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Factors associated with time to laparoscopic cholecystectomy for acute cholecystitis

World Journal of Gastroenterology 2008年第7期14卷 1084-1090页

作者： Chris n Daniak david Peretz Jonathan M Fine Yun Wang Alan K Meinke William B Hale Section of Gastroenterology Norwalk Hospital Norwalk CT United States Department of Internal Medicine Norwalk Hospital Norwalk CT United States Center for Outcomes Research and Evaluation Yale University/Yale New Haven Health System New Haven CT United States Department of Surgery Norwalk Hospital Norwalk CT United States

AIM: To determine patient and process of care factors associated with performance of timely laparoscopic cholecystectomy for acute cholecystitis. METHODS: A retrospective medical record review of 88 consecutive patients with acute cholecystitis was conducted. Data collected included demographic data, co-morbidities, symptoms and physical findings at presentation, laboratory and radiological investigations, length of stay, complications, and admission service (medical or surgical). Patients not undergoing cholecystectomy during this hospitalization were excluded from analysis. Hierarchical generalized linear models were constructed to assess the association of pre-operative diagnostic procedures, presenting signs, and admitting service with time to ***: Seventy cases met inclusion and exclusion criteria, among which 12 were admitted to the medical service and 58 to the surgical service. Mean ± SD time to surgery was 39.3 ± 43 h, with 87% of operations performed within 72 h of hospital arrival. In the adjusted models, longer time to surgery was associated with number of diagnostic studies and endoscopic retrograde cholangio-pancreatography (ERCP, P = 0.01) as well with admission to medical service without adjustment for ERCP (P nts undergoing both magnetic resonance cholangiopancreatography (MRCP) and computed tomography (CT) scans experienced the longest waits for surgery. Patients admitted to the surgical versus medical service underwent surgery earlier (30.4 ± 34.9 vs 82.7 ± 55.1 h, P ns (12% vs 58%, P nd shorter length of stay (4.3 ± 3.4 vs 8.1 ± 5.2 d, P nCLUSIOn: Admission to the medical service and performance of numerous diagnostic procedures, ERCP, or MRCP combined with CT scan were associated with longer time to surgery. Expeditious performance of ERCP and MRCP and admission of medically stable patients with suspected cholecystitis to the surgical service to speed up ti

关键词： Acute cholecystitis Laparoscopic cholecystectomy Endoscopic retrograde cholangiopancreatography Post-operative complications

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Influence of Livestock Soil Eutrophication on Floral Composition in the Pyrenees Mountains

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Journal of Mountain Science 2008年第1期5卷 63-72页

作者： BADíA david MARTí Clara SánCHEZ José Ramón FILLAT Federico AGUIRRE Javier GóMEZ Daniel High School of Agricultural Engineering E-22071 HuescaSpain Pyreneean Institut of Ecology CSICE-22700 JacaSpain

Livestock behaviour in the Pyrenees includes free grazing and a long resting period that provokes the accumulation of dung and urine in some places,so-called camping areas. The aims of this study were (i) to analyze any change in floral composition,and in nutritional and chemical contents of plants in a livestock camping area; and (ii) to relate the floral composition with soil chemical properties. In a linear transect,five sampling zones were established,from the centre of the camping area to the surrounding nardus stricta-dominant pasture. The above ground plant biomass and the topsoil were sampled in each zone with 6 replicates per zone. Plant species were classified and weighed to calculate above ground biomass,nutritional and chemical contents,and Shannon diversity and evenness indices. Additionally,soils were sampled in two periods,at the beginning and at the end of grazing period. Soil available nutrients (nitrate,ammonium,phosphorus,potassium,calcium and magnesium),total nitrogen,organic carbon and pH were measured. Plant chemical contents (protein,lignin and others) were significantly related to the proportions of grasses,legumes and other plants; so,the protein content is positively correlated with legumes plant biomass while lignin content is negatively correlated with grasses. Both plant and soil nutrients increased linearly towards the centre of the camping area. However,the relationship among plant species richness,diversity and evenness relative to its position along the studied transect was bell-shaped. From the outskirts to the centre of the camping area,plants with low nutrient demand were progressively replaced by those with medium and high nutrients demand and by pioneers. nardus stricta-dominant pasture has low plant diversity and plant nutrient content as well as a poor soil nutrient availability. The presence of the camping area introduced patches with more soil nutrients and new species in the large spatial scale. However at a small spatial s

关键词： Plant diversity species richness soil chemistry European mountains Pyrenees

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Templated Colloidal Self-Assembly for Lattice Plasmon Engineering

