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Identification of phytochemical compounds in Calophyllum inophyllum leaves

Asian Pacific Journal of Tropical Biomedicine 2017年第9期7卷 773-781页

作者： david Febrilliant susanto Hakun Wirawasista Aparamarta Arief Widjaja Setiyo Gunawan Department of Chemical Engineering Institut Teknologi Sepuluh NopemberSurabaya 60111Indonesia

Objectives: To investigate the proximate composition, mineral content, and phytochemical compounds in Calophyllum inophyllum(C. inophyllum) leaves. Moreover,isolation and identification of pyrene were also ***: C. inophyllum leaves were extracted with methanol by percolation *** proximate composition of C. inophyllum leaves was analyzed by standard *** contents in this plant were analyzed by using atomic absorption spectrophotometer. Phytochemical screening and analysis of this plant were performed by spectrophotometric method. Washing method with carbon disulfide was used for isolating dihydropyrene compound from C. inophyllum leaves ***: The result revealed that C. inophyllum leaves contained 11.24% moisture,4.75% ash, 6.43% crude protein, 23.96% crude fiber, 9.91% carbohydrate, and energy(79.17 kcal/100 g). The leaves also contained 0.007% iron, 1.240% calcium, 0.075%sodium, 0.195% magnesium, 0.100% ppm potassium, and 0.040% phosphorus. Moreover, 11.51% alkaloid, 2.48% triterpenoid, 2.37% flavonoid, 7.68% tannin, 2.16%saponin, 2.53% polyphenol, were identified in the methanolic crude extracts of C. inophyllum leaves. It was found that trans-2-[2-(trifluoromethyl)phenyl]-10 b,10 c-dimethyl-10 b,10 c-dihydropyrene was obtained at purity of 79.18%(22.17% yield)from C. inophyllum ***: C. inophyllum leaves may be used as a good source of fiber. It was found that C. inophyllum leaves have the potential as herbal drugs due to their phytochemical content. The separation, isolation, and purification of bioactive compounds from this methanolic crude extract and their biological activity are under further investigation.

关键词： Calophyllum inophyllum leaves Crude extracts Proximate composition Mineral composition Phytochemical

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Effectiveness of non-pyrimethamine-based regimens for toxoplasma encephalitis:A systematic and meta-synthesis study

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Asian Pacific Journal of Tropical Medicine 2022年第3期15卷 106-113页

作者： david susanto Arthur H.P.Mawuntu Finny Warouw Windy M.V.Wariki Neurology Department Faculty of MedicineSam Ratulangi University/R.D.Kandou HospitalManadoIndonesia Department of Community Medicine Faculty of MedicineSam Ratulangi UniversityManadoIndonesia

Objective:To examine the differences in effectiveness and side effects between pyrimethamine-based and non-pyrimethamine-based regimens for toxoplasma encephalitis since the availability of pyrimethamine in Indonesia is currently limited due to its withdrawal from the ***:A systematic review and meta-synthesis study that was carried out by following a protocol guided by the Preffered Reporting Items for Systematic Review and Meta-analysis(PRISMA).Effectiveness measures included clinical improvement,mortality,and radiological *** evaluated selected articles narratively because of the limitations of *** risk of bias in RCTs was assessed using the Cochrane Risk of Bias tool for RCT(ROB 2.0)and cohort studies were assessed using the Risk of Bias In Non-Randomized Studies of Interventions(ROBINS-1)*** quality was assessed using the GradePro ***:We included two retrospective cohort studies and one *** outcome assessment in these three studies did not show significant difference in effectiveness between pyrimethamine-based and non-pyrimethamine-based regimens for toxoplasma encephalitis ***,drug side effects were consistently higher in the pyrimethamine-based ***:This study has a high risk of *** quality of the research also has a low recommendation ***,the results may be considered for application if a standard regimen is not available.

关键词： Toxoplasma encephalitis Alternative treatment Without pyrimethamine Systematic review Meta-synthesis

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Making bridges between preclinical and clinical insights into age-related cognitive decline

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Neural Regeneration Research 2025年第8期20卷 2321-2322页

作者： david VC Brito Clévio Nóbrega Algarve Biomedical Center-Research Institute(ABC-RI) Campus GambelasFaroPortugal Algarve Biomedical Center-(ABC) Campus GambelasFaroPortugal Faculty of Medicine and Biomedical Sciences(FMCB) University of AlgarveGambelas CampusFaroPortugal

With people living longer,the societal impact of age-related cognitive decline is becoming more pronounced(Crimmins,2015).Thus,it is increasingly important to comprehend the cognitive shifts linked to aging-whether th... 详细信息

关键词： bridges becoming insight

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Women in visual neural regeneration research

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Neural Regeneration Research 2025年第2期20卷 489-490页

作者： Tonia S.Rex david J.Calkins Vanderbilt Eye Institute Vanderbilt University Medical CenterNashvilleTNUSA

The year 2024 marks the 60^(th)anniversary of Title IX and 25 years since the New York Times revealed bias against female faculty members at the Massachusetts Institute of *** take an opportunity here to examine the state of gender bias in a relatively new yet already prominent field,neural regeneration in the visual system,for which there is a well-defined context useful for this *** National Eye Institute(NEI)provided the first round of research funding for its Audacious Goals Initiative(AGI)on visual neural regeneration in 2013 and the last round in ***,we focus on this *** sources included PubMed,the National Science Foundation(NSF),the NEI,the Blue Ridge Institute for Medical Research and data from the major professional organization for eye and vision research,the Association for Research in Vision and Ophthalmology(ARVO).

