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World Journal of Gastroenterology 2016年第30期22卷 6800-6816页

作者： mahmoud Fathy Dondeti Eman Anwar El-Maadawy Roba mohamed Talaat Genetic Engineering and Biotechnology Research Division National Research Centre Molecular Biology Department Genetic Engineering and Biotechnology Research Institute University of Sadat City

Hepatocellular carcinoma(HCC) is a primary liver cancer, which is one of the most prevalent cancers among humans. Many factors are involved in the liver carcinogenesis as lifestyle and environmental factors. Hepatitis virus infections are now recognized as the chief etiology of HCC; however, the precise mechanism is still enigmatic till now. The inflammation triggered by the cytokine-mediated immune response, was reported to be the closest factor of HCC development. Cytokines are immunoregulatory proteins produced by immune cells, functioning as orchestrators of the immune response. Genes of cytokines and their receptors are known to be polymorphic, which give rise to variations in their genes. These variations have a great impact on the expression levels of the secreted cytokines. Therefore, cytokine gene polymorphisms are involved in the molecular mechanisms of several diseases. This piece of work aims to shed much light on the role of cytokine gene polymorphisms as genetic host factor in hepatitis related HCC.

关键词： Hepatocellular carcinoma Hepatitis C virus Hepatitis B virus Cytokines Polymorphism

Carbonate rocks resistivity determination using dual and triple porosity conductivity models

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Petroleum 2020年第1期6卷 35-42页

作者： Zeeshan Tariq mohamed mahmoud Hasan Al-Youssef Mohammad Rasheed Khan Department of Petroleum Engineering King Fahd University of Petroleum&MineralsDhahran31261Saudi Arabia

The rocks may be classified as Archie rocks or Non-Archie rocks,depending on the link between pore structure and resistivity of the *** carbonate rocks,keeping this factor in view,the applicability of Archie's law tends to be unreasonable and employing Archie's equation will ultimately lead to inaccurate estimates of the water *** investigators have reported models that forms a link between laboratory results and field well logs to determine water saturation in intricate pore *** case of complex systems,Archie's law fails to correctly define the resistivity-index *** addition,it is imperative to carry out investigations at lower saturation values in order to elaborate the non-Archie *** brings the dual and triple porosity conductivity models into the *** these models are essential in defining the considerable changes of the resistivity-index curves,both qualitatively and *** linkage between the two models is depicted electrically in series or in ***,it is possible to have a combination of the two *** a result,the experimental results can be modeled accurately using least *** work presents two models to determine water saturation in carbonate rocks,containing dual and triple porosity *** study also investigates the impact of different influential parameters such as saturation exponents,conductivity ratios,and pore volume fraction of each network systems,on the new ***,the effect of each parameter is individually studied and the sensitivity analysis on the RI curves is produced.A new approach to apply these models is also explained which requires the use of NMR log,mercury injection capillary pressure(MICP)measurement,and simple plotting techniques to determine the water *** proposed new models help petrophysicists to estimate water saturation in Non-Archie rocks,containing double and triple porosity network systems.

关键词： Dual porosity Triple porosity Carbonate rocks Water saturation models

Effective damping of local low frequency oscillations in power systems integrated with bulk PV generation

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Protection and Control of Modern Power Systems 2021年第1期6卷 512-524页

作者： Ahmed Hesham Abd El-Kareem mohamed Abd Elhameed mahmoud M.Elkholy Operation Engineer at New Capital Power Plant New Capital CityEgypt Electrical Power and Machines Department Faculty of EngineeringZagazig UniversityZagazigEgypt

High penetration of renewable sources into conventional power systems results in reduction of system inertia and noticeable low-frequency oscillations (LFOs) in the rotor speed of synchronous generators. In this paper, we propose effective damping of LFOs by incorporating a supplementary damping controller with a photovoltaic (PV) generating station, where the parameters of this controller are coordinated optimally with those of a power system stabilizer (PSS). The proposed method is applied to damp local electromechanical modes by studying a system comprising a synchronous generator and a PV station connected to an infinite bus. The PV station is modeled following the instructions of the Western Electricity Coordinating Council. The problem is modeled as an optimization problem, where the damping ratio of the electromechanical modes is designed as the objective function. Constraints including upper and lower limits of decision parameters and damping ratio of other modes are considered by imposing penalties on the objective function. Different optimization algorithms are used to pursue the optimal design, such as political, improved gray wolves and equilibrium optimizers. The results validate the effectiveness of the proposed controller with PSS in damping local modes of oscillations.

