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Effect of Chronic Administration of Cadmium on Anxiety-Like, Depression-Like and Memory Deficits in Male and Female Rats: Possible Involvement of Oxidative Stress Mechanism

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Journal of Behavioral and Brain Science 2018年第5期8卷 240-268页

作者： Mouloud Lamtai Jihane Chaibat Sihame Ouakki Inssaf Berkiks el-housseine rifi Aboubaker el Hessni Abdelhalem Mesfioui Ali Tadlaoui Hbibi Hassna Ahyayauch Azzouz Essamri Ali Ouichou Unit of Nervous and Endocrine Physiology Laboratory of Genetics Neuroendocrinology and Biotechnology Faculty of Science University Ibn Tofail Kenitra Morocco Laboratory of Synthesis Organic and Extraction Processes Department of Chemistry Faculty of Science University Ibn Tofail Kenitra Morocco Institut Supé rieur des Professions Infirmiè res et Techniques de Santé (ISPISTS) route Casablanca Rabat Morocco Laboratory of Agro-Resources and Process Engineering Faculty of Science University Ibn Tofail Kenitra Morocco

The main objective of this work is to study the effect of chronic administration of cadmium (Cd) on the level of depression-like, anxiety-like, memory state and oxidative stress in male and female Wistar rats. For this purpose, this study was conducted with 24 rats for each gender. Four groups were constituted: (Group 1: Control): received saline solution NaCl (0.9%), (Group 2: Cd-0.25;Group 3: Cd-0.5;Group 4: Cd-1): received daily 0.25 mg/kg, 0.5 mg/kg and 1 mg/kg of Cd respectively during 8 weeks. After treatment period, animals were tested in the open-field, elevated plus maze tests for anxiety-like behavior, and forced swimming test for depression-like behavior. The Y maze was used to evaluate the working memory and the Morris Water Maze, to evaluate space learning and spatial memory. The results revealed that in males, all doses of Cd provoke depression-like, while in females only the group treated with 1 mg/kg Cd shows elevated depression-like behavior. In regard to anxiety-like behavior, Cd induces an anxiogenic effect in both genders tests. In the Y-Maze test, both males and females expressed a low percentage of alternations, suggesting that working memory was affected by Cd at 1 mg/kg. In the Morris Water Maze test, the space learning and spatial memory were significantly impaired in the group Cd-1. Neurochemical analysis showed that levels of nitric oxide and lipid peroxidation in the hippocampus were significantly increased after Cd treatments. Overall analysis of our data revealed that Cd caused significant alterations in the examined parameters that were sex-dependent and dose-dependent.

关键词： Cadmium Depression-Like Anxiety-Like Memory Oxidative Stress

Comparison between seismic analysis of twisting and regular 52-story towers considering soil-structure interaction

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Earthquake Engineering and Engineering Vibration 2024年第3期23卷 663-675页

作者： Mohamed Naguib Abouelsaad Mohammed Shaaban Salah el Bagalaty Mohamed E.el Madawy Structural Engineering Department Faculty of EngineeringMansura UniversityMansoura 35511Egypt Faculty of Engineering Delta University for Science and TechnologyGamasa 35712Egypt

A dynamic analysis of both twisting and regular towers is carried out to determine the results of considering soil-structure interaction(SSI)on high-rise *** addition,the difference between the seismic performance of using twisting towers over regular ones is *** twisting tower is a simulation of the Evolution Tower(Moscow).The towers’skeletons consist of RC elements and rest on a reinforced concrete piled-raft *** soil model is considered as multi-layered with the same soil properties as the zone chosen for the analysis(New Mansoura City,Egypt).The only difference between both towers is their shape in *** whole system is modelled and analyzed in a single step as one full 3D model,which is known as the direct approach in *** analyses are carried out using finite-element software(Midas GTS NX).Dynamic output responses due to three records of seismic loads are proposed and presented in some *** on the results,it is concluded that SSI has a considerable effect on the dynamic response of tall buildings mainly because of the foundation flexibility,as it leads to lengthening the vibration period,increasing the story drift and the base shear for both cases.

关键词： soil-structure interaction seismic analysis twisting towers base shear story drift finite element method Midas GTS NX

Gender-Based Analysis of User Reactions to Facebook Posts

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Big Data Mining and Analytics 2024年第1期7卷 75-86页

作者： Yassine el Moudene Jaafar Idrais Rida el Abassi Abderrahim Sabour Mathematical Engineering and Computer Science Laboratory Faculty of SciencesIbn Zohr UniversityAgadir 8706Morocco Department of Computer Science Mathematical−High School of Technology Ibn Zohr UniversityAgadir 8706Morocco

Online Social Networks(OSNs)are based on the sharing of different types of information and on various interactions(comments,reactions,and sharing).One of these important actions is the emotional reaction to the *** diversity of reaction types available on Facebook(namely FB)enables users to express their feelings,and its traceability creates and enriches the users’emotional identity in the virtual *** paper is based on the analysis of 119875012 FB reactions(Like,Love,Haha,Wow,Sad,Angry,Thankful,and Pride)made at multiple levels(publications,comments,and sub-comments)to study and classify the users’emotional behavior,visualize the distribution of different types of reactions,and analyze the gender impact on emotion *** of these can be achieved by addressing these research questions:who reacts the most?Which emotion is the most expressed?

