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绵羊心脏的X射线影像研究

现代畜牧科技 2024年第3期 8-11页

作者：袁歆玮黄文任涛张梦迪何娅贺建忠塔里木大学动物科学学院新疆阿拉尔843300

为描述麻醉后健康绵羊心脏形态大小的基本数据指标,该试验通过对8只健康绵羊进行全身麻醉,分别用X线机在吸气结束时拍摄绵羊的左侧位、右侧位、背腹位、腹背位的胸部X光片。运用传统的测量评估法和椎体测量系统对心脏的形态大小的基本... 详细信息

为描述麻醉后健康绵羊心脏形态大小的基本数据指标,该试验通过对8只健康绵羊进行全身麻醉,分别用X线机在吸气结束时拍摄绵羊的左侧位、右侧位、背腹位、腹背位的胸部X光片。运用传统的测量评估法和椎体测量系统对心脏的形态大小的基本数据指标进行评估,建立参考范围。结果表明,麻醉后对绵羊胸腔内的心脏测量心胸比率(LH+RH)/LAT范围为0.65±0.16,椎体心脏比分(VHS)范围为(8.25±3.66)v,气管分叉处背侧胸椎椎体长度(Tn)范围为(37.81±2.02)mm,心基部到胸椎距离(Br-Sp)范围是(54.79±2.80)mm,胸深(d)范围是(214.25±6.19)mm,后腔静脉宽度(CVC)的范围(18.74±0.72)mm。上述结果对绵羊胸部疾病诊断有很大作用。

关键词：心脏绵羊 X射线

2022年底新型冠状病毒奥密克戎变异株流行期新生儿感染的临床特征

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中华医院感染学杂志 2024年第1期34卷 112-115页

作者：陈玲傅晓春林雅茵曹佳莉林雪燕吴佳音叶辉铭厦门大学附属妇女儿童医院(厦门市妇幼保健院)医学检验科福建省临床重点专科医学检验学科福建厦门361003 厦门大学附属妇女儿童医院(厦门市妇幼保健院)新生儿科福建厦门361003 厦门大学附属妇女儿童医院(厦门市妇幼保健院)产科福建厦门361003 厦门大学公共卫生学院福建厦门361102

目的分析2022年底新型冠状病毒奥密克戎变异株流行期新生儿感染的临床特征,为临床新生儿新型冠状病毒感染处置提供参考。方法选取2022年12月17日-2023年1月9日厦门大学附属妇女儿童医院收治的新型冠状病毒奥密克戎变异株感染新生儿为研... 详细信息

目的分析2022年底新型冠状病毒奥密克戎变异株流行期新生儿感染的临床特征,为临床新生儿新型冠状病毒感染处置提供参考。方法选取2022年12月17日-2023年1月9日厦门大学附属妇女儿童医院收治的新型冠状病毒奥密克戎变异株感染新生儿为研究对象,回顾性分析新生儿感染病例的实验室检查结果及临床特征。结果共纳入100例新型冠状病毒感染患儿,年龄为17.5(8.3,22.0)日龄,出生胎龄39.3(38.4,40.1)周,出生体质量3165(2991,3522)g;100例患儿中轻型84例,15例普通型,1例重型;患儿均有明确接触史,大部分为水平传播获得感染;临床表现以发热为主(91.0%),间断发热2.5(1.5,3.0)d;40例(40.0%)合并呼吸系统症状,23例(23.0%)有消化系统症状;实验室检测WBC计数未见明显升高,C-反应蛋白(CRP)、降钙素原(PCT)绝大部分在正常范围内;患儿年龄、体温与住院时间均呈负相关(P<0.05),发热时间与住院时间呈正相关(P<0.05),但相关关系均不密切;出生体质量、胎龄和最初病毒载量均与住院时间不相关。结论新生儿新型冠状病毒感染以轻型居多,临床症状以发热为主,对症支持治疗后总体预后良好。出生体质量、胎龄和核酸Ct值均与住院时间不相关。

关键词：新生儿新型冠状病毒感染奥密克戎变异株BA.5.2 奥密克戎变异株BF.7 临床症状

褐煤添加对羊粪有机肥发酵过程中水溶性有机物光谱学变化特征的影响

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光谱学与光谱分析 2019年第11期39卷 3579-3584页

