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Seismicity Study of botswana from 1966 to 2012

International Journal of Geosciences 2018年第12期9卷 707-718页

作者： bokani Nthaba Rapelang e. Simon Ghebrebrhan M. Ogubazghi botswana International University of Science and Technology (bIUST) Palapye Botswana Physics Department University of Botswana Gaborone Botswana Department of earth Sciences Eritrea Institute of Technology Asmara Eritrea

The history of botswana’s major seismic events has been initiated by two earthquakes that occurred on the 11th of September and 11th of October 1952 with ML Richter magnitudes of 6.1 and 6.7, respectively, in the Okavango Delta Region (ODR). Not much is known and well documented about the seismicity of a larger coverage of botswana primarily because over the years, local seismic stations were biased to the north-western part of botswana, to monitor the more seismogenic ODR. The objective of this study is to use data from the International Seismological Centre (ISC) bulletin for the period 1966-2012 to estimate the relative size distribution of seismic events (b-value), the rate of seismic activity (a-value), and associated stress condition prevailing in botswana to assist in the quest of hazard mitigation. This study shows that micro-seismic activities of magnitude ranging from 1.3 to 5.7 are distributed not only on the northern part of botswana, but also in other parts of the country such as the Southern (including Kweneng east and West), Central and eastern botswana. based on 327 events extracted from data compiled by the ISC, the frequency-magnitude distribution (FMD) of earthquakes in botswana from 1966 to 2012 was estimated with b-value and a-value for the entire catalogue found to be 1.2 and 6.3, respectively, implying a region of low stress dominated by small to moderate events. The minimum completeness magnitude (MC), a value that indicates the lowest magnitude above which all seismic events are reliably recorded was found to be 3.8. From this analysis, annual probabilities of occurrence for M4 and M5 events were found to be 67.2% and 4.3%, respectively, while M6 or larger event has an annual probability of 0.3%.

关键词： b-Value Catalogue Completeness Magnitude Okavango Delta Region Seismicity

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ORIGIN OF MONOAMINeRGIC INNeRVATION OF THe NUCLeUS RAPHe MAGNUS——A COMbINeD MONOAMINe HISTOCHeMISTRY AND FLUOReSCeNT ReTROGRADe TRACING STUDY IN THe RAT

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中国科学b辑(英文版) 1986年第6期29卷 599-608页

作者：董新文沈锷 Shanghai Institute of Physiology Academia Sinica Shanghai brain Research Institute Academia Sinica

by the use of the fluorescent retrograde tracer, Fast blue (Fb), in combination with monoamine fluorescence histochemistry, the origin of monoaminergic input to the region of the nucleus raphe magnus (NRM) was investigated in the rat. After mieroinjection of Fb into the NRM, a great number of Fb-laboled NA-containing cells were found in the region of the nucleus reticularis lateralis (corresponding to A1 NA areas), the reticular formation just dorsolateral to the nucleus olivaris inferior (corresponding to the A3 NA area), the ventral part of the locus coeruleus (A6 NA area), and the lateral parts of the nucleus raphe dorsalis (b7 area). In the other NA cell groups of the brain stem, Fb-labeled cells could not be observed. Serotoninergic input originating from nucleus raphe obscurus (b2), nucleus raphe pallidus (b1) and nucleus raphe pontis (bS-b6) to the NRM was also observed. A large number of cells containing serotonin (5-HT) in the b2 and b6 areas were labeled by Fb, while only a few Fb-labeled 5-HT

关键词： nucleus raphe dorsalis labeled ventral locus serotonin inferior retrograde illumination

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Synthesis and Chiral Separation of Fibratol, Isopropyl 2-(4-((4-chlorophenyl)(hydroxyl) methyl)-phenoxy)-2-methylpropanoate

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International Journal of Organic Chemistry 2018年第2期8卷 201-206页

作者： Amanda e. Kotheimer Wahajul Haq Ganesaratnam K. balendiran Department of Chemistry Youngstown State University One University Plaza Youngstown OH USA Medicinal Chemistry Division Central Drug Research Institute Lucknow India

Practical synthetic route for the formation of enantiomeric mixture of Isopropyl 2-(4-((4-chlorophenyl)(hydroxyl)methyl)phenoxy)-2-methylpropanoate (Fibratol 2a/b) from isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoate (Fenofibrate 1) has been developed. Method has also been established for the chiral separation of enantiomers of Fibratol 2a/b that is synthesized using the route mentioned above. The optical activity determined for enantiomerically separated Fibratol (2a) and Fibratol (2b) are -5.2° and 8.0° which reflect their ability to rotate plane polarized light counterclockwise (levo) and clockwise (dextro), respectively.

