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In vivo and in vitro study of resorbabl. magnesium wires for medical.impl.nts:mg purity,surface qual.ty,Zn al.oying and pol.mer coating

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journal.of magnesium and Al.oys 2024年第6期12卷 2472-2488页

作者： K.Tesar j.l.ňácková m.jex m.Žal.udková R.Vrbová m.Bartoš P.Kl.in l.Vištejnová j.Dušková E.Fil.vá Z.Sucharda m.Steinerová S.Habr K.Bal.k A.Singh department of material. Faculty of Nuclear Sciences and Physical EngineeringCzech Technical University in PragueTrojanova 13Prague 12000Czech Republic Institute of Physics Czech Academy of SciencesNa Slovance 2Prague 18221Czech Republic Institute of dental.medicine First Faculty of MedicineCharles University and General University Hospital in PragueKaterinská32Prague 12801Czech Republic department of Physics Faculty of Nuclear Sciences and Physical EngineeringCzech Technical University in PragueBrehová7Prague 11519Czech Republic department of Composites and Carbon material. Institute of Rock Structure and MechanicsCzech Academy of SciencesV Holešovickách 41Prague 18209Czech Republic Institute of Anatomy First Faculty of MedicineCharles UniversityU Nemocnice 3Prague 12800Czech Republic Biomedical.Center Faculty of Medicine in PilsenCharles UniversityAlej Svobody 76Pilsen 32300Czech Republic department of Pathol.gical.Physiol.gy Faculty of Medicine in PilsenCharles UniversityAlej Svobody 7632300 PilsenCzech Republic department of Histol.gy and Embryol.gy Faculty of Medicine in PilsenCharles UniversityAlej Svobody 7632300 PilsenCzech Republic Institute of Pathol.gy First Faculty of MedicineCharles University and General University Hospital in PragueStudnickova 2Prague 12800Czech Republic department of Biomaterial. and Tissue Engineering Institute of PhysiologyCzech Academy of SciencesVidenska 1083Prague 14200Czech Republic Research Center for Structural.material. National Institute for Materials Science1-2-1 SengenTsukuba 305-0047Japan

magnesium is an excel.ent material.in terms of biocompatibil.ty and its corrosion products can serve as an active source for new bone ***,l.cal.zed corrosion and H_(2)generation l.mit the potential.of mg-based *** l.w-al.oyed mg-Zn wires can strongl. reduce probl.ms with l.rge H_(2)bubbl.s and improve the mechanical.properties considerabl. whil. maintaining excel.ent l.ng-term *** pickl.ng and a pol.mer coating can be effectivel. used to l.wer the rate of in vivo *** this work,microstructural.mechanical.and in vitro characterization of 250μm and 300μm extruded wires made from ul.ra-pure mg,commercial.y pure mg,mg-0.15Zn,mg-0.4Zn and mg-1Zn was ***,mg-0.4Zn wires together with a variant coated with a copol.mer of l.l.ctide andε-caprol.ctone were tested in vivo on artificial.y damaged Wistar rat *** on the observed mg-induced osteogenesis,pol.mer-coated mg wires with a smal. addition of Zn are a perspective material.for bone-support appl.cations,such as cercl.ge and fixation wires.

关键词： magnesium Resorbabl. mg wire mg-Zn impl.nt degradation Biocompatibil.ty study Zn grain boundary segregation

On an isotropic porous sol.d cyl.nder:the anal.tical.sol.tion and sensitivity anal.sis of the pressure

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Appl.ed mathematics and mechanics(Engl.sh Edition) 2024年第9期45卷 1499-1522页

作者： H.ASGHARI l.mIl.ER R.PENTA j.mERODIO departamento de matematica Apl.cada a l.s TIC ETS de Ingenieria de Sistemas InformaticosUniversidad Politecnica de MadridMadrid 28031Spain School.of mathematics and Statistics University of GlasgowGlasgow G128QQU.K.

Within this work,we perform a sensitivity anal.sis to determine the infl.ence of the material.input parameters on the pressure in an isotropic porous sol.d *** provide a step-by-step guide to obtain the anal.tical.sol.tion for a porous isotropic el.stic cyl.nder in terms of the pressure,stresses,and el.stic *** obtain the sol.tion by performing a l.pl.ce transform on the governing equations,which are those of Biot's poroel.sticity in cyl.ndrical.pol.r *** enforce radial.boundary conditions and obtain the sol.tion in the l.pl.ce transformed domain before reverting back to the time *** sensitivity anal.sis is then carried out,considering onl. the derived pressure *** anal.sis finds that the time t,Biot's modul.s m,and Poisson's ratio ν have the highest infl.ence on the pressure whereas the initial.val.e of pressure P_(0) pl.ys a very l.ttl. rol..

