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家庭血压远程监测与社区卫生工作者相结合改善血压(LINK-BP)项目的设计与原理

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中华高血压杂志(中英文) 2023年第12期31卷 1284-1284页

作者： Commodore-Mensah Y Liu X Ogungbe O Ibe C Amihere J Mensa M Martin SS Crews D Carson KA cooper la Himmelfarb CR 刘青练桂丽

在美国,非洲裔和西班牙裔成人以及生活贫困的人高血压结局的差异仍然存在。家庭血压远程监测与社区卫生工作者相结合改善血压(linked with com-munity health workers to improve blood pressure,LINK-BP)项目是一个多层次的干预项目,...

在美国,非洲裔和西班牙裔成人以及生活贫困的人高血压结局的差异仍然存在。家庭血压远程监测与社区卫生工作者相结合改善血压(linked with com-munity health workers to improve blood pressure,LINK-BP)项目是一个多层次的干预项目,将家庭血压监测与移动健康应用程序、社区卫生工作者的支持以及初级保健实践中的血压测量培训相结合,

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Multiple color patches and parasites in Sceloporus occidentalis:differential relationships by sex and infection

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Current Zoology 2018年第6期64卷 703-711页

作者： Rodrigo MEGIA-PALMA Dhanashree PARANJPE Senda REGUERA Javier MARTINEZ Robert D cooper Pauline BlaIMONT Santiago MERINO Barry SINERVO Department of Ecologia Evolutiva Museo Nacional de Ciencias Naturales-CSICJose Gutierrez Abascal 2.Madrid E-28006Spain Departrnent of Ecology and Evolutionary Biology University of CaliforniaSanta Cruz1156High StSanta CruzCA 95064USA Department of Zoologia Facultad de CienciasUniversidad de GranadaGranada E-18071Spain Area Parasitologia Department of Biomedicina y BiotecnologiaArea de ParasitologiaFacultad de FarmaciaUniversidad de Alcala de HenaresAlcala de HenaresMadrid E-28871Spain

Parasites generally have a negative influence on the color expression of their *** selection theory predicts resistant high-quality individuals should show intense coloration,whereas susceptible low-quality individuals would show poor ***,intensely colored males of different species of Oid and New World lizards were more often infected by *** results suggest that high-quality males,with intense coloration,would suffer higher susceptibility to *** hypothesis remains poorly understood and contradicts general theories on sexual *** surveyed a population of Sceloporus occidentalis for parasites and found infections by the parasite genera lankesterella and *** this population,both males and females express ventral blue and yellow color *** was almost exclusively infecting *** body size of the males significantly predicted the coloration of both blue and yellow *** males showed darker (lower lightness)blue ventral patches and more saturated yellow patches that were also ***,these males were more often infected by lankesterella than smaller *** intestinal parasite Acroeimeria infected both males and *** infection by intestinal parasites of the genus Acroeimeria was the best predictor for the chroma in the blue patch of the males and for hue in the yellow patch of the *** males infected by Acroeimeria expressed blue patches with significantly lower chroma than the uninfected ***,the hue of the yellow patch was not significantly different between infected and uninfected *** results suggest a different effect of lankesterella and Acroeimeria on the *** the one hand,the intense coloration of male lizards infected by lankesterella suggested high-quality male lizards may tolerate *** the other hand,the low chroma of the blue coloration of the infected males suggested that this coloration could honest

关键词： animal communication coloration Hamilton and Zuk parasites sexual selection

Regionalization of epididymal duct and epithelium in rats and mice by automatic computer-aided morphometric analysis

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Asian Journal of Andrology 2005年第3期7卷 267-275,页

作者： C.Soler J.J.deMonserrat M.Núez R.Gutiérrez J.Núez M.Sancho T.G.cooper Departmentof Functional Biology and Physical Anthropology University of ValènciaValència 46112Spain Departamentode Ouímica y Biología Universidad del NorteBarranquillaColombia Instituteof Reproductive Medicine University of MünsterMünster D-48129Germany