关键词： Reduction Chirality Optical Activity Fibrate

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Recent Developments in Topologies of Single-Phase buck-boost Inverters for Small Distributed Power Generators: An Overview

Recent Developments in Topologies of Single-Phase Buck-Boost...

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第4届国际电力电子及运动控制国际会议

作者： Yaosuo Xue, Liuchen Chang, Department of electrical and Computer engineering University of New brunswick Fredericton, Nb, Canada e3b 5A3 Pinggang Song School of electrical engineering east China Jiaotong University Nanchang, Jiangxi, China 330013

Unique requirements for small distributed power generation (DG) systems Include low cost, high efficiency, and tolerance for an extremely wide range of input voltage variations. The inverters In such systems not only perform functions such as normal dc-ac conversion, output power quality assurance, various protections and system controls, but also meet these requirements, which have driven the inverter development toward simpler topologies and structures, lower component counts, and tighter modular design. both single-stage and multiple-stage inverters have been developed for power conversion in DG systems. While single-stage inverters enjoy simple structure and low cost, they suffer from a limited range of input voltage variations and often a compromised system performance. On the other hand, multiple-stage inverters can accept a wide range of input voltage variations, but assume high cost, complicated structure, and low overall efficiency. This paper presents an overview of the development in the single-phase inverters for small distributed power generators with various circuit topologies and discussions as well as the Identification of recent development trends.

关键词： buck-boost inverters single-stage inverters multiple-stage inverters distributed power generation (DG)

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Treatment of Chronic Paronychia: A Double blind Comparative Clinical Trial Using Singly Vaseline, Nystatin and Fucidic Acid Ointment

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Journal of Cosmetics, Dermatological Sciences and Applications 2013年第4期3卷 250-255页

作者： Khalifa e. Sharquie Adil A. Noaimi Sunbul A. Galib Department of Dermatology & Venereology Baghdad Teaching Hospital Bagh- dad Iraq Department of Dermatology & Venereology College of Medicine University of Baghdad Baghdad Iraq Scientific Council of Dermatology & Venereology Iraqi Board for Medical Specializations Department of Dermatology & Venereology College of Medicine University of Baghdad Baghdad Iraq

background: Chronic paronychia is a chronic inflammatory reaction of the proximal and lateral nail folds of multifactorial in etiology like irritant, bacterial and monilial causes. but housewife work is a major cause of chronic paronychia. Objective: To assess the efficacy and prophylactic effects of Vaseline by occlusion of nail folds in comparison with nystatin ointment and fucidic acid in treatment of housewife chronic paronychia. Patients and Methods: This double, blinded, comparative therapeutic, clinical trial is conducted at the Department of Dermatology-baghdad Teaching Hospital from May 2010 to May 2011. eighty female housewife patients with chronic paronychia were included in this trial. They were divided into three groups according to the following therapeutic model: Group A treated by Vaseline consisted of 40 patients;Group b and Group C treated by nystatin ointment, fucidic acid ointment respectively and each group consisted of 20 patients. All demographic points related to the disease were recorded from all patients. Invented score system was applied to assess the severity of disease and the response to therapy. Patients had used therapy twice daily on the proximal and lateral nail folds. Treatment duration was 12 weeks. Results: Group A (Vaseline): The recovery rate after 12 weeks of treatment was 26 (65%) patients, while there was no recovery in 14 (35%) patients. Group b (Nystatin ointment): The recovery rate after 12 weeks was 13 (65%) cases and there was no recovery in 7 (35%) patients. Group C (Fucidic acid ointment): The recovery rate 12 weeks of treatment was 12 (60%) patients and there was no recovery in 8 (40%) patients. The earliest signs of recovery in all groups were decreased in nail fold tenderness, redness, swelling followed by improvement in the nail shape, then decreased in the separation of proximal nail fold from nail bed followed by re-growth of cuticle. There was significant difference in clinical response before and after therapy

关键词： Housewife Paronychia Vaseline Occlusive Therapy

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核医学中的机器学习:第二部分——神经网络与临床

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中华核医学与分子影像杂志 2021年第8期41卷 507-512页

