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NUMERICAL SOLUTION OF THE NAVIER-STOKES EQUATIONS FOR 3-D REGION USING BODY-FITTED COORdiNATE SYSTEM

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Journal of Hydrodynamics 1991年第3期3卷 105-109页

作者： Jie-min, Zhan di-ming, zhang Shongskan Univ Guangzhou China

A three-dimensional method is presented for the three dimensional Navier-Stokes equations using body-fitted coordinate system. For the convenience of generating the coordinate system, we give some slip-coordinate boundary conditions. Numerical results for driven flow in a polar cavity show excellent agreement with the experimental study given by L. Fuchs and N. Tillmark.

关键词： Computers Applications Fluid Mechanics Mathematical Models

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肥胖对眼部相关疾病影响的研究进展

国际眼科杂志 2025年第1期25卷 88-93页

作者：张菂王慧娴张旭李文静新疆医科大学新疆维吾尔自治区乌鲁木齐市830011 新疆四七四医院眼科新疆维吾尔自治区乌鲁木齐市830011

肥胖是多种慢性非传染性疾病的危险因素和病理基础,是导致人类致死和致残的重要危险因素。肥胖对身体的危害不仅包括各种全身疾病,还有部分眼部相关疾病。目前人们对生活及视觉质量的更高追求,使眼部疾病的病因和预防研究受到了更多关注... 详细信息

肥胖是多种慢性非传染性疾病的危险因素和病理基础,是导致人类致死和致残的重要危险因素。肥胖对身体的危害不仅包括各种全身疾病,还有部分眼部相关疾病。目前人们对生活及视觉质量的更高追求,使眼部疾病的病因和预防研究受到了更多关注,肥胖对眼部疾病的影响也逐渐被发现。文章就肥胖对部分眼部相关疾病的影响进行综述,以期加深肥胖对眼部相关疾病影响的认识,并为眼部疾病防治提供参考。

关键词：肥胖干眼白内障青光眼视网膜疾病屈光不正

Interface-dominated mechanical behavior in advanced metal matrix composites

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Nano Materials Science 2020年第1期2卷 66-71页

作者： Qiang Guo Yifan Han di zhang State Key Lab of Metal Matrix Composites Shanghai Jiao Tong University800 Dongchuan RoadShanghai200240China

Metal matrix composites(MMCs)incorporate a reinforcing or functional secondary phase into a metal matrix to achieve specific *** the parameters which may affect the mechanical behavior of MMCs,the structure and properties of the reinforcement/matrix interface play a crucial *** article reviews recent developments in measuring the interfacial properties in advanced MMCs,with an emphasis on the use of micro-/nano-mechanical testing *** is shown that,with the novel in situ and ex situ experimental capability,researchers can now obtain some of the critical interfacial properties as well as the effects of reinforcement/matrix interfaces on the composites’deformation and failure mechanisms that were unattainable previously by conventional ***,the micro-/nano-mechanical testing platform allows for both fundamental and applied research on the composites’mechanical performance under service conditions,which is considered a promising and emerging research direction.

关键词： Metal matrix composites Interface Mechanical behavior Nanostructure Strengthening

The influence of slope collapse on water exchange between a pit lake and a heterogeneous aquifer

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Frontiers of Environmental Science & Engineering 2019年第2期13卷 63-71页

作者： Bo zhang Xilai Zheng Tianyuan Zheng Jia Xin Shuai Sui di zhang Shandong Provincial Key Laboratory of Marine Environment and Geological Engineering Ocean University of ChinaQingdao 266100China Key Laboratory of Marine Environmental Science and Ecology (Ministry of Education) College of Environmental Science and EngineeringOcean University of ChinaQingdao 266100China Department of Environmental Informatics Helmholtz Centre for Environmental Research-UFZLeipzig 04318Germany Key Laboratory of Surficial Geochemistry Ministry of EducationDepartment of HydrosciencesSchool of Earth Sciences and EngineeringNanjing UniversityNanjing 210023China College of Engineering Ocean University of ChinaQingdao 266100China

Due to the increase in open pit mining,pit lakes have become common surface water features,posing a potential risk to subsurface *** this study,a pit lake–groundwater interaction model is built based on the general program MODFLOW with the LAK3 *** the first time,the effects of lake-slope collapse and aquifer heterogeneity on pit lake–groundwater interactions are analyzed by dividing the lake into six water exchange zones based on the aquifer lithology and groundwater *** investigation and simulations reveal a total water exchange from groundwater to the lake of 349000 m3/a without collapse of the pit lake slope,while the total net water exchange under slope collapse conditions is 248000 m3/a(i.e.,a reduction of 1.40-fold).The monthly net water exchange per unit width from groundwater to the lake reaches the largest in April,shifting to negative values in zone IV from June to August and in zone V in June and ***,the monthly net water exchange per unit width decreases from north to south,and the direction and magnitude of water exchange are found to depend on the hydraulic gradients between the lake and groundwater and the hydraulic conductivity of the slope collapse.

