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On the Stability of Solutions of Nonlinear Functional Differential Equation of the Fifth-Order

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Advances in Pure Mathematics 2014年第8期4卷 357-367页

作者： A. M. A. Abou-El-ela A. I. Sadek A. M. Mahmoud R. O. A. Taie Department of Mathematics Faculty of Science Assiut University Assiut Egypt Department of Mathematics Faculty of Science New Valley Branch Assiut University New Valley El-Khargah Egypt

The main purpose of this paper is to investigate global asymptotic stability of the zero solution of the fifth-order nonlinear delay differential equation on the following form By constructing a Lyapunov functional, s... 详细信息

关键词： Global Asymptotic Stability Lyapunov Functional Fifth-Order Delay Differential Equations

树突状细胞在小鼠抗原诱发的关节炎滑膜组织和引流淋巴结中的快速集聚

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树突状细胞在小鼠抗原诱发的关节炎滑膜组织和引流淋巴结中的快速...

Isolation, cytotoxic activity and phylogenetic analysis of <i>Bacillus sp.</i>bacteria associated with the red sea sponge <i>Amphimedon ochracea</i>

中华医学会全国风湿病学年会

作者：张凤肖 Pauline Low ela Martin Ranjeny Thomas 河北省人民医院 Princess Alexandra Hospital University of QueenslandAustralia

目的:树突状细胞(DC)在类风湿关节炎(RA)的始发中起着重要作用,而用DC还集聚于RA滑膜组织,临床和动物实验都提示这些DC通过强大的致炎作用,特别是通过使滑膜组织转化成为淋巴样结构,来促成该疾病的持续。但是,DC在RA滑膜中的迁移特性还...

目的:树突状细胞(DC)在类风湿关节炎(RA)的始发中起着重要作用,而用DC还集聚于RA滑膜组织,临床和动物实验都提示这些DC通过强大的致炎作用,特别是通过使滑膜组织转化成为淋巴样结构,来促成该疾病的持续。但是,DC在RA滑膜中的迁移特性还不清楚。方法:将mBSA和完全福氏佐剂充分混合,皮下免疫C57／BL6小鼠,8天后在小鼠一侧膝关节内注射mBSA来诱发关节炎,另一侧关节内注射生理盐水作用对照,100％小鼠于注射mBSA后第5天出现关节炎症表现。为了探讨DC在关节炎滑膜内迁移变化的规律,我们应用流式细胞术动态观察了髓系DC(mDC)和淋巴系DC(pDC)在关节炎滑膜和引流淋巴结中的集聚变化。结果:在诱发关节炎第3天,关节炎侧引流淋巴结中CD45RA- CD11c+mDC和CD45RA+CD11c+pDC是对照侧的2倍。在第3天和第5天的关节炎滑膜中,中性粒细胞分别为89％和92％,mDC约占所有MHC-class Ⅱ+单个核细胞的30％,而未见到pDC。结论:抗原诱发的关节炎的发生与中性粒细胞和mDC在关节炎滑膜的集聚有关,mDC和pDC在引流淋巴结中的集聚先于和伴随着临床关节炎的症状出现。

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Advances in Bioscience and Biotechnology 2012年第7期3卷 815-823页

作者： Haiam M. Aboul-ela Mohamed A. Shreadah Nihad M. Abdel-Monem Galila A. Yakout Rob W. M. van Soest Department of Biochemistry Faculty of Science Alexandria University Alexandria Egypt Department of Marine Zoology Netherlands Centre for Biodiversity Leiden The Netherlands Marine Chemistry Laboratory the National Institute of Oceanography and Fisheries Alexandria Egypt

Most of marine sponges harbor dense and diverse microbial communities of bioactivity importance. Four Gram positive bacterial cultures (HA-21, HA-68, HA- MS-105 and HA-MS-119) were isolated from the sponge Amphimedon ochracea, collected from the Red Sea coast of Egypt. Bacterial species were identified based on the phylogenetic analysis of the nucleotide sequences of their 16S rDNA genes. The Sequences similarity values of 98% - 100% to other strains in the NCBI database showed strong similarities with the 16S rDNA genes of firmicutes (Bacillus sp.). The four bacterial species were submitted to the GenBank database and had accession numbers of: HA-21 [JQ-768238];HA-68 [JQ751264];HA-MS-105 [JQ768239];HAMS-119 [JQ768240]. The cytotoxic activities of the bacterial isolates were tested against three established human cancer cell lines;HepG2 (hepatocellular carcinoma), HCT (colon carcinoma) and MCF-7 (breast carcinoma). The inhibitory effect on these cell lines, measured by MTT cell assay protocol, revealed promising cytotoxic activity of the four isolates (IC50 values (μg/mL) were: HA-21: 13.2, 9.3 and 12.2;HA-68: 10.42, 4.3 and 5.5;HA-MS-105: 46.9, 28.6 and 21.3;HAMS-119: 10.42, 6.3 and 22.1;respectively). The recovery of bacterial strains with cytotoxic activity suggests that marine invertebrates remain a rich source for the isolation of culturable isolates capable of producing novel bioactive secondary metabolites.