作者：董利超王晓霞马力通王亚雄内蒙古科技大学化学与化工学院内蒙古包头014010 生物煤化工综合利用内蒙古自治区工程研究中心内蒙古包头014010 内蒙古自治区煤化工与煤炭综合利用重点实验室内蒙古包头014010

研究添加褐煤对羊粪有机肥中水溶性有机物(dOM)光谱学特性的影响,为高腐殖酸有机肥的腐熟度评价提供依据。以内蒙古褐煤、羊粪为原料,添加10%褐煤进行羊粪有机肥发酵,对不同阶段有机肥样品的dOM进行紫外可见光谱、荧光光谱、FtiR的表征... 详细信息

研究添加褐煤对羊粪有机肥中水溶性有机物(dOM)光谱学特性的影响,为高腐殖酸有机肥的腐熟度评价提供依据。以内蒙古褐煤、羊粪为原料,添加10%褐煤进行羊粪有机肥发酵,对不同阶段有机肥样品的dOM进行紫外可见光谱、荧光光谱、FtiR的表征。紫外-可见吸收光谱分析显示,有机肥样品的E4/E6值随着有机肥发酵的进行呈现出先下降后上升的趋势,由有机肥开始时的9.110 4降至最低为4.647 7,再升为有机肥结束时的5.390 1;A1呈现先减小后增大趋势,A2和A3均呈现先增大后减少的趋势,峰值出现在12d。同步荧光光谱显示,荧光峰光强的比值(i470/i435)由有机肥起始的0.452 8上升至有机肥结束的0.655 2;AHLR/AFLR呈现上升趋势,从有机肥开始的0.673 9上升至有机肥结束的1.040 8。经过18d的有机肥发酵后,有机肥发酵结束后样品荧光强度小于有机肥起始时的荧光强度,而且10%褐煤添加的羊粪有机肥的相对荧光强度明显高于未添加褐煤的荧光强度。FtiR显示,18d的有机肥发酵过程中dOM中的碳水化合物、蛋白质被逐渐分解,而羧基、含苯环的物质含量明显增加。随着发酵的进行,dOM中的非腐殖质物质转化为类腐殖质,不饱和结构的多聚化或联合程度变大,稳定度增加;添加褐煤可以有效促进羊粪中木质素类物质的分解,提高羊粪有机肥dOM的芳构化程度,促进羊粪有机肥腐熟。

关键词：羊粪褐煤有机肥水溶性有机物光谱学特性

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三角形周期荷载作用下软基路堤沉降研究

岩土力学 2010年第11期31卷 3411-3416页

作者：胡亚元浙江大学岩土工程研究所杭州310027 浙江大学软弱土与环境土工教育部重点实验室杭州310027

采用能够同时考虑主次固结变形的Yin-Graham一维弹黏塑性模型,对三角形周期荷载作用下软土路堤运行期间和运行期结束时的长期沉降进行了理论分析,获得三角形周期荷载作用下软基路堤运行期结束时的总沉降计算公式和工后沉降计算公式。分... 详细信息

采用能够同时考虑主次固结变形的Yin-Graham一维弹黏塑性模型,对三角形周期荷载作用下软土路堤运行期间和运行期结束时的长期沉降进行了理论分析,获得三角形周期荷载作用下软基路堤运行期结束时的总沉降计算公式和工后沉降计算公式。分析了三角形周期荷载作用下软基不考虑流固耦合与考虑流固耦合时长期沉降之间的相互关系,证明了三角形周期荷载作用下当循环荷载次数趋向于无穷大时软基具有最终沉降量与应力随时间增长的模式无关的性质。按照文中提供的总沉降计算公式,针对具体工程的土工参数,对路堤运行期结束时的总沉降量进行了计算,并由此确定运行期开始时软基应发生的沉降量,为合理确定高速公路路面铺筑时机提供沉降标准。

关键词：路堤沉降三角形周期荷载主次固结弹粘塑性模型

Multi-Classification of Polyps in Colonoscopy images Based on an improved deep Convolutional Neural Network

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Computers, materials & Continua 2023年第6期75卷 5837-5852页