关键词： Low frequency oscillations Damping controller PV WECC

Impact of biliary complications on quality of life in live-donor liver transplant recipients

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World Journal of Hepatology 2021年第10期13卷 1405-1416页

作者： Reginia Nabil Guirguis ehab Hasan Nashaat Azza Emam Yassin Wesam Ahmed Ibrahim Shereen A Saleh mohamed Bahaa mahmoud El-Meteini mohamed Fathy Hany Mansour Dabbous Iman Fawzy Montasser Manar Salah Ghada Abdelrahman mohamed Department of Internal Medicine Gastroenterology and Hepatology UnitFaculty of MedicineAin Shams UniversityCairo 11591Egypt Department of General Surgery Faculty of MedicineAin Shams UniversityCairo 11591Egypt Department of Tropical Medicine Faculty of MedicineAin Shams UniversityCairo 11591Egypt

BACKGROUND Despite significant advancements in liver transplantation(LT)surgical procedures and perioperative care,post-LT biliary complications(BCs)remain a significant source of morbidity,mortality,and graft *** addition,data are conflicting regarding the health-related quality of life(HRQoL)of LT ***,the success of LT should be considered in terms of both the survival and recovery of *** To assess the impact of BCs on the HRQoL of live-donor LT recipients(LDLT-Rs).METHODS We retrospectively analysed data for 25 LDLT-Rs who developed BCs post-LT between January 2011 and December 2016 at our *** Short Form 12 version 2(SF 12v2)health survey was used to assess their *** also included 25 LDLT-Rs without any post-LT complications as a control *** The scores for HRQoL of LDLT-Rs who developed BCs were significantly higher than the norm-based scores in the domains of physical functioning(P=0.003),role-physical(P<0.001),bodily pain(P=0.003),general health(P=0.004),social functioning(P=0.005),role-emotional(P<0.001),and mental health(P<0.001).No significant difference between the two groups regarding vitality was detected(P=1.000).The LDLT-Rs with BCs had significantly lower scores than LDLT-Rs without BCs in all HRQoL domains(P<0.001)and the mental(P<0.001)and physical(P=0.0002)component summary *** The development of BCs in LDLT-Rs causes a lower range of improvement in HRQoL.

关键词： Live-donor liver transplantation Quality of life The Short Form 12 version 2 Cirrhosis Biliary complications Mental health

4-Port Octagonal Shaped MIMO Antenna with Low Mutual Coupling for UWB Applications

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Computer Modeling in Engineering & Sciences 2023年第8期136卷 1999-2015页

作者： mahmoud A.Abdelghany mohamed Fathy Abo Sree Arpan Desai Ahmed A.Ibrahim Electrical Engineering Department College of EngineeringPrince Sattam bin Abdulaziz UniversityWadi Addwasir11991Saudi Arabia Electronic and Communication Department Arab Academy for ScienceTechnology and Maritime TransportCairo11865Egypt Department of Electronics and Communication Engineering CSPITCharotar University of Science and Technology(CHARUSAT)Changa388421India Electronics and Communications Engineering Department Minia UniversityEl-Minia61519Egypt

A4-port multiple-input multiple-output(MIMO)antenna exhibiting lowmutual coupling andUWBperformance is *** octagonal-shaped four-antenna elements are connected with a 50microstrip feed line that is arranged rotationally to achieve the orthogonal polarization for improving the MIMO system *** antenna has a wideband impedance bandwidth of 7.5GHz with S11<−10 dB from(103.44%)3.5–11GHz and inter-element isolation higher than 20 *** validation is carried out by verifying the simulated and measured results after fabricating the *** results in the form of omnidirectional radiation patterns,peak gain(≥4 dBi),and Envelope Correlation Coefficient(ECC)(≤0.01)are extracted to validate the suggested antenna ***,time-domain analysis was investigated to demonstrate the operation of the suggested antenna in wideband ***,the simulated and experimental outcomes have almost similar tendenciesmaking the antenna suitable for its use in UWBMIMOapplications.

关键词： MIMO antenna low mutual coupling time domain analysis UWB antenna

Novel Synthesis of Some Phthalazinone Derivatives

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Chinese Journal of Chemistry 2011年第7期29卷 1446-1450页

作者： mahmoud, mahmoud R. Abou-Elmagd, Wael S.I. Derbala, Hamed A. Hekal, mohamed H. Chemistry Department Faculty of Science Ain Shams University Abassia 11566 Cairo Egypt

Dimethyl homophthalate condensed with isatin to give the unexpected five membered lactone 3 rather than the half ester 1 and the β-lactone 2. Treatment of compound 3 with excess hydrazine hydrate afforded phthalazinone carbohydrazide 4 which represents a novel method for the synthesis of phthalazinone derivatives. The carhohy- drazide 4 upon treatment with carbon disulphide afforded 1,3,4-oxadiazole derivative 5, which reacted with ethyl- chloroacetate to give the S-alkylated product 6. The structure of compound 3 compared with 2 was discussed using hyperchem professional （7） AM1 calculations, X-ray single crystal structure and complete spectral data.