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Accounts of Materials Research 2021年第9期2卷 816-827页

作者： Leonardo Scarabelli david Vila-Liarte Agustín Mihi Luis M.Liz-Marzán Institute of Materials Science of Barcelona ICMAB-CSIC08193 BellaterraSpain CIC biomaGUnE Basque Research and Technology Alliance(BRTA)20014 Donostia-San SebastiánSpain Centro de Investigación Biomédica en Red BioingenieríaBiomateriales y Nanomedicina(CIBER-BBN)20014 Donostia-San SebastiánSpain Ikerbasque Basque Foundation for Science48013 BilbaoSpain

COnSPECTUS:Over the past 30 years,the engineering of plasmonic resonances at the nanoscale has progressed dramatically,with important contributions in a variety of different fields,including chemistry,physics,biology,engineering,and ***,heavy optical losses related to the use of noble metals for the fabrication of plasmonic structures hindered their application in various ***,an answer to these long-lasting issues emerged in the use of lattice plasmon resonances(LPRs,also called surface lattice resonances),bringing new excitement in the field of ***,the organization of plasmonic nanoparticles into ordered arrays enables far-field coupling of the scattered light exploiting the diffraction modes of the array,generating plasmonic resonances with bandwidths as narrow as a few nanometers,corresponding to an increase of over 10-fold in the quality factors compared to localized plasmon *** such,LPRs offer new opportunities to harness light−matter interactions at the nanoscale,while generating renewed interest in the self-assembly of colloidal metal nanoparticles,as a scalable approach to the preparation of such plasmonic *** self-assembly emerged as one of the most versatile approaches,being compatible with soft-lithographic techniques such as nanoimprint lithography and amenable to a variety of materials,colloids,and *** self-assembly additionally allows the preparation of arrays where the repeating units are composed of multiple self-assembled nanoparticles(i.e.,plasmonic clusters).In this system,near-field coupling can be finely tuned,thereby showing promising results in biosensing,catalysis,or plasmonic *** this Account,we review the preparation of ordered arrays of clusters of plasmonic *** present various aspects involved in the templated self-assembly of colloidal nanoparticles,with the aim of achieving at the same time close-packed structures within each cavity

关键词： coupling enable versatile

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Water balloon-induced orbital fracture in an aviator

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Military Medical Research 2020年第2期7卷 245-248页

作者： Timothy E.Holland david M.Smith Guy n.Gibson Jared G.Brinkerhoff Flight and Operational Medical Clinic 78th Medical Group655 Seventh StreetRobins Air Force BaseRobinsGA 31098USA Department of Radiology Ehrling Bergquist Clinic2501 Capehart RdOffutt AFBNEOffutt 68113-2160USA Flight and Operational Medical Clinic 5th Medical Group194 Missilie AveMinot AFBNDMinot 58705USA

Background:Orbital fractures are common injuries found in facial *** etiologies of orbital fractures include motor vehicle collisions and *** report the case of a 32-year-old male who suffered an orbital fracture from a water ***,we describe the aeromedical complications that may result from this ***,we attempt to answer the question of when a patient may return to flying after sustaining such an injury through review of the *** presentation:A 32-year-old male pilot with the United States Air Force was at an outdoor event with his unit when he was struck with a water balloon launched from a sling shot into his left *** afterwards,he had an onset of subcutaneous emphysema and was escorted to a nearby Emergency *** tomography identified an orbital fracture with associated orbital and subcutaneous *** patient was evaluated by a plastic surgeon and was determined not to be a surgical *** weeks later,he returned to flying ***:Water balloons are thought to be safe and harmless ***,when coupled with sling shots,water balloons can become formidable projectiles capable of significant orbital injury including orbital *** injuries are concerning to aviators,as the most common sites for fractures of the orbit are the thin ethmoid and maxillary bones adjacent to the *** altitude,gases in the sinuses may expand and enter the orbit through these fractures,which may suddenly incapacitate the *** is important for flight surgeons to identify and assess these individuals to determine suitability for flying.

