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Brain Science Advances 2024年第1期10卷 57-71页

作者： Gehan S.Georgy Ibrahim M.Ibrahim Laila Mohamed E.Amer ebtehal mohammad f. Pharmacology Department Egyptian Drug Authority(EDA)Giza P.O.29Egypt Molecular Drug Evaluation Department Egyptian Drug Authority(EDA)Giza P.O.29Egypt Histology Department Faculty of MedicineAl-Azhar UniversityDamietta P.O.11651Egypt

Dapoxetine is a newer anti-depressant that is used f.r severe f.rms of.depression via selective serotonin reuptake inhibition *** aimed to evaluate the ef.ect of.dif.erent doses of.dapoxetine lonely or with acetaminophen(AMP).Seven groups of.albino rats were used where dapoxetine was administered orally at the doses of.3,5,and 8 mg/kg body weight f.r a period of.14 days in groups 2,4,and 6,***(67.5 mg/kg body weight)was co-administered with dapoxetine(3,5,and 8 mg/kg body weight)f.r 14 days in groups 3,5 and 7,*** in mid and high dose plus AMP increased body weight and hematological *** and rearing were declined with mid and high doses of.dapoxetine+AMP,contrary to *** was decreased with high doses of.dapoxetine+*** dose of.dapoxetine+AMP induced lowering of.serotonin and dopamine as well as increasing of.*** derived neurotrophic f.ctor was decreased in all *** stress biomarkers were augmented with high dose of.dapoxetine+*** doses of.dapoxetine and/or AMP induced loss of.the Purkinje cell layer at *** high dose of.dapoxetine+AMP denotes behavioral,histopathological and neurochemical alterations,even though no serotonin syndrome occurs.

关键词： acetaminophen dapoxetine neurotransmitters oxidative stress biomarkers

Artif.cial ground f.eezing of.underground mines in cold regions using thermosyphons with air insulation

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International Journal of.Mining Science and Technology 2024年第5期34卷 643-654页

作者： Ahmad f.Zueter mohammad Zolf.gharroshan Navid Bahrani Agus P.Sasmito Department of.Civil and Resource Engineering Dalhousie UniversityHalifax B3H4R2Canada Department of.Mining Engineering McGill UniversityMontreal H3A0E8Canada

Current practice of.underground artif.cial ground f.eezing(AGf.typically involves huge ref.igeration systems of.large economic and environmental *** this study,a novel AGf.technique is proposed deploying available cold wind in cold *** is achieved by a static heat transf.r device called thermosyphon equipped with an air insulation layer.A ref.igeration unit can be optionally integrated to meet additional cooling *** introduction of.air insulation isolates the thermosyphon f.om ground zones where f.eezing is not needed,resulting in:(1)steering the cooling resources(cold wind or ref.igeration)towards zones of.interest;and(2)minimizing ref.igeration *** design is demonstrated using well-validated mathematical models f.om our previous work based on two-phase enthalpy method of.the ground coupled with a thermal resistance network f.r the *** Canadian mines are considered:the Cigar Lake Mine and the Giant *** results show that our proposed design can speed the f.eezing time by 30%at the Giant Mine and by two months at the Cigar Lake ***,a cooling load of.2.4 GWh can be saved at the Cigar Lake ***,this study provides mining practitioners with sustainable solutions of.underground AGf.

关键词： Artif.cial ground f.eezing Underground mining Sustainable mining Thermosyphon Air insulation Cold regions

Auto-tuning PVT data using multi-objective optimization: Application of.NSGA-Ⅱ algorithm

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Petroleum 2024年第1期10卷 135-149页

作者： Abdolhadi Zarif. mohammad Madani mohammad Jaf.rzadegan Reservoir Engineering Systems Petroleum Engineering Department Main Office Building of National Iranian South Oil Company (NISOC) Combined Planning Management National Iranian Oil Company (NIOC) Reservoir Engineering Division Petroleum Engineering Department Petroleum Engineering and Development Company (PEDEC)

Reservoir simulation is known as perhaps the most widely used, accurate, and reliable method f.r f.eld development in the petroleum industry. An integral part of.a reliable reservoir simulation process is to consider robust and rigorous tuned EOS models. Traditionally, EOS models are tuned iteratively through arduous workf.ows against experimental PVT data. However, this comes with a number of.drawbacks such as f.rcingly using weight f.ctors, which upon alteration adversely af.ects the optimization *** objective of.the current work is thus to introduce an auto-tune PVT matching tool using NSGA-II multi-objective optimization. In order to illustrate the robustness of.the presented technique, three dif.erent PVT samples are used, including two black-oil and one gas condensate sample. We utilize PengRobinson EOS during all the manual and auto-tuning processes. Comparison of.auto-tuned EOS-generated results with those of.experimental and computed statistical error values f.r these samples clearly show that the proposed method is robust. In addition, the proposed method, contrary to the manual matching process, provides the engineer with several matched solutions, which allows them to select a match based on the engineering background to be best amenable to the problem at hand. In addition, the proposed technique is f.st, and can output several solutions within less time compared to the traditional manual matching method.

