Biomarkers of Human Exposure to Carcinogens: An Overview
作者机构：National Center for Toxicological Research Jefferson National Cancer Institute Bethesda Arkansas 72079-9502 Maryland 20892
出 版 物：《Biomedical and Environmental Sciences》 (生物医学与环境科学(英文版))
年 卷 期：1991年第Z1期
页 面：69-72页
核心收录：
主 题：An Overview Biomarkers of Human Exposure to Carcinogens
摘 要：Environmental, occupational, or dietary exposure to certain chemicals has been shown to be associated with carcinogenesis in humans. In the 18th century, for example, Percival Pott (1775) noted a high incidence of scrotal cancer in chimney sweeps, which he attributed to their exposure to soot and a concomitant lack of bathing. Subsequent epidemiological studies have identified a number of additional carcinogenic agents, including aromatic amine-based dyes (Case et al., 1954), cigarette smoke (Wynder and Graham, 1950), asbestos (Doll, 1955), vinyl chloride (Creech and
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