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Aerobic vs anaerobic exercise training effects on the cardiovascular system

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World Journal of Cardiology 2017年第2期9卷 134-138页

作者： Harsh Patel Hassan Alkhawam Raef Madanieh Niel Shah constantine e kosmas Timothy J Vittorio Department of Internal Medicine State University of New York at Brooklyn-School of Medicine Department of Medicine Icahn School of Medicine at Mount Sinai(Elmhurst) St.Francis Hospital-the Heart Center^® Center for Advanced Cardiac Therapeutics Icahn School of Medicine Mount Sinai Hospital Center

Physical exercise is one of the most effective methods to help prevent cardiovascular(CV) disease and to promote CV health. Aerobic and anaerobic exercises are two types of exercise that differ based on the intensity, interval and types of muscle fibers incorporated. In this article, we aim to further elaborate on these two categories of physical exercise and to help decipher which provides the most effective means of promoting CV health.

关键词： Cardiovascular exercise Training Aerobic Anaerobic

Cardiovascular Benefits of Testosterone Replacement Therapy in the Andropausal Male

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Health 2015年第9期7卷 1206-1214页

作者： Satya K. Vatti Raef Madanieh Abed Madanieh constantine e. kosmas Timothy J. Vittorio St. Francis Hospital—The Heart Center&reg Division of Cardiology Center for Advanced Cardiac Therapeutics Roslyn NY USA Zena and Michael A Wiener Cardiovascular Institute Icahn School of Medicine at Mount Sinai New York USA

Androgen deficiency has been receiving a lot of attention as an evolving health concern in the in-dustrialized world. With population aging, hypogonadism has become a challenging medical problem confronting practicing physicians. The importance of this increasingly prevalent disease arises from its potentially debilitating and serious consequences, such as atherosclerosis, diabetes mellitus, metabolic disorders, muscular weakness, psychiatric illness, sexual dysfunction and vascular inflammation. When left untreated, testosterone deficiency is associated with increased cardiovascular mortality.

关键词： Cardiovascular Hormones Hypogonadism Testosterone Therapy

Bile duct ligation in rats: A reliable model of hepatorenal syndrome?

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World Journal of Gastroenterology 2009年第1期15卷 121-123页

作者： Stelios F Assimakopoulos constantine e Vagianos Department of Internal Medicine University Hospital of PatrasPatras 26504 Greece First Surgical Department "Saint Panteleimon" General Hospital of NikaiaPiraeus 18454Greece

The two most widely used experimental models of advanced liver disease are the administration of carbon tetrachloride, and common bile duct ligation (BDL), however, neither has been systematically evaluated as a model of hepatorenal syndrome (HRS). The BDL model in rats, studied at diverse time points, induced a progressive renal dysfunction without structural changes in the kidney. The authors concluded that BDL is a good model for further studies of HRS and its treatment. However, the renal impairment observed at the acute phase of the BDL model is based on a different pathophysiology than that of HRS. Specifi cally, in acute obstructive jaundice, cholemia predominates over parenchymal liver disease (reversible at this stage without portal hypertension or cirrhosis) and independently induces negative inotropic and chronotropic effects on the heart, impaired sympathetic vasoconstriction response and profound natriuresis and diuresis that might lead to volume depletion. In addition, systemic endotoxemia contributes to the prerenal etiology of renal impairment and promotes direct nephrotoxicity and acute tubular necrosis. On the other hand, the renal failure observed in the chronic BDL model (with development of biliary cirrhosis, portal hypertension and ascites) shares pathophysiological similarities with HRS, but the accordance of the chronic BDL model to the diagnostic criteria of HRS (e.g. absence of spontaneous bacterial peritonitis, no renal function improvement after plasma volume expansion) should have been confirmed. In conclusion, we think that the BDL model is not suitable for the study of the natural history of HRS, but the chronic BDL model might be valid for the study of established HRS and its potential therapies.

关键词：肝肾综合征胆管结扎实验模型大鼠模型肝硬化门静脉高压症自发性细菌性腹膜炎急性梗阻性黄疸急性肾小管坏死

Influence of an external DC electric Current on Plasma Cleaning Rate: an Application on the enlarged Plasma-Surface Theor

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Plasma Science and Technology 2013年第5期15卷 448-454页

作者： constantine L. XAPLANTeRIS eleni D. FILIPPAKI Plasma Physics Lab IMS NCSR "Demokritos" Hellenic Military Academy

During the last decades many researchers have been occupied with other plasma applications apart from the big challenge which the thermonuclear fusion poses. Many experiments have been carried out on the plasma behavior in contact with a solid surface; when the surface material consists of chemical compounds （e.g. oxides of metals）, then the plasma chemistry takes place. The present paper contains the final experimental and theoretical work of Plasma Laboratory at ＂Demokritos＂, which consists of an elaboration of plasma sheath parameters adapted to experimental conditions, a suitable choice of plasma gases （either H 2 or N 2 ）, and an electric po-tential current enforcement on objects. Additionally, a brief theory is given to explain the results, with a short reference to both boundary phenomena in thermonuclear reactors and low pressure plasma of glow discharges, so as to reveal the similarities and differences of these two cases. An extensive examination of the treated objects by X-ray diffraction method （XRD） gives results in agreement with the theoretical predictions. Using this improvement on plasma restoration system, （a combination of electric current on metallic object into suitable plasma）, it is shown that better results can be achieved on the cleaning and conservation of archaeological objects.

关键词： impurities plasma sheath parameters reduction of surfaces external poten-tial treatment rate

STRONG SHOCKS IN NONISeNTROPIC GAS DYNAMICS

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Acta Mathematica Scientia 2009年第4期29卷 973-979页

作者： constantine M. Dafermos Division of Applied Mathematics Brown University

In nonisentropic gas dynamics, with general equations of state, strong cornpressive shocks satisfying the Liu e-condition may violate the Second Law of thermodynamics.

关键词： gas dynamics entropy Lax e-condition Liu e-condition

Antenna Theory: Analysis and Design, 3rd edition 3

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Unilateral leg edema in a cirrhotic patient with tense ascites

2005年

作者： constantine A. Balanis

本书内容有导论,电路原理图设计的基本方法和技巧,电路系统设计的基本步骤,印刷电路板设计流程,印刷电路板设计的技巧和后处理方法,层次电路电路图设计的思想,层次电路原理图的设计和使用方法,元件库的创建和修改方法,两个}杂的设计实... 详细信息

ISBN: (纸本)9780471667827;047166782X

本书内容有导论,电路原理图设计的基本方法和技巧,电路系统设计的基本步骤,印刷电路板设计流程,印刷电路板设计的技巧和后处理方法,层次电路电路图设计的思想,层次电路原理图的设计和使用方法,元件库的创建和修改方法,两个}杂的设计实例等。

关键词： Antennas (electronics)

来源：畅想之星图书光盘版（南... 评论

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World Journal of Gastroenterology 2006年第35期12卷 5746-5747页

作者： Stelios F Assimakopoulos Konstantinos C Thomopoulos Christine Kalogeropoulou Ioannis Maroulis Alexandra Lekkou Christos Papakonstantinou constantine e Vagianos Charalambos Gogos Department of Internal Mcdicine School of MedieineUniversity of PatrasPatrasgreece Department of Radiology School of MedicineUniversity of Patraspatrasgreece Department of surgery School of MedicineUniversity of palrasPatrasGreece