关键词： Auto-tuning PVT Equation of.state NSGA-II Multi-objective optimization

Investigation of.material composition,design,and perf.rmance of.open-graded asphalt mixtures f.r semi-f.exible pavement:A comprehensive experimental study

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Journal of.Traf.ic and Transportation Engineering(English Edition) 2024年第1期11卷 92-116页

作者： mohammad Taghipoor Abolf.zl Hassani mohammad M.Karimi Department of.Civil and Environmental Engineering Tarbiat Modares UniversityTehranIran

The primary goal of.this study is the design and construction of.semi-f.exible pavement(Sf.)mixture in accordance with the engineering and mechanical *** study involves the use of.a range of.gradation curves,air void contents,cellulose and synthesized f.bers,and neat and modif.ed asphalt binders to prepare the open-graded asphalt(OGA)*** analyze the characteristics of.these mixtures,a variety of.test,namely binder drainage,semi-circular bending(SCB),Cantabro,wheel tracking,indirect tensile strength(ITS),and permeability tests were ***,to analyze the prepared grouting material,f.exural strength,compressive strength,and f.uidity tests were *** the f.nal stage,Sf. was compared to HMA in terms of.engineering characteristics and *** to the results,Sf. was more resistant to skid,rutting,f.re,and moisture damage,while HMA had a better perf.rmance in f.acture tests,including SCB *** to the results of.the mechanical perf.rmance tests conducted on OGA mixtures,the highest and lowest values f.r air void content to achieve the highest mechanical perf.rmance level were 30%-35%and 25%,***,based on the laboratory results,it was determined that the required void ratio f.r constructing OGA mixtures was 24%-26%based on the bitumen type and f.bers amount in the ***,Sf. mixture can be regarded as a viable alternative to common pavements thanks to its high resistance to rutting and moisture damage,long f.eezing-thawing f.tigue lif.,and adequate f.re and skid resistance.

关键词： Semi-f.exible pavement mixture Open-graded asphalt mixture Engineering properties Cantabro test Hot mix asphalt

Recent Progress in Bionic Hydrogels f.r Articular Cartilage:Tribological and Mechanical Characteristics

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Journal of.Bionic Engineering 2024年第2期21卷 653-673页

作者： mohammad Javan Almasi Dangsheng Xiong School of.Materials Science and Engineering Nanjing University of Science and TechnologyNanjing210094China

Cartilage regeneration and repair are considered clinical challenges since cartilage has limited capability f.r *** tissue-engineered materials have the ability to repair cartilage,they have weak mechanical characteristics and cannot resist long-term *** the other hand,surgery to replace the joint is f.equently done to treat signif.cant cartilage deterioration these ***,the materials that are being used f.r replacement have high f.iction coef.icients,lack shock absorption f.nctions,and lack *** research on natural articular cartilage structure and f.nction may lead to bionic hydrogels,which have suitable physicochemical and biological characteristics(e.g.,tribological and mechanical properties and the ability to support loadbearing capability),but need *** on their tribological and mechanical characteristics,the current review highlights the most recent advancements of.bionic hydrogels used f.r articular cartilage,highlighting both the f.eld's recent progress and its potential f.r f.ture *** this reason,f.rstly,some important property improvement methods of.bionic hydrogels are discussed and then,the recent f.ndings of.various research on the making of.those bionic materials are provided and *** seems that by using some modif.cations such as product design,surf.ce treatments,animal tests,controlling the isoelectric point of.hydrogels,and computer simulation,the intended mechanical and tribological characteristics of.natural articular cartilage may be attained by the bionic hydrogels.

关键词： Bionic hydrogel Articular cartilage Mechanical property Tribological property Lubrication

Ultrasensitive plasmonic sensor based on MDM waveguide containing Persian Orsi window cavities f.r ref.active index and blood plasma sensing

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Optoelectronics Letters 2024年第7期20卷 406-411页

作者： mohammad Ghanavati mohammad Azim Karami School of.Electrical Engineering Iran University of Science and Technology

We developed a plasmonic ref.active index（RI） with a metal-dielectric-metal（MDM） structure that utilizes two Persian Orsi windows-like separated cavities with a high f.gure of.merit（f.M） and ultrasensitivity. The simulated and optimized Ag-air-Ag MDM sensor f.r surf.ce plasmon resonance（SPR） of.ers high RI sensitivity（SRI） and the ability to detect blood plasma concentration（BPC）. The results verif.ed that structural parameters have an ef.ect on S;RI;, f.ll width at half.maximum（f.HM）, f.M, sensitivity of.blood plasma（S;p;） f.r right and lef. peaks, whose values are 1 345.45 nm·RIU;-1;, 32 nm, 42.04 RIU;-1;, 0.26 and 0.19 nm·L·g;-1;, respectively. The proposed design opens a new horizon in sensor development.