关键词： Boyle’s law Orbital emphysema Facial fracture

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Evidence for Mesoproterozoic collision,deep burial and rapid exhumation of garbenschiefer in the namaqua Front,South Africa

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Geoscience Frontiers 2020年第2期11卷 511-531页

作者： Valby Van Schijndel david HCornell Robert Anczkiewicz Anders Schersten Department of Earth Sciences University of GothenburgSE-40530Sweden Department of Earth Sciences University of StellenboschPrivate Bag X1Matieland7602South Africa Institute of Geological Sciences Polish Academy of SciencesKrakow Research CentreUl.Senacka 131-002KrakowPoland Lund University Department of GeologyS€olvegatan 12SE-22362LundSweden University of Potsdam Institute of Earth and Environmental Sciences14476PotsdamGermany

Metamorphic provinces such as the^1 Ga Grenvillian,~400 Ma Caledonide and Triassic Qinling Provinces often contain rocks with high-pressure assemblages such as eclogites,which formed at mantle depths in subduction *** are evidence of the accretion of terranes by subduction of oceans and collision to form large tectonostratigraphic *** Mesoproterozoic namaqua-natal Province comprises a number of terranes thought to have been assembled by plate-tectonic processes,but they have generally yielded metamorphic pressures below 5 kbar,corresponding tong evidence for subduction *** Kaaien Terrane in the namaqua Front contains two large garbenschiefer units with the unusual paragenesis garnet-hornblende-epidote-white *** protoliths are graywackes influenced by andesitic volcanism during their deposition at^1870 Ma,in a passive margin of the Rehoboth Province or Kaapvaal *** garnet growth dated at 11655 Ma culminated in peak metamorphic conditions of 64530C and 10.40.7 kbar,corresponding to 40 km *** is attributed to subduction of these rocks before collision between the overriding arc-related Areachap Terrane,the Kaaien Terrane and the Kaapvaal-Rehoboth cratonic block during the namaqua *** of the garbenschiefer slabs was followed by rapid cooling,as the 11435 Ma argon dates of hornblende and white mica,with closure temperatures^540C and^440C respectively,are the same within *** was probably due to tectonic juxtaposition of the garbenschiefer slab with much cooler rock *** exhumation was accommodated along the Trooilapspan-Brakbosch Shear Zone due to ongoing *** components of the namaqua Front have distinctly different P-T-t paths,exemplified by greenschist metamorphism in the 1300 Ma Wilgenhoutsdrift Group,and medium-pressure metamorphism in the Areachap *** were juxtaposed by late-tectonic uplift and transpr

关键词： Collision orogeny P-T-t path Garbenschiefer Lu–Hf garnet U–Pb zircon 40Ar/39Ar dating

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有FACTS装置的电力系统在市场环境下的最优调度

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电力系统自动化 2001年第4期25卷 20-24,44页

作者： S.n.Singh A.K.david 香港理工大学电机工程系中国香港

随着电力工业重构的不断深入 ,转运业务需求的增加要求系统提供更高的输送能力。FACTS技术的应用能够提高系统的输电能力、降低网损、改善系统的稳定性、降低电能成本 ,促使电能交易顺利完成。依据有功性能指标 ,文中提出了 FACTS装置... 详细信息

随着电力工业重构的不断深入 ,转运业务需求的增加要求系统提供更高的输送能力。FACTS技术的应用能够提高系统的输电能力、降低网损、改善系统的稳定性、降低电能成本 ,促使电能交易顺利完成。依据有功性能指标 ,文中提出了 FACTS装置的优化配置方法 ,并通过解最优潮流问题得到 FACTS装置的可控参数值 ,同时讨论了 FACTS装置对系统实时电价的影响。用IEEE— 1 4节点算例验证了所提算法的有效性。

关键词：电力系统最优调度 FACTS装置市场环境

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Constructing the toolbox:Patient-specific genetic factors of altered fracture healing

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Genes & Diseases 2014年第2期1卷 140-148页

作者： Hicham Drissi david n.Paglia Farhang Alaee Ryu Yoshida new England Musculoskeletal Institute and Department of Orthopaedic Surgery United States

The multifaceted sequence of events that follow fracture repair can be further complicated when considering risk factors for impaired union,present in a large and growing percentage of the *** factors such as diabetes,substance abuse,and poor nutrition affect both the young and old,and have been shown to dramatically impair the body’s natural healing *** this end,biotherapeutic interventions such as ultrasound,electrical simulation,growth factor treatment(BMP-2,BMP-7,PDGF-BB,FGF-2)have been evaluated in preclinical models and in some cases are used widely for patients with established non-union or risk/indication or impaired healing(***,BMP-2,etc.).Despite the promise of these interventions,they have been shown to be reliant on patient compliance and can produce adverse side effects such as heterotopic *** and cell therapy approaches have attempted to apply controlled regimens of these factors and have produced promising ***,there are safety and efficacy concerns that may limit the translation of these *** addition,none of the above mentioned approaches consider genetic variation between individual *** clinical and preclinical studies have demonstrated a genetic component to fracture repair and that SnPs and genetic background variation play major roles in the determination of healing *** this,there is a need for preclinical data to dissect the mechanism underlying the influence of specific gene loci on the processes of fracture healing,which will be paramount in the future of patient-centered interventions for fracture repair.

