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Dendrochronology and climatic signals in the wood of Nectandra oppositifolia from a dense rain forest in southern Brazil

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Journal of Forestry Research 2019年第2期30卷 545-553页

作者： daniela Granato-Souza Eduardo Adenesky-Filho Karin Esemann-Quadros Postgraduate Program in Forestry Regional University of Blumenau-FURB Department of Biological Sciences University of Joinville Region-UNIVILLE

Nectandra is one of the most representative genera of Lauraceae in the subtropical Atlantic Forest of Brazil. The objective of this work was to study the dendrochronological potential of Nectandra oppositifolia Nees and Mart. from two sites in Santa Catarina State in southern Brazil. A tree-ring chronology of 34 trees was developed. The time span ranged from 1843 to 2013. The oldest and youngest trees were 171 and 47 years-old and the average length of the series was 103 years. Average diameter and annual increment were 20.64 cm and0.74 mm a-1; diameter and age were unrelated. The species has good dendrochronological potential with an intercorrelation of 0.61 between sites, indicating the existence of a synchronous pattern in the development of the trees. The climate response of the species could be seen by negative tree growth effects for previous hot and current rainy growth seasons.

关键词： Climate response Dendroclimatology Atlantic forest Growth rings Lauraceae

Leukocyte telomere length and plasma interleukin-1β and interleukin-18 levels in mild cognitive impairment and Alzheimer's disease: new biomarkers for diagnosis and disease progression?

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Neural Regeneration Research 2021年第7期16卷 1397-1398页

作者： Rosa Maria Corbo Rita Businaro daniela Scarabino Department of Biology and Biotechnology Sapienza UniversityRomeItaly Department of Medico-Surgical Sciences and Biotechnologies Sapienza University of RomeLatinaItaly CNR Institute of Molecular Biology and Pathology Rome Italy

Alzheimer's disease and mild cognitive impairment biomarkers: Alzheimer's disease(AD) is a progressive neurodegenerative disease of advancing *** affects around 47 million people in the world and the number is estimated to increase to 152 million by *** develops dementia every three seconds and the current annual cost of dementia is estimated at US $1 trillion, a figure set to double by 2030(Alzheimer's Disease International, 2019).

关键词： Alzheimer impairment diagnosis

Mosaic trisomy 12 diagnosed in a female patient: clinical features, genetic analysis, and review of the literature

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World Journal of Pediatrics 2021年第4期17卷 438-448页

作者： daniela Hainz Marcus Krüger daniela Reber Karl Mehnert Theresa Brunet Gabriele Lederer Sabine Langer-Freitag Julia Hoefele Institute of Human Genetics Klinikum rechts der IsarSchool of MedicineTechnical University of MunichMunichGermany Department of Neonatology Schwabing HospitalSchool of MedicineTechnical University of MunichMunichGermany Genetikum Genetic Counseling and DiagnosticsStuttgartNeu-UlmGermany

Mosaic trisomy 12 is a rare genetic condition with a highly variable *** features associated with this condition include developmental delay,intellectual disability,dysmorphic facial features,short stature,pigmentary dysplasia,complex congenital heart defects and hypotonia(Table 1).To date,20 patients have been described in which mosaic trisomy 12 was observed in both extraembryonic and neonatal/infant tissues.

关键词： Mosaic female Clinical

Sand Liquefaction Phenomena During the Seismic Crisis of May 2012 in Emilia,Northern Italy

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工程科学与技术 2018年第3期50卷 91-94页

作者： LUGLI Stefano FONTANA daniela MARCHETTI DORI Simona FIORONI Chiara BERTOLINI Giovanni Department of Chemical Sciences and Geology University of Modena and Reggio Emilia Modena 441121 Italy Technical Service in the Basins of Tributaries of Po Emilia Romagna Region 42100 Italy

In May 2012,the Emilia region of the Po Valley was struck by a seismic crisis with two major events of magnitude M_w 6.1and M_w *** first event induced widespread sand blows formed along buried channels and old crevasse splay *** the days immediately following the events,the detailed mapping and sampling of the erupted sand was fundamental to record all the seismically-induced *** study of a trench dug across large fractures at San Carlo(Ferrara)provided also valuable information on the sand blows mechanism and *** sedimentological and compositional characteristics of the fracture-filling materials indicate that the sands were erupted from a layer located between 6.8 and 7.5 m *** and deeper Holocene and Pleistocene sand layers were not apparently involved in the liquefaction phenomena.

