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Journal of Geriatric Cardiology 2017年第9期14卷 590-592页

作者： Karapet v Davtyan Andrey A Kalemberg Arpi H Topchyan Georgiy Y Simonyan ekaterina v bazaeva victoria S Shatahtsyan Laboratory for Interventional Arrhythmia Treatment of “National Medical Research Center for Preventive Medicine” Ministry of Healthcare of the RussianFederation Petroverigskiy lane Moscow Russia

Atrial fibrillation （AF） is the most common cardiac ar-rhythmia in clinical practice with an increasing incidenceand prevalence. With ageing, the risk of thromboembolicand hemorrhagic events increases dramatically. As it hasbeen reported previously, 3-year survival rate among pa-tients with AF over 75 years of age after stroke is less than50%, and almost 90% of those patients will remain dis-abled.

关键词： Left atrial appendage closure Oral anticoagulation therapy Stroke prevention The elderly

Morphology of crater and caldera lakes in the Far Eastern region of Russia and the features of their development

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Journal of Mountain Science 2024年第4期21卷 1246-1258页

作者： Dmitrii N.KOZLOv ekaterina v.LEBEDEvA Institute of Marine Geology and Geophysics Far Eastern Branch of the Russian Academy of SciencesYuzhno-Sakhalinsk 693022Russia Institute of Geography Russian Academy of SciencesMoscow 119017Russia

volcanic lakes in the Kuril-Kamchatka region are difficult to access,and for this reason,they remain poorly studied,with only scattered and brief data *** authors have conducted a study of 10 lake basins using modern digital echolocation survey techniques and have also compiled and summarized published data for 15 lakes in the region,calculating their main morphometric *** has been established that many caldera lake basins are modified by young explosive funnels,extrusive or effusive domes,and exhibit traces of hydrothermal *** lakes of the same genetic type in the Kuril-Kamchatka region are similar in depth and depression forms,the group of caldera lakes shows less homogeneity across all morphometric *** was found that the absolute heights of the reservoirs on Kamchatka Peninsula are generally greater than those on the Kuril Islands,as is often the case with the size of their *** volcanic lakes under study can rapidly change their volume and shape under the influence of endogenous *** the first time for this region,on the base of repeated observations,underwater extrusive dome rate growth and the approximate rates of 2 lake level changes were *** observations of lakes in the Ksudach calderas(Kamchatka)and on Simushir Island indicate approximate rates of level changes:a decrease ranging within 0.5-0.6 m per year(over a 27-year observation interval)and an increase reaching up to 0.26 m per year(over a 48-year interval).The growth rate of the underwater extrusive dome in Lake Shtyubel has averaged 1-1.6 m per year over the past 25 *** analysis has facilitated the first generalization regarding the morphology and developmental features of crater and caldera lakes in the Kuril-Kamchatka region of Russia,representing an important step in their *** results obtained will provide a solid foundation for subsequent research in this region and may be of interest to researchers studying

关键词： volcanic lakes Echolocation survey volcanism Gashydrotherms Kamchatka Kuril Islands

Structural traits of woody plants and geomorphological conditions to the vegetation recovery at Ksudach caldera(Southern Kamchatka) since the explosive eruption in 1907

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Journal of Mountain Science 2020年第7期17卷 1613-1635页

作者： KOPANINA Anna v LEBEDEvA ekaterina v vLASOvA Inna I TALSKIKH Anastasia v Institute of Marine Geology and Geophysics Far Eastern Branch of the Russian Academy of SciencesNauka street1 B693022Yuzhno-SakhalinskRussia Institute of Geography Russian Academy of SciencesStaromonetny s-str.29119017MoscowRussia