关键词： neural visual Times

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Traffic Flow Prediction with Heterogeneous Spatiotemporal Data Based on a Hybrid Deep Learning Model Using Attention-Mechanism

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Computer Modeling in Engineering & Sciences 2024年第8期140卷 1711-1728页

作者： Jing-Doo Wang Chayadi Oktomy Noto susanto Departement of Computer Science and Information Engineering Asia UniversityTaichungTaiwanChina Departement of Information Technology Universitas Muhammadiyah YogyakartaYogyakartaIndonesia

A significant obstacle in intelligent transportation systems(ITS)is the capacity to predict traffic *** advancements in deep neural networks have enabled the development of models to represent traffic flow ***,accurately predicting traffic flow at the individual road level is extremely difficult due to the complex interplay of spatial and temporal *** paper proposes a technique for predicting short-term traffic flow data using an architecture that utilizes convolutional bidirectional long short-term memory(Conv-BiLSTM)with attention *** studies neglected to include data pertaining to factors such as holidays,weather conditions,and vehicle types,which are interconnected and significantly impact the accuracy of forecast *** addition,this research incorporates recurring monthly periodic pattern data that significantly enhances the accuracy of forecast *** experimental findings demonstrate a performance improvement of 21.68%when incorporating the vehicle type feature.

关键词： Traffic flow prediction sptiotemporal data heterogeneous data Conv-BiLSTM data-centric intra-data

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Traffic Flow Prediction with Heterogenous Data Using a Hybrid CNN-LSTM Model

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Computers, Materials & Continua 2023年第9期76卷 3097-3112页

作者： Jing-Doo Wang Chayadi Oktomy Noto susanto Departement of Computer Science and Information Engineering Asia UniversityTaichungTaiwan Departement of Information Technology Universitas Muhammadiyah YogyakartaYogyakartaIndonesia

Predicting traffic flow is a crucial component of an intelligent transportation *** monitoring and predicting traffic flow remains a challenging ***,existingmethods for predicting traffic flow do not incorporate various external factors or consider the spatiotemporal correlation between spatially adjacent nodes,resulting in the loss of essential information and lower forecast *** the other hand,the availability of spatiotemporal data is *** research offers alternative spatiotemporal data with three specific features as input,vehicle type(5 types),holidays(3 types),and weather(10 conditions).In this study,the proposed model combines the advantages of the capability of convolutional(CNN)layers to extract valuable information and learn the internal representation of time-series data that can be interpreted as an image,as well as the efficiency of long short-term memory(LSTM)layers for identifying short-term and long-term *** approach may utilize the heterogeneous spatiotemporal correlation features of the traffic flowdataset to deliver better performance traffic flow prediction than existing deep learning *** research findings show that adding spatiotemporal feature data increases the forecast’s performance;weather by 25.85%,vehicle type by 23.70%,and holiday by 14.02%.

关键词： Heterogeneous data traffic flow prediction deep learning CNN LSTM

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Pilot scale autothermal gasification of coconut shell with CO2-O2 mixture

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Frontiers in Energy 2015年第3期9卷 362-370页

作者： Bayu PRABOWO Herri susanto Kentaro UMEKI Mi YAN Kunio YOSHIKAWA Department of Environmental Science and Technology Tokyo Institute of Technology Yokohama 226-8503 Japan Institute of Energy and Power Engineering Zhejiang University of Technology Hangzhou 310014 China Department of Chemical Engineering Institut Teknologi Bandung Bandung 40132 Indonesia Division of Energy Science Lulea University of Technology Lulea 971 87 Sweden Institute of Energy and Power Engineering Zhejiang University of Technology Hangzhou 310014 China Department of Environmental Science and Technology Tokyo Institute of Technology Yokohama 226-8503 Japan

This paper explored the feasibility and benefit of CO2 utilization as gasifying agent in the autothermal gasification process. The effects of CO2 injection on reaction temperature and producer gas composition were examined in a pilot scale downdraft gasifier by varying the CO2/C ratio from 0.6 to 1.6. O2 was injected at an equivalence ratio of approximately 0.33-0.38 for supply- ing heat through partial combustion. The results were also compared with those of air gasification. In general, the increase in CO2 injection resulted in the shift of combustion zone to the downstream of the gasifier. However, compared with that of air gasification, the long and distributed high temperature zones were obtained in CO2-O2 gasification with a CO2/C ratio of 0.6-1.2. The progress of the expected CO2 to CO conversion can be implied from the relatively insignificant decrease in CO fraction as the CO2/C ratio increased. The producer gas heating value of CO2-O2 gasification was consistently higher than that of air gasification. These results show the potential of CO2-O2 gasification for producing high qualityproducer gas in an efficient manner, and the necessity for more work to deeply imply the observation.

