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Mechanical Behavior and Failure Mechanism of an As-Extruded Mg-11wt%Y Alloy at Elevated Temperature

Acta Metallurgica Sinica(English Letters) 2024年第6期37卷 969-981页

作者： Lan Zhang Dao-Kui Xu Bao-Jie wang Cui-Lan Lu Shuo wang Xiang-Bo Xu dong-liang wang Xin Lv En-Hou Han School of Materials Science and Engineering University of Science and Technology of ChinaShenyang110016China Key Laboratory of Nuclear Materials and Safety Assessment Institute of Metal ResearchChinese Academy of SciencesShenyang110016China School of Environmental and Chemical Engineering Shenyang Ligong UniversityShenyang110159China Key Lab of Electromagnetic Processing of Materials Ministry of EducationNortheastern UniversityShenyang110819China Institute of Corrosion Science and Technology Guangdong510070China

Through carrying out the high-temperature tensile experiments on an as-extruded Mg-11wt%Y alloy at 350℃,400℃,450℃,500℃and 550℃,the mechanical behavior and fracture mechanisms at elevated temperatures are investigated and *** results show that with the increase of temperature,the yield strength and ultimate tensile strength of the alloy increase at first and then decrease,while that the elongation ratio decreases firstly and then *** the sample being tested at 350℃,the values of yield strength,ultimate tensile strength and the elongation ratio are 188 MPa,266 MPa and 11%,*** 400℃,the yield strength and ultimate tensile strength reach the maximum values of,respectively,198 MPa and 277 MPa,but the elongation ratio is the lowest and its value is only 8%.When the applied temperature is increased to 550℃,the values of yield strength and ultimate tensile strength,respectively,decrease to 140 MPa and 192 MPa and the elongation ratio increases to 38%.Failure analysis demonstrates that the fracture surfaces of different samples are mainly composed of plastic dimples and exhibit the typical characteristic of ductile *** observation to the fracture side surfaces indicates that at the temperatures of 350℃and 400℃,microcracks mainly initiate in the interior of Mg_(24)Y_(5)*** the temperatures are 450℃,500℃and 550℃,the cracks preferentially initiate at the Mg_(24)Y_(5)/α-Mg interfaces.

关键词： Mg-Y alloy High-temperature tensile properties Fracture mechanism Failure analysis

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Comprehensive analysis of distal-less homeobox family gene expression in colon cancer

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World Journal of Gastrointestinal Oncology 2023年第6期15卷 1019-1035页

作者： Yong-Cheng Chen dong-Bing Li dong-liang wang Hui Peng Department of General Surgery(Endoscopic Surgery) The Sixth Affiliated HospitalSun Yat-sen UniversityGuangzhou 510655Guangdong ProvinceChina Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases The Sixth Affiliated HospitalSun Yat-sen UniversityGuangzhou 510655Guangdong ProvinceChina Biomedical Innovation Center The Sixth Affiliated HospitalSun Yat-sen UniversityGuangzhou 510655Guangdong ProvinceChina Department of Medicine ChosenMed Technology(Beijing)Co.Ltd.Beijing 100176China Department of General Surgery(Anorectal Surgery) The Sixth Affiliated HospitalSun Yat-sen UniversityGuangzhou 510655Guangdong ProvinceChina

BACKGROUND The distal-less homeobox(DLX)gene family plays an important role in the development of several ***,the expression pattern,prognostic and diagnostic value,possible regulatory mechanisms,and the relationship between DLX family genes and immune infiltration in colon cancer have not been systematically *** We aimed to comprehensively analyze the biological role of the DLX gene family in the pathogenesis of colon *** Colon cancer tissue and normal colon tissue samples were collected from the Cancer Genome Atlas and Gene Expression Omnibus *** rank sum test and t-test were used to assess DLX gene family expression between colon cancer tissue and unpaired normal colon *** was used to analyze DLX gene family variants.R software was used to analyze DLX gene expression in colon cancer and the relationship between DLX gene family expression and clinical features and correlation heat *** survival package and Cox regression module were used to assess the prognostic value of the DLX gene *** pROC package was used to analyze the diagnostic value of the DLX gene family.R software was used to analyze the possible regulatory mechanisms of DLX gene family members and related *** GSVA package was used to analyze the relationship between the DLX gene family and immune *** ggplot2,the survminer package,and the clusterProfiler package were used for *** DLX1/2/3/4/5 were significantly aberrantly expressed in colon cancer *** expression of DLX genes were associated with M stage,pathologic stage,primary therapy outcome,residual tumor,lymphatic invasion,T stage,N stage,age,perineural invasion,and history of colon ***5 was independently correlated with the prognosis of colon cancer in multivariate ***1/2/3/4/5/6 were involved in the development and progression of colon cancer by participating in immune infiltration and associated pathways,including the