关键词： Sponge Associated Bacteria Bacillus Sp. Bioactive Metabolites Cytotoxic Activity Phylogenetic Analysis

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术前放化疗对微创食管切除术的影响

中华胸心血管外科杂志 2013年第2期29卷 84-86,90页

作者：谢绚傅剑华张旭杨弘杨富罗孔嘉李小东 Amos ela BELIA 林婷华南肿瘤学国家重点试验室中山大学肿瘤防治中心胸科广州510060

目的探讨术前放化疗对微创食管切除术（MIE）手术质量及围术期的影响。方法符合入组条件的初治胸段局部晚期食管鳞癌63例，随机分成对照组与试验组，对照组33例行单纯MIE治疗，试验组30例行术前放化疗联合MIE治疗，遵循意向性处理原则... 详细信息

目的探讨术前放化疗对微创食管切除术（MIE）手术质量及围术期的影响。方法符合入组条件的初治胸段局部晚期食管鳞癌63例，随机分成对照组与试验组，对照组33例行单纯MIE治疗，试验组30例行术前放化疗联合MIE治疗，遵循意向性处理原则，对其手术质量及围术期状况进行对比评价。结果对照组与试验组中转开胸率分别是6．1％与3．3％；R0切除率分别是97．0％与93．3％；两组间差异均无统计学意义（P〉0．05）。试验组除胸部手术时间较对照组显著延长外（P=0．018），其余各项指标包括总手术时间、失血量、正常结构的暴露与保护、清扫淋巴结数目两组比较差异均无统计学意义（P〉0．05）。试验组总体并发症发生率50．0％，较对照组（39．4％）略高，但差异无统计学意义（P〉0．05）。结论术前放化疗虽略增加了MIE的手术难度，但对原发灶及淋巴结的根治性切除影响不大，围术期并发症增加不明显，因此术前放化疗后MIE安全可行。

关键词：食管肿瘤外科手术微创性食管切除术肿瘤辅助疗法

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普拉达基金会艺术中心意大利米兰

世界建筑导报 2022年第3期37卷 98-101页

作者： Iwan Baan(摄影) Bas Princen(摄影) Charlie Koolhaas(摄影) ela Bialkowska(摄影) Federico Pomignoli(摄影) OMA

普拉达基金会艺术中心新的总部位于米兰南部的Largo Isarco工业建筑园,前身是一座建于1910年的杜松子酒厂。改造后的建筑将拥有多样化的展览空间模式。除七栋包括仓库、实验室、酿造筒仓在内的保留建筑外,方案围绕中庭增加了三座新建筑... 详细信息

普拉达基金会艺术中心新的总部位于米兰南部的Largo Isarco工业建筑园,前身是一座建于1910年的杜松子酒厂。改造后的建筑将拥有多样化的展览空间模式。除七栋包括仓库、实验室、酿造筒仓在内的保留建筑外,方案围绕中庭增加了三座新建筑。这样的复合体建筑旨在为空间类型学项目表演扩展空间,充分展现该艺术类型的独特魅力。此次设计项目涉及七个已有建筑和三个新建筑。“讲台”,一个进行短期展示区域。“电影院”,一个多媒体礼堂。以及一个“塔楼”,一个高达九层,用来展示建校以来具有纪念意义的事物和举办的活动图像资料的永久性建筑。

关键词：永久性建筑展览空间意大利米兰筒仓杜松子酒中庭电影院图像资料

Supervised Learning Method: Critical Analysis and Updating of Cubing Rate Formulas for Determining Bark Masses of Prunus africana (Hook. f.) Kalkman (Rosaceae) in Cameroon

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Open Journal of Forestry 2024年第3期14卷 346-368页

作者： Armand Ndedy Bile Alain Mpouam Benoit Fouadjio Lorette Guedeu Kambale Muhesi Steve Tassiamba Paulette Kouam Eric Wete Marius ela Michèle Yimga Joseph Ambara Louis Aimé Fono Jean Lagarde Betti Department of Plant Biology Faculty of Science The University of Douala Douala Cameroon Department of Wood and Forest Sciences ISABEE University of Bertoua Bertoua Cameroon Department of Water and Forests Higher Institute of Agronomic Veterinary and Forestry Studies of Butembo Butembo Democratic Republic of Congo Department of Forestry Faculty of Agronomy and Agricultural Sciences University of Dschang Dschang Cameroon Department of Biology and Plant Faculty of Sciences University of Maroua Maroua Cameroon Deutsche Gresellschaft fur Internationale Zusammenarbeit GmbH (GIZ) Bertoua Cameroon Department of Mathematics and Computer Science Faculty of Science The University of Douala Douala Cameroon

