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Experimental study on dynamic mechanism of vortex evolution in a turbulent boundary layer of low Reynolds number

Journal of Hydrodynamics 2020年第5期32卷 807-819页

作者： Yan-ang Guo Xiang-rui dong Xiao-shu Cai Wu Zhou School of Energy and Power Engineering University of Shanghai for Science and TechnologyShanghai 200093China Key Laboratory of Multiphase Flow and Heat Transfer in Shanghai Power Engineering Shanghai 200093China

The dynamic mechanism of the vortex generation and evolution process in a fully developed turbulent boundary layer with Reθ=97-194 is experimentally *** this study,a moving single-frame and long-exposure(MSFLE)imaging method and a moving particle image velocimetry/particle tracing velocimetry(M-PIV/PTV)are designed and implemented for measuring the temporal and spatial evolution of vortex cores in both qualitative and quantitative ways,*** the other hand,the Liutex vector,which is a new mathematical definition and identification of the vortex core proposed by Liu’s group,is first applied in the experiment for the structural visualization and quantitative analysis of the local fluid *** results show that an intuitional process of vortex evolution can be clearly observed by tracking the vortex using MSFLE and verify that the roll-up of the shear layer induced by shear instability is the origin of vortex formation in ***,a quantitative investigation in terms of the critical vortex core boundary(size)and its accurate rotation strength is carried out based on the Liutex vector field analysis by M-PIV/*** to statistics of the relation between vortex core size and the rotation strength during the whole process,the physical mechanism of vortex generation and evolution in a turbulent boundary layer of low Reynolds number can be summarized as a four-dominant-state course consisting of the“synchronous linear segment(SL)-absolute enhancement segment(AE)-absolute diffusion segment(AD)-skewing dissipation segment(SD)”.

关键词： Turbulent boundary layer high-and low-speed fluid vortex generation moving single-frame and long-exposure moving particle image velocimetry/particle tracing velocimetry Liutex vector

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Effects of Sequence on Transmission Properties of DNA Molecules

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Communications in Theoretical Physics 2008年第8期50卷 532-536页

作者： dong rui-Xin YAN Xun-Ling YANG Bing School of Physical Science and Information Engineering Liaocheng University Lia~cheng 252059 China

A double helix model of charge transport in DNA molecule is given and the transmission spectra of four DNA sequences are *** calculated results show that the transmission characteristics of DNA are not only related to the longitudinal transport but also to the transverse transport of *** periodic sequence with the same composition has stronger conduction *** the increasing of bases composition,the conductive ability reduces,but the weight of θ direction rises in charge transfer.

关键词： DNA sequence dependence charge transport

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Effects of environmental humidity on the survival and development of pine caterpillars, Dendrolimus tabulaeformis （Lepidoptera： Lasiocampidae）

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Insect Science 2008年第2期15卷 147-152页

作者： rui-dong Han Megha Parajulee Zhong He Feng Ge State Key Laboratory of Integrated Management of Pest Insects and Rodents Institute of Zoology Chinese Academy of Sciences Beijing Weifang Forestry Bureau of Shandong Province Weifang City Shandong Province China Texas Agricultural Experiment Station Lubbock Texas USA

The pine caterpillar, Dendrolimus tabulaeformis is one of the most important pests on Pinus tabulaeformis and other pine species in North China. In the present study, effects of relative humidity （RH） on the development and survival of pine caterpillars and soil moisture （SM） on their diapausing larvae were investigated. Low RH （20%） deferred the development of eggs and larvae, reduced egg hatching and larval surviving compared to 40%, 60% and 80% RH. Both low （20%） and high （100%） RH reduced egg hatching, but only 20% RH deferred the development of larvae, prolonged developmental duration and reduced the body mass and body length of larvae. The SM influenced the survival of diapausing larvae significantly. The dry treatment significantly reduced the supercooling points （SCPs）, whereas increased the mortality and reduced body mass from 56.9 to 36.5 mg and body water content from 78% to 63% after 2 weeks＇ exposure. Therefore, higher RH is more favorable for the development of early instars and survival of diapausing larvae of the pine caterpillars.

