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报告厅钢网架屋盖混合结构受力性能分析

低温建筑技术 2024年第5期46卷 99-102页

作者：卫冕同济大学建筑设计研究院(集团)有限公司上海200092

某报告厅采用钢筋混凝土框架-剪力墙结构+钢网架屋盖的结构形式。为准确对该混合结构进行分析,采用3d3S软件对上部钢网架进行计算,并导入YJK-A软件对下部钢筋混凝土结构进行设计。为保证设计的可靠性,采用MIdASGEN软件建立下部主体结构... 详细信息

某报告厅采用钢筋混凝土框架-剪力墙结构+钢网架屋盖的结构形式。为准确对该混合结构进行分析,采用3d3S软件对上部钢网架进行计算,并导入YJK-A软件对下部钢筋混凝土结构进行设计。为保证设计的可靠性,采用MIdASGEN软件建立下部主体结构+钢网架整体模型进行补充分析,对下部结构和网架的各项指标分别进行对比。结果表明整体模型与独立模型计算结果接近,支座刚度推导及简化方法合理,设计结果可靠。

关键词：钢网架屋盖支座刚度整体分析

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利用惯性传感器与多模态网络解析跑步参数

武汉大学学报（信息科学版） 2024年第7期49卷 1079-1087页

作者：向勉易本顺周丙涛谭建军朱黎湖北民族大学智能科学与工程学院湖北恩施445000 武汉大学电子信息学院湖北武汉430072

实时检测跑步时的速度与步幅在避免运动者受伤、提升运动效率上有着重要意义。提出了一种利用惯性测量单元(inertial measurement unit,IMU)来检测这两个指标的方法。首先,招募了10名志愿者,并将3个IMU模块安置在足部、小腿、大腿处,采... 详细信息

实时检测跑步时的速度与步幅在避免运动者受伤、提升运动效率上有着重要意义。提出了一种利用惯性测量单元(inertial measurement unit,IMU)来检测这两个指标的方法。首先,招募了10名志愿者,并将3个IMU模块安置在足部、小腿、大腿处,采集了5 137个步态周期的数据;然后,利用主成分分析法分析数据,结合皮尔逊相关系数探讨了速度步幅与传感器位置、物理参数之间的关系;提出了一种多模态架构的长短期记忆特征提取网络(multi-modal-attention-long short-term memory,M-Att-LSTM),利用两个引入注意力机制的长短期记忆网络(att-long short-term memory,AttLSTM)对加速度和角度变化分别做特征提取,最后进行回归拟合。实验结果表明,M-Att-LSTM在速度上误差为0.058m/s,标准偏差为0.013 m/s,而在步幅上误差为0.023 m,标准偏差为0.022 m,两项指标都优于单纯的Att-LSTM。

关键词：惯性传感器主成分分析皮尔逊系数长短期记忆网络多模态

Mechanistic insights into the novel glucose-sensitive behavior of P(NIPAM-co-2-AAPBA)

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Science China Chemistry 2020年第3期63卷 377-385页

作者： Qingxian Wang mian Fu Ying Guan Tony d.James Yongjun Zhang Key Laboratory of Functional Polymer Materials and State Key Laboratory of Medicinal Chemical Biology Institute of Polymer ChemistryCollege of ChemistryNankai UniversityTianjin 300071China department of Chemistry University of BathClaverton DownBath BA27AYUK

A glucose-sensitive polymer,poly(N-isopropylacrylamide-co-2-acrylamidophenylboronic acid)(P(NIPAM-co-2-AAPBA)),was synthesized by reversible addition fragmentation chain transfer(RAFT)*** of glucose results in reduced solubility and hence increased turbidity,rather than the normal increase in solubility(decreased turbidity)observed for other PBA-based glucose-sensitive *** novel glucose-sensitive behavior is explained by a new mechanism,in which glucose acts as an additive and depresses the lower critical solution temperature(LCST)of the polymer,instead of increasing solubility by increasing the degree of ionization of the PBA *** and theoretic analysis for the influence of glucose on the thermal behavior of P(NIPAM-co-2-AAPBA)reveals that glucose depresses the LCST of P(NIPAM-co-2-AAPBA)copolymers in a two-stage manner,a fast decrease at low glucose concentrations followed by a slow decrease at high glucose *** low glucose concentrations,the binding of glucose with PBA groups on the polymer chain increases the number of glucose molecules proximal to the polymer which influences the thermal behavior of the polymer,causing a rapid decrease in ***,the transition occurs at a glucose concentration equal to the reciprocal of the binding constant between PBA and glucose,thus providing a novel method to determine the binding *** saccharides,including mannose,galactose and fructose,also depress the LCST of P(NIPAM-co-2-AAPBA)copolymer in the same way.