This study considers the restoration of the plant cover destroyed by a catastrophic volcano eruption in the south of Kamchatka Peninsula(the Ksudach caldera,Shtyubel cone),with a particular attention to the role of woody *** aims to qualitatively estimate(at a qualitative level)the rate of the primary succession development depending on the microrelief and the modern relief-forming *** vegetation recovery in the caldera after the Shtyubel cone eruption 109 years ago proceeds slowly and *** proceeds most slowly on a thick tephra mantle continuously disturbed by water and wind erosion,lahars,debris flows,landslides,*** conditions are most typical of the western part of the caldera dominated by pumice fields with occasional patches of pioneer herbs and dwarf *** tundra communities with gradually expanding patches of shrub alder develop in the southern,eastern and northeastern parts of the Ksudach *** 1997 the area of the shrub alder communities has increased by 1.9 times,while the alpine tundra–by 1.3 times *** woody plants(dwarf shrubs and prostrate shrubs)are of particular importance in the process of the vegetation recovery on pumice *** suggest that the bark thickness of woody plants is an integrated indicator,which may serve for estimating the state of ecosystem in the course of the primary succession development on juvenile *** extremely inhospitable environments cause changes in physiological processes in the plant body and in its bark in *** results show that woody plants have a"thin"bark and develop some structural-functional arrangements for keeping bark tissues at their ***,the woody plant structure and the rate of changes in plant communities are under control of the geomorphic conditions and primarily–of physicochemical features of the pyroclastic cover.

关键词： Ksudach caldera Pioneer species Woody plants Bark Pyroclastic deposits Geomorphological processes

Advances in small animal mesentery models for in vivo flow cytometry,dynamic microscopy,and drug screening

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World Journal of Gastroenterology 2007年第2期13卷 192-218页

作者： ekaterina I Galanzha valery v Tuchin vladimir P Zharov Philips Classic Laser Laboratories University of Arkansas for Medical Sciences (UAMS) Little Rock AR United States Department of Optics and Biomedical Physics Research-Educational Institute of Optics and Biophotonics Saratov State University Saratov Russia Department of Optics and Biomedical Physics Research-Educational Institute of Optics and Biophotonics Saratov State University Saratov Russia Philips Classic Laser Laboratories University of Arkansas for Medical Sciences (UAMS) Little Rock AR United States

Using animal mesentery with intravital optical microscopy is a well-established experimental model for studying blood and lymph microcirculation in vivo. Recent advances in cell biology and optical techniques provide the basis for extending this model for new applications, which should generate significantly improved experimental data. This review summarizes the achievements in this specific area, including in vivo label-free blood and lymph photothermal flow cytometry, super-sensitive fluorescence image cytometry, light scattering and speckle flow cytometry, microvessel dynamic microscopy, infrared (IR) angiography, and high-speed imaging of individual cells in fast flow. The capabilities of these techniques, using the rat mesentery model, were demonstrated in various studies; e.g., real-time quantitative detection of circulating and migrating individual blood and cancer cells, studies on vascular dynamics with a focus on lymphatics under normal conditions and under different interventions (e.g. lasers, drugs, nicotine), assessment of lymphatic disturbances from experimental lymphedema, monitoring cell traffic between blood and lymph systems, and high-speed imaging of cell transient deformability in flow. In particular, the obtained results demonstrated that individual cell transportation in living organisms depends on cell type (e.g., normal blood or leukemic cells), the cell’s functional state (e.g., live, apoptotic, or necrotic), and the functional status of the organism. Possible future applications, including in vivo early diagnosis and prevention of disease, monitoring immune response and apoptosis, chemo- and radio-sensitivity tests, and drug screening, are also discussed.

关键词： Lymph microcirculation Transmission digital microscopy Rat mesentery Flow cytometry Photothermal technique

Age of maturation and behavioral tactics in male yellow ground squirrel Spermophilus fulvus during mating season

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Current Zoology 2014年第6期60卷 700-711页

作者： Nina A. vASILIEvA ekaterina v. PAvLOvA Sergey v. NAIDENKO Andrey v.TCHABOvSKY A.N. Severtsov Institute of Ecology and Evolution Russian Academy of Sciences 33 Leninsky pr. Moscow 119071 Russia

Life-history theory predicts that in hibemators age of maturation is related positively to body size and negatively to the duration of active season aboveground. Yellow souslik is a large-sized ground squirrel with long hibernation, which suggests late maturation. We used four-year field observations of marked individuals to determine the age of maturation in males through analysis of age-dependent variation in body size, mass, androgen status, timing of spring emergence, ranging patterns and social behavior during the mating season. Yearling males were smaller, lighter, had lower level of fecal testosterone, emerged later and had smaller home ranges than older males. Social activity and the number of females encountered did not differ between age classes. After the second hibernation none of the studied parameters varied with age. Cluster analysis revealed two behavioral tactics：＂active＂ males （adults only） emerged earlier, ranged more widely, initiated more contacts, encountered more females and were heavier than ＂passive＂ males （both yearling and adult）. Thus, males of S. fulvus reached adult size and matured after two hibernations, which is relatively fast for such a big species with short active period. Indirect evidence for copulations and high variation among yearlings in all parameters suggest that some of them might successfully compete with adults. Active tactic of wandering and searching for females is energetically costly, and probably only adult males in good physical condition can afford it, whereas passive tactic of residing is energy saving and good for adults in poor condition and for yearlings that are continuing to grow.

