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mineralized collagen scaffolds fabricated with amniotic membrane matrix increase osteogenesis under inflammatory conditions

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Regenerative Biomaterials 2020年第3期7卷 247-258页

作者： marley J.Dewey eileen m.johnson Simona T.Slater Derek J.milner matthew B.Wheeler Brendan A.C.Harley Department of materials Science and Engineering University of Illinois at Urbana-Champaign110 Roger Adams Laboratory600 S.Mathews Ave.UrbanaIL 61801USA Department of Bioengineering University of Illinois at Urbana-Champaign110 Roger Adams Laboratory600 S.Mathews Ave.UrbanaIL 61801USA Department of Chemical and Biomolecular Engineering University of Illinois at Urbana-Champaign110 Roger Adams Laboratory600 S.Mathews Ave.UrbanaIL 61801USA Carl R.Woese Institute for Genomic Biology University of Illinois at Urbana-Champaign110 Roger Adams Laboratory600 S.Mathews Ave.UrbanaIL 61801USA Department of Animal Sciences University of Illinois at Urbana-Champaign110 Roger Adams Laboratory600 S.Mathews Ave.UrbanaIL 61801USA

Defects in craniofacial bones occur congenitally,after high-energy impacts,and during the course of treatment for stroke and *** injuries are difficult to heal due to the overwhelming size of the injury area and the inflammatory environment surrounding the *** inflammatory response after injury may greatly inhibit regenerative *** have developed mineralized collagen scaffolds that can induce osteogenic differentiation and matrix biosynthesis in the absence of osteogenic media or supplemental *** amniotic membrane is derived from placentas and has been recently investigated as an extracellular matrix to prevent chronic ***,we hypothesized that a mineralized collagen-amnion composite scaffold could increase osteogenic activity in the presence of inflammatory *** report mechanical properties of a mineralized collagen-amnion scaffold and investigated osteogenic differentiation and mineral deposition of porcine adipose-derived stem cells within these scaffolds as a function of inflammatory *** of amniotic membrane matrix promotes osteogenesis similarly to un-modified mineralized collagen scaffolds,and increases in mineralized collagen-amnion scaffolds under inflammatory ***,these findings suggest that a mineralized collagen-amnion scaffold may provide a beneficial environment to aid craniomaxillofacial bone repair,especially in the course of defects presenting significant inflammatory complications.

关键词： mineralized collagen scaffolds amniotic membrane inflammation stem cell osteogenesis

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Testing the potential mechanisms for the maintenance of a genetic color polymorphism in bluefin killifish populations

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Current Zoology 2018年第6期64卷 733-743页

作者： Ashley m.johnson Chia-Hao CHANG Rebecca C.FULLER Department of Animal Biology School of Integrative BiologyUniversity of Illinois at Urbana-ChampaignChampaignIL 61820USA

The maintenance of genetic variation in the face of natural selection is a long-standing question in evolutionary *** the bluefin killifish Lucania goodei,male coloration is *** can produce either red or yellow coloration in their anal fins,and both color morphs are present in all *** 2 morphs are heritable and how they are maintained in nature is ***, we tested 2 mechanisms for the maintenance of the red/yellow color *** frequency-dependent mating success predicts that rare males have a mating advantage over common males. Spatial variation in fitness predicts that different color morphs have an advantage in different microhabitat *** a breeding experiment,we tested these hypotheses by creating populations with different ratios of red to yellow males (5 red:1 yellow;1 red:5 yellow)and determining male mating success on shallow and deep spawning *** found no evidence of negative frequency-dependent mating *** morphs tended to have higher mating success, and this was particularly so on shallow spawning ***,on deep substrates,red males enjoyed higher mating success than yellow males,particularly so when red males were rare. However,yellow males did not have an advantage at either depth nor when *** suggest that preference for red males is expressed in deeper water,possibly due to alterations in the lighting ***,male pigment levels were correlated with one another and predicted male mating ***,pigmentation plays an important role in male mating success.