关键词： cold hardiness Dendrolimus tabulaeformis development mortality relative humidit y

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Dynamic Properties of Proton Transfer in the Anharmonic-Interaction Hydrogen Bond Systems

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Communications in Theoretical Physics 2001年第5期35卷 615-620页

作者： Yan Xun-Ling dong rui-Xin Pang Xiao-Feng Department of Physics Liaocheng Teacher's College Liaocheng 252059 Shandong Province China Institute of High-Energy Electronics University of Electronic Science and Technology of China Chengdu 610054 China

We analyze the properties of the excited solitary-wave model in the case of anharmonic-interaction of heavy ionic lattice in hydrogen bond *** this case,some new phenomena *** find different types of solutions for the proton displacement and influences on the kinks and pulse solitary waves by numerical *** each of them we have presented a direct relation with the effective potential of the system.

关键词：氢原子束缚系统非简谐相互作用孤子波

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Therapeutic targets and biomarkers of tumor immunotherapy:response versus non-response

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Signal Transduction and Targeted Therapy 2022年第10期7卷 3784-3810页

作者： dong-rui Wang Xian-Lin Wu Ying-Li Sun Bone Marrow Transplantation Center The First Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhouChina Liangzhu Laboratory Zhejiang University Medical CenterHangzhouChina Institute of Hematology Zhejiang UniversityHangzhouChina Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy HangzhouChina Central Laboratory National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital&Shenzhen HospitalChinese Academic of Medical Sciences and Peking Union Medical CollegeShenzhenChina CAS Key Laboratory of Genomic Precision Medicine Beijing Institute of GenomicsChinese Academy of SciencesBeijingChina

Cancers are highly complex diseases that are characterized by not only the overgrowth of malignant cells but also an altered immune *** inhibition and reprogramming of the immune system play critical roles in tumor initiation and *** aims to reactivate antitumor immune cells and overcome the immune escape mechanisms of *** by immune checkpoint blockade and adoptive cell transfer,tumor immunotherapy has seen tremendous success in the clinic,with the capability to induce long-term regression of some tumors that are refractory to all other *** them,immune checkpoint blocking therapy,represented by PD-1/PD-L1 inhibitors(nivolumab)and CTLA-4 inhibitors(ipilimumab),has shown encouraging therapeutic effects in the treatment of various malignant tumors,such as non-small cell lung cancer(NSCLC)and *** addition,with the advent of CAR-T,CAR-M and other novel immunotherapy methods,immunotherapy has entered a new *** present,evidence indicates that the combination of multiple immunotherapy methods may be one way to improve the therapeutic ***,the overall clinical response rate of tumor immunotherapy still needs improvement,which warrants the development of novel therapeutic designs as well as the discovery of biomarkers that can guide the prescription of these *** from the past success and failure of both clinical and basic research is critical for the rational design of studies in the *** this article,we describe the efforts to manipulate the immune system against cancer and discuss different targets and cell types that can be exploited to promote the antitumor immune response.

关键词： immunotherapy prescription overcome

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Advances in the conventional clinical treatment for hepatoblastoma and therapeutic innovation

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World Journal of Pediatric Surgery 2021年第3期4卷 9-15页

作者： Zhixue Chen rui dong National Children's Medical Center Department of OncologyChildren's Hospital of Fudan UniversityShanghai Key Laboratory of Birth DefectsShanghaiChina