关键词： profiling knowledge extraction data mining emotion mining social media data crawling Facebook reactions gender

Stability analysis of a time-delayed Van der Pol–Helmholtz–Duffing oscillator in fractal space with a non-perturbative approach

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Communications in Theoretical Physics 2024年第4期76卷 22-31页

作者： Yusry O el-Dib Department of Mathematics Faculty of EducationAin Shams UniversityRoxyCairoEgypt

The time-delayed fractal Van der Pol–Helmholtz–Duffing(VPHD)oscillator is the subject of this paper,which explores its mechanisms and highlights its stability *** time-delayed technologies are currently garnering significant attention,the focus of this research remains crucially relevant.A non-perturbative approach is employed to refine and set the stage for the system under *** innovative methodologies introduced yield an equivalent linear differential equation,mirroring the inherent nonlinearities of the ***,the incorporation of quadratic nonlinearity into the frequency formula represents a cutting-edge *** analytical solution's validity is corroborated using a numerical *** conditions are ascertained through the residual Galerkin ***,it is observed that the delay parameter,in the context of the fractal system,reverses its stabilizing influence,impacting both the amplitude of delayed velocity and the *** analytical solution's precision is underscored by its close alignment with numerical ***,the study reveals that fractal characteristics emulate damping *** its applicability across diverse nonlinear dynamical systems,this non-perturbative approach emerges as a promising avenue for future research.

关键词： Van der Pol-Helmholtz-Duffing oscillator fractal space time-delay non-perturbative approach stability analysis el-Dib's frequency formula

Nonlinear wave dispersion in monoatomic chains with lumped and distributed masses:discrete and continuum models

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Applied Mathematics and Mechanics(English Edition) 2024年第4期45卷 633-648页

作者： E.GHAVANLOO S.el-BORGI School of Mechanical Engineering Shiraz UniversityShiraz 71963-16548Iran Mechanical Engineering Program Texas A&M University at QatarDoha 23874Qatar

The main objective of this paper is to investigate the influence of inertia of nonlinear springs on the dispersion behavior of discrete monoatomic chains with lumped and distributed *** developed model can represent the wave propagation problem in a non-homogeneous material consisting of heavy inclusions embedded in a *** inclusions are idealized by lumped masses,and the matrix between adjacent inclusions is modeled by a nonlinear spring with distributed ***,the model is capable of depicting the wave propagation in bi-material bars,wherein the first material is represented by a rigid particle and the second one is represented by a nonlinear spring with distributed *** discrete model of the nonlinear monoatomic chain with lumped and distributed masses is first considered,and a closed-form expression of the dispersion relation is obtained by the second-order Lindstedt-Poincare method(LPM).Next,a continuum model for the nonlinear monoatomic chain is derived directly from its discrete lattice model by a suitable continualization *** subsequent use of the second-order method of multiple scales(MMS)facilitates the derivation of the corresponding nonlinear dispersion relation in a closed *** novelties of the present study consist of(i)considering the inertia of nonlinear springs on the dispersion behavior of the discrete mass-spring chains;(ii)developing the second-order LPM for the wave propagation in the discrete chains;and(iii)deriving a continuum model for the nonlinear monoatomic chains with lumped and distributed ***,a parametric study is conducted to examine the effects of the design parameters and the distributed spring mass on the nonlinear dispersion relations and phase velocities obtained from both the discrete and continuum *** parameters include the ratio of the spring mass to the lumped mass,the nonlinear stiffness coefficient of the spring,and the wave amplitude.

关键词： nonlinear mass-spring chain discrete model continuum model LindstedtPoincare method(LPM) method of multiple scales(MMS) dispersion phase velocity

Modeling environmental sensitivity and risk assessment of PAHs in sediments along two marine coastal areas in Egypt

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Petroleum Research 2024年第1期9卷 125-142页

作者： Muhammad A.el-Alfy National Institute of Oceanography and Fisheries NIOFCairoEgypt

Modeling the environmental sensitivity index(ESI)is vital in the planning and management processes,especially along the coastal *** main objectives of the study were to define the main sources of polycyclic aromatic hydrocarbons(PAHs),establish an ESI model,and measure the risk of PAHs on humans and the environment using various *** methodology of the research involved analyzing PAHs according to the EPA 550 methodology in sediments of the coastline in two important coastline areas in Egypt,namely the Gulf of Suez and the Mediterranean Sea,modeling the sensitivity of PAHs using ArcGIS 10.5 by integrating different physical,biological,and land use/cover factors,identifying the sources,and performing a risk *** sediment samples were collected from each *** produced sensitivity map could explain the highly sensitive areas along the Mediterranean Sea and Gulf of Suez coastlines(especially areas that were near drains'outlets,industrial sites,and sea ports).The highest mean PAH concentrations were Acenaphthylene and Fluorine in the Mediterranean Sea and Suez Gulf,***'s obvious that the individual PAH concentrations were within the ERL,ERM,and Pel threshold limits,indicating no adverse biological *** ratios of BaA/BaA+Chy,Flu/Flu+Py,and Ant/Ant+Phe gave an indication that most PAH sources were petrogenic(63.64%)and others(36.36%)were from petroleum *** principle component analysis(PCA)indicated a diverse correlation among the isomer ratios and LU/LC *** carcinogenic risk values were in the very low category(elines and seawater free of oil spillage act