关键词： Colon cancer The Cancer Genome Atlas Distal-less homeobox genes Prognosis Immune infiltration

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Endomembrane-biased dimerization of ABCG16 and ABCG25 transporters determines their substrate selectivity in ABA-regulated plant growth and stress responses

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Molecular Plant 2024年第3期17卷 478-495页

作者： Yeling Zhou Yuzhu wang dong Zhang Jiansheng liang institute of Plant and Food Science Department of BiologySchool of Life SciencesSouthern University of Science and Technology(SUSTech)Shenzhen 518055China Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes Southern University of Science and Technology(SUSTech)Shenzhen 518055China jiangsu Key Laboratory of Crop Genetics and Physiology/Co-lnnovation Center for Modern Production Technology of Grain Crops Key Laboratory of Plant Functional Genomics of the Ministry of EducationYangzhou UniversityYangzhou 225009China

ATP-binding cassette(ABC)transporters are integral membrane proteins that have evolved diverse func-tions fulfilled via the transport of various *** Arabidopsis,the G subfamily of ABC proteins is particularly abundant and participates in multiple signaling pathways during plant development and stress *** this study,we revealed that two Arabidopsis ABCG transporters,ABCG16 and ABCG25,engage in ABA-mediated stress responses and early plant growth through endomembrane-specific dimerization-coupled transport of ABA and ABA-glucosyl ester(ABA-GE),*** first revealed that ABCG16 contributes to osmotic stress tolerance via ABA *** specifically,ABCG16 induces cellular ABA efflux in both yeast and plant *** FRET analysis,we showed that ABCG16 forms oblig-atory homodimers for ABA export activity and that the plasma membrane-resident ABCG16 homodimers specifically respond to ABA,undergoing notable conformational ***,we demonstrated that ABCG16 heterodimerizes with ABCG25 at the endoplasmic reticulum(ER)membrane and facilitates the ER entry of ABA-GE in both Arabidopsis and tobacco *** specific responsiveness of the ABCG16-ABCG25 heterodimer to ABA-GE and the superior growth of their double mutant support an inhib-itory role of these twoABCGs in early seedling establishment via regulation of ABA-GE translocation across the ER *** endomembrane-specific analysis of the FRET signals derived from the homo-or heterodimerized ABcG complexes allowed us to link endomembrane-biased dimerization to the transloca-tion of distinct substrates by ABcG transporters,providing a prototypic framework for understanding the omnipotence of ABcG transporters in plant development and stress responses.

关键词： abscisic acid ABCG transporter dimerization endomembrane substrate selectivity

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Multiple Nanoparticles Coupling Strategy for Enhancing Optical Filter Performance of Spectral Splitter Used in Photovoltaic/Thermal System

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Journal of Thermal Science 2024年第1期33卷 368-382页

作者： liang Huaxu HUANG Xin wang Fuqiang CHENG Ziming dong Yan School of Energy Science and Engineering Harbin Institute of TechnologyHarbin 150001China School of New Energy Harbin Institute of Technology at WeihaiWeihai 264209China School of Materials Science and Engineering Nanyang Technological UniversitySingapore 639798Singapore