关键词： glucose-sensitive mechanism phenylboronic acid thermosensitive binding constant lower critical solution temperature polymers

Reduced clinical severity during 2022 Shanghai Spring epidemic of SARS-CoV-2 omicron BA.2 variant infection——an integrated account of virus pathogenicity and vaccination effectiveness

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National Science Review 2024年第4期11卷 24-27页

作者： Xingyue Wu Yao Chen Kangli Cao Yao Shen Xueling Wu Yilin Yang Zhongshu Kuang Qingrun Li Zhenzhen Lu Yichen Jia mian Shao Guorong Gu Xiangwei Wang Ye Yao Ying Wang Shaodie Chen Zhigao Yu Wei Wei Longfei ding Lulu Lan Tianwen Gu Xiangyu Long Jian Sun Lingyu Xing Jiayuan Shen Yi Han Yue Luo Sucheng Mu Mengna Lin Xiaoyan Zhang Rong Zeng Jianqing Xu Guoping Zhao Lihong Huang Zhenju Song department of Emergency Medicine Clinical Center for Bio-Therapy Department of Biostatistics and Department of UrologyShanghai Key Laboratory of Lung Inflammation and Injury Zhongshan Hospital Fudan University department of Respiratory and Critical Care Medicine Shanghai Pudong Hospital Fudan University department of Pulmonology Renji Hospital Shanghai Jiao Tong University School of Medicine Key Laboratory of Systems Biology Center for Excellence in Molecular Cell Science Shanghai Institute of Biochemistry and Cell Biology Chinese Academy of Sciences Shanghai Public Health Clinical Center Fudan University department of Biostatistics School of Public Health Key Laboratory of Public Health Safety of Ministry of Education and Shanghai Institute of Infectious Disease and Biosecurity School of Public Health Fudan University Shanghai Institute of Immunology Department of Immunology and Microbiology Shanghai Institute of Virology Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of EducationSchool of Medicine Shanghai Jiao Tong University State Key Laboratory of Genetic Engineering Fudan Microbiome CenterSchool of Life Sciences Fudan University Bio-Med Big data Center Shanghai Institute of Nutrition and Health Chinese Academy of Sciences

The emergence of SARS-Co V-2 variant of concern omicron BA.2 led to high infection incidence rates as well as reduced severity of COVId-19 during the Shanghai Spring epidemic of 2022 [1]. We assessed the role of viral pathogenicity and the effectiveness of inactivated vaccines in a retrospective observational study including 10 258 confirmed COVId-19cases identified between April and June of 2022, from four COVId-19 designated hospitals located in two areas of Shanghai, namely the West Bund and the East Bund, where the populations’ demographic characteristics varied significantly (Table S1, Fig. S1).

关键词： REPLICATION

肝动脉灌注化疗联合瑞戈非尼治疗结直肠癌肝转移患者的临床研究

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中国临床药理学杂志 2024年第2期40卷 185-189页

作者：彭涛杨沔金梁斌沈雷斌宁波市医疗中心李惠利医院结直肠肛肠外科浙江宁波315000

目的观察肝动脉灌注化疗(HAIC)联合瑞戈非尼治疗结直肠癌肝转移的近远期效果。方法入选结直肠癌肝转移患者作为研究对象,按队列法分为试验组和对照组。对照组采用mFOLFOX6的HAIC化疗方案,试验组在对照组的基础上第1~21 d联合口服瑞戈非... 详细信息