关键词： Pit lak Slope collapse Groundwater-surface water interactions Numerical simulation

Laccase immobilized on magnetic nanoparticles by dopamine polymerization for 4-chlorophenol removal

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Green Energy & Environment 2017年第4期2卷 393-400页

作者： di zhang Manfeng Deng Hongbin Cao Songping zhang He Zhao Beijing Engineering Research Center of Process Pollution Control Division of Environment Technology and Engineering Institute of Process EngineeringChinese Academy of Sciences Collaborative Innovation Center of Chemical Science and Engineering State Key Laboratory of Biochemical Engineering Institute of Process Engineering Chinese Academy of Sciences

In this work, a new immobilization method based on dopamine(DA) self-polymerization was developed for laccase immobilization on magnetic nanoparticles(Fe_3O_4 NPs). To optimize the immobilization condition including reaction pH, DA concentration and enzyme concentration, a central composite response surface method was applied. The optimal condition was determined as p H value of 5.92, laccase concentration of 0.25 mg mL^(-1) and DA concentration of 12.74 mg mL^(-1), under which a high enzyme activity recovery of 88.17% was *** comparing with free laccase, the stabilities of immobilized laccase towards p H, thermostability, storage were enhanced *** 60% of relative activity for immobilized laccase was remained after being incubated for 6 h at 50℃, but the free laccase only remained 25%. After 40 days of storage at 4℃, the laccase immobilized by DA kept about 89% of its original activity, but the free laccase only retained 48%. After recycled 10 times, the relative activity of immobilized laccase still retained 70%. The immobilized laccase was then applied to catalyze the degradation of 4-chlorophenol(4-CP), 86% percentage of 4-CP was removed within 2 h. After degraded 10 times, the relative activity of immobilized laccase still remained 64% of its initial activity, which exhibits an excellent reusability and operational stability.

关键词： Magnetic nanoparticle Laccase Dopamine Immobilization 4-Chlorophenol removal

Current status of in vivo bioanalysis of nano drug delivery systems

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Journal of Pharmaceutical Analysis 2020年第3期10卷 221-232页

作者： Tingting Wang di zhang Dong Sun Jingkai Gu Clinical Laboratory The First HospitalJilin UniversityChangchun130061PR China Research Institute of Translational Medicine The First HospitalJilin UniversityChangchun130061PR China Research Center for Drug Metabolism College of Life ScienceJilin UniversityChangchun130012PR China Department of Biopharmacy College of Life ScienceJilin UniversityChangchun130012PR China Key Laboratory of Molecular Pharmacology and Drug Evaluation Ministry of EducationYantai UniversityYantai264005PR China

The development of nano drug delivery systems(NDDSs)provides new approaches to fighting against *** NDDSs are specially designed to serve as carriers for the delivery of active pharmaceutical ingredients(APIs)to their target sites,which would certainly extend the benefit of their unique physicochemical characteristics,such as prolonged circulation time,improved targeting and avoiding of *** the remarkable progress achieved over the last three decades,the understanding of the relationships between the in vivo pharmacokinetics of NDDSs and their safety profiles is *** of NDDSs is far more complicated than the monitoring of small molecular drugs in terms of structure,composition and aggregation state,whereby almost all of the conventional techniques are inadequate for accurate profiling their pharmacokinetic behavior in ***,the advanced bioanalysis for tracing the in vivo fate of NDDSs is summarized,including liquid chromatography tandemmass spectrometry(LC-MS/MS),Forster resonance energy transfer(FRET),aggregation-caused quenching(ACQ)fluorophore,aggregation-induced emission(AIE)fluorophores,enzyme-linked immunosorbent assay(ELISA),magnetic resonance imaging(MRI),radiolabeling,fluorescence spectroscopy,laser ablation inductively coupled plasma MS(LA-ICP-MS),and size-exclusion chromatography(SEC).Based on these technologies,a comprehensive survey of monitoring the dynamic changes of NDDSs in structure,composition and existing form in system(*** polymers,released and encapsulated drug)with recent progress is *** hope that this review will be helpful in appropriate application methodology for investigating the pharmacokinetics and evaluating the efficacy and safety profiles of NDDSs.