Selective absorptive nanofluid can pre-absorb certain sunlight wavelength that cannot be used by PV and transmits remaining sunlight to the surface of PV,which can decouple PV from the thermal receiver *** order to improve the harvesting of electricity and high-temperature thermal nanofluid,it is important to design an optimal optical filter window(transmit sunlight with wavelengths of 732-1067 nm to the surface of the photovoltaic cell and absorb the remaining sunlight).However,designing optimal optical filter is facing following challenges:(1) inherently narrow selective absorptivity property of single nanoparticle;(2) simplified numerical calculation method calculating transmittance;(3) ignoring the shape of the *** this study,the idea of using multiple nanoparticles coupling effect to design an optical filter is proposed,which can superimpose the narrow absorption bandwidth of different nanoparticles to obtain a wide absorption bandwidth of the whole *** addition,an improved transmission method considering light-matter interaction at air/vessel and liquid/vessel interfaces is adopted to compute the *** results calculated by improved transmission method are more accurate than widely used traditional Lambert-Beer law,which is verified by experimental ***,the effect of nanoparticle shape on spectral transmittance is also investigated,which shows that spiny Ag can approximately extend absorbance from 400 nm to 600 nm compared to nanosphere ***,the results show that optical filter efficiency of nanofluids with multiple nanoparticles coupling(Ag,spiny Ag,ZnO,ITO) can reached up to 35%.

关键词： solar energy PV/T nanofluid optimal optical filter radiative transfer spectral splitting

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Organic near-infrared optoelectronic materials and devices:an overview

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Advanced Photonics 2024年第1期6卷 17-42页

作者： Zong-Lu Che Chang-Cun Yan Xue-dong wang liang-Sheng Liao Soochow University Institute of Functional Nano and Soft Materials(FUNSOM)Jiangsu Key Laboratory for Carbon-Based Functional Materials and DevicesSuzhouChina Soochow University College of ChemistryChemical Engineering and Materials ScienceJiangsu Engineering Laboratory of Novel Functional Polymeric MaterialsSuzhouChina Macao University of Science and Technology Macao Institute of Materials Science and EngineeringMacaoChina

Near-infrared(NIR)light has shown great potential for military and civilian applications owing to its advantages in the composition of sunlight,invisibility to human eyes,deeper penetration into biological tissues,and low optical loss in optical ***,organic optoelectronic materials that can absorb or emit NIR light have aroused great scientific interest in basic science and practical *** on these NIR organic optoelectronic materials,NIR optoelectronic devices have been greatly improved in performance and *** this review,the representative NIR organic optoelectronic materials used in organic solar cells,organic photodetectors,organic light-emitting diodes,organic lasers,and organic optical waveguide devices are briefly introduced,and the potential applications of each kind of device are briefly ***,we summarize and take up the development of NIR organic optoelectronic materials and devices.

关键词： near-infrared organic optoelectronic materials organic solar cells organic light-emitting devices organic optical waveguides

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Theoretical and experimental investigations on single-atom catalysis:Pt1/FeOx for water-gas shift reaction Shan-Fei wang1,§,Yangyang Li2,3,§,Haiyan wang1,Jin-Xia liang1(✉),Chun Zhu1

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Nano Research 2024年第9期17卷 8627-8637页

作者： Shan-Fei wang Yangyang Li Haiyan wang Jin-Xia liang Chun Zhu Botao Qiao School of Chemistry and Chemical Engineering Guizhou UniversityGuiyang 550025China CAS Key Laboratory of Science and Technology on Applied Catalysis Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023China University of Chinese Academy of Sciences Beijing 100049China

Oxide-supported metal single-atom catalysts(SACs)have exhibited excellent catalytic performance for water-gas shift(WGS)***,we report the single-atom catalyst Pt1/FeOx exhibits excellent medium temperature catalytic performance for WGS reactions by the density functional theory(DFT)calculations and experimental *** calculations indicate that H_(2)O molecules are easily dissociated at oxygen vacancies,and the formed*OH and*O are adsorbed on Pt1 single atoms and the adjacent O atoms,*** studying four possible reaction mechanisms,it is found that the optimal WGS reaction pathway is proceeded along the carboxyl mechanism(pathway III),in which the formation of*COOH intermediates can promote the stability of Pt1/FeOx SAC and the easier occurrence of WGS *** energy barrier of the rate-determining step during the entire reaction cycle is only 1.16 eV,showing the high activity for the medium temperature WGS reaction on Pt1/FeOx SAC,which was verified by experimental ***,the calculated turnover frequencies(TOFs)of CO_(2)and H_(2)formation on Pt1/FeOx at 610 K(337℃)can reach up to 1.14×10^(-3)s^(-1)·site^(-1)through carboxyl *** this work,we further expand the application potential of Pt1/FeOx SAC in WGS reaction.