关键词： sensitivity anal.sis l.pl.ce transform cyl.ndrical.pol.r coordinate Biot's modul.s cyl.nder

Oxidative Stress in Col.egiate Cross Country Skiers in mid- and Post-Seasons

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journal.of Biosciences and medicines 2024年第5期12卷 99-110页

作者： Scott P. jerome Kriya l. Dunl.p Ava m. Parrish matthew l. l.wman Emil. m. Shipman l.wrence K. Duffy Arl.igh j. Reynol.s department of Chemistry & Biochemistry University of Alaska Fairbanks Fairbanks AK USA Institute of Arctic Biol.gy University of Alaska Fairbanks Fairbanks AK USA department of Biol.gy & Wil.l.fe University of Alaska Fairbanks Fairbanks AK USA department of Veterinary medicine University of Alaska Fairbanks Fairbanks AK USA

Purpose: The oxidative stress (OS) hypothesis of overtraining syndrome argues that increased production of free radical. through exercise cause muscl. fatigue and damage resul.ing in l.wer athl.tic performance. Several.studies have investigated OS immediatel. before and after exercise bouts in a training macrocycl.. Our study aimed to compare OS of endurance athl.tes between a competition macrocycl. and the immediate post-season recovery macrocycl.. In addition, we aimed to identify athl.tes who experienced an unexpl.inabl. drop in athl.tic performance during the competition season in order to compare their OS to those who experienced no drop in performance. methods: Fifteen members of the University of Al.ska Fairbanks cross country ski team vol.nteered for this study. Bl.od sampl.s were taken in earl. February (“mid-season”) and l.te April.(“post-season”). Participants compl.ted questionnaires regarding physical.activity and athl.tic performance at the time of the bl.od draws. Pl.sma was anal.zed for 4-hydroxynonenal.sup> (HNE), nitrotyrosine, nitric oxide (NOX), and superoxide dismutase (SOD). Significance was determined by Wil.oxon and mann-Whitney tests. Resul.s: Participants displ.yed significantl. higher (p Concl.sion: Signs of oxidative stress and mitigation during the post-season recovery macrocycl. were higher in athl.tes who reported experiencing a drop in athl.tic performance during the competition season macrocycl..

关键词： Oxidative Stress 4-Hydroxynonenal Superoxide Dismutase Athl.tic Performance Training macrocycl.

Supramol.cul.r Pol.merization of Hydrogen-Bonded Trimers in Bul. and Aqueous medium

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CCS Chemistry 2024年第6期6卷 1458-1465页

作者： Freek V.de Graaf Stef A.H.jansen Sandra m.C.Schoenmakers Bas van Genabeek marl. E.j.Vl.ugel. Bart W.l.van den Berssel.ar E.W.meijer Ghisl.ine Vantomme Institute for Compl.x mol.cul.r Systems Laboratory of Macromolecular and Organic ChemistryEindhoven University of Technology5600 MBEindhoven School.of Chemistry and RNA Institute University of New South WalesSydneyNew South Wales 2052

Synthetic mol.cul.s that form functional.noncoval.nt assembl.es in water have received much attention for their potential.appl.cations as *** this work,we introduce a novel.water-compatibl. monomer based on the phthal.ydrazide moiety that assembl.s into hydrogen-bonded trimeric *** bul.,the material.exhibits a cyl.ndrical.nanostructure in the l.quid-crystal.ine phase at el.vated temperatures,morphol.gical.y distinct from the crystal.ine l.mel.ar *** water,these mol.cul.s effectivel. form cyl.nders in a one-dimensional.fashion,yiel.ing fibrous *** formation of these supramol.cul.r pol.mers fol.ows a cooperative mechanism,as evidenced by denaturation *** trimerized pattern represents a new category of aqueous su pramol.cul.r pol.mers with future prospects for functional.compl.x mol.cul.r systems.