Aim： To establish a rat and mouse epididymal map based on the use of the Epiquatre automatic software for histologic image analysis. Methods： Epididymides from five adult rats and five adult mice were fixed in alcoholic Bouin＇s fixative and embedded in paraffin. Serial longitudinal sections through the medial aspect of the organ were cut at 10 jam and stained with hematoxylin and eosin. As determined from major connective tissue septa, nine subdivisions of the rat epididymis and seven for the mouse were determined, consisting of five sub-regions in the caput （rat and mouse）, one （mouse） or three （rat） in the corpus and one in the cauda （rat and mouse）. Using the Epiquatre software, several tubular, luminal and epithelial morphometric parameters were evaluated. Results： Statistical comparison of the quantitative parameters revealed regional differences （2-5 in the rat, 3-6 in the mouse, dependent on parameters） with caput regions 1 and 2 being largely distinguishable from the similar remaining caput and corpus, which were in turn recognizable from the cauda regions in both species. Conclusion： The use of the Epiquatre software allowed us to establish regression curves for different morphometric parameters that can permit the detection of changes in their values under different pathological or experimental conditions. （Asian J Androl 2005 Sep; 7： 267-275）

关键词： rat mouse epididymis morphometry zonation computer-aided image analysis Epiquatre Software

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Factors associated with change in frailty scores and long-term outcomes in older adults with coronary artery disease

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Journal of Geriatric Cardiology 2021年第3期18卷 196-203页

作者： S.Michael Gharacholou Joshua P.Slusser Ryan J.Lennon Carolyn R.Flock Leslie T.cooper Patricia A.Pellikka Jorge Brenes Salazar Mandeep Singh Department of Cardiovascular Medicine Mayo ClinicJacksonvilleFLUSA Department of Cardiology Mayo Health SystemLa CrosseWIUSA Department of Biostatistics Mayo ClinicRochesterMNUSA Department of Cardiovascular Medicine Mayo ClinicRochesterMNUSA

OBJECTIVE Older adults with coronary artery disease(CAD)are at risk for ***,little is known regarding transition in frailty measures over time or its impact on *** sought to determine the association of temporal change in frailty with long-term outcome in older adults with *** We re-assessed for phenotypic frailty using the Fried index(0=not frail;1−2=pre-frail;≥3 frail)in a cohort of CAD patients≥65 years old at 2 time points 5 years *** associated with frailty worsening were assessed with scatterplots and outcomes estimated using the Kaplan-Meier *** models were used to assess the risk of worsening frailty on *** There were 45 subjects that completed both baseline and 5-year Fried frailty *** age was 74.6±5.9 and 30(67%)were *** incidence increased over time:baseline(3%frail,37%pre-frail);5 years(10%frail,40%pre-frail).Baseline factors were not predictors of worsening frailty score,while both slower walk time(r=0.46;P=0.004)and diminishing grip strength(r=−0.39;P=0.01)were associated with worsening frailty *** follow-up(median 5.2 years),long-term major adverse cardiac event(MACE)free survival(P=0.12)or hospitalization(P=0.98)was not different for those with worsening frailty score(referent:improved/unchanged frailty).Frailty worsening had a trend towards increased risk of MACE(HR=1.86;95%CI:0.65−5.27,P=0.25).CONCLUSIONS Frailty transitions,specifically,declines in walk time and grip strength,were strongly associated with worsening frailty score in a cohort of older adults with CAD than were baseline indices,though frailty change status was not independently associated with MACE outcomes.

关键词： coronary unchanged score

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西班牙人为什么10点才吃晚饭

复印报刊资料（当代文萃） 2017年第11期 44-45页

作者： cooper 不详

许多去西班牙旅游的人都认为,西班牙吃晚饭的时间正反映了这个国家的人民悠闲的生活态度,然而事实并非如此。现在是晚上10点,在马德里最古老的街区la latina,鹅卵石街道边的餐厅忙碌热闹,人们正在享用大蒜虾和马德里肉汤。同样是这个时... 详细信息

许多去西班牙旅游的人都认为,西班牙吃晚饭的时间正反映了这个国家的人民悠闲的生活态度,然而事实并非如此。现在是晚上10点,在马德里最古老的街区la latina,鹅卵石街道边的餐厅忙碌热闹,人们正在享用大蒜虾和马德里肉汤。同样是这个时间,很多国家的厨师们都已经脱下围裙准备下班了。

关键词：西班牙人马德里悠闲生活态度

脑血管损害对主动脉僵硬度与记忆相关性的影响

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中华高血压杂志 2015年第10期23卷 951-951页

作者：刘莉叶鹏 cooper LL Woodard T Sigurdsson S van Buchem MA Torjesen AA Inker la Aspelund T Eiriksdottir G Harris TB Gudnason V launer LJ Mitchell GF