关键词： water-gas shift(WGS)reaction single-atom catalyst(SAC) density functional theory(DFT) thermocatalysis

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Three-dimensional stability calculation method for high and large composite slopes formed by mining stope and inner dump in adjacent open pits

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International Journal of Mining Science and Technology 2024年第4期34卷 507-520页

作者： Zuchao liang dong wang Guanghe Li Guangyu Sun Mingyu Yu dong Xia Chunjian Ding College of Mining Engineering Liaoning Technical UniversityFuxin 123000China Inner Mongolia Pingxi Baiyinhua Coal Industry Co. Ltd.Xilingol League 026000China Guoneng Baorixile Energy Co. Ltd.Hulunbuir 021008China

The 2D limit equilibrium method is widely used for slope stability ***,with the advancement of dump engineering,composite slopes often exhibit significant 3D mechanical ***,it is of significant importance to develop an effective 3D stability calculation method for composite slopes to enhance the design and stability control of open-pit slope *** the composite slope formed by the mining stope and inner dump in Baiyinhua No.1 and No.2 open-pit coal mine as a case study,this research investigates the failure mode of composite slopes and establishes spatial shape equations for the sliding *** integrating the shear resistance and sliding force of each row of microstrip columns onto the bottom surface of the strip corresponding to the main sliding surface,a novel 2D equivalent physical and mechanical parameters analysis method for the strips on the main sliding surface of 3D sliding masses is ***,a comprehensive 3D stability calculation method for composite slopes is developed,and the quantitative relationship between the coordinated development distance and its 3D stability coefficients is *** analysis reveals that the failure mode of the composite slope is characterized by cutting-bedding sliding,with the arc serving as the side interface and the weak layer as the bottom interface,while the destabilization mechanism primarily involves shear *** spatial form equation of the sliding mass comprises an ellipsoid and weak plane *** analysis revealed that when the coordinated development distance is 1500 m,the error rate between the 3D stability calculation result and the 2D stability calculation result of the composite slope is less than 8%,thereby verifying the proposed analytical method of equivalent physical and mechanical parameters and the 3D stability calculation method for composite ***,the3D stability coefficient of the composite slope exhibits an exponential co

关键词： Composite slope Destabilization mechanism 3D mechanical effect Three-dimensional stability Coordinated development distance

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Mechanical properties and acoustic emission characteristics of soft rock with different water contents under dynamic disturbance

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International Journal of Coal Science & Technology 2024年第3期11卷 135-148页

作者： Yujing Jiang Lugen Chen dong wang Hengjie Luan Guangchao Zhang Ling dong Bin liang State Key Laboratory of Mining Disaster Prevention and Control Co-Founded By Shandong Province and the Ministry of Science and Technology Shandong University of Science and TechnologyQingdao266590China State Key Laboratory for Geomechanics and Deep Underground Engineering China University of Mining and TechnologyBeijing100083China Inner Mongolia Shanghaimiao Mining Co. Ltd.Ordos016299China

Uniaxial compression tests and cyclic loading acoustic emission tests were conducted on 20%,40%,60%,80%,dry and saturated muddy sandstone by using a creep impact loading system to investigate the mechanical properties and acoustic emission characteristics of soft rocks with different water contents under dynamic *** mechanical properties and acoustic emission characteristics of muddy sandstones at different water contents were *** of experimental studies show that water is a key factor in the mechanical properties of rocks,softening them,increasing their porosity,reducing their brittleness and increasing their *** uniaxial compression,the macroscopic damage characteristics of the muddy sandstone change from mono-bevel shear damage and‘X’type conjugate bevel shear damage to a roadway bottom-drum type damage as the water content *** perturbation has a strengthening effect on the mechanical properties of samples with 60%and less water content,and a weakening effect on samples with 80%and more water content,but the weakening effect is not *** damage characteristics of dry samples remain unchanged,water samples from shear damage and tensile–shear composite damage gradually transformed into cleavage damage,until saturation transformation monoclinic shear *** evolution of acoustic emission energy and event number is mainly divided into four stages:loading stage(I),dynamic loading stage(II),yield failure stage(III),and post-peak stage(IV),the acoustic emission characteristics of the stages were different for different water *** characteristic value of acoustic emission key point frequency gradually decreases,and the damage degree of the specimen increases,corresponding to low water content—high main frequency—low damage and high water content—low main frequency—high damage.