关键词： sand boils composition Emilia Romagna earthquake

Controlling and regulation of integrated aquaponic production systems – An approach for a management execution system (MES)

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Information Processing in Agriculture 2019年第3期6卷 326-334页

作者： Olaf Witzel Stefan Wilm Divas Karimanzira daniela Baganz Automation&Software Gunther Tausch GmbH Bassower Str.217034 NeubrandenburgGermany Gesellschaft fur Informationsverarbeitung Fertigungssteuerung und Qualita tssicherungIFQ GmbH WismarAlter Holzhafen 17a23966 WismarGermany Department of Surface and Maritime Systems Fraunhofer I0SB-ASTIlmenauAm Vogelherd 5098689 IlmenauGermany Department of Biology and Ecology of Fishes Leibniz-Institute of Freshwater Ecology and Inland FisheriesBerlinGermany

Manufacturing execution systems(MESs)play a significant role in the manufacturing *** is there to link between the Enterprise Resource Planning(ERP)systems and the plant equipment control or Supervisory Control and Data Acquisition(SCADA)*** this paper the MES of the INAPRO aquaponics system which was developed to support and advise the aquaponics managers in operating the complex aquaponic farms,will be *** important feature of the INAPRO aquaponics system is to minimize fresh water<3%,energy and nutrient *** can only be achieved by appropriate design of the fish and crop mixture,considering the fish to crop ratio,when to sow the crops *** to monitor the system to see whether it performing as designed or ***,the MES has a view to show the designed system with all the material flow(water,energy and nutrients)balances and also how the system will be performing for a given predictive *** the future developments of the system,the operator can taking corrective measures to make sure that the system is behaving as *** example of water balance of a system with 40 m3 fish tanks coupled with a hydroponic NFT system with 1,000 m2 which can produce five tons of Tilapia and 75 tons of tomato yearly is given.

关键词： Aquaponics Manufacturing execution system Predictive analytics

Sympathetic activity in breast cancer and metastasis:partners in crime

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Bone Research 2021年第1期9卷 26-36页

作者： Francisco Conceição daniela M.Sousa Joana Paredes Meriem Lamghari I 3S-Instituto de Investigação e Inovação em Saúde Universidade do Porto4200-135 PortoPortugal INEB-Instituto Nacional de Engenharia Biomédica Universidade do Porto4200-135 PortoPortugal ICBAS-Instituto de Ciências Biomédicas Abel Salazar Universidade do Porto4050-313 PortoPortugal IPATIMUP-Instituto de Patologia e Imunologia Molecular da Universidade do Porto 4200-135 PortoPortugal FMUP-Faculdade de Medicina da Universidade do Porto 4200-319 PortoPortugal

The vast majority of patients with advanced breast cancer present skeletal complications that severely compromise their quality of *** cancer cells are characterized by a strong tropism to the bone *** engraftment and colonization of bone,breast cancer cells interact with native bone cells to hinder the normal bone remodeling process and establish an osteolytic“metastatic vicious cycle”.The sympathetic nervous system has emerged in recent years as an important modulator of breast cancer progression and metastasis,potentiating and accelerating the onset of the vicious cycle and leading to extensive bone ***,sympathetic neurotransmitters and their cognate receptors have been shown to promote several hallmarks of breast cancer,such as proliferation,angiogenesis,immune escape,and invasion of the extracellular *** this review,we assembled the current knowledge concerning the complex interactions that take place in the tumor microenvironment,with a special emphasis on sympathetic modulation of breast cancer cells and stromal ***,the differential action of epinephrine and norepinephrine,through eitherα-orβ-adrenergic receptors,on breast cancer progression prompts careful consideration when designing new therapeutic *** addition,the contribution of sympathetic innervation to the formation of bone metastatic foci is *** particular,we address the remarkable ability of adrenergic signaling to condition the native bone remodeling process and modulate the bone vasculature,driving breast cancer cell engraftment in the bone ***,clinical perspectives and developments on the use ofβ-adrenergic receptor inhibitors for breast cancer management and treatment are discussed.

