaccharide stimuli was markedly reduced by incubation with ***,triterpenes,phytosterols,vitamin E and ascorbyl palmitate were detected in the *** results indicate that *** leaf lipophilic fractions may worsen sepsis *** effect may be associated with its bioactive compounds which act synergistically or not,increasing sepsis mortality in vivo.

关键词： P.granatum infection inflammation

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Trees as hotspots:Using forests,trees,and agroforestry to foster diverse sustainable landscapes

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Circular Agricultural Systems 2022年第1期2卷 30-37页

作者： Vincent Gitz Jianchu Xu Yuanchang Lu elaine Springgay Illias Animon Razan Khalifa Al Mubarak Robert Nasi Tony Simons Ranjit Barthakur Ren Wang Jianrong Su Fergus Sinclair Eduardo Somarriba Dossa G.O.Gbadamassi Ramni Jamnadass Christopher JKettle Dengpan Bu Anja Gassner Yves Laumonier Mi Zhou Himlal Baral Fangyuan Hua Peter AMinang Yufu Guo Michael Allen Brady Yanxia Li Peter Mortimer Bin Yang Heng Gui Fiona Worthy Deli Zhai Huafang Chen Huili Li Yufang Su Alexandre Meybeck Fabio Ricci CIFOR-ICRAF Bogor 16115Indonesia Center for Mountain Futures Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China CIFOR-ICRAF China Program World AgroforestryKunming 650201China State Key Laboratory of Animal Nutrition Institute of Animal SciencesChinese Academy of Agricultural SciencesBeijing 100081China Research Institute of Forest Resource Information Techniques Chinese Academy of ForestryBeijing 100091China Food and Agriculture Organization of the United Nations(FAO) Rome 00153Italy Food and Agriculture Organization of the United Nations(FAO) Bangkok 10200Thailand Mohamed bin Zayed Species Conservation Fund Abu Dhabi 131112United Arab Emirates Balipara Foundation GuwahatiAssam 781024India China National Gene Bank Shenzhen 518083China Research Institute of Resource Insects Chinese Academy of ForestryKunming 650233China World Agroforestry Centre(ICRAF) United Nations AvenueGigiriP.O.Box 30677-00100NairobiKenya CATIE Turrialba 30501Costa Rica Xishuangbanna Tropical Botanical Garden Chinese Academy of SciencesMengla 666303China Bioversity International Rome 00153Italy Global Landscapes Forum CIFOR gmbHCharles-de-Gaulle-Straße 553113 BonnGermany Institute of American and Oceania Study Chinese Academy of International Trade and Economic CooperationMinistry of CommerceBeijingChina Institute of Ecology Peking UniversityBeijing 100871China National Forestry and Grassland Administration Beijing 100714China International Network for Bamboo and Rattan(INBAR) Beijing 100102China Yunnan University Kunming 650500China Editorial Office of Biological Science Institute of BotanyChinese Academy SciencesBeijing 100093China

Forests,trees,and agroforestry(FTA)are ecosystem *** exemplify the contributions of biodiversity to sustainable and resilient landscapes,green circular economy and to sustainable agriculture and food systems for healthy ***,most research on these topics have been performed separately and lack *** International FTA-Kunming Conference'Forests,trees and agroforestry for diverse sustainable landscapes'22nd–24th June 2021,focused on these contributions,brought together scientists NGOs,and policy makers to further the understanding of tree diversity;provided a communication platform for scientists to share their research results;evaluated the role of tree diversity in agroecology and circular agriculture;assessed benefits of landscape restoration;and explored applied research in mountain ecosystems and food *** goals were to gather evidence that ground the design of solutions that can contribute to the implementation of the post 2020 Global Biodiversity Framework and towards the UN Food Systems Summit,and the overall implementation of the *** paper summarizes the outcomes of the international FTA Conference in Kunming 2021 and points out the highlights of research involved in six major themes.

关键词： landscape sustainable diverse

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