Background Hepatoblastoma(HB)is a rare malignancy usually occurring in children under 3 years *** advancements in surgical techniques and molecular biology,new treatments have been *** resources The recent literatures on new treatments,molecular mechanisms and clinical trials for HB were searched and *** Surgical resection remains the main option for treatment of *** complete resection is recommended,a resection with microscopical positive margins(R1)may have similar 5-year overall survival and 5-year event-free survival(EFS)rates after cisplatin chemotherapy and the control of metastasis,as only once described so *** green-guided surgery can help achieve precise ***,associating liver partition and portal vein ligation for staged hepatectomy can rapidly increase future liver remnant volume compared with portal vein ligation or ***-containing chemotherapies slightly differ among the guidelines from the International Childhood Liver Tumors Strategy Group(SIOPEL),Children’s Oncology Group(COG)and Chinese Anti-Cancer Association Pediatric Committee(CCCG),and the 3-year EFS rate of patients in SIOPEL and CCCG studies was recently shown to be higher than that in COG *** transplantation is an option for patients with unresectable HB,and successful cases of autologous liver transplantation have been *** addition,effective inhibitors of important targets,such as the mTOR(mammalian target of rapamycin)inhibitor rapamycin,β-catenin inhibitor celecoxib and EpCAM(epithelial cell adhesion molecule)inhibitor catumaxomab,have been demonstrated to reduce the activity of HB cells and to control metastasis in experimental research and clinical *** These advances in surgical and medical treatment provide better outcomes for children with HB,and identifying novel targets may lead to the development of future targeted therapies and immunotherapies.

关键词： clinical metastasis treatment

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Biliatresone:progress in biliary atresia study

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World Journal of Pediatrics 2023年第5期19卷 417-424页

作者： Jia‑Jie Zhu Yi‑Fan Yang rui dong Shan Zheng Department of Pediatric Surgery Shanghai Key Laboratory of Birth Defectand Key Laboratory of Neonatal DiseaseMinistry of HealthChildren’s Hospital of Fudan University399 Wan Yuan RoadShanghai 201102China

Background Biliary atresia(BA)is one of the main causes of neonatal end-stage liver *** timely diagnosis and treatment,most children with BA will develop irreversible liver fibrosis within the first two *** current theorized causes of BA include viral infection,immune disorders,and genetic defects,the comprehensive etiology is still largely ***,biliatresone attracted much interest for its ability to induce BA in both zebrafish and mice,so we summarized the latest progress of biliatresone research in BA and tried to answer the question of whether it could provide further clues to the etiology of human *** sources We conducted a PubMed search for any published articles related to the topic using search terms including“biliary atresia”,“biliatresone”,“GSH”,and“HSP90”.Relevant data were extracted from the original text or supplementary materials of the corresponding *** Biliatresone had shown its unique toxicity in multiple species such as zebrafish and mice,and pathogenic factors involved included glutathione(GSH),heat shock protein 90(HSP90)and the related *** combination with epidemiological evidence and recent studies on the intestinal flora in biliary atresia,a new pathogenic hypothesis that the occurrence of biliary atresia is partly due to biliatresone or its structure-like compounds depositing in human body via vegetables or/and the altered intestinal flora structure can be tentatively *** Based on the existing evidence,we emphasized that GSH and HSP90 are involved in the development of BA,and the maternal diet,especially higher vegetable intake of Asian women of childbearing age,accompanied by the altered intestinal flora structure,may contribute to the occurrence of biliary atresia and the higher incidence in the Asia ***,the evidence from large sample epidemiological research is necessary.

关键词： Biliary atresia Biliatresone Glutathione Gut flora

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INFLUENCE OF STRUCTURE ON HYDRAULIC CHARACTERISTICS OF T SHAPE FISHWAY

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Journal of Hydrodynamics 2012年第5期24卷 684-691页

作者： MAO Xi FU Jing-jing TUO You-cai AN rui-dong LI Jia State Key Laboratory of Hydraulics and Mountain River Engineering Sichuan University Chengdu 610065China HydroChina Hua dong Engineering Corp.9 Hangzhou 310014 China