关键词： Age of maturation Mating system Reproductive tactics Ground squirrel Spermophilusfulvus

Numerical 3D-modeling of spall and shear fractures in shells of austenitic 12Kh18N10T steel and 30KhGSA steel under their spherical and quasi-spherical explosive loading

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International Journal of Modeling, Simulation, and Scientific Computing 2015年第1期6卷 173-211页

作者： Evgeny A.Kozlov Oleg v.Ol’khov ekaterina v.Shuvalova Russian Federal Nuclear Center–Zababakhin Research Institute of Technical Physics Snezhinsk Russia Russian Federal Nuclear Center–Research Institute of Experimental Physics Sarov Russia

To pursue vNIIEF–vNIITF joint investigations,this paper briefly describes the experimental setup and provides numerical 3D-computation results(LEGAK-3D technique)on special features in the convergence dynamics of steel shells under their quasi-spherical explosive loading in the system with the 40-mm outer radius of the explosive *** computation results were compared with the data experimentally registered for shells of the 30KhGSA steel,both as-received and quenched to HRC 35...40,and the austenitic 12Kh18N10T stainless *** comparison was also made with laserinterferometry results obtained directly under explosive loading,as well as with gammatomography and scanning electron microscopy investigations of the recovered shells.

关键词： Convergence dynamics of shell spall and shear damages explosive loading

Selection of shaped charges parameters for producing aluminum particles with velocities in the range of 2.5-16 km/s

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Defence Technology（防务技术） 2024年第8期38卷 126-135页

作者： vladimir I.Kolpakov Sergey v.Fedorov ekaterina P.vinogradova Irina A.Bolotina Bauman Moscow State Technical University Moscow 105005Russia

Testing rocket and space technology objects in ground conditions for resistance to the impact of meteoroids and fragments of space debris can be carried out using shaped charges. To substantiate the design parameters of shaped charges that ensure the formation of aluminum particles in a wide velocity range(from 2.5 to 16 km/s), numerical modeling of the formation process was carried out within the framework of a two-dimensional axisymmetric problem of continuum mechanics using three different computing codes to increase the reliability of the results. The calculations consider shaped charges with a diameter of 20-100 mm with aluminum liners of various shapes. It is shown that the formation of particles with velocities close to the lower limit of the considered range is ensured by gently sloping segmental liners of degressive thickness. To form higher-velocity particles with velocities over 5 km/s, it is proposed to use combined liners, the jet-forming part of which has the shape of a hemisphere of constant thickness or the shape of a semi-ellipsoid or semi-superellipsoid of rotation of degressive thickness.

关键词： Space debris Meteoric impact Explosion Shaped charge High-velocity aluminum element Segmental liner Combined liner Numerical simulation

Photoluminescence,structural and antibacterial properties of co-dopedβ-Ca_(3)(PO_(4))_(2)-type phosphates Ca_(8)CuRE(PO_(4))_(7)(RE=Eu-Er)

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Journal of Rare Earths 2024年第9期42卷 1658-1668,I0002页

作者： Ivan v.Nikiforov ekaterina v.Iliin Bogdan I.Lazoryak Sergey M.Aksenov Pavel v.Slukin Dina v.Deyneko Department of Chemistry Lomonosov Moscow State University119991MoscowRussia Laboratory of Arctic Mineralogy and Material Sciences Kola Science CentreRussian Academy of Sciences184209ApatityRussia Geological Institute Kola Science CentreRussian Academy of Sciences184209ApatityRussia State Scientific Center of Applied Microbiology and Biotechnology of Rospotrebnadzor 24 Block A142279ObolenskRussia