作者： Shuang Liu Xiao Liu Shilong Chang Yufeng Sun kaiyuan Li ya Hou Shiwei Wang Jie Meng Qingliang Zhao Sibei Wu kun yang Linyan Xue College of Quality and Technical Supervision Hebei UniversityBaoding071002China Hebei Technology innovation Center for Lightweight of New Energy Vehicle Power System Baoding071002China National&Local Joint Engineering Research Center of Metrology instrument and System Hebei UniversityBaoding071002China College of Electronic information Engineering Hebei UniversityBaoding071002China department of Orthopedics Affiliated Hospital of Hebei UniversityBaoding071002China State key Laboratory of Molecular Vaccinology and Molecular diagnostics Center for Molecular Imaging and Translational MedicineDepartment of Laboratory MedicineSchool of Public HealthXiamen UniversityXiamen361102China

Achieving accurate classification of colorectal polyps during colonoscopy can avoid unnecessary endoscopic biopsy or *** study aimed to develop a deep learning model that can automatically classify colorectal polyps histologically on white-light and narrow-band imaging(NBi)colonoscopy images based on World Health Organization(WHO)and Workgroup serrAted polypS and Polyposis(WASP)classification criteria for colorectal ***-light and NBi colonoscopy images of colorectal polyps exhibiting pathological results were firstly collected and classified into four categories:conventional adenoma,hyperplastic polyp,sessile serrated adenoma/polyp(SSAP)and normal,among which conventional adenoma could be further divided into three sub-categories of tubular adenoma,villous adenoma and villioustublar adenoma,subsequently the images were re-classified into six *** this paper,we proposed a novel convolutional neural network termed Polyp-dedNet for the four-and six-category classification tasks of colorectal *** on the existing classification network ResNet50,Polyp-dedNet adopted dilated convolution to retain more high-dimensional spatial information and an Efficient Channel Attention(ECA)module to improve the classification performance *** eliminate gridding artifacts caused by dilated convolutions,traditional convolutional layers were used instead of the max pooling layer,and two convolutional layers with progressively decreasing dilation were added at the end of the *** to the inevitable imbalance of medical image data,a regularization method dropBlock and a Class-Balanced(CB)Loss were performed to prevent network ***,the 5-fold cross-validation was adopted to estimate the performance of Polyp-dedNet for the multi-classification task of colorectal *** accuracies of the proposed Polyp-dedNet for the four-and six-category classifications of colorectal polyps were 89.91%±0.92%and 85.13%±1.10%,respectively.

关键词： Colorectal polyps four-and six-category classifications convolutional neural network dilated residual network

Selective brain hypothermia-induced neuroprotection against focal cerebral ischemia/reperfusion injury is associated with Fis1 inhibition

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Neural Regeneration Research 2020年第5期15卷 903-911页

作者： ya-Nan Tang Gao-Feng Zhang Huai-Long Chen Xiao-Peng Sun Wei-Wei Qin Fei Shi Li-Xin Sun Xiao-Na Xu Ming-Shan Wang department of Anesthesiology Affiliated Qingdao Municipal Hospital of Qingdao UniversityQingdaoShandong ProvinceChina department of Central Laboratory Affiliated Qingdao Municipal Hospital of Qingdao UniversityQingdaoShandong ProvinceChina

Selective brain hypothermia is considered an effective treatment for neuronal injury after stroke,and avoids the complications of general ***,the mechanisms by which selective brain hypothermia affects mitochondrial fission remain *** this study,we investigated the effect of selective brain hypothermia on the expression of fission 1 (Fis1) protein,a key factor in the mitochondrial fission system,during focal cerebral ischemia/reperfusion ***-dawley rats were divided into four *** the sham group,the carotid arteries were exposed *** the other three groups,middle cerebral artery occlusion was performed using the intraluminal filament *** 2 hours of occlusion,the filament was slowly removed to allow blood reperfusion in the ischemia/reperfusion ***,at 4℃ and 37℃,were perfused through the carotid artery in the hypothermia and normothermia groups,respectively,followed by restoration of blood *** function was assessed with the Zea Longa 5-point scoring *** infarct volume was assessed by 2,3,5-triphenyltetrazolium chloride staining,and apoptosis was assessed by terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling ***1 and cytosolic cytochrome c levels were assessed by western blot ***1 mRNA expression was assessed by quantitative reverse transcription-polymerase chain *** ultrastructure was evaluated by transmission electron *** with the sham group,apoptosis,Fis1 protein and mRNA expression and cytosolic cytochrome c levels in the cortical ischemic penumbra and cerebral infarct volume were increased after reperfusion in the other three *** changes caused by cerebral ischemia/reperfusion were inhibited in the hypothermia group compared with the normothermia *** findings show that selective brain hypothermia inhibits Fis1 expression and reduces apoptosis,thereby ameliorating focal cerebral ischemia/repe