关键词： Dynamic disturbance Soft rock Cyclic loading Acoustic emission Water content

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Recent advancement of sonogenetics:A promising noninvasive cellular manipulation by ultrasound

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Genes & Diseases 2024年第5期11卷 163-182页

作者： Jin Tang Mingxuan Feng dong wang liang Zhang Ke Yang Pediatric Research Institute Children’s Hospital of Chongqing Medical UniversityNational Clinical Research Center for Child Health and DisordersMinistry of Education Key Laboratory of Child Development and DisordersChina International Science and Technology Cooperation Base of Child Development and Critical DisordersChongqing Engineering Research Center of Stem Cell TherapyChongqing 400014China Department of Ultrasound The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Tongji Medical College Huazhong University of Science and TechnologyWuhanHubei 430074China

Recent advancements in biomedical research have underscored the importance of noninvasive cellular manipulation ***,a method that uses genetic engineering to produce ultrasound-sensitive proteins in target cells,is gaining prominence along with optogenetics,electrogenetics,and *** stimulation with ultrasound,these proteins trigger a cascade of cellular activities and *** traditional ultrasound modalities,sonogenetics offers enhanced spatial selectivity,improving precision and safety in disease *** technology broadens the scope of non-surgical interventions across a wide range of clinical research and therapeutic applications,including neuromodulation,oncologic treatments,stem cell therapy,and *** current literature predominantly emphasizes ultrasonic neuromodulation,this review offers a comprehensive exploration of *** discuss ultrasound properties,the specific ultrasound-sensitive proteins employed in sonogenetics,and the technique’s potential in managing conditions such as neurological disorders,cancer,and ophthalmic diseases,and in stem cell *** objective is to stimulate fresh perspectives for further research in this promising field.

关键词： Mechanosensitive channel Neuromodulation Sonogenetics Ultrasound Ultrasound-sensitive protein

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A semi-analytical model for coupled flow in stress-sensitive multi-scale shale reservoirs with fractal characteristics

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Petroleum Science 2024年第1期21卷 327-342页

作者： Qian Zhang Wen-dong wang Yu-liang Su Wei Chen Zheng-dong Lei Lei Li Yong-Mao Hao Key Laboratory of Unconventional Oil&Gas Development(China University of Petroleum(East China)) Ministry of EducationQingdao266580ShandongChina School of Petroleum Engineering China University of Petroleum(East China)Qingdao266580ShandongChina Shale Oil Development Branch Changqing Oilfield CompanyPetroChinaQingyang745708GansuChina PetroChina Research Institute of Petroleum Exploration&Development Beijing100083China

A large number of nanopores and complex fracture structures in shale reservoirs results in multi-scale flow of oil. With the development of shale oil reservoirs, the permeability of multi-scale media undergoes changes due to stress sensitivity, which plays a crucial role in controlling pressure propagation and oil flow. This paper proposes a multi-scale coupled flow mathematical model of matrix nanopores, induced fractures, and hydraulic fractures. In this model, the micro-scale effects of shale oil flow in fractal nanopores, fractal induced fracture network, and stress sensitivity of multi-scale media are considered. We solved the model iteratively using Pedrosa transform, semi-analytic Segmented Bessel function, Laplace transform. The results of this model exhibit good agreement with the numerical solution and field production data, confirming the high accuracy of the model. As well, the influence of stress sensitivity on permeability, pressure and production is analyzed. It is shown that the permeability and production decrease significantly when induced fractures are weakly supported. Closed induced fractures can inhibit interporosity flow in the stimulated reservoir volume (SRV). It has been shown in sensitivity analysis that hydraulic fractures are beneficial to early production, and induced fractures in SRV are beneficial to middle production. The model can characterize multi-scale flow characteristics of shale oil, providing theoretical guidance for rapid productivity evaluation.

关键词： Multi-scale coupled flow Stress sensitivity Shale oil Micro-scale effect Fractal theory

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