主动脉僵硬度与认知功能降低有关。该文探索颈股动脉脉搏波传导速度（carorid—femoralpulsewavevelocity，cfPWV）与认知功能的关系，确定是否脑血管重塑和实质小血管病变损害对该相关性有影响。方法：纳入年龄、基因／环境敏感Reykja... 详细信息

主动脉僵硬度与认知功能降低有关。该文探索颈股动脉脉搏波传导速度（carorid—femoralpulsewavevelocity，cfPWV）与认知功能的关系，确定是否脑血管重塑和实质小血管病变损害对该相关性有影响。方法：纳入年龄、基因／环境敏感Reykjavik研究中的1820名（60％为女性）受试者作为研究对象。

关键词：主动脉僵硬度脑血管损害相关性脉搏波传导速度记忆认知功能小血管病变血管重塑

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冠心病患者钙拮抗剂与非钙拮抗剂降压治疗策略：国际维拉帕米与群多普利随机对照试验

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美国医学会杂志（中文版） 2005年第3期24卷 131-137页

作者： CarlJ.Pepine EileenM.Handberg RhondaM.cooper-DeHoff RonaldG.Marks PeterKowey FranzH.Messerli GiuseppeMancia JoséLCangiano DavidGarcia-Barreto MatyasKeltai SerapErdine HeatherA.Bristol H.RobertKolb GeorgeL.Bakris JeromeD.Cohen WilliamW.Parmley 陈江天徐成斌 DivisionofCardiovascularMedicine DepartmentsofMedicineUniversityofFloridaCollegeofMedicineGainesville DepartmentofMedicine UniversityofCaliforniaSanFrancisco DivisionofCardiovascularMedicine DepartmentsofStatisticsUniversityofFloridaCollegeofMedicineGainesville DepartmentofPreventiveMedicine RushUniversityChicagoIII DivisionofCardiovascularMedicine DepartmentsofMedicineUniversityofFloridaCollegeofMedicineGainesville 不详 DepartmentofMedicine LankenauHospitalWynnewoodPa DepartmentofMedicine UniversitaDegtiStudiMonzaItaly DepartmentofMedicine OchsnerClinicNewOrleansLa InstitutodeCardiologiayCirugiaCardiovascular HavanaCuba DepartmentofCardiology SemmelweisUniversityBudapestHungary ClinicalasAmericas HatReyPuertoRico CardiologyInstitute UniversityofIstanbulIstanbulTurkey DepartmentofMedicine SaintLouisUniversityStLouisMo

背景：尽管有证据显示，降压治疗对高血压患者有效，但是其对冠心病(coronary artery disease，CAD)的安全性及疗效的数据仅见于大型试验的亚组分析。目的：在采用钙拈抗剂治疗方案(calcium antagonist strategy，CAS)或非钙拮抗剂治疗... 详细信息

背景：尽管有证据显示，降压治疗对高血压患者有效，但是其对冠心病(coronary artery disease，CAD)的安全性及疗效的数据仅见于大型试验的亚组分析。目的：在采用钙拈抗剂治疗方案(calcium antagonist strategy，CAS)或非钙拮抗剂治疗方案(non-calcium antagonist strategy，NCAS)的高血压CAD患者中进行比较。设计、地点和参试者：随机、开标(open-label)、盲法终点研究。研究于1997年9月至2003年2月在14个国家的862家单位的22576例高血压CAD患者中进行。患者年龄≥50岁。干预：患者随机接受CAS(盐酸维拉帕米缓释剂)或NCAS(阿替洛尔)。两种治疗均有详细的剂量及用药方案。高血压预防、检查、评估和治疗全国联合委员会第7次报告(JNC ⅥI)指出，如果患者存在糖尿病或肾损伤，收缩压应lative risk，RR]，0．98；95％可信区间[confidence interval[CI]，0．90～1．06]。两组两年内血压控制情况相似。CAS组达到JNCⅦ目标血压者分别为65．0％(收缩压)和88．5％(舒张压)，NCAS组为64．0％(收缩压)和88．1％(舒张压)。CAS组总共有71．7％而NCAS有70．7％的患者达到收缩压<140mmHg、舒张压<90mmHg的水平。结论：对高血压CAD患者而言，以维拉帕米+群多普利为基础的治疗方案与以阿替洛尔+双氢克尿塞为基础的方案一样有效。

关键词：群多普利钙拮抗剂随机对照试验冠心病患者治疗策略维拉帕米缓释剂双氢克尿塞血压控制情况 disease 2003年2月全国联合委员会致死性心肌梗死治疗方案国际 artery AD患者阿替洛尔目标血压高血压患者 1997年