关键词： carotenoid color polymorphism environmental heterogeneity melanin negative frequency dependence pterin

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Effect of divalent cations(Co^(2+) and Ni^(2+)) on microstructure,physical properties and application of NdFeO_(3)

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Journal of Rare Earths 2025年第1期43卷 89-97,I0004页

作者： m.m.Arman materials Science Lab(1) Physics DepartmentFaculty of ScienceCairo UniversityGiza12613Egypt

The nanocrystalline samples Nd_(1-x)m_(x)FeO_(3)(x=0.0 and 0.1;m:Co^(2+)and Ni^(2+))were prepared using the citrate combustion *** X-ray diffraction(XRD)pattern confirmed that the nanoparticles were synthesized in an orthorhombic *** particle size of Nd_(1-x)m_(x)FeO_(3) is in the range of 29-59 *** selected area electron diffraction(SAED)indicates the samples were prepared in a polycrystalline *** samples Nd_(1-x)m_(x)FeO_(3)(x=0.0 and 0.1;m:Co^(2+)and Ni^(2+))have anti ferromagnetic *** Fe^(3+)spins are aligned antiparallel,forming the antiferromagnetic(AFm)properties,which are affected by many factors such as the bond angle between the Fe^(3+)(Fe^(3+)-O_(2)--Fe^(3+))and the Dzyaloshinskii-moriya(D-m)*** doping of Co^(2+)and Ni^(2+)ions in NdFeO_(3) enhances the magnetic properties of the NdFeO_(3).The saturation magnetization(ms)of Nd_(0.90)Co_(0.10)FeO_(3) increases 1.8times more than that of NdFeO_(3).The exchange bias field(HEX)of the Co-doped sample is two times greater than that of NdFeO_(3).The magnetic anisotropy constant(K)of the 10%Co-doped sample increases by 11 factors compared to that of NdFeO_(3).The Tauc plot illustrates that the samples have a direct optical *** divalent cation substitution(Co^(2+)and Ni^(2+))decreases the optical band gap of NdFeO_(3),leading to the recommendation of using the samples Nd_(0.90)Co_(0.10)FeO_(3) and Nd_(0.90)Ni_(0.10)FeO_(3) in photocatalysis of dye degradation from *** removal efficiencies of Cr6+at pH=6 are 88.06%,85.54%,and 85.52%for the samples NdFeO_(3),Nd_(0.90)Co_(0.10)FeO_(3),and Nd_(0.90)Ni_(0.10)FeO_(3),*** Freundlich isotherm mode is the best-fit model for NdFeO_(3) to adsorb Cr6+ions from aqueous solutions.

关键词： Optical properties Nanoparticles magnetic properties Perovskites Removal efficiency Rareearths

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Nonlinear forced vibration in a subcritical regime of a porous functionally graded pipe conveying fluid with a retaining clip

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Applied mathematics and mechanics(English Edition) 2025年第1期46卷 101-122页

作者： m.GHOLAmI m.EFTEKHARI Department of mechanical Engineering Shahid Bahonar University of Kerman

This study examines the nonlinear behaviors of a clamped-clamped porous pipe made of a functionally graded material(FGm) that conveys fluids and is equipped with a retaining clip, focusing on primary resonance and subcritical dynamics. The nonlinear governing equations for the FGm pipe are derived by the extended Hamilton's principle, and subsequently discretized through the application of the Galerkin *** direct method of multi-scales is then used to solve the derived equations. A thorough analysis of various parameters, including the clip stiffness, the power-law index, the porosity, and the clip location, is conducted to gain a comprehensive understanding of the system's nonlinear dynamics. Through the analysis of the first natural frequency, the study highlights the influence of the flow velocity and the clip stiffness, while the comparisons with metallic pipes emphasize the role of FGm composition. The examination of the forced response curves reveals saddle-node bifurcations and their dependence on parameters such as the detuning parameter and the power-law index, offering valuable insights into the system's nonlinear resonant behavior. Furthermore, the frequency-response curves illustrate the hardening nonlinearities influenced by factors such as the porosity and the clip stiffness, revealing nuanced effects on the system response and resonance characteristics. This comprehensive analysis enhances the understanding of nonlinear behaviors in FGm porous pipes with a retaining clip, providing key insights for practical engineering applications in system design and optimization.

关键词： functionally graded material (FGm) pipe conveying fluid O175.2 porosity primary resonance retaining clip subcritical regime

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Three-dimensional nanostructured Co_(2)VO_(4)-decorated carbon nanotubes for sodium-ion battery anode materials

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Rare metals 2023年第12期42卷 4060-4069页

作者： Yi Zhang Zhen Zhang Sheng Yu Hannah m.johnson De-Cheng Zhao Su-Chong Tan Zheng-Dao Pan Zhou-Lu Wang Yu-Tong Wu Xiang Liu School of Energy Sciences and Engineering Nanjing Tech UniversityNanjing 211816China Department of Chemistry Washington State UniversityPullman 99164USA