While dams cut off the migratory route of fish, and affect their growth and breeding, fishways are built to restore the con- nectivity of rivers and facilitate the life cycle of these migratory fish. This paper proposes a new kind of fishway called the ＂T shape fishway＂, and studies it by using both numerical simulations and physical experimental methods with the aim to design a fishway in China for migratory fish with swimming and jumping capability much poorer, such as schizothorax davidi and schizothorax prenanti, as compared with migratory fish in other places of the world, like trout and salmon. It is indicated that the range of velocity in each regular pool of the T shape fishway is from 0.42 m/s to 1.22 m/s when the flow discharge Q is 350 L/s, and there are no large vortex zones found there. This study shows that the T shape fishway can meet the requirements of these migratory fish quite well in terms of velocity and flow patterns in China.

关键词： fishway migratory fish baffle drop sill numerical simulation experiment

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Effect of microstructure variation on corrosion properties of as-cast 0Cr23Ni13 stainless steel at high strain rate of hot compression

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Journal of Iron and Steel Research International 2023年第10期30卷 2091-2100页

作者： Jun-chen Li Meng-yuan Ye rui-dong Li Xing-run Chen School of Material Science and Engineering Lanzhou University of TechnologyLanzhou 730050GansuChina Xi'an Hantang Analysis and Testing Co. Ltd.Xi'an 710201ShaanxiChina Jiuquan Iron and Steel(Group)Co. Ltd.Jiayuguan 735100GansuChina

The optimization of hot compression technique of as-cast 0Cr23Ni13 stainless steel at high strain rate was discussed,and its corrosion resistance was evaluated after hot compression treatment *** adjusting the dynamic recrys-tallization(DRX)ratio of 0Cr23Nil3 stainless steel during hot pressing,the content of low Σ coincident site lattice(ΣCSL)grain boundaries is increased,and the grain orientation is *** results show that ferrite and austenite are completely recrystallized at 1050 and 1150℃,*** number of grains in theanddirections increases significantly,the corrosion potential increases,and the corrosion current density decreases,which will signifi-cantly improve the corrosion resistance of 0Cr23Nil3 stainless *** the optimization of grain boundary distribution,corrosion resistance is noticeably improved due to the existence of lowΣCSL *** interference effect of lowΣCSL grain boundary on random grain boundary network becomes intense with the increase in DRX ratio,which is the fundamental measure to improve the corrosion resistance.

关键词： OCr23Ni13 stainless steel Hot compression Dynamic recrystallization LowΣcoincident site lattice Corrosion resistance

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Role of CCUS in carbon neutral power system

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Carbon Neutrality 2022年第1期1卷 377-388页

作者： Yawen Zheng Lin Gao rui dong Song He Laboratory of Integrated Energy System and Renewable Energy Institute of Engineering ThermophysicsChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China North China Electric Power University Beijing 100096China

Achieving carbon neutrality by 2060 is an ambitious goal to promote the green transition of economy and society in *** relying on coal and contributing nearly half of CO_(2) emission,power industry is the key area for reaching carbon-neutral *** basis of carbon balance,a criterial equation of carbon neutral for power system is *** means of the equation,the different effects of three technical approaches to achieve carbon neutrality,including energy efficiency improvement,shifting energy structure and CO_(2) capture,utilization and storage(CCUS)technology,had been *** results indicate that building a carbon-neutral power system requires comprehensive coordination between energy efficiency,renewable energy and CCUS *** particular,the unique role of CCUS in achieving carbon neutral target was *** any power systems with fossil energy input,CCUS and negative emission technologies is indispensable to reach carbon ***,rather high energy consumption and costs is the critical gas deterring the large scale deployment of *** the specific conditions of China’s power industry,before the time window between 2030 and 2040 being closed,CCUS would either be ready for large scale deployment by reducing energy consumption and costs,or be phased out along with the most coal power ***,carbon neutral scenario will give CCUS the last chance to decarbonize the fossil fuel,which has great significance for China.

关键词： Carbon neutrality CCUS Power system Carbon emission intensity

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