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Post-translational Regulation of SPX Proteins for Coordinated Nutrient Signaling

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Molecular Plant 2019年第8期12卷 1041-1043页

作者： Yves poirier Department of Plant Molecular Biology University of Lausanne1015 LausanneSwitzerland

Proteins containing an SPX domain are involved in numerous aspects of phosphate homeostasis and the response to phosphate ***4 is known to bind to the transcription factor PHR2 in the presenee of inositol polyphosphate,affecting its ability to activate the expression of phosphate-starvation-induced (PSI) *** have evolved mechanisms to coordinate the uptake and utilization of phosphate and *** recent works (Hu et al.,2019;Ruan et al.,2019) have identified different E3 ubiquitin ligases that mediate the degradation of SPX4 under either phosphate-deficient conditions or nitrate-replete *** studies highlight the potential of SPX proteins,E3 ubiquitin ligases,and inositol polyphosphate to regulate distinet nutrient signaling pathways in a coordinated fashion.

关键词： Post-translational Regulation SPX Proteins Coordinated Nutrient Signaling phosphate-starvation-induced(PSI)

A taxonomy of built asset information coupling

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Frontiers of Engineering Management 2024年第2期11卷 247-268页

作者： Saman DAVARI Erik poirier Department of Construction Engineering Ecole de technologie superieureMontreal H3C 1K3Canada

The digital transformation of the built asset industry is moving toward closer integration of physical and digital assets and *** the framework of Cyber-Physical Systems(CPSs)and Digital Twins(DTs),an increasing number of studies focus on the technical aspects of CPS and ***,a unified framework describing the dimensions and characteristics essential for integrating lifecycle information remains *** leverage these concepts effectively,it is necessary to develop new frameworks to classify and put into relationship various components that comprise the lifecycle information integration of physical and digital assets and *** paper addresses these gaps by proposing a taxonomy of Built Asset Lifecycle Information Couples,which outlines the dimensions and characteristics crucial for the lifecycle information integration of built assets and *** proposed taxonomy contributes to the efforts aimed at organizing the knowledge domain of lifecycle information management in the built environment.

关键词： asset coupling taxonomy digitalization lifecycle information management built environment

Comment on"Reversible 3D optical data storage and information encryption in photo-modulated transparent glass medium"

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Light(Science & Applications) 2022年第8期11卷 1933-1934页

作者： Gael poirier Marcelo Nalin Sidney J.L Ribeiro Younes Messaddeq Institute of Science and Technology Federal University of AlfenasCampus Poços de CaldasPoços de CaldasMGBrazil Institute of Chemistry São Paulo State University UNESPAraraquaraSPBrazil

Dear Editor,The development of reversible photochromic materials combining efficient writing/erasing properties, low-cost and environmentally friendly compositions is a breakthrough challenge and a subject of many research works in the last decades. In this perspective, transparent oxide glasses are promising since their production is ensured by a simple melt-quenching technique and a proper laser writing setup is able to give rise to a localized photochromic effect, opening opportunities for 3D optical data storage.

关键词： transparent since glasses

Have some landscapes in the eastern Canadian boreal forest moved beyond their natural range of variability?

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Forest Ecosystems 2018年第4期5卷 412-428页

作者： Pierre Grondin Sylvie Gauthier Veronique poirier Patrice Tardif Yan Boucher Yves Bergeron Direction de la Recherche Forestiere Ministere des Foretsde la Faune et des Pares (MFFP)2700rue EinsteinQuebecQC GIP 3W8Canada Ressources Naturelles Canada/Natural Resources Canada Service Canadien des forets/Canadian Forest ServiceCentre de foresterie des Laurentides/Laurentian Forestry Center1055 rue du P.E.P.SQuebecQC G1V 4C7 Canada Institut de Recherche sur les Forets Universite du Quebec en Abitibi-Temiscamingue445boul.de I'UniversiteRouyn-NorandaQC J9X 5E4Canada Centre d'etude de la Foret Universite du QuebecMontreal CP 8888succ AMontrealQC H3C 3P8Canada