作者：谢宗能(译) 颜建华(审校) 上海理工大学医疗器械与食品学院 200093 上海健康医学院、上海市分子影像学重点实验室 201318

第一部分概述了机器学习(ML)在核医学中的应用,第二部分重点介绍神经网络。该文先用一个例子说明神经网络是如何工作的,并讨论其潜在的应用。重点关注ML在图像重建、低剂量PeT、疾病检测以及诊断和预后预测的最新进展。目前在核医学中... 详细信息

第一部分概述了机器学习(ML)在核医学中的应用,第二部分重点介绍神经网络。该文先用一个例子说明神经网络是如何工作的,并讨论其潜在的应用。重点关注ML在图像重建、低剂量PeT、疾病检测以及诊断和预后预测的最新进展。目前在核医学中应用的ML算法呈现多样化,迫切需要对算法设计和结果指标解读进行规范,该文给出了一个规范清单以供业界参考和遵循。

关键词：机器学习核医学神经网络

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Rat adult stem cell differentiation into immature retinal cells

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Stem Cell Discovery 2012年第2期2卷 62-69页

作者： Ma Teresa González-Garza Jorge e. Moreno-Cuevas Servicio de Terapia Celular School of Medicine Tecnológico de Monterrey Monterrey México

Cell therapy has been proposed as an alternative treatment for retinal diseases. Applications involving stem cells have shown that undifferentiated cells fail to engraft and cannot convert to retinal cells. However, positive results have been reported for retinal precursor cells, suggesting that this approach is the best option. Unfortunately, the source of this cell type is controversial. Predifferentiated adult stem cells may provide an alternative source of cells. The present study proposes a sequential culture media aimed at inducing cells from this source into a preretinal-like lineage. Rat bone marrow stem cells were cultivated in a neuroinduction mix medium for 24 h. The sequence involves immunocytochemistry to detect nestin and tubulin III to demonstrate the cell’s neuronal lineage, followed by incubation in retinal-induction mixed medium for 24 h. RT-PCR was performed to detect expression of brn3b, Pax6, THY1.1, Opn4, and Ath5 genes. Immunocytochemistry results showed increased expression of nestin and tubulin III after 24 h of incubation in the neuroinduction medium. RT-PCR showed slightly increased expression of Pax6, THY1.1, and Opn4 after 48 h of sequential incubation in the neuroinduction and predifferentiation media. brn3b and Ath5 gene expression increased markedly. These results suggest that mesenchymal stem cells have a high predisposition to differentiate into preretinal-like cells with minimal time in culture. These cells may provide a viable alternative for restoring damaged retinas.

关键词： Cell Therapy MSC Regenerative Medicine Retinal Diseases Stem Cells

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土尔扈特“鄂尔齐”制度考

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清史研究 2021年第5期127卷 140-147页

作者：巴·巴图巴雅尔新疆师范大学历史与社会学院乌鲁木齐830017

“鄂尔齐”(oro i)有汗位继承人、储君和汗储等意思。俄文里的“намeстника”比较接近“鄂尔齐”一词的含义。“鄂尔齐”的出现与该制度的施行,跟土尔扈特汗国(国外文献一般称作“卡尔梅克汗国”)内部互相争夺汗位,以及沙皇俄... 详细信息

“鄂尔齐”(oro i)有汗位继承人、储君和汗储等意思。俄文里的“намeстника”比较接近“鄂尔齐”一词的含义。“鄂尔齐”的出现与该制度的施行,跟土尔扈特汗国(国外文献一般称作“卡尔梅克汗国”)内部互相争夺汗位,以及沙皇俄国取得任命土尔扈特汗的权力有关。1724年9月,沙皇俄国任命策凌敦多卜为“卡尔梅克汗国汗鄂尔齐”。自此,沙皇俄国对土尔扈特施行“鄂尔齐”制度。研究“鄂尔齐”制度,对了解东归前土尔扈特社会内部问题和社会制度以及沙皇俄国统治土尔扈特的政治手段等有一定的学术价值,过去此问题没有被关注。本文主要利用托忒文档案,通过分析“鄂尔齐”制度出现的历史背景,考释“鄂尔齐”一词,探讨沙皇俄国任命土尔扈特首领为“汗鄂尔齐”称号的原因,考证土尔扈特东归时渥巴锡正式身份等问题。沙皇俄国对土尔扈特施行的“намeстника”制度,本文将其视为“鄂尔齐”制度。一、俄国对土尔扈特施行“鄂尔齐”制度的历史背景土尔扈特部在伏尔加河流域生活期间经历了七代、八位首领,分别是和鄂尔勒克、书库尔岱青、朋楚克、阿玉奇、策凌敦多卜、敦多克旺布、敦罗布喇什、渥巴锡。据《卡尔梅克诸汗简史》(以下简称《简史》)记载,a土尔扈特首领原来的称号是太师,书库尔岱青和阿玉奇被封汗之前也称太师。