关键词： phthalazinone carbohydrazide oxadiazole triazolo oxadiazole AMx calculation condensation

Maximizing the Benefit of Rate Transient Analysis for Gas Condensate Reservoirs

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Energy Engineering 2021年第5期118卷 1411-1423页

作者： mahmoud Abdo Tantawy Ahmed A.M.Elgibaly Ahmed mohamed Farag Faculty of Petroleum and Mining Engineering Suez UniversitySuezEgypt Abu Qir Petroleum Company AlexandriaEgypt

In recent years,many trials have been made to use the Rate Transient Analysis(RTA)techniques as a method to describe the gas condensate *** problem with using these techniques is the multi-phase behavior of the gas condensate ***,the Pressure Transient Analysis(PTA)is commonly used in this case to analyze the reservoir *** this paper,we are going to compare the results of both PTA and RTA of three wells in gas condensate *** comparison showed a great match between the results of the two mentioned techniques for the first time using a reference GOR of 75,000 SCF/***,we concluded that we could depend on RTA instead of PTA to spare the cost associated with the PTA in the gas condensate reservoirs.

关键词： Rate transient analysis production data analysis well testing permeability skin factor gas condensate

Biliary complications in recipients of living donor liver transplantation:A single-centre study

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World Journal of Hepatology 2021年第12期13卷 2081-2103页

作者： Reginia Nabil Guirguis ehab Hasan Nashaat Azza Emam Yassin Wesam Ahmed Ibrahim Shereen A Saleh mohamed Bahaa mahmoud El-Meteini mohamed Fathy Hany Mansour Dabbous Iman Fawzy Montasser Manar Salah Ghada Abdelrahman mohamed Gastroenterology and Hepatology Unit Department of Internal MedicineFaculty of MedicineAin Shams UniversityCairo 11591Egypt Department of General Surgery Faculty of MedicineAin Shams UniversityCairo 11591Egypt Department of Tropical Medicine Faculty of MedicineAin Shams UniversityCairo 11591Egypt

BACKGROUND Biliary complications(BCs)after liver transplantation(LT)remain a considerable cause of morbidity,mortality,increased cost,and graft *** To investigate the impact of BCs on chronic graft rejection,graft failure and *** From 2011 to 2016,215 adult recipients underwent right-lobe living-donor liver transplantation(RT-LDLT)at our *** excluded 46 recipients who met the exclusion criteria,and 169 recipients were included in the final ***’and recipients’demographic data,clinical data,operative details and postoperative course information were *** also reviewed the management and outcomes of *** were followed for at least 12 mo post-LT until December 2017 or graft or patient *** The overall incidence rate of BCs including biliary leakage,biliary infection and biliary stricture was 57.4%.Twenty-seven(16%)patients experienced chronic graft *** failure developed in 20(11.8%)patients.A total of 28(16.6%)deaths occurred during *** were a risk factor for the occurrence of chronic graft rejection and failure;however,mortality was determined by recurrent hepatitis C virus *** Biliary complications after RT-LDLT represent an independent risk factor for chronic graft rejection and graft failure;nonetheless,effective management of these complications can improve patient and graft survival.

关键词： Biliary complications Living donor liver transplantation Retrospective analysis Bile leak Biliary stricture Risk factors Mortality Graft rejection

Impact of designed infection control educational program on nurses’knowledge and compliance with standard precautions at maternity hospitals

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Journal of Integrative Nursing 2023年第2期5卷 138-144页

作者： Fatma ZAGHLOUL-mahmoud mohamed GAMAL-MOSTAFA Walaa mahmoud-ABDEL-RAHMAN Maternal and Newborn Health Nursing Department Faculty of NursingCairo UniversityCairoEgypt Nursing Administration Department Faculty of NursingCairo UniversityCairoEgypt

Objectives:This study aimed to assess the nurses’knowledge and compliance with infection control standard precautions and evaluate the impact of the designed infection control educational program on nurses’knowledge and compliance with standard precautions at the maternity *** and Methods:A quasi‑experimental one‑group pretest‑posttest design was used on convenient sample of 60 nurses working at Obstetrics and Gynecological hospital in Cairo University Hospital,Kasr El Ainy,who received“designed infection control educational program”for 6 *** data were collected through the questionnaire comprising demographics,knowledge,and compliance with standard precautions *** nurses’knowledge and compliance score were compared before and after ***:The studied nurses had higher level of knowledge(85.3%)and compliance(92.8%)regarding infection control standard precautions after the educational program compared to before the *** results revealed statistically significant difference between before and after the program regarding nurses’knowledge score(15.5±2.9 vs.17.1±1.6,P<0.001)and compliance score(58.5±13.2 vs.74.3±5.1,P<0.001).In addition,there was insignificant relation between nurses’knowledge and compliance with standard precautions both before(r=0.952,P=0.474)and after educational program(r=0.164,P=0.223).Conclusion:The nurses’level of knowledge and compliance regarding infection control standard precautions was significantly improved after the ***,it is recommended that periodical educational programs regarding the standard precautions of infection control are essential for nurses at maternity hospital.

关键词： Compliance infection control knowledge maternity nursing standard precautions