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Cooling of Hyperonic Neutron Stars with Antikaons

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Chinese Physics Letters 2011年第7期28卷 85-88页

作者： ding wen-bo YU Zi LIU Yu-Hui School of Mathematics and Physics Bohai UniversityJinzhou 121000 College of Science Nanjing Forestry UniversityNanjing 210037

We discuss the impact of hyperons on the neutrino emitting and the gross cooling features of neutron stars with K−and K0 *** results show that hyperons change the density ranges of the direct Urca process with nucleons and the Urca processes of K−and K0 condensations,as well as the values of neutrino ***,interactions between hyperons and antikaons make the neutrino luminosity *** is found that various hyperons play different roles in neutron *** massive stars,Σhyperons make the cooling ***,Λcan hardly change the cooling history but it reduces the mass of neutron stars.

关键词： condensation slower stars

PSR J1614-2230 May Include Hyperons

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Chinese Physics Letters 2011年第8期28卷 352-355页

作者： YU Zi ding wen-bo BAO Tmurbagan LIU Ning-Ning The College of Science Nanjing Forestry UniversityNanjing 210037 Department of Physics Bohai UniversityJinzhou 121000 College of Physics and Electronic Engineering Nanyang Normal UniversityNanyang 473061 Department of Basic Course Nanjing Institute of TechnologyNanjing 211167

In the framework of the relativistic mean field theory,it is found that recently discovered PSR J1614-2230 with mass of 1.97±0.04Mʘmay include hyperons when the weakly interacting light boson(WILB)is *** describe PSR J1614−2230 with the equation of state(EOS)including hyperons,the characteristic scale of the WILB(g^(2)/μ^(2))should lie in the range of 13–46(24–46)GeV^(−2) with the weak(strong)hyperon-hyperon(YY)*** measurements of inertial momentum and the total neutrino luminosity of the neutron star could be used to further constrain the characteristic scale of the *** more stringent constraint on the WILB is given,the mass measurement of the neutron star could not exclude any soft EOS.

关键词： interaction weakly momentum

Influence of σ^(* )and φ Mesons on (A) Hyperon ^(1)S_(0) Superfluidity in Neutron Star Matter

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Chinese Physics Letters 2012年第5期29卷 252-255页

作者： XU Yan LIU Guang-Zhou WANG Hong-Yan ding wen-bo ZHAO En-Guang Changchun Observatory National Astronomical ObservatoriesChinese Academy of SciencesChangchun 130117 Center for Theoretical Physics Jilin UniversityChangchun 130012 Department of Physics Bohai UniversityJinzhou 121000 Institute of Theoretical Physics Chinese Academy of SciencesBeijing 100190

Within the framework of the relativistic mean field theory,we investigate the ^(1)S_(0) superfluidity (SF) of A hyperons in neutron star (NS) matter including σ^(*) and φ *** energy gap of ∧ hyperons is calculated with the Nijmegen one-boson-exchange potentials for a (∧∧) pair. The parameter set we use is in line with the recent experimental data △B_(∧∧) ~ 1.01 ± 0.20_+0.18-0.11 *** is found that with σ^(*) and φ mesons the pairing energy gap △F of ∧ hyperons and the corresponding SF critical temperature T_(C∧) are *** addition the NS mass range of ∧ hyperon SF is enlarged obviously.

关键词： meson relativistic addition

Controlling and decision-making based on All Set Theory

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通讯和计算机（中英文版） 2007年第8期4卷 6-10页

作者： ding wen-bo HE Zhong-xiong Beijing Jiaotong University Beijing 100044 China

From Babel No More to Second Language Teaching

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海外英语 2017年第1期 229-232页

作者：丁伯文 Anqing Normal University

Nowadays, there are many super language learners speaking more than ten languages, some of whom are introduced by Michael Erard in the book Babel No More. After reading the book and researching some young hyperpolyglots from the internet, people can find out that what is knowing a language and the different language learning strategies from these super language learners. With critically analyzing each hyperpolyglot, we can apply these strategies to the area of second language *** words:

关键词： language learner hyperpolyglot second language teaching

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通过汶川地震看如何提高我国紧急医疗救援能力

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中国全科医学 2011年第20期14卷 2335-2337页

作者：丁文博湖北省武汉市急救中心 430021

通过研究汶川地震中绵竹市等地应急医疗救援信息与数据,比较救援效果,得到这样的提示:专业化的灾害医疗救援队在灾害医疗救援中起到了重要作用,成立我国地区性的专业化灾害医疗救援队,重视相关人员的培训和救援物资的储备是提高我国医... 详细信息

通过研究汶川地震中绵竹市等地应急医疗救援信息与数据,比较救援效果,得到这样的提示:专业化的灾害医疗救援队在灾害医疗救援中起到了重要作用,成立我国地区性的专业化灾害医疗救援队,重视相关人员的培训和救援物资的储备是提高我国医疗救援水平和效率的重要举措。

关键词：自然灾害救援作业

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Deciphering fungal metabolon coupling tandem inverse-electrondemand Diels-Alder reaction and semipinacol rearrangement for the biosynthesis of spiro polycyclic alkaloids

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Science China Chemistry 2025年第1期68卷 288-296页

作者： Shuai Liu wen-Qiang Xu Ying-Tong Di Man-Cheng Tang ding-Kang Chen Ming-Ming Cao Yao-wen Chang Hong-Yu Tang Chun-Mao Yuan Jun-bo Yang Zhi-Li Zuo Han Guo Zi-Fei Xu Ying Zeng Yun-Dong Wu Xiao-Jiang Hao Key Laboratory of Phytochemistry and Natural Medicines (Chinese Academy of Sciences) Kunming Institute of Botany Chinese Academy of Sciences University of Chinese Academy of Sciences Lab of Computational Chemistry and Drug Design State Key Laboratory of Chemical Oncogenomics Peking University Shenzhen Graduate School Shenzhen Bay Laboratory State Key Laboratory of Microbial Metabolism School of Life Sciences & Biotechnology Shanghai Jiao Tong University State Key Laboratory of Functions and Applications of Medicinal Plants Guizhou Medical University Molecular Biology Experimental Center Germplasm Bank of Wild Species in Southwest China Kunming Institute of Botany Chinese Academy of Sciences Yunnan Key Laboratory for Wild Plant Resources Kunming Institute of Botany Chinese Academy of Sciences Research Unit of Chemical Biology of Natural Anti-Virus Products Chinese Academy of Medical Sciences

In the intricate process of natural product biosynthesis, a metabolon can enhance metabolic flux by associating sequential enzymes. A fungal metabolon, comprising of flavin-dependent monooxygenase Spe F and P450 monooxygenase Spe G, is identified in the biosynthesis of spiro polycyclic alkaloids(+)-notoamide B and its diastereomer(+)-versicolamide B. Using notoamide E as a substance, Spe F/Spe G metabolon can control the stereoselectivity of its 2,3-epoxidation, followed by hydrogen atom ion at C-17 to generate reactive epoxide tau-m A with dienyl iminium unit. Subsequently,(+)-notoamide B and(+)-versicolamide B are produced via tandem nonenzymatic inverse-electron-demand Diels-Alder reaction and semipinacol rearrangement. This provides the first example of metabolon in the biosynthesis of spiro-prenylated indole alkaloids.