关键词：土尔扈特部沙皇俄国渥巴锡卡尔梅克阿玉奇托忒文鄂尔勒克

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Aroma Properties of Selected Local Spices of Akwa Ibom State of Nigeria

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Journal of Agricultural Science and Technology(b) 2011年第7期1卷 989-997页

作者： e. U .U. Ituen A. F. Alonge Department of Agricultural and Food engineering University of Uyo Uyo 52003 Nigeria

Some famous local spices were selected to determine their potentials in terms of their aroma and utilization. They included Tea bush （Ocimum basilicum）, Guinea black Pepper （Piper guineense）, African Pepper （Xylopia aethiopica）, Alden Tree （Tetrapleura tetraptera） and the African Meg Nut or Onion Tree （blighia unijugata）. essential oils were extracted from the samples and used for aroma absorption test in a uv-visible spectrometer V2.03. The intensity of aroma was indicated at some peak values of absorption at particular wavelengths. The compounds responsible for the aroma at this peak values were identified by matching their wavelengths with those of known compounds at similar wavelengths of absorption. Thus, a compound such as Quinoline that has hot strong aroma and little bleaching effect was proved to be present in Guinea black pepper ;at the wavelength of 313.0 nm. benzene with hot strong aroma and flammable effect was also indicated in this spice at the wavelength of 253.0 rim. Proximate analysis carried out showed that these spices have high nutritive values. Some of them such as Guinea black pepper, African Nutmeg and ethiopian （African） pepper had high ether extract of 20.01, 25.97 and 31.25 respectively, and could be regarded as oil seeds, they contain much of essential oils.

关键词： Absorption wavelength aroma properties proximate analysis spice.

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evaluation of Cuban bacillus thuringiensis(berliner,1911)(bacillales:bacillacea)isolates with larvicidal activity against Aedes aegypti(Linnaeus,1762)(Diptera:Culicidae)

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Asian Pacific Journal of Tropical Medicine 2022年第2期15卷 79-86页

作者： Aileen Gonzalez Rizo Camilo e Castañet Martinez Celeste Ramírez Cardentey Ariamys Companioni Ibañez Zulema Menéndez Díaz Lianet Monzote Fidalgo Hilda M HernandezÁlvarez Vector Control Department Institute of Tropical MedicinePedro KouríAutopistaNovia del Mediodía km 6½La Habana 11400Cuba Virology Department Institute of Tropical MedicinePedro KouríAutopista Novia del Mediodía km 6½La Habana 11400Cuba Parasitology Department Institute of Tropical MedicinePedro KouríAutopista Novia del Mediodía km 6½La Habana 11400Cuba

Objective:To evaluate 11 Cuban native bacillus(b.)thuringiensis isolates in order to select one with the best larvicidal activity against Aedes(Ae.)aegypti and low ***:The cry and cyt genes of the isolates(A21,A51,L95,L910,M29,R84,R85,R87,R89,U81 and X48)were amplified by *** influence of organic matter and NaCl on the larvicidal activity was tested by *** was assayed on peritoneal macrophages of bALb/c ***:The cyt1(Aa,Ab,ba),cyt2,cry4aA,cry4ba,cry11(Aa,ba,bb)and cry10 genes were identified in all native Cuban *** larvicidal activity(LC_(90))of seven isolates was affected by the presence of organic matter in the water,while A21,A51,L910,R84,U81 and X48 had better LC_(50),LC_(90),LC_(95) than the 266/29-Ⅶ-98 control *** LC_(50) of two isolates was affected by the presence of NaCl and A21,A51,R85 isolate had better larvicidal activity than the 266/29-Ⅶ-98 control *** terms of toxicity against macrophages,the extracts of nine isolates were less cytotoxic than the control ***:Native isolate A21 had the main virulence factors against *** larvae,displayed a good larvicidal activity in presence of different factors related with *** breeding sites,and had low citotoxicity against *** results can contribute to the improvement of existing biological control strategies and the development of new biolarvicides.

关键词： Mosquitoes biological control agent bacillus thuringiensis bioassays Aedes aegypti cry and cyt genes

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