关键词： NDDSs Polymer Methodology Pharmacokinetics Release

disinfection byproducts in indoor swimming pool water: Detection and human lifetime health risk assessment

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Journal of Environmental Sciences 2023年第4期126卷 378-386页

作者： di zhang Shengkun Dong Li Chen Rong Xiao Wenhai Chu State Key Laboratory of Pollution Control and Resources Reuse College of Environmental Science and EngineeringTongji UniversityShanghai 200092China Shanghai Institute of Pollution Control and Ecological Security Shanghai 200092China Southern Laboratory of Ocean Science and Engineering Key Laboratory of Water Cycle and Water Security in Southern China of Guangdong Higher Education InstituteSun Yat-sen UniversityGuangzhou 510275China

Quantification of regulated and emerging disinfection byproducts (DBPs) in swimming pool water,as well as the assessment of their lifetime health risk are limited in *** this study,the occurrence of regulated DBPs (e.g.,trihalomethanes,haloacetic acids) and emerging DBPs (e.g.,haloacetonitriles,haloacetaldehydes) in indoor swimming pool water and the corresponding source water at a city in Eastern China were *** concentrations of DBPs in swimming pool water were 1-2 orders of magnitude higher than that in source *** cancer and non-cancer risks of DBPs stemming from swimming pool water were also *** and dermal exposure were the most significant exposure routes related to swimming pool DBP cancer and non-cancer *** the first time,buccal and aural exposure were considered,and were proven to be important routes of DBP exposure (accounting for 17.9%-38.9%of total risk).The cancer risks of DBPs for all swimmers were higher than 10^(-6)of lifetime exposure risk recommended by United States Environmental Protection Agency,and the competitive adult swimmers experienced the highest cancer risk (7.82×10^(-5)).These findings provide important information and perspectives for future efforts to lower the health risks associated with exposure to DBPs in swimming pool water.

关键词： Health risk assessment Swimming pool water disinfection byproducts Multiple exposure pathway

Machine learning powered ellipsometry

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Light(Science & Applications) 2021年第4期10卷 582-588页

作者： Jinchao Liu di zhang dianqiang Yu Mengxin Ren Jingjun Xu The Key Laboratory of Weak-Light Nonlinear Photonics Ministry of EducationSchool of Physics and TEDA Applied Physics InstituteNankai UniversityTianjin 300071China College of Artificial Intelligence Nankai UniversityTianjin 300071China Collabo rative Innovation Center of Extreme Optics Shanxi UniversityTaiyuanShanxi 030006China

Ellipsometry is a powerful method for determining both the optical constants and thickness of thin *** decades,solutions to ill-posed inverse ellipsometric problems require substantial human-expert intervention and have become essentially human-in-the-loop trial-and-error processes that are not only tedious and time-consuming but also limit the applicability of ***,we demonstrate a machine learning based approach for solving ellipsometric problems in an unambiguous and fully automatic manner while showing superior *** proposed approach is experimentally validated by using a broad range of films covering categories of metals,semiconductors,and *** method is compatible with existing ellipsometers and paves the way for realizing the automatic,rapid,high-throughput optical characterization of films.

关键词： consuming inverse essentially

The hydraulic performance of twin-screw pump

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Journal of Hydrodynamics 2020年第3期32卷 605-615页

作者： di zhang Li Cheng Ying-yuan Li Wei-xuan Jiao School of Hydraulic Energy and Power EngineeringYangzhou UniversityYangzhou 225009China

Based on the computational fluid dynamics (CFD) and the experiment technology, this paper presents a new type of the twin-screw pump for the water-supply and studies its hydraulic performance with the hydraulic performance test. The internal flow characteristics and the hydraulic performance of the twin-screw pump are numerically simulated. The CFD results show that at different heads, the screw pressure gradually increases from the inlet end face along the axial direction of the screw to the outlet end face. The pressure distribution in the screw groove is relatively uniform, the screw clearance and the meshing area pressure are different from the screw groove pressure distribution. Under the same working condition of the head, the pressure distributions in the screw below and above the design speed are the same as the pressure distribution at the design speed, and with the range of the pressure value quite close. As the rotating speed increases furthermore, the flow rate and the volume efficiency of the pump both increase. At different rotating speeds, the velocity distributions along the axial direction of the screw are similar. A test rig is built, which consists of a closed-loop circuit, and the test results are found in good agreement with the CFD predictions. The experimental results show that the flow rate-head curves of the twin-screw pumps are similar at different rotating speeds. The research shows that the designed twin-screw pump enjoys a higher volumetric efficiency and a lower shaft power when the axial clearance is 0.08 mm-0.12 mm. When the clearance is 0.1 mm, the volumetric efficiency is the highest.

关键词： Twin-screw pump screw-rotor profile hydraulic characteristics screw clearances