关键词： apoptosis Fis1 hypothermia ischemia/reperfusion injury mitochondria mitochondrial fission mitochondrial ultrastructure neuroprotection selective brain hypothermia stroke

Sonographic features of umbilical vein recanalization for a Rex shunt on cavernous transformation of portal vein in children

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World Journal of Clinical Cases 2020年第22期8卷 5555-5563页

作者： Yu-Qing Zhang Qing Wang Mei Wu ya Li Xiu-Liang Wei Fei-Xue Zhang yan Li Guang-Rui Shao Juan Xiao department of Ultrasound The Second HospitalCheeloo College of MedicineShandong UniversityJinan 250033Shandong ProvinceChina department of Radiology Qilu HospitalCheeloo College of MedicineShandong UniversityJinan 250012Shandong ProvinceChina department of Nuclear Medicine The Second HospitalCheeloo College of MedicineShandong UniversityJinan 250033Shandong ProvinceChina department of Radiology The Second HospitalCheeloo College of MedicineShandong UniversityJinan 250033Shandong ProvinceChina Center of Evidence-Based Medicine Institute of Medical SciencesThe Second HospitalCheeloo College of MedicineShandong UniversityJinan 250033Shandong ProvinceChina

BACkGROUNd The Rex shunt was widely used as the preferred surgical approach for cavernous transformation of the portal vein(CTPV)in children that creates a bypass between the superior mesenteric vein and the intrahepatic left portal vein(LPV).This procedure can relieve portal hypertension and restore physiological hepatopetal ***,the modified procedure is technically demanding because it is difficult to make an end-to-end anastomosis of a bypass to a hypoplastic *** studies reported using a recanalized umbilical vein as a conduit to resolve this ***,the feasibility of umbilical vein recanalization for a Rex shunt has not been fully *** To investigate the efficacy of a recanalized umbilical vein as a conduit for a Rex shunt on CTPV in children by *** A total of 47 children who were diagnosed with CTPV with prehepatic portal hypertension in the Second Hospital,Cheeloo College of Medicine,Shandong University,were enrolled in this *** children received a recanalized umbilical vein as a conduit for a Rex shunt surgery and were enrolled in group ***-two children received the classic Rex shunt surgery and were enrolled in group *** sonographic features of the two groups related to intraoperative and postoperative variation in terms of bypass vessel and the LPV were *** The patency rate of group i(60.0%,9/15)was significantly lower than that of group ii(87.5%,28/32)7 d after(on the 8th d)operation(Pinical anticoagulation treatment for 3 mo,there was no significant difference in the patency rate between group i(86.7%,13/15)and group ii(90.6%,29/32)(P>0.05).Moreover,3 mo after(at the beginning of the 4th mo)surgery,the inner diameter significantly widened and flow velocity notably increased for the bypass vessels and the sagittal part of the LPV compared to intraoperative values in both shunt groups(Pignificant difference between the two surgic

关键词： Cavernous transformation of the portal vein Rex shunt Recanalization Umbilical vein Ultrasonography

Evaluation of high-risk factors and the diagnostic value of alpha-fetoprotein in the stratification of primary liver cancer

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World Journal of Clinical Cases 2022年第26期10卷 9264-9275页

作者： Hong-Bin Jiao Wei Wang Meng-Nan Guo ya-Li Su de-Quan Pang Bao-Lin Wang Jun Shi Jing-Hua Wu Clinical Laboratory Tangshan Maternal and Child Health Care HospitalNorth China University of Science and TechnologyTangshan 063000Hebei ProvinceChina department of Oncology Tangshan Maternal and Child Health Care HospitalNorth China University of Science and TechnologyTangshan 063000Hebei ProvinceChina Clinical Laboratory Tangshan Nanhu HospitalTangshan 063000Hebei ProvinceChina