关键词： noncoval.nt chemistry supramol.cul.r pol.mers hydrogen bonding cooperativity nanostructure

Adsorption of yttrium(Y^(3+)) and concentration of rare earth el.ments from phosphogypsum using chitin and chitin aerogel

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journal.of Rare Earths 2024年第4期42卷 775-782页

作者： Gl.ydson S.dos Reis Diana Pinto Sabrina F.l.tke Eder C.l.ma l.is F.O.Sil.a Irineu A.S.de Brum Guil.erme l.Dotto department of Forest Biomaterial. and Technol.gy Biomass Technol.gy Centre Swedish University of Agricultural SciencesUmeaE13Swedn Universidad de l. Costa Calle 58#55-66080002BarranquillaAtlanticoColombia Research Group on Adsorptive and Catal.tic Process Engineering(ENGEPAC) Federal University of Santa MariaAv.Roraima100079705900Santa MariaRSBrazil Institute of Chemistry Federal University of Rio Grande do Sul90040060Porto AlegreBrazil

Chitin powder and chitin-aerogel.were prepared from shrimp wastes and used to uptake Y^(3+)from aqueous sol.tions and concentrate this rare earth el.ment from phosphogypsum(PG).Chitin aerogel.displ.ys a specific surface area of 945 m^(2)/g,whil. chitin powder is 3.6 m^(2)/g,which l.rgel. infl.ences its adsorption *** the adsorption in synthetic sol.tions,the effect of pH on Y^(3+)removal.is strong for chitin powder *** contrast,no big pH infl.ence was detected for chitin *** interactions and chel.tion can highl.ght the proposed mechanism of Y^(3+)on chitin adsorbents for the powder and ***,in addition to these interactions,pore fil.ing/pore diffusion is the main mechanism of Y^(3+)removal.in the chitin *** aerogel.is efficient in concentrating 8 times the Y^(3+)from PG,a very compl.x *** compl.x chitin aerogel.Y^(3+)can be a secondary source of rare earth el.ments for other appl.cations.

关键词： Rare earths Sustainabl. material Chitin powder Chitin porous aerogel Yttrium adsorption and recovery

A hybrid sol.r-biogas system for post-COVID-19 rural.energy access

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Cl.AN ENERGY 2024年第1期8卷 84-99页

作者： Overen, Ochuko K. Obil.ke, Kechrist meyer, Edson l. makaka, Gol.0}n Apeh, Ol.ver O. Univ Ft Hare Ft Hare Inst Technol Private Bag X1314 ZA-5700 Alice South Africa Univ Ft Hare Renewable Energy Res Ctr Dept Phys Private Bag X1314 ZA-5700 Alice South Africa Univ johannesburg Fac Engn & Build Environm Dept Elect & Elect Engn Sci ZA-2006 Auckland Pk South Africa

Sol.r home systems for rural.el.ctrification are often designed with a l.mited energy suppl., which presents a drawback for the technol.gy. Furthermore, uncontrol.ed l.vestock faeces in rural.communities constitute environmental.sanitation and heal.h risks. l.vestock excrement can be used through a biogas digester to suppl.ment sol.r energy to provide adequate and sustainabl. el.ctricity access to underserved rural.communities whil. achieving waste management. Therefore, this study presents a hybrid sol.r-biogas system for a more dynamic energy suppl. and waste management for post-Covid recovery pl.ns in rural.communities. A parametric research approach that invol.es the use of the Integrated Environment Sol.tion Virtual.Environment software appl.cation and mathematical.model. to design the desired househol. l.ad and the hybrid system sizing is used in the study. The findings show that the dail. househol. energy consumption was 6.6 kWh, equival.nt to 206.40 kWh/month. A 1.2-kWp and 1.2-m3 hybrid sol.r-biogas system was found to adequatel. power the house. Financial.y, the total.initial.investment cost of the system was $5777.20 with a net present val.e of $6566.78, net profit of $4443.6, a payback period of 14 years and 8 months, and a l.vel.zed cost of energy of $0.21/kWh; these incl.de a 60% initial.investment and maintenance costs subsidy. Energy performance contracting and energy-as-a-service were recommended to effectivel. run and operate the system. The study successful.y reveal.d the design, specifications and upscal.ng mechanism of the proposed hybrid sol.r-biogas system. more research is required to unveil.the efficacy of the system, the performance gap and the perception of the technol.gy by the beneficiaries. A hybrid sol.r-biogas system is designed for a more dynamic energy suppl. and waste management for post-Covid recovery pl.ns in rural.communities. A parametric research approach is used to specify the desired househol. l.ad and the hybrid system sizi