Performance and calibration of quark/gluon-jet taggers using 140 fb^(-1) of pp collisions at √s=13 TeV with the ATlaS detector

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Chinese Physics C 2024年第2期48卷 1-25页

作者： G. Aad B. Abbott K. Abeling N.J. Abicht S.H. Abidi A. Aboulhorma H. Abramowicz H. Abreu Y. Abulaiti B.S. Acharya C. Adam Bourdarios L. Adamczyk S.V. Addepalli M.J. Addison J. Adelman A. Adiguzel T. Adye A.A. Affolder Y. Afik M.N. Agaras J. Agarwala A. Aggarwal C. Agheorghiesei A. Ahmad F. Ahmadov W.S. Ahmed S. Ahuja X. Ai G. Aielli A. Aikot M. Ait Tamlihat B. Aitbenchikh I. Aizenberg M. Akbiyik T.P.A. Åkesson A.V. Akimov D. Akiyama N.N. Akolkar K. Al Khoury G.L. Alberghi J. Albert P. Albicocco G.L. Albouy S. Alderweireldt M. Aleksa I.N. Aleksandrov C. Alexa T. Alexopoulos F. Alfonsi M. Algren M. Alhroob B. Ali H.M.J. Ali S. Ali S.W. Alibocus M. Aliev G. Alimonti W. Alkakhi C. Allaire B.M.M. Allbrooke J.F. Allen C.A. Allendes Flores P.P. Allport A. Aloisio F. Alonso C. Alpigiani M. Alvarez Estevez A. Alvarez Fernandez M. Alves Cardoso M.G. Alviggi M. Aly Y. Amaral Coutinho A. Ambler C. Amelung M. Amerl C.G. Ames D. Amidei S.P. Amor Dos Santos K.R. Amos V. Ananiev C. Anastopoulos T. Andeen J.K. Anders S.Y. Andrean A. Andreazza S. Angelidakis A. Angerami A.V. Anisenkov A. Annovi C. Antel M.T. Anthony E. Antipov M. Antonelli F. Anulli M. Aoki T. Aoki J.A. Aparisi Pozo M.A. Aparo L. Aperio Bella C. Appelt A. Apyan N. Aranzabal S.J. Arbiol Val C. Arcangeletti A.T.H. Arce E. Arena J-F. Arguin S. Argyropoulos J.-H. Arling O. Arnaez H. Arnold G. Artoni H. Asada K. Asai S. Asai N.A. Asbah J. Assahsah K. Assamagan R. Astalos S. Atashi R.J. Atkin M. Atkinson H. Atmani P.A. Atmasiddha K. Augsten S. Auricchio A.D. Auriol V.A. Austrup G. Avolio K. Axiotis G. Azuelos D. Babal H. Bachacou K. Bachas A. Bachiu F. Backman A. Badea P. Bagnaia M. Bahmani A.J. Bailey V.R. Bailey J.T. Baines L. Baines O.K. Baker E. Bakos D. Bakshi Gupta V. Balakrishnan R. Balasubramanian E.M. Baldin P. Balek E. Ballabene F. Balli L.M. Baltes W.K. Balunas J. Balz E. Banas M. Bandieramonte A. Bandyopadhyay S. Bansal L. Barak M. Barakat E.L. Barberio D. Barberis M. Barbero M.Z. Barel K.N. Barends T. Barillari M-S. Barisits T. Barklow P. Baron D.A. Baron Mo The ATlaS Collaboration

The identification of jets originating from quarks and gluons,often referred to as quark/gluon tagging,plays an important role in various analyses performed at the large Hadron Collider,as Standard Model measurements and searches for new particles decaying to quarks often rely on suppressing a large gluon-induced *** paper describes the measurement of the efficiencies of quark/gluon taggers developed within the ATlaS Collaboration,using √s=13 TeV proton–proton collision data with an integrated luminosity of 140 fb^(-1) collected by the ATlaS *** taggers with high performances in rejecting jets from gluon over jets from quarks are studied:one tagger is based on requirements on the number of inner-detector tracks associated with the jet,and the other combines several jet substructure observables using a boosted decision tree.A method is established to determine the quark/gluon fraction in data,by using quark/gluon-enriched subsamples defined by the jet *** in tagging efficiency between data and simulation are provided for jets with transverse momentum between 500 GeV and 2 TeV and for multiple tagger working points.

关键词： ATlaS JET QUARK GLUON TAGGING