关键词： Keywords biomass gasification CO2 downdrafl gasifier,autothermal

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Paper wasps larval formations from the perspective of physics

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Insect Science 2023年第6期30卷 1827-1830页

作者： Aan Priyanto Dian Ahmad Hapidin William Xaveriano Waresindo susanto susanto Mahardika Prasetya Aji Khairurrijal Khairurrijal Doctoral Program of Physics Faculty of Mathematics and Natural SciencesInstitut Teknologi BandungBandungJawa BaratIndonesia Department of Physics Institut Teknologi BandungBandungJawa BaratIndonesia Physics Division Cahaya Rancamaya Islamic Boarding SchoolBogorJawa BaratIndonesia Department of Physics Universitas Negeri SemarangSemarangJawa TengahIndonesia Faculty of Science Department of PhysicsInstitut Teknologi SumateraJalan Terusan RyacuduLampung SelatanIndonesia

Dear Editor,Paper wasps have been the subject of numerous studies across various disciplines,including biology(Grinsted&Field,2017),ecology(Sheehan et al.,2015),chemistry(Cini et al.,2011),and physics(Chawla et al.,2020).Previous research has primarily focused on their behavior from biological and ecological ***,recent investigations from a physics standpoint have also explored their nesting behavior,including the use of defensive structures.

关键词： al. formations primarily

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Peer educator training program for enhancing knowledge on issues in the growth and development of adolescents and risk behavior problems in Indonesian context

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Frontiers of Nursing 2018年第3期5卷 185-191页

作者： Tantut susanto lis Rahmawati Wantiyah Department of Community Family and Geriatric Health Nursing Faculty of Nursing Universitas Jember Jember Jawa Timur 68121 Indonesia Department of Maternity Nursing Faculty of Nursing Universitas Jember Jember Jawa Timur 68121 Indonesia Department of Medical Surgical Nursing Faculty of Nursing Universitas Jember Jember Jawa Timur 68121 Indonesia

Objective： This article aimed to evaluate the effects of an educational intervention programme on improving peer educator （PE） knowledge in issues around growth and development and its risk behavior problems of adolescents in Indonesia. Methods： The study was conducted in 31 of PEs to evaluate their knowledge in adolescents. The PEs received health education and were assessed by individual work during the structured three-week programme. Data were collected before and after the training programme as pre- and post-tests. Results： The PE demonstrated significant improvements in their knowledge after attending the three-week structured training programme. The post-test scores had significant effects on the dimensions of PE knowledge scores. The PE become knowledgeable to maintain and monitor adolescents health issues around growth and development and its risk behavior problems of adolescents. Conclusions： The PE become knowledgeable to respond to the adolescent problems and readiness to become PE during puberty.

关键词： peer educator adolescent development risk behavior assertive

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A community-based friendly health clinic:An initiative adolescent reproductive health project in the rural and urban areas of Indonesia

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International Journal of Nursing Sciences 2016年第4期3卷 371-378页

作者： Tantut susanto Iis Rahmawati Wantiyah Family and Community Health Nursing Department School of NursingUniversity of JemberJl.Kalimantan 37JemberJawa Timur68121Indonesia Maternity Nursing Department School of NursingUniversity of JemberJl.Kalimantan 37JemberJawa Timur68121Indonesia Adult Nursing Depatment School of NursingUniversity of JemberJl.Kalimantan 37JemberJawa Timur68121Indonesia

Objective:This study aims to examine the effects of a community-based friendly health clinic(CFHC)program that adopts manual participatory learning(MPL)intervention on the adolescents living in the rural and urban areas of Indonesia to gain further insights into their knowledge,attitudes,and skills related to adolescent reproductive health(ARH).Methods:A quasi-experimental design was used to obtain information on the ARH knowledge,attitudes,and skills of *** intervention studies that used similar protocols and measures were conducted.A total of 192 adolescents(96 adolescents from urban and rural areas)participated in the project,and the participants from each area were divided into eight groups.A questionairre was adopted to measure the ARH knowledge,attitudes,and skills of these participants.A content analysis of the logbook entries of these respondents was conducted to identify their ARH-related *** questionnairre and self-reported ARH data were collected before and after the eight-week ***:The CFHC program significantly increased the ARH attitudes(p=0.045)and skills(p=0.009)of adolescents in the rural area,but only improved the ARH knowledge(p<0.001)of adolescents in both rural and urban *** themes were identified in three dominant categories,namely,schools,families,and ***:The CFHC with MPL intervention can improve the ARH knowledge,attitudes,and skills of adolescents in the rural area,but can only improve the ARH knowledge of adolescents in the urban *** ARH program must be designed based on the characterictics of these adolescents to improve their life skills during puberty.

关键词： Community-based friendly health clinic Adolescent reproductive health Rural Urban Indonesia

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