The stem barks of Prunus africana are used in the treatment of the benign prostate. Cameroon is one of the important exporters of the barks. Despite the important measures adopted in Cameroon for sustaining its harvesting, some many chalenges still remain. The objective of this work is to refine the forest management parameters in relation to P. africana in the regions of Adamaoua and the South-West by developing a volume rate which makes it possible to estimate the production for a new stem. The work took place in two phases: in the South-West in 2010 and in Adamaoua in 2011. Data collection used the semi-direct method, while the cubing equation was deduced by the multiple linear regression method. Two models for volume estimation and three models for mass prediction were developed. The predictive parameters retained are diameter, height of the bole and thickness of the bark. Results show that the average mass of the dry bark for a given P. africana tree species is 27.55 ± 14.44 kg and this varies according to the site. The strong adjusted coefficient of determination (adjusted R2) observed illustrates the reliability of the proposed models. These models provide a reliable tool that can be adopted as a standard in Cameroon for P. africana.

关键词： Prunus africana Prostate Quota Mass Model Sustainable Management

Prevalence of Hepatitis C Virus and Associated Risk Factors among Inmates at New Bell Prison, Douala, Cameroon

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Open Journal of Epidemiology 2019年第2期9卷 119-128页

作者： Mathurin Pierre Kowo Firmin Ankouane Andoulo Larry Tangie Ngek Daniel Tchamdeu Sizimboue Antonin Ndjitoyap Ndam Buno ela Ondo Servais Eloumou Bagnaka Rocard Djanteng Elie-Claude Ndjitoyap Ndam Oudou Njoya Department on Internal Medicine and Specialities Faculty of Medicine and Biomedical Sciences University of Yaoundé I Yaoundé Cameroon Université des Montagnes Banganté Cameroon Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon Medical Center New Bell Prison Douala Cameroon

Although a high prevalence of HCV infection in correctional facilities has been well reported in several countries around the world, there has been no such data from Cameroon. The aim of this study was to determine the prevalence and factors associated with viral hepatitis C seropositivity among prisoners incarcerated at the New Bell Central Prison in Douala. From the 2nd to the 27th of July 2018, 940 inmates selected using a systematic random sampling method were interviewed to collect data on sociodemographic status, duration of incarceration, number of incarcerations and risk factors for HCV transmission. Blood samples were collected for screening of anti-HCV antibodies via HEPA-SCAN HCV CARD Test. Positive samples had a confirmatory ELISA test. Data were analysed using EPI DATA 4.***.0.0 software. Statistical significance was set at a p < 0.05. Of the 940 prisoners selected, 94.1% (884) were males. The mean age of the study population was 33.81 ± 10.35 years (extremes: 14 and 74 years). HCV prevalence was 4.4% (40). The use of non-injectable illicit drugs (OR 2.87 95% CI 1.44 - 5.73) (p = 0.002) but not injectable illicit drugs (OR 1.91 95% CI 0.43 - 8.41) (p = 0.42), male homosexuality (OR 17.45 95% CI 7.58 - 40.13) (p < 0.001), sharing of needles (OR 3.45 95% CI 1.59 - 7.83) (p = 0.001), past history of tattooing or piercing (OR 5.94 95% CI 2.80 - 12.16) (p < 0.001) and age ≥ 50 (OR 4.069;95% CI 1.9 - 8.68) (p = 0.003) were significantly associated with HCV antibodies positivity. Inmates in New Bell Central Prison accumulate risk factors for viral hepatitis C, thus contributing to the high prevalence in this setting. Control strategies and programs that reach this particular population should urgently be implemented.

关键词： Prevalence Risks factors Hepatitis C Prisoners

Assessing the Efficacy of Lemongrass (Cymbopogon citratus) and Sambong (Blumea balsamifera) Extracts in Combating Black Pod Disease: Sustainable Solutions for Controlling Phytophthora megakarya in Cameroon’s Cocoa Plantations

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American Journal of Plant Sciences 2024年第7期15卷 519-537页