目的观察肝动脉灌注化疗(HAIC)联合瑞戈非尼治疗结直肠癌肝转移的近远期效果。方法入选结直肠癌肝转移患者作为研究对象,按队列法分为试验组和对照组。对照组采用mFOLFOX6的HAIC化疗方案,试验组在对照组的基础上第1~21 d联合口服瑞戈非尼160 mg治疗,28 d为1个周期。治疗28 d后评价近期疗效,比较2组患者肿瘤标志物、肝功能、远期疗效、药物不良反应。结果试验组入组38例和对照组入组42例。试验组和对照组的客观缓解率分别为26.32%和9.52%,疾病控制率分别为71.05%和47.62%,治疗后,试验组和对照组的血清癌胚抗原水平分别为(10.06±2.33)和(14.67±3.50)μg·L^(-1),糖类抗原199水平分别为(41.39±10.25)和(62.19±15.38)kU·L^(-1),糖类抗原242水平分别为(8.67±2.12)和(13.04±3.17)kU·L^(-1),血清糖类抗原125水平分别为(36.52±9.18)和(45.22±9.01)kU·L^(-1),血清谷草转氨酶水平分别为(26.44±6.72)和(33.17±8.20)U·L^(-1),谷丙转氨酶水平分别为(22.98±5.78)和(30.89±7.62)U·L^(-1),中位无进展生存期分别为3.7和2.7个月,中位总生存期分别为11.7和9.4个月。试验组上述指标与对照组比较,在统计学上差异均有统计学意义(均P0.05)。结论HAIC联合瑞戈非尼治疗结直肠癌肝转移显著提高近期疗效,延长患者生存期,临床获益较好。

关键词：瑞戈非尼肝动脉灌注化疗结直肠癌肝转移疗效肿瘤标志物

Malignant glaucoma treated by low-dose laser cycloplasty: a 1-year multicenter prospective noncomparative study

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International Journal of Ophthalmology(English edition) 2024年第7期17卷 1248-1254页

作者： Hai-Shuang Lin Xiao-Ping Xu Xuan-Li Zheng Ji-Bing Wang Su-Jie Fan Zuo-HongWu Su-mian Cheng Li-Jun Zhao Qin-Hua Cai Shao-dan Zhang Shan-Shan Liu Ai-Guo Lyu Ying Zhang Hong Chen dan-Ni Jiang Wu-Liang Li Nathan Congdon Clement C Tham Ming-Guang He Yuan-Bo Liang the Malignant Glaucoma TreatmentTrial Study(MGTT)Group Wenzhou Medical University Wenzhou 325027Zhejiang ProvinceChina Ningbo Eye Hospital Ningbo 315100Zhejiang ProvinceChina Weifang Eye Hospital Weifang 261000Shandong ProvinceChina Handan Eye Hospital Handan 056000Hebei ProvinceChina Aier Eye Hospital(Wuhan) Wuhan 430061Hubei ProvinceChina Hebei Eye Hospital Xingtai 054001Hebei ProvinceChina The Third People’s Hospital of dalian Dalian 116033Liaoning ProvinceChina First Affiliated Hospital of Suzhou University Suzhou 215031Jiangsu ProvinceChina National Clinical Research Center for Ocular diseases Eye HospitalWenzhou Medical UniversityWenzhou 325027Zhejiang ProvinceChina Glaucoma Research Institute Wenzhou Medical UniversityWenzhou 325027Zhejiang ProvinceChina Centre for Public Health Queen’s University BelfastBelfast BT71NNUK Orbis International New YorkUSA department of Ophthalmology and Visual Sciences the Chinese University of Hong KongHong Kong SAR 999077China Centre for Eye Research Australia University of MelbourneRoyal Victorian Eye and Ear HospitalEast Melbourne 3000VICAustralia 不详