Since Co_(2)VO_(4) possesses a solid spinel structure and a high degree of stability,it has gained interest as a possible anode material for sodium-ion ***,the application of this electrode material is still hampered by its poor electrical conductivity and severe volume *** Co_(2)VO_(4) nanoparticles(CVO)were grown on carbon nanotubes(CNTs)by a simple solvothermal method to form string-like conductive networks(CVO/CNTs).The flexible and highly conductive three-dimensional(3D)carbon nano tubes and small-sized CVO NPs can enhance the rapid transport of electrons,thereby enhancing the conductivity of the ***-like conductive network structures have a larger specific surface area,enhancing electron/ion transmission by fully contacting the *** findings demonstrate the superior Na^(+)storing capability of the CVO/CNTs *** battery has a great rate performance(148.2 mAh·g^(-1)at 5 A·g^(-1))and outstanding long-term cycling performance(147.3 mAh·g^(-1)after 1000 cycles at 1A·g^(-1)).In high-rate,long-cycle sodium-ion batteries,CVO/CNTs composites offer a wide range of possible applications.

关键词： Sodium-ion batteries(SIBs) Co_(2)VO_(4) Carbon nanotubes(CNTs) Anode Long-cycle

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Honeycomb-spiderweb-inspired self-similar hybrid cellular structures for impact applications

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Defence Technology(防务技术) 2025年第1期43卷 182-200页

作者： K.Tewari m.K.Pandit m.m.mahapatra P.R.Budarapu School of mechanical Sciences Indian Institute of Technology BhubaneswarBhubaneswar752050India

Inspired by nature's self-similar designs,novel honeycomb-spiderweb based self-similar hybrid cellular structures are proposed here for efficient energy absorption in impact *** energy absorption is enhanced by optimizing the geometry and topology for a given *** proposed hybrid cellular structure is arrived after a thorough analysis of topologically enhanced self-similar *** optimized cell designs are rigorously tested considering dynamic loads involving crush and high-velocity bullet ***,the influence of thickness,radial connectivity,and order of patterning at the unit cell level are also *** maximum crushing efficiency attained is found to be more than 95%,which is significantly higher than most existing traditional *** on,the first and second-order hierarchical self-similar unit cell designs developed during crush analysis are used to prepare the cores for sandwich *** tests are performed on the developed sandwich structures using the standard 9-mm *** influence of multistaging on impact resistance is also investigated by maintaining a constant total thickness and mass of the sandwich ***,in order to avoid layer-wise weak zones and hence,attain a uniform out-of-plane impact strength,off-setting the designs in each stage is *** sandwich structures with first and second-order self-similar hybrid cores are observed to withstand impact velocities as high as 170 m/s and 270 m/s,respectively.

关键词： Sandwich structures Honeycomb-spider web inspired Self-similar hierarchy Crush analysis High-velocity impact Strong and weak zones multistaging

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Discovering causal models for structural,construction and defense-related engineering phenomena

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Defence Technology(防务技术) 2025年第1期43卷 60-79页

作者： m.Z.Naser School of Civil&Environmental Engineering and Earth Sciences(SCEEES) Clemson UniversityClemsonSouth Carolina 29634USA The Artificial Intelligence Research Institute for Science and Engineering(AIRISE) Clemson UniversityClemsonSouth Carolina 29634USA

Causality,the science of cause and effect,has made it possible to create a new family of *** models are often referred to as causal *** those of mathematical,numerical,empirical,or machine learning(mL)nature,causal models hope to tie the cause(s)to the effect(s)pertaining to a phenomenon(i.e.,data generating process)through causal *** paper presents one of the first works at creating causal models in the area of structural and construction *** this end,this paper starts with a brief review of the principles of causality and then adopts four causal discovery algorithms,namely,PC(Peter-Clark),FCI(fast causal inference),GES(greedy equivalence search),and GRa SP(greedy relaxation of the sparsest permutation),have been used to examine four phenomena,including predicting the load-bearing capacity of axially loaded members,fire resistance of structural members,shear strength of beams,and resistance of walls against impulsive(blast)*** from this study reveal the possibility and merit of discovering complete and partial causal ***,this study also proposes two simple metrics that can help assess the performance of causal discovery algorithms.