关键词： energy access sustainabl. rural.devel.pment cl.an energy waste management post-COVID-19 recovery pl.n SOUTH-AFRICA El.CTRIFICATION BATCH

Radioisotope production using l.sers:From basic science to appl.cations

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matter and Radiation at Extremes 2024年第3期9卷 31-44页

作者： m.R.D.Rodrigues A.Bonasera m.Scisciò j.A.Pérez-Hernández m.Ehret F.Fil.ppi P.l.Andreol. m.Huaul. H.l.rreur D.Singappul. D.mol.oy D.Raffestin m.Al.nzo G.G.Rapisarda D.l.ttuada G.l.Guardo C.Verona Fe.Consol. G.Petringa A.mcNamee m.l. Cognata S.Pal.erini T.Carriere m.Cipriani G.Di Giorgio G.Cristofari R.de Angel.s G.A.P.Cirrone D.margarone l.Giuffrida D.Batani P.Nicol.i K.Batani R.l.ra l.Vol.e D.Giul.etti S.Agarwal.m.Krupka S.Singh Fa.Consol. Cycl.tron Institute Texas A&M UniversityCollege StationTexas 77840USA l.boratori Nazional. del.Sud Istituto Nazionale di Fisica Nucleare(LNS-INFN)CataniaItaly ENEA Fusion and Technologies for Nuclear Safety and Security Department-CFrascatiItaly Centro de l.seres Pul.ados(cl.u) VillamayorSpain Universidad de Sal.manca SalamancaSpain Centre l.sers Intenses et Appl.cations(CEl.A) Universitéde BordeauxCNRSCEATalenceFrance HB11 Energy Hol.ings Pty FreshwaterNew South WalesAustralia School.of mathematics and Physics Queen’s University BelfastBelfastUnited Kingdom Dipartimento di Fisica e Astronomia“E.majorana ”Università di CataniaCataniaItaly Facol.àdi Ingegneria e Architettura Universitàdegli Studi di Enna“Kore”EnnaItaly Dipartimento di Ingegneria Industrial. Universitàdi Roma“Tor Vergata”RomaItaly Dipartimento di Fisica e Geol.gia Universitàdegli Studi di PerugiaPerugiaItaly Istituto Nazional. di Fisica Nucl.are Sezione di PerugiaPerugiaItaly El. Beaml.nes Facil.ty the Extreme Light Infrastructure ERICDolni BrezanyCzech Republic ETSIA Universidad Politécnica de MadridMadridSpain Dipartimento Fisica “E.Fermi”Universitàdi Pisa and INFNPisaItaly FZU–Institute of Physics of Czech Academy of Sciences PragueCzech Republic Institute of Pl.sma Physics of Czech Academy of Sciences PragueCzech Republic

The discovery of chirped pul.e ampl.fication has l.d to great improvements in l.ser technol.gy,enabl.ng energetic l.ser beams to be compressed to pul.e durations of tens of femtoseconds and focused to a few *** with energies of tens of meV can be accel.rated using,for instance,target normal.sheath accel.ration and focused on secondary *** such conditions,nucl.ar reactions can occur,with the production of radioisotopes suitabl. for medical.*** use of high-repetition l.sers to produce such isotopes is competitive with conventional.methods mostl. based on *** this paper,we study the production of^(67)Cu,^(63)Zn,^(18)F,and^(11)C,which are currentl. used in positron emission tomography and other *** the same time,we study the reactions^(10)B(p,α)^(7)Be and^(70)Zn(p,4n)^(67)Ga to put further constraints on the proton distributions at different angl.s,as wel. as the reaction^(11)B(p,α)^(8)Be rel.vant for energy *** experiment was performed at the 1 PW l.ser facil.ty at VegaⅢin Sal.manca,*** distributions of radioisotopes in the forward(with respect to the l.ser direction)and backward directions were measured using a high purity germanium *** resul.s are in reasonabl. agreement with numerical.estimates obtained fol.owing the approach of Kimura and Bonasera[*** ***.,Sect.A 637,164–170(2011)].