关键词： breast metastasis invasion

Structural evolution and reaction mechanism of lithium nickelate(LiNiO_(2))during the carbonation reaction

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Journal of Materiomics 2018年第1期4卷 56-61页

作者： daniela Gonzalez-Varela Brenda Alcantar-Vazquez Heriberto Pfeiffer Laboratorio de Fisicoquímica y Reactividad de Superficies(LaFReS) Instituto de Investigaciones en MaterialesUniversidad Nacional Autonoma de MexicoCircuito exterior s/nCUDel.CoyoacanCP 04510Ciudad de MexicoMexico Instituto de Ingenieria Coordinacion de Ingeniería AmbientalUniversidad Nacional Autonoma de MexicoCircuito Escolar s/nCUDel.CoyoacanCP 04510Ciudad de MexicoMexico

Lithium nickelate(LiNiO_(2))was synthesized using the lithium excess method,and then characterized by X-ray diffraction,scanning electron microscopy and N_(2) ***,differential thermal and thermogravimetric analyses were performed in CO_(2)presence,at high *** show that LiNiO_(2)is able to react with CO_(2)through a complex structural evolution process,where lithium atoms are released to produce Li_(2)CO_(3),while some nickel atoms are rearranged on different Li_(1-x)Ni_(1+x)O_(2)crystalline ***_(2)-CO_(2)reaction kinetic parameters were determined assuming a first-order reaction,where kinetic constants tended to increase as a function of ***,kinetic constant values did not follow a linear *** atypical behavior was attributed to LiNiO_(2)sintering and crystalline evolution performed as a function of temperature.

关键词： Lithium nickelate CO_(2)chemisorption Lithium diffusion coefficient Phase transition

Anti-TNF alpha in the treatment of ulcerative colitis:A valid approach for organ-sparing or an expensive option to delay surgery?

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World Journal of Gastroenterology 2014年第17期20卷 4839-4845页

作者： Gianluca Rizzo daniela Pugliese Alessandro Armuzzi Claudio Coco Department of Surgical Sciences Complesso Integrato ColumbusCatholic University of the Sacred Heart00168 RomeItaly Internal Medicine and Gastroenterology Unit Complesso Integrato ColumbusCatholic University of the Sacred Heart00168 RomeItaly

Ulcerative colitis (UC) is an inflammatory bowel disease affecting large bowel with variable clinical course. The history of disease has been modified by the introduction of biologic therapy, in particular Infliximab (IFX), that has demonstrated efficacy in inducing fast symptoms remission, promoting mucosal healing and maintaining long-term remission. However, surgery is still needed for UC patients: in case of failure of medical therapy and if acute complications or a malignancy occurred. Surgical treatment is associated with a short-term post-operative mortality and morbidity respectively of 0%-4% and 30%. In this study we systematically analyzed: the role of IFX in reducing the colectomy rate, the risk of post-operative morbidity in pre-operatively IFX-treated patients and the cost-effectiveness of IFX therapy. Four of 5 analyzed randomized controlled trials demonstrated that therapy with IFX significantly reduces the colectomy rate. Moreover, pre-operative treatment with IFX doesn’t seem to increase post-operative infectious complications. By an economic point of view, the cost-effectiveness of IFX-therapy was demonstrated for UC patients suffering from moderate to severe UC in a study based on a cost estimation of the National Health Service of England and Wales. However, the argument is debated.

关键词： Ulcerative colitis Infliximab Colectomy Post-operative complications Cost-effectiveness Inflammatory bowel disease

Esophageal dilations in eosinophilic esophagitis: A single center experience

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World Journal of Gastroenterology 2014年第28期20卷 9549-9555页

作者： Andrew Ukleja Jennifer Shiroky Amitesh Agarwal daniela Allende Department of Gastroenterology Cleveland Clinic Florida the University of Texas Medical Branch at Galveston Cleveland Clinic

AIM: To diagnose the clinical and histologic features that may be associated with or predictive of the need for dilation and dilation related complications; examine the safety of dilation in patients with eosinophilic... 详细信息

关键词： Balloon dilation Dysphagia Esophagus disorder Esophageal stricture Esosinophilic esophagitis