关键词： Polycyclic aromatic hydrocarbons(PAHs) Modeling Sensitivity Gulf of Suez And Mediterranean sea

Detection of internal crack growth in polyethylene pipe using guided wave ultrasonic testing

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Earthquake Engineering and Engineering Vibration 2024年第2期23卷 319-329页

作者： Jay Kumar Shah Hao Wang Said el-Hawwat Centre of Advanced Infrastructure and Transportation RutgersThe State University of New JerseyNJ 08854USA Department of Civil and Environmental Engineering RutgersThe State University of New JerseyNJ 08854USA

Despite the success of guided wave ultrasonic inspection for internal defect detection in steel pipes,its application on polyethylene(PE)pipe remains relatively *** growth of internal cracks in PE pipe severely affects its pressure-holding capacity,hence the early detection of internal cracks is crucial for effective pipeline maintenance *** study extends the scope of guided wave-based ultrasonic testing to detect the growth of internal cracks in a natural gas distribution PE *** experiments and a finite element model were planned to study the wave-crack interaction at different stages of axially oriented internal crack growth with a piezoceramic transducer-based setup arranged in a pitch-catch *** dispersion analysis supplemented with preliminary experiments was performed to isolate the optimal inspection frequency,leading to the selection of the T(0,1)mode at 50-kHz for the investigation.A transmission index based on the energy of the T(0,1)mode was developed to trace the extent of simulated crack *** findings revealed an inverse linear correlation between the transmission index and the crack depth for crack growth beyond 20%crack depth.

关键词： polyethylene pipes internal cracks guided wave ultrasonic testing torsional modes finite element modeling

Existence and numerical approximation of a solution to frictional contact problem for electro-elastic materials

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Applied Mathematics(A Journal of Chinese Universities) 2024年第2期39卷 201-219页

作者： Othman Baiz el-Hassan Benkhira Rachid Fakhar University Ibn Zohr Lab.ESERFP of OuarzazateMorocco University Moulay Ismail Faculty of SciencesLaboratory MACSESTMBP 3103Toulal-MeknesMorocco University Sultan Moulay Slimane Laboratory LS2MEPolydisciplary Faculty of Khouribga25000 KhouribgaMorocco

In this paper,a frictional contact problem between an electro-elastic body and an electrically conductive foundation is *** contact is modeled by normal compliance with finite penetration and a version of Coulomb’s law of dry friction in which the coefficient of friction depends on the *** addition,the effects of the electrical conductivity of the foundation are taken into *** model leads to a coupled system of the quasi-variational inequality of the elliptic type for the displacement and the nonlinear variational equation for the electric *** existence of a weak solution is proved by using an abstract result for elliptic variational inequalities and a fixed point ***,a finite element approximation of the problem is *** some regularity conditions,an optimal order error estimate of the approximate solution is ***,a successive iteration technique is used to solve the problem numerically and a convergence result is established.

关键词： piezoelectric material frictional contact variational Inequality fixed point process finite element method error estimation iteration method

A review on the multi-scaled structures and mechanical/thermal properties of tool steels fabricated by laser powder bed fusion additive manufacturing

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International Journal of Minerals,Metallurgy and Materials 2024年第5期31卷 1048-1071页

作者： Huajing Zong Nan Kang Zehao Qin Mohamed el Mansori Arts et Metiers Institute of Technology MSMPHESAM UniversitéChâlons-en-Champagne F-51006France Texas A&M Engineering Experiment Station Institute for Manufacturing SystemsCollege Station TX77843USA

The laser powder bed fusion(LPBF) process can integrally form geometrically complex and high-performance metallic parts that have attracted much interest,especially in the molds *** appearance of the LPBF makes it possible to design and produce complex conformal cooling channel systems in ***,LPBF-processed tool steels have attracted more and more *** complex thermal history in the LPBF process makes the microstructural characteristics and properties different from those of conventional manufactured tool *** paper provides an overview of LPBF-processed tool steels by describing the physical phenomena,the microstructural characteristics,and the mechanical/thermal properties,including tensile properties,wear resistance,and thermal *** microstructural characteristics are presented through a multiscale perspective,ranging from densification,meso-structure,microstructure,substructure in grains,to ***,a summary of tool steels and their challenges and outlooks are introduced.

关键词： additive manufacturing laser powder bed fusion tool steel multi-scaled structure mechanical properties thermal properties