关键词： Bone repair Fracture healing Genetics Orthobiologics Patient factors

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Science Letters:Visual odometry for road vehicles—feasibility analysis

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第12期8卷 2017-2020页

作者： SOTELO Miguel-angel GARCíA Roberto PARRA Ignacio FERnnDEZ david GAVILn Miguel LVAREZ Sergio nARAnJO José-eugenio Department of Electronics University of Alcalá Alcalá de Henares 28871 Spain Department of Informatics Industrial Automation Institute CSIC Madrid Spain

Estimating the global position of a road vehicle without using GPS is a challenge that many scientists look forward to solving in the near future. normally, inertial and odometry sensors are used to complement GPS measures in an attempt to provide a means for maintaining vehicle odometry during GPS outage. nonetheless, recent experiments have demonstrated that computer vision can also be used as a valuable source to provide what can be denoted as visual odometry. For this purpose, vehicle motion can be estimated using a non-linear, photogrametric approach based on RAndom SAmple Consensus (RAnSAC). The results prove that the detection and selection of relevant feature points is a crucial factor in the global performance of the visual odometry algorithm. The key issues for further improvement are discussed in this letter.

关键词： 3D visual odometry Ego-motion estimation RAndom SAmple Consensus (RAnSAC) Photogrametric approach

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Dual role of FGF in proliferation and endoreplication of Drosophila tracheal adult progenitor cells

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Journal of Molecular Cell Biology 2020年第1期12卷 32-41页

作者： Cristina de Miguel Josefa Cruz david Martin Xavier Franch-Marro Institute of Evolutionary Biology(Consejo Superior de Investigaciones Cientificas-Universitat Pompeu Fabra) Passeig Maritim de la Barceloneta 3708003 BarcelonaSpain

Adult progenitor cells activation is a key event in the formation of adult *** Drosophilat formation of abdominal adult trachea depends on the specific activation of tracheal adult progenitors(tracheoblasts)at the Tr4 and Tr5 spiracular *** of these tracheoblasts generates a pool of tracheal cells that migrate toward the posterior part of the trachea by the activation of the branchless/fibroblast growth factor(Bnl/FGF)signaling to form the abdominal adult ***,we show that,in addition to migration,Bnl/FGF signaling,mediated by the transcription factor Pointed,is also required for tracheoblast *** tracheoblast activation relies on the expression of the FGF ligand bnl in their nearby ***,we show that,in the absence of the transcription factor Cut(Ct),Bnl/FGF signaling induces endoreplication of tracheoblasts partially by promoting fizzy-related ***,our results suggest a dual role of Bnl/FGF signaling in tracheoblasts,inducing both proliferation and endoreplication,depending on the presence or absence of the transcription factor Ct,respectively.

关键词： FGF trachea adult progenitors cut proliferation endoreplication Pnt Fzr

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Mycorrhizal Symbioses of Cotton Grown on Sodic Soils:A Review from an Australian Perspective

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Pedosphere 2017年第6期27卷 1015-1026页

作者： Samieh ESKAnDARI Christopher n.GUPPY Oliver G.G.KnOX david BACKHOUSE Rebecca E.HALInG School of Environmental and Rural Science University of New EnglandArmidale NSW 2351(Australia) CSIRO Agriculture Canberra ACT 2601(Australia)

The majority of terrestrial plants form some type of mycorrhizal *** established symbiosis therefore exists in most commercially important crops, which includes *** mycorrhizal fungus(AMF) can colonise 50%–90% of cotton root length under field and controlled *** improves growth and nutrient uptake(especially phosphorus) of cotton,particularly at the early growth *** symbioses help plants to counter the stresses imposed by physical and chemical soil constraints; however, adverse environmental conditions may restrict the mycorrhizal associations and consequently may reduce nutrient uptake and impair plant *** Australia, cotton is mainly grown on sodic soils that contain more than 6% of the total cations as exchangeable *** levels of sodium in the soil create adverse physical and chemical soil conditions that may negatively affect mycorrhizal symbioses of *** review discusses the cotton mycorrhizal colonisation, plant growth, and disease protection effects, potential negative effects of physical and chemical properties of sodic soils, and influences of some agronomic management *** addition, the research gaps were identified and some practical applications of the research outcomes were suggested.

关键词： agronomic management axbuscular mycorrhizal fungus (AMF) disease protection exchangeable sodium pathogen,plant growth soil property

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