AIM:To report a one-year clinical outcomes of low-dose laser cycloplasty(LCP)among malignant glaucoma ***:In this prospective,multicenter,noncomparative clinical study,participants with malignant glaucoma were recruited and underwent LCP at eight ophthalmic centers in *** were followed up at 1wk,1,3,6,and *** pressure(IOP),number of glaucoma medications,anterior chamber depth(ACd),and complications were *** success was defined as the reformation of the anterior chamber based on slit-lamp *** was defined by the presence of a shallow orﬂat anterior chamber after initial recovery from ***:A total of 34 eyes received *** IOP and medications decreased from 36.1±11.5 mm Hg with 3.3±1.5 glaucoma medications pre-treatment to 20.9±9.8 mm Hg(Pdications(P=0.046)at 1d,and 17.4±6.7 mm Hg(Pdications(Pd increased from 1.1±0.8 mm at baseline to 1.7±1.0 mm and to 2.0±0.5 mm at 1d and 12mo,respectively.A total of 32(94.1%)eyes achieved initial anatomical *** follow-up,2(5.9%)eyes failed and 8(23.5%)eyes relapsed,yielding a 12-month anatomical success rate of 64.3%.Complications including anterior synechia(8.82%),choroidal/ciliary detachment(5.88%)and hypopyon(2.94%)were observed within ***:LCP is simple,safe,and effective in reforming the anterior chamber in malignant glaucoma.

关键词： anterior chamber reformation intraocular pressure low-dose laser cycloplasty malignant glaucoma anatomical success

贝索夫空间中三维布辛涅斯克方程的一些新的正则性准则

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Chinese Quarterly Journal of Mathematics 2024年第1期39卷 73-81页

作者：邹绵璐李强 School of Big data and Artificial Intelligence Xinyang CollegeXinyang 464000China School of Mathematics and Statistics Xinyang CollegeXinyang 464000China

In this paper, we study the regularity criterion for the three-dimensional Boussinesq equations in Besov spaces. We show that the smooth solution(u,θ) is regular if the horizonal velocity u_h holds ■.

关键词： Boussinesq equations Velocity components Regularity criterion

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摩托车后驱动链条声改善初探

小型内燃机与车辆技术 2024年第2期53卷 93-96页

作者：钱勉朱冬文江门市大长江集团有限公司豪爵研发中心广东江门329000

针对采用滚子链进行驱动的摩托车后驱动系统中链轮与链条之间产生的啮合机械声进行了系统的分析。首先通过多体动力学仿真的方式解析了该声音的冲击过程。利用此多体动力学模型探讨了发动机小链轮齿形设计参数对声音的影响并通过试验方... 详细信息

针对采用滚子链进行驱动的摩托车后驱动系统中链轮与链条之间产生的啮合机械声进行了系统的分析。首先通过多体动力学仿真的方式解析了该声音的冲击过程。利用此多体动力学模型探讨了发动机小链轮齿形设计参数对声音的影响并通过试验方式进行验证。特别地,针对含缓冲橡胶形式的发动机小链轮与链条之间的啮合噪声进行了分析。阐述了随行驶里程的增加,链条声恶化程度与缓冲橡胶磨损量之间的关系。建立了发动机小链轮缓冲橡胶面压分析的静力学模型,并提出了改善发动机小链轮缓冲橡胶面压的具体方案,从而减小后驱动链条声。

关键词：链条声机械声发动机小链轮面压缓冲橡胶

3d-STI参数评价抗HER-2药物对乳腺癌患者心室功能变化的价值

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中国医疗设备 2024年第3期39卷 129-133,145页

作者：勉丽张茜王霞新疆医科大学第二附属医院超声科新疆乌鲁木齐830000

目的探讨三维斑点追踪成像(Three dimensional Speckle Tracking Imaging,3d-STI)参数评价抗人表皮生长因子受体-2(Human Epidermal Growth Factor Receptor-2,HER-2)药物对乳腺癌患者心室功能变化的价值。方法选取我院2021年6月至2022年6月收治的50例需行辅助化疗乳腺癌患者作为观察组,选择同期30名健康志愿者作为对照组。比较对照组与观察组化疗前,化疗第2、4、6周期常规超声心动图指标与3d-STI参数,以临床病理诊断为“金标准”,并绘制3d-STI参数受试者工作特征(Receiver Operating Characteristic,ROC)曲线。结果观察组化疗第6周期E/A值低于对照组和化疗前(PdinalStrain,GLS)低于对照组和化疗前(Pd-STI参数可评估乳腺癌患者抗HER-2药物化疗后心室功能变化,为临床早期干预提供诊断依据。

关键词：乳腺癌人表皮生长因子受体-2 三维斑点追踪成像心室功能