作者： Gertrude Membang James Michel Tchotet Tchoumi Godswill Ntsomboh Ntsefong Emmanuel Yvan Mba ela Sylvere Landry Lontsi Dida Ludovic Tchuenkam Tsango Pascal Loïc Ekango Mbondjo Fritz Oben Tabi Innovative Plant Health Laboratory Faculty of Agronomy and Agricultural Sciences (FASA)-Bafia Annex University of Dschang Dschang Cameroon IDepartment of Plant Biology Faculty of Science University of Yaounde 1 Yaounde Cameroon Laboratory of Phytopathology and Crop Protection Faculty of Sciences University of Yaounde 1 Yaounde Cameroon Department of Soil Science Faculty of Agronomy and Agricultural Sciences (FASA) University of Dschang Dschang Cameroon

The use of plant extracts as antifungal agents is gaining increasing attention, particularly for the control of black pod disease in cocoa. Despite extensive research, current strategies haven’t been entirely effective. This study evaluated the effectiveness of Cymbopogon citratus and Blumea balsamifora leaf extracts, both individually and in combination, against Phytophthora megakarya. We assessed the efficacy of the most promising combination (75% B. balsamifera, 25% C. citratus) after storage at room temperature for up to 9 days. Agar microdilution and in vivo bioassays were conducted to determine antifungal susceptibility and effectiveness. Blumea extract exhibited the highest overall inhibitory activity, with the lowest minimum inhibitory concentration (117 µl mL−1) while C. citratus had a narrower range of MIC (146 to 233 µl mL−1). The combination of C. citratus and B. balsamifera demonstrated a synergistic effect against P. megakarya, achieving growth inhibition on V8 media (92.72 ± 4.20% to 100%) and on artificially infected detached pod cortex (92.24 ± 4.53% to 98.75 ± 1.25%), which was not significantly different from the positive control (Ridomil). Furthermore, this combination maintained its effectiveness for up to 9 days at room temperature. These findings suggest that combining plant extracts can enhance their antifungal properties.

关键词： Plant Extracts Antifungal Agents Synergistic Effect Black Pod Disease Cocoa

番茄潜叶蛾危害特征及14目防虫网的隔离效果

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西北农业学报 2022年第7期31卷 921-929页

作者：何云川毛植尧王田珍王树明马丽华普建文宁锦程普群周文武 Amr S.Abou El-ela 祝增荣海南浙江大学研究院海南三亚572025 浙江大学昆虫科学研究所浙江省作物病虫生物学重点实验室农业部作物病虫分子生物学重点实验室杭州310058 云南省玉溪市植保植检站云南玉溪653100 云南省峨山县植保植检站云南峨山653200 云南省峨山县小街镇农业农村综合服务中心云南峨山653201 国际生物防治组织茄科作物害虫生物防治国际工作组北京100193 亚历山大大学农学院植保系西宾库姆埃及21531

番茄潜叶蛾Tuta absoluta(Meyrick)是危害茄科作物的重大入侵农业害虫,明确番茄潜叶蛾的田间危害特征及防虫网对番茄潜叶蛾成虫的防控作用,为防虫网在温棚的使用提供技术指导。利用防虫网+性诱剂的方法,分析番茄潜叶蛾的田间治理效果。... 详细信息

番茄潜叶蛾Tuta absoluta(Meyrick)是危害茄科作物的重大入侵农业害虫,明确番茄潜叶蛾的田间危害特征及防虫网对番茄潜叶蛾成虫的防控作用,为防虫网在温棚的使用提供技术指导。利用防虫网+性诱剂的方法,分析番茄潜叶蛾的田间治理效果。采用田间观察和五点取样的方法,进行番茄潜叶蛾危害调查。在不同番茄品种的不同生育期监测到防虫网与对照处理的番茄潜叶蛾种群动态变化规律一致。苗期,‘德尔6’和‘粉帝F1’防虫网和对照处理的平均虫量分别为18.76、24.97只/板和75.92、87.71只/板(P>0.05);防虫网对两个品种的番茄潜叶蛾隔离率分别为39.10%和21.32%(P0.05);防虫网对两个品种的番茄潜叶蛾隔离率分别为22.95%和19.35%(P>0.05)。果期,‘德尔6’、‘鸿图’和‘粉帝F1’的防虫网和对照处理平均虫量分别为53.90、58.52只/板;47.52、65.79只/板和66.37、85.46只/板(P>0.05);防虫网对3个品种的番茄潜叶蛾隔离率分别为24.20%、28.93%和26.83%(P>0.05)。防虫网处理对3个生育期下的3个品种间的平均危害率均差异不显著(P>0.05),但防虫网处理的平均危害率均低于对照处理,差值达8.38%。二次多项式逐步回归分析结果表明番茄叶片或果实的平均危害率主要与潜叶蛾的早期虫口量相关。14目防虫网对番茄潜叶蛾具防控作用,隔离率最大为39.10%。

关键词：番茄潜叶蛾防虫网危害特征危害调查

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