关键词： Causality Causal discovery Directed acyclic graphs machine learning metrics

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Transport mechanism in chemically reactive hybrid nanofluid flow containing gyrotactic micro-organisms over a curved oscillatory surface

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Applied mathematics and mechanics(English Edition) 2025年第1期46卷 177-192页

作者： m.NAVEED m.ImRAN T.ASGHAR Z.ABBAS Department of mathematics Division of Science and TechnologyUniversity of Education Department of mathematics The Islamia University of Bahawalpur

This paper examines the transport analysis, including both heat transfer and mass transfer, in hybrid nanofluid flow containing gyrotactic microorganisms towards a curved oscillatory surface. The influence of magnetic fields is also inspected in terms of their physical characteristics. To depict the phenomena of transport, modified versions of both Fick's and Fourier's laws are used. Additionally, the characteristics of both heterogeneous and homogeneous chemical reactions are also incorporated. Utilizing a curvilinear coordinate system, the flow problem is formulated as partial differential equations(PDEs)for momentum, concentration, microorganism field, and energy. An analytical solution to the obtained flow equations is achieved utilizing the homotopy analysis method(HAm).The effects of significant flow parameters on the pressure and microorganism fields, velocity, oscillation velocity, concentration, and temperature distributions are shown via graphs. Furthermore, the variations in skin friction, mass transfer rate, heat transfer rate, and local motile number due to different involved parameters are presented in tables and are analyzed in detail. Graphical results indicate that the curves of velocity and temperature fields are enhanced as the values of the solid volume fraction variables *** is also verified that the concentration rate field decreases as the values of the homogeneous reaction strength parameter and the radius of curvature parameter increase, and it increases with the Schmidt number and the heterogeneous reaction strength *** outcomes show a favorable response of the motile number to advanced values of the Peclet number, the Schmidt number, the microorganism difference parameter, and the bio-convective Lewis number.

关键词： analytical solution Cattaneo-Christov heat and mass flux chemical reaction gyrotactic microorganism hybrid nanofluid O368 oscillating curved stretchable sheet

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SVX/硅条探测器的研究

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核电子学与探测技术 1997年第1期17卷 28-32页

作者： L.Bagby m.johnson R.Lipton 顾维新 FenmilabNationalAcceleratorLaboratory 中国科学院高能物理所北京100039

交流耦合的硅条探测器有较高的电压跨接在耦合电容上面,坏的耦合电容使约50V 电压加到 SVX 器件,测量了坏的耦合电容对 SVXD(rod soft 3 μm)、SVXH(rad soft 1.2 μm)和 SVX2b(tad soft 1.2 μm)放大器/读出器件的影响.试验结果表明,... 详细信息

交流耦合的硅条探测器有较高的电压跨接在耦合电容上面,坏的耦合电容使约50V 电压加到 SVX 器件,测量了坏的耦合电容对 SVXD(rod soft 3 μm)、SVXH(rad soft 1.2 μm)和 SVX2b(tad soft 1.2 μm)放大器/读出器件的影响.试验结果表明,当一个过载电压直接加到一个 SVX 道时,相邻的一些道发生饱和,这种效应是由于在 SVX 基片内的电流扩散而不是探测器的表面电流形成的。文中讨论了饱和量大小和可能的解决途径。

关键词：硅条探测器 SVX读出器件饱和粒子径迹

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Regression analysis of squeezing-induced hybrid nanofluid flow in Darcy-Forchheimer porous medium

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Applied mathematics and mechanics(English Edition) 2025年第1期46卷 193-208页

作者： K.mUHAmmAD m.SARFRAZ Department of Humanities and Sciences School of Electrical Engineering and Computer Science National University of Sciences and Technology Department of mathematics Quaid-i-Azam University

This article presents a mathematical model addressing a scenario involving a hybrid nanofluid flow between two infinite parallel plates. One plate remains stationary, while the other moves downward at a squeezing velocity. The space between these plates contains a Darcy-Forchheimer porous medium. A mixture of water-based fluid with gold(Au) and silicon dioxide(Si O2) nanoparticles is formulated. In contrast to the conventional Fourier's heat flux equation, this study employs the Cattaneo-Christov heat flux equation. A uniform magnetic field is applied perpendicular to the flow direction, invoking magnetohydrodynamic(mHD) effects. Further, the model accounts for Joule heating, which is the heat generated when an electric current passes through the fluid. The problem is solved via NDSolve in mATHEmATICA. Numerical and statistical analyses are conducted to provide insights into the behavior of the nanomaterials between the parallel plates with respect to the flow, energy transport, and skin *** findings of this study have potential applications in enhancing cooling systems and optimizing thermal management strategies. It is observed that the squeezing motion generates additional pressure gradients within the fluid, which enhances the flow rate but reduces the frictional drag. Consequently, the fluid is pushed more vigorously between the plates, increasing the flow velocity. As the fluid experiences higher flow rates due to the increased squeezing effect, it spends less time in the region between the plates. The thermal relaxation, however, abruptly changes the temperature, leading to a decrease in the temperature fluctuations.

关键词： convective boundary condition Darcy-Forchheimer medium hybrid nanofluid Joule heating magnetohydrodynamic (mHD) numerical solution O175.2 O361 regression analysis squeezing flow

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