关键词： A

The global stability and optimal control of.the COVID-19 epidemic model

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International Journal of.Biomathematics 2024年第1期17卷 1-28页

作者： f.ngsheng Chien Hassan Saberi Nik mohammad Shiraziant J.f.Gomez-Aguilar School of.f.nance and Accounting f.zhou University of.International Studies and Trade f.zhou 352020 P.R.China f.culty of.Business City university of Macao Macao 999078P.R.China Department of.Mathematics and Statistics University of.Neyshabur NeyshaburIran CONACyT-Tecnologico Nacional de Mécico/CENIDET Interior Internado Palmira S/N Col.Palmira C.P.62490CuernavacaMorelosMérico

This paper considers stability analysis of.a Susceptible-Exposed-Inf.cted-Recovered-Virus(SEIRV)model with nonlinear incidence rates and indicates the severity and weakness of.control f.ctors f.r disease *** Lyapunov f.nction using Volterra-Lyapunov matrices makes it possible to study the global stability of.the endemic equilibrium *** optimal control strategy is proposed to prevent the spread of.coronavirus,in addition to governmental *** objective is to minimize together with the quantity of.inf.cted and exposed individuals while minimizing the total costs of.treatment.A numerical study of.the model is also carried out to investigate the analytical results.

关键词： Global stability SEIRV epidemic model dynamical systems Volterra-Lyapunov stability optimal control

The modeling non-sequential double ionization of.helium atom under highintensity f.mtosecond laser pulses with shielding charge approximation

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Communications in Theoretical Physics 2024年第2期76卷 151-156页

作者： Marjan Zakavi mohammad Sabaeian Department of.Physics Faculty of ScienceShahid Chamran University of AhvazIran Center f.r Research on Laser and Plasma Shahid Chamran University of AhvazIran

In this study,we successf.lly extracted the‘knee structure’f.r non-sequential double ionization(NSDI)in the helium *** achieve this,f.r the f.rst time,we solved the time-dependent Schrödinger equation in three dimensions f.r the helium atom,utilizing the shielding charge *** f.ndings corroborate prior observations by Wang et al[Wang and Eberly,***.105,083001(2010)],demonstrating that NSDI occurs within a narrower time window in circular polarization compared to linear *** a result,the yield of.linear polarization was higher than that of.circular polarization,aligning with the previously reported ***,in the case of.circular polarization,the time window f.rther narrows with increasing intensity,attributed to a decrease in the time-of.f.ight.

关键词： NSDI knee structure TDSE shielding charge helium 3D-TDSE

Direct scaling of.residual displacements f.r bilinear and pinching oscillators

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Earthquake Engineering and Engineering Vibration 2024年第1期23卷 129-149页

作者： mohammad Saif.llah Vinay K.Gupta Department of.Civil Engineering Indian Institute of Technology KanpurKanpur 208016India

The estimation of.residual displacements in a structure due to an anticipated earthquake event has increasingly become an important component of.perf.rmance-based earthquake engineering because controlling these displacements plays an important role in ensuring cost-f.asible or cost-ef.ective repairs in a damaged structure af.er the *** attempt is made in this study to obtain statistical estimates of.constant-ductility residual displacement spectra f.r bilinear and pinching oscillators with 5%initial damping,directly in terms of.easily available seismological,site,and model *** of.the available models f.r the bilinear and pinching oscillators are usef.l when design spectra f.r a seismic hazard at a site are not *** statistical estimates of.a residual displacement spectrum are proposed in terms of.earthquake magnitude,epicentral distance,site geology parameter,and three model parameters f.r a given set of.ductility demand and a hysteretic energy capacity coef.icient in the case of.bilinear and pinching models,as well as f.r a given set of.pinching parameters f.r displacement and strength at the breakpoint in the case of.pinching model *** proposed scaling model is applicable to horizontal ground motions in the western *** earthquake magnitudes less than 7 or epicentral distances greater than 20 km.

关键词： residual displacement spectrum bilinear hysteresis model pinching hysteresis model nonlinear analysis scaling model

Interpretable Detection of.Malicious Behavior in Windows Portable Executables Using Multi-Head 2D Transf.rmers

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Big Data Mining and Analytics 2024年第2期7卷 485-499页

作者： Sohail Khan mohammad Nauman Computer Science Department Effat College of EngineeringEffat UniversityJeddah 23341Kingdom of Saudi Arabia

Windows malware is becoming an increasingly pressing problem as the amount of.malware continues to grow and more sensitive inf.rmation is stored on *** of.the major challenges in tackling this problem is the complexity of.malware analysis,which requires expertise f.om human *** developments in machine learning have led to the creation of.deep models f.r malware ***,these models of.en lack transparency,making it dif.icult to understand the reasoning behind the model’s decisions,otherwise known as the black-box *** address these limitations,this paper presents a novel model f.r malware detection,utilizing vision transf.rmers to analyze the Operation Code(OpCode)sequences of.more than 350000 Windows portable executable malware samples f.om real-world *** model achieves a high accuracy of.0.9864,not only surpassing the previous results but also providing valuable insights into the reasoning behind the *** model is able to pinpoint specif.c instructions that lead to malicious behavior in malware samples,aiding human experts in their analysis and driving f.rther advancements in the *** report our f.ndings and show how causality can be established between malicious code and actual classif.cation by a deep learning model,thus opening up this black-box problem f.r deeper analysis.

关键词： machine learning malware vision transf.rmers Windows Protable Executable(PE)