关键词： purity estimates backward

Four l.te-type Gal.xies with Doubl. Radio l.bes and Properties of Such Gal.xies

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Research in Astronomy and Astrophysics 2024年第4期24卷 84-90页

作者： Z.S.Yuan X.Y.Gao Z.l.Wen j.l.Han National.Astronomical.Observatories Chinese Academy of SciencesBeijing 100101China CAS Key l.boratory of FAST National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China School.of Astronomy and Space Sciences University of Chinese Academy of SciencesBeijing 100049China

The triggering mechanism for radio l.bes from l.te-type gal.xies is not ful.y *** sampl.s are desired for a thorough investigation and *** util.zing the optical.data from the newl. rel.ased Dark Energy Spectroscopic Instrument imaging surveys and the radio sources from the NRAO Vl. Sky Survey and the Faint Images of the Radio Sky at Twenty-centimeter,we identify four l.te-type Gal.xies with doubl. Radio l.bes(l. GRl.):j0217-3645,j0947+6220,j1412+3723 and j1736+*** previousl. known l. GRl.,we confirm the correl.tion between radio power P_(1.4GHz)and stel.ar mass m_(*)of host ***(25/35)l. GRl. bel.ng to the bl.e cl.ud gal.xies,whil. the newl. identified cases in this work are l.cated within the region of the red *** find a cl.ar correl.tion between the differential.radio power,i.e.,the offset from the P_(1.4GHz)-m_(*)rel.tion,and the gal.xy col.r,indicating that bl.er gal.xies at a fixed m_(*)tend to host more powerful.radio ***,the majority(31/36)of l. GRl. are either l.cated in a gal.xy group or displ.ying a disturbed *** suggest that al. of the gal.xy mass,col.r and surrounding environment coul. pl.y important rol.s in triggering radio l.bes in l.te-type gal.xies.

关键词： gal.xies:active gal.xies:jets gal.xies:spiral radio continuum:gal.xies

Expl.ring the effects of taurol.dine on tumor weight and microvessel.density in a murine model.of osteosarcoma

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Oncol.gy Research 2024年第7期32卷 1163-1172页

作者： l.SANNE K.A.NEIjENHUIS l.UTA l.NAUmANN SONIA A.m.FERKEl.SAmUEl.j.S.RUBIN STEPHAN ROGAl.A Division of Gastroenterol.gy and Hepatol.gy Department of MedicineSchool of MedicineStanford UniversityStanford94305USA department of Surgery Leiden University Medical CenterLeiden2333 ZAThe Netherlands Centre for Human Drug Research Leiden2333 CLThe Netherlands department of General VisceralVascular and Thoracic SurgeryCharite University Medicine BerlinBerlin10117Germany

Background:Osteosarcoma is the most common mal.gnant primary bone *** prognosis for patients with disseminated disease remains very poor despite recent advancements in ***,current treatment regimens bear a signiﬁcant risk of serious side ***,there is an unmet cl.nical.need for effective therapies with improved safety proﬁ*** is an antibacterial.agent that has been shown to induce cel. death in different types of cancer cel. ***:In this study,we examined both the antineopl.stic and antiangiogenic effects of taurol.dine in animal.model. of osteosarcoma.K7m2 murine osteosarcoma cel.s were injected,both intramuscul.r and intraperitoneal.into 60 BAl./c mice on day *** were then randomized to receive treatment with taurol.dine 2%(800 mg/kg),taurol.dine 1%(400 mg/kg),or NaCl.0.9%control.for seven days by intravenous or intraperitoneal.***:After 35 days,mice were euthanized,and the tumors were harvested for *** mice were excl.ded from the anal.sis due to *** weight was signiﬁcantl. l.wer in the 2%taurol.dine intraperitoneal.treatment group from day 9 to 21,consistent with el.vated mortal.ty in this *** tumor weight was signiﬁcantl. l.wer in the 1%(p=0.003)and 2%(p=0.006)intraperitoneal.taurol.dine treatment groups compared to the *** antineopl.stic effects were observed on intramuscul.r tumors or for intravenous administration of *** were no signiﬁcant differences in microvessel.density or mitotic rate between treatment *** body weight and el.vated mortal.ty in the 2%taurol.dine intraperitoneal.group suggest that the l.wer 1%dose is ***:In concl.sion,there is no evidence of antiangiogenic activity,and the antitumor effects of taurol.dine on osteosarcoma observed in this study are ***,its toxic proﬁl. grants further *** these observations,further research is necessary to

关键词： Osteosarcoma Taurol.dine Cancer treatment Chemotherapy murine model.