Biliary complications in recipients of living donor liver transplantation:A single-centre study
作者机构:Gastroenterology and Hepatology UnitDepartment of Internal MedicineFaculty of MedicineAin Shams UniversityCairo 11591Egypt Department of General SurgeryFaculty of MedicineAin Shams UniversityCairo 11591Egypt Department of Tropical MedicineFaculty of MedicineAin Shams UniversityCairo 11591Egypt
出 版 物:《World Journal of Hepatology》 (世界肝病学杂志(英文版)(电子版))
年 卷 期:2021年第13卷第12期
页 面:2081-2103页
学科分类:1002[医学-临床医学] 100210[医学-外科学(含:普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学]
主 题:Biliary complications Living donor liver transplantation Retrospective analysis Bile leak Biliary stricture Risk factors Mortality Graft rejection
摘 要:BACKGROUND Biliary complications(BCs)after liver transplantation(LT)remain a considerable cause of morbidity,mortality,increased cost,and graft *** To investigate the impact of BCs on chronic graft rejection,graft failure and *** From 2011 to 2016,215 adult recipients underwent right-lobe living-donor liver transplantation(RT-LDLT)at our *** excluded 46 recipients who met the exclusion criteria,and 169 recipients were included in the final ***’and recipients’demographic data,clinical data,operative details and postoperative course information were *** also reviewed the management and outcomes of *** were followed for at least 12 mo post-LT until December 2017 or graft or patient *** The overall incidence rate of BCs including biliary leakage,biliary infection and biliary stricture was 57.4%.Twenty-seven(16%)patients experienced chronic graft *** failure developed in 20(11.8%)patients.A total of 28(16.6%)deaths occurred during *** were a risk factor for the occurrence of chronic graft rejection and failure;however,mortality was determined by recurrent hepatitis C virus *** Biliary complications after RT-LDLT represent an independent risk factor for chronic graft rejection and graft failure;nonetheless,effective management of these complications can improve patient and graft survival.