Novel Ca_(8)CuRE(PO_(4))_(7)where RE^(3+)=Eu^(3+),Tb^(3+),Dy^(3+),Ho^(3+)and Er^(3+)were synthesized by a solid-state method in *** structures of the samples were characterized by powder X-ray diffraction using Rietveld refinement to determine the occupation of crystal *** samples are found to have a centrosymmetric structure with space group R3c,as shown by dielectric *** synthesized Ca_(8)CuRE(PO_(4))_(7)samples have multifunctional *** Cu^(2+)ions provide antibacterial properties,while the rare earth elements ions exhibit luminescence properties,and theβ-Ca_3(PO_(4))_(2)-type host is *** photoluminescence properties of RE^(3+)ions were studied and compared with other simmilar Ca_(8)MRE(PO_(4))_(7)phosphates,where M is a divalent *** photoluminescence intensity quenching in terms of energy transfer from RE^(3+)to Cu^(2+)is *** bioactive properties were studied in relation to antibacterial activity against *** and *** syntesized Ca_(8)CuRE(PO_(4))_(7)samples demonstrate very high and stable inhibition of bacteria *** correlation between crystal structure and properties is *** combining multiple approaches to the directio nal design of such materials,several important properties within a single chemical compound to achieve biovisualization and bioactive properties simultaneously can be combined.

关键词： β-Ca_(3)(PO_(4))_(2) Whitlockite-type structure Bioactive phosphates TCP Photoluminescence Rare earths

Neurohumoral,cardiac and inflammatory markers in the evaluation of heart failure severity and progression

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Journal of Geriatric Cardiology 2021年第1期18卷 47-66页

作者： ekaterina A Polyakova Evgeny N Mikhaylov Dmitry L Sonin Yuri v Cheburkin Mikhail M Galagudza Almazov National Medical Research Centre Saint-PetersburgRussia

Heart failure is common in adult population,accounting for substantial morbidity and mortality *** main risk factors for heart failure are coronary artery disease,hypertension,obesity,diabetes mellitus,chronic pulmonary diseases,family history of cardiovascular diseases,cardiotoxic *** main factor associated with poor outcome of these patients is constant progression of heart *** the current review we present evidence on the role of established and candidate neurohumoral biomarkers for heart failure progression management and diagnostics.A growing number of biomarkers have been proposed as potentially useful in heart failure patients,but not one of them still resembles the characteristics of the"ideal biomarker."A single marker will hardly perform well for screening,diagnostic,prognostic,and therapeutic management ***,the pathophysiological and clinical significance of biomarkers may depend on the presentation,stage,and severity of the *** authors cover main classification of heart failure phenotypes,based on the measurement of left ventricular ejection fraction,including heart failure with preserved ejection fraction,heart failure with reduced ejection fraction,and the recently proposed category heart failure with mid-range ejection *** could envisage specific sets of biomarker with different performances in heart failure progression with different left ventricular ejection fraction especially as concerns prediction of the future course of the disease and of left ventricular adverse/reverse *** article is intended to provide an overview of basic and additional mechanisms of heart failure progression will contribute to a more comprehensive knowledge of the disease pathogenesis.

关键词： cardiac and inflammatory markers in the evaluation of heart failure severity and progression Neurohumoral

Photocatalytic Treatment of Waste Water from Rice Husk Alkaline Hydrolysate

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Rice science 2019年第4期26卷 257-260页

作者： Olga D. AREFIEvA Marina S. vASILYEvA ekaterina v. ERMOLENKO Anastasiia v. BYCHKOvA Far Eastern Federal University Vladivostok 690950Russian Federation Institute of Chemistry Far-Eastern BranchRussian Academy of Sciences Vladivostok 690022 Russian Federation National Scientific Center of Marine Biology Far Eastern BranchRussian Academy of SciencesVladivostok 690041Russian Federation

We carried out photocatalytic treatment of a lignin-free solution of rice husk alkaline hydrolysate [pH of 2, chemical oxygen demand（COD） of 12.8 g/L] using photo-Fenton process in the ultraviolet（Uv, wavelength of 365 nm） and visible spectrum. Oxidation of lignin was performed at a constant mass ratio of COD:H2O2 as 1:2 and Fe2+ concentration of 80 mg/L. It was established that for the destruction of alkaline lignin, exposure to visible or Uv radiation was necessary. Decolorization efficiency of a lignin-free solution depends on the dilution rate of the solution. The advanced oxidative photo-Fenton process(Uv/Н2О2/Fe2+) made it possible to reduce the color of lignin-free solution at a dilution ratio of 1:5 by 94% of decolorization efficiency, 87% of phenolic compound and 79% of COD. With the help of gas chromatography, the products of lignin destruction were low-toxic and usable.

关键词： chemical oxygen demand dilution ratio visible spectrum