BACkGROUNd Alpha-fetoprotein(AFP)is one of the diagnostic standards for primary liver cancer(PLC);however,AFP exhibits insufficient sensitivity and specificity for diagnosing *** To evaluate the effects of high-risk factors and the diagnostic value of AFP in stratified *** in total,289 PLC cases from 2013 to 2019 were selected for ***,the contributions of high-risk factors in stratifying PLC were compared according to the following criteria:Child–Pugh score,clinical stage of liver cirrhosis,tumor size,and Barcelona Clinic Liver Cancer(BCLC)***,the diagnostic value of AFP was evaluated in different stratifications of PLC by receiver operating characteristic *** PLC cases in which AFP played little role,the diagnostic values of carcinoembryonic antigen(CEA),carbohydrate antigen 19-9(CA 19-9),gamma-glutamyl transferase(GGT),and AFP were *** The roles of high-risk factors differed in stratified *** incidence of smoking and drinking history was higher in PLC with Child–Pugh scores of C(Ptitis B virus(HBV)infection rate in PLC with cirrhosis was more than in PLC without cirrhosis(Pmall tumors were more prone to cirrhosis than large tumors(Pd PLC was more likely to be associated with HBV infection and cirrhosis(Pigher in PLC with cirrhosis,diffuse tumors,and BCLC stage d *** diagnosing PLC defined as Child–Pugh A,B,and C,massive hepatoma,diffuse hepatoma,BCLC stage B,C,and d,and AFP showed significant diagnostic value[all area under the curve(AUC)>0.700].However,these measures were meaningless(AUCin small hepatomas and BCLC A stage PLC,but could be replaced by the combined detection of CEA,CA 19-9,GGT,and AFP(AUC=0.810 and 0.846,respectively).CONCLUSiON Stratification of PLC was essential for precise diagnoses and benefited from evaluating AFP levels.

关键词： Primary liver cancer Stratification Risk factors Alpha-fetoprotein Receiver operating characteristic curve diagnostics

电针对高脂血症合并脑缺血损伤大鼠海马区钙结合蛋白d28k蛋白表达的影响

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针刺研究 2010年第1期35卷 22-26页

作者：马惠芳任秀君图娅周蕾北京中医药大学针灸学院北京100029 北京中医药大学期刊中心北京100029

目的:观察针刺对高脂血症合并脑缺血损伤大鼠大脑海马区细胞凋亡及钙结合蛋白(Calbindin)d28 k(CB)表达的影响。方法:Sd雄性大鼠,随机分为正常对照组、模型组、治疗Ⅰ组和治疗Ⅱ组,每组10只。采用经典高脂配方饲料喂养并结合FeCl3化学... 详细信息

目的:观察针刺对高脂血症合并脑缺血损伤大鼠大脑海马区细胞凋亡及钙结合蛋白(Calbindin)d28 k(CB)表达的影响。方法:Sd雄性大鼠,随机分为正常对照组、模型组、治疗Ⅰ组和治疗Ⅱ组,每组10只。采用经典高脂配方饲料喂养并结合FeCl3化学刺激诱导血栓性闭塞大脑中动脉,造成大鼠高脂血症合并脑缺血模型。其中治疗Ⅰ组先电针"三阴交""丰隆",每日1次,治疗10 d后再造脑缺血模型;治疗Ⅱ组在造模成功后再开始治疗。两治疗组造模完成后均电针"三阴交""丰隆",手针"百会""水沟",每日1次,治疗7 d。应用免疫组化方法观察大鼠海马区CB蛋白表达的变化,原位末端标记染色法观察海马区神经细胞的凋亡情况。结果:高脂血症大鼠局灶性脑缺血后细胞凋亡率较正常组明显增高,CB阳性细胞较正常组明显减少,阳性强度也减弱(P<0.05);针刺后各治疗组CB阳性细胞的表达明显增加,其中治疗Ⅰ组较治疗Ⅱ组增加显著(P<0.05),同时各治疗组神经细胞凋亡亦明显减少,以治疗Ⅰ组较为明显(P<0.05)。结论:针刺可减少高脂血症大鼠海马区神经细胞的凋亡,增加CB的表达,减轻脑缺血损伤程度。

关键词：高脂血症合并脑缺血电针 CB表达海马CA 3区