Background: In the contxt of ecosystem management, the present study aims to compare the natural and the present-day forested landscapes of a large territory in Quebec(Canada). Using contemporary and long-term fire cycles, each natural forst landscape is defined according to the variability of its structure and composition, and compared to the present-day landscape. This analysis was conducted to address the question of whether human activities have moved these ecosystems outside the range of natural landscape ***: The study encompassed a forested area of 175 000 km2 divided into 14 landscapes. Using a framework that integrates fire cycles, age structure and forest dynamics, we characterized the forest composition and age structures that resulted from three historical fire cycles(110,140, and 180 years) representative of the boreal forest of eastern Canada. The modeled natural landscapes were compared with present-day landscapes in regard to the proportion of old-growth forests(landscape level) and the proportion of late-successional forest stands(landscape level and potential vegetation type).Results: Four landscapes(39%) remain within their natural range of variability. In contrast, nine landscapes(54%)show a large gap between natural and present-day landscapes. These nine are located in the southern portion of the study area, and are mainly associated with Abies-Betula vegetation where human activities have contributed to a strong increase in the proportion of Populus tremuloides stands(early-successional stages) and a decrease of oldgrowth forest stands(more than 100 years old). A single landscape(7%), substantially changed from its potential natural state, is a candidate for adaptive-based ***: Comparison of corresponding natural(reference conditions) and present-day landscapes showed that ten landscapes reflecting an important shift in forest composition and age structure could be considered beyond the range of their natural v

关键词： Ecosystem management Reference conditions Natural variability Resilience Fire cycle Age structure Forest dynamics Potential vegetation type Landscape ecology Theoretical natural landscape Present-day landscape

Biomarkers of Human Exposure to Carcinogens: An Overview

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Biomedical and Environmental Sciences 1991年第1期4卷 69-72页

作者： FREDERICK A.BELAND MIRIAM C.poirier National Center for Toxicological Research JeffersonNational Cancer Institute Bethesda Arkansas 72079-9502 Maryland 20892

Environmental, occupational, or dietary exposure to certain chemicals has been shown to be associated with carcinogenesis in humans. In the 18th century, for example, Percival Pott (1775) noted a high incidence of scrotal cancer in chimney sweeps, which he attributed to their exposure to soot and a concomitant lack of bathing. Subsequent epidemiological studies have identified a number of additional carcinogenic agents, including aromatic amine-based dyes (Case et al., 1954), cigarette smoke (Wynder and Graham, 1950), asbestos (Doll, 1955), vinyl chloride (Creech and

关键词： An Overview Biomarkers of Human Exposure to Carcinogens

The first-line management of psychogenic non-epileptic seizures(PNES)in adults in the emergency:a practical approach

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Acta Epileptologica 2020年第1期2卷 48-58页

作者： Dènahin Hinnoutondji Toffa Laurence poirier Dang Khoa Nguyen Neurosciences Division Centre de Recherche du Centre Hospitalier de l’Universitéde Montréal900 Rue Saint-DenisMontreal(QC)H2X 0A9Canada. Neurology Department Centre Hospitalier de l’Universitéde MontréalMontrealQuebecCanada. Faculty of Medicine McGill UniversityMontrealCanada.

Distinguishing non-epileptic events,especially psychogenic non-epileptic seizures(PNES),from epileptic seizures(ES)constitutes a diagnostic *** are frequent,especially when video-EEG recording,the gold-standard for PNES confirmation,cannot be *** issue is further complicated in cases of combined PNES with *** emergency units,a misdiagnosis can lead to extreme antiepileptic drug escalade,unnecessary resuscitation measures(intubation,catheterization,etc.),as well as needless biologic and imaging *** of the acute window,an incorrect diagnosis can lead to prolonged hospitalization or increase of unhelpful antiepileptic drug *** recognition is thus desirable to initiate adequate treatment and improve *** experience-based strategies and a thorough review of the literature,we aimed to present the main clinical clues for physicians facing PNES in non-specialized units,before management is transferred to epileptologists and *** such conditions,patient recall or witness-report provide the first orientation for the diagnosis,recognizing that collected information may be *** analysis of an event(live or based on home-video)may lead to a clinical diagnosis of PNES with a high confidence ***,a fluctuating course,crying with gestures of frustration,pelvic thrusting,eye closure during the episode,and the absence of postictal confusion and/or amnesia are highly suggestive of ***,induction and/or inhibition tests of PNES have a good diagnostic value when *** may also be a useful biomarker to distinguish PNES from epileptic seizures,especially following bilateral tonic-clonic ***,regardless the level of certainty in the diagnosis of the PNES,it is important to subsequently refer the patient for epileptological and neuropsychiatric follow-up.

关键词： Psychogenic non-epileptic seizures(PNES) Epilepsy Emergency Pseudostatus Prolactin dosage Homemade video

Biomarkers of Human Exposure to Carcinogens: An Overview

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Biomedical and Environmental Sciences 1991年第Z1期 69-72页

作者： FREDERICK A.BELAND,MIRIAM C.poirier National Center for Toxicological Research Jefferson National Cancer Institute Bethesda Arkansas 72079-9502 Maryland 20892

关键词： An Overview Biomarkers of Human Exposure to Carcinogens

Regulation of Phosphate Starvation Responses in Plants： Signaling Players and Cross-Talks

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Molecular Plant 2010年第2期3卷 288-299页

作者： Hatem Rouached A. Bulak Arpat Yves poirier Department of Plant Molecular Biology University of Lausanne CH-1015 Lausanne Switzerland

Phosphate （Pi） availability is a major factor limiting growth, development, and productivity of plants. In both ecological and agricultural contexts, plants often grow in soils with low soluble phosphate content. Plants respond to this situation by a series of developmental and metabolic adaptations that are aimed at increasing the acquisition of this vital nutrient from the soil, as well as to sustain plant growth and survival. The development of a comprehensive understanding of how plants sense phosphate deficiency and coordinate the responses via signaling pathways has become of major interest, and a number of signaling players and networks have begun to surface for the regulation of the phosphate- deficiency response. In practice, application of such knowledge to improve plant Pi nutrition is hindered by complex cross-talks, which are emerging in the face of new data, such as the coordination of the phosphate-deficiency signaling networks with those involved with hormones, photo-assimilates （sugar）, as well as with the homeostasis of other ions, such as iron. In this review, we focus on these cross-talks and on recent progress in discovering new signaling players involved in the Pi-starvation responses, such as proteins having SPX domains.

关键词： Phosphate signaling SPX iron phytohormones.

Using <i>ScalIT</i>for Performing Accurate Rovibrational Spectroscopy Calculations for Triatomic Molecules: A Practical Guide

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Applied Mathematics 2014年第17期5卷 2756-2763页

作者： Corey Petty Bill poirier Department of Chemistry and Biochemistry Texas Tech University Lubbock Texas USA

This paper presents a practical guide for use of the ScalIT software package to perform highly accurate bound rovibrational spectroscopy calculations for triatomic molecules. At its core, ScalIT serves as a massively scalable iterative sparse matrix solver, while assisting modules serve to create rovibrational Hamiltonian matrices, and analyze computed energy levels (eigenvalues) and wavefunctions (eigenvectors). Some of the methods incorporated into the package include: phase space optimized discrete variable representation, preconditioned inexact spectral transform, and optimal separable basis preconditioning. ScalIT has previously been implemented successfully for a wide range of chemical applications, allowing even the most state-of-the-art calculations to be computed with relative ease, across a large number of computational cores, in a short amount of time.

关键词： Rovibrational Spectroscopy Iterative Matrix Solver Lanczos Quasiminimal Residual Molecular Bound States HO2