关键词： metabolon Diels-Alder reaction semipinacol rearrangement biosynthesis notoamides spiro polycyclic alkaloids

Deciphering the role of mtH2O2 in hepatic ischemia-reperfusion injury mechanisms with low-background super-resolution fluorogenic probe

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Science China Chemistry 2025年第1期68卷 297-307页

作者： Bin Fang Limin Wang Haoqin Li Jiaxin Zhang Yang ding Pan Pan Li bo Peng Hua Bai Lin Li Frontiers Science Center for Flexible Electronics Xi'an Institute of Flexible Electronics (IFE) and Xi'an Institute of Biomedical Materials &Engineering Northwestern Polytechnical University Institute of Flexible Electronics (IFE Future Technologies) Xiamen University

Hepatic ischemia-reperfusion injury（HIRI） is characterized by mitochondrial dysfunction and oxidative stress. Monitoring mitochondrial hydrogen peroxide（mtH2O2） levels in real-time through super-resolution imaging is crucial for elucidating its distribution in live cells and its mechanism of action during HIRI. However, low-background fluorogenic probes have been overlooked in the context of super-resolution imaging. In this study, we developed a low-background fluorogenic probe（MitoWG） with the potential for super-resolution morphology-correlated mitochondrial identification to track the fluctuates of mtH2O2in HIRI. Activation of the desirable fluorescence properties of the probe by mtH2O2was confirmed using structural illumination microscopy（SIM）, enabling high-quality mitochondrial imaging with exceptional specificity and *** in mtH2O2levels were successfully observed in both cellular and rat models of HIRI. Furthermore, we associated the decline in mitochondrial redox homeostasis with accelerated mtH2O2production during HIRI, which triggered mitophagy deficiency and led to cell death. In conclusion, Mito-WG possesses excellent photophysical and low-background properties for SIM imaging, making it a promising tool for mtH2O2tracking in HIRI research and clinical diagnosis.

关键词： hepatic ischemia-reperfusion injury low-background mtH2O2-activatable super-resolution imaging fluorogenic probe

PI3K/AKT signaling and neuroprotection in ischemic stroke:molecular mechanisms and therapeutic perspectives

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Neural Regeneration Research 2025年第10期20卷 2758-2775页

作者： Tianlong Liu Xiaolin Li Xiaowei Zhou Wei Chen Aidong wen Minna Liu Yi ding Department of Pharmacy Xijing HospitalFourth Military Medical UniversityXi’anShaanxi ProvinceChina Department of Pharmacy The 940 Hospital of Joint Logistics Support Forces of Chinese PLALanzhouGansu ProvinceChina Department of Pharmacy The 944 Hospital of Joint Logistics Support Forces of Chinese PLAJiuquanGansu ProvinceChina Department of Nephrology The 940 Hospital of Joint Logistics Support Forces of Chinese PLALanzhouGansu ProvinceChina

It has been reported that the PI3K/AKT signaling pathway plays a key role in the pathogenesis of ischemic *** a result,the development of drugs targeting the PI3K/AKT signaling pathway has attracted increasing attention from *** article reviews the pathological mechanisms and advancements in research related to the signaling pathways in ischemic stroke,with a focus on the PI3K/AKT signaling *** key findings include the following:(1)The complex pathological mechanisms of ischemic stroke can be categorized into five major types:excitatory amino acid toxicity,Ca^(2+)overload,inflammatory response,oxidative stress,and apoptosis.(2)The PI3K/AKT-mediated signaling pathway is closely associated with the occurrence and progression of ischemic stroke,which primarily involves the NF-κB,NRF2,BCL-2,mTOR,and endothelial NOS signaling pathways.(3)Natural products,including flavonoids,quinones,alkaloids,phenylpropanoids,phenols,terpenoids,and iridoids,show great potential as candidate substances for the development of innovative anti-stroke medications.(4)Recently,novel therapeutic techniques,such as electroacupuncture and mesenchymal stem cell therapy,have demonstrated the potential to improve stroke outcomes by activating the PI3K/AKT signaling pathway,providing new possibilities for the treatment and rehabilitation of patients with ischemic *** investigations should focus on the direct regulatory mechanisms of drugs targeting the PI3K/AKT signaling pathway and their clinical translation to develop innovative treatment strategies for ischemic stroke.

关键词： apoptosis autophagy inflammation ischemic stroke neuroprotection oxidative stress pathogenesis phosphatidylinositol 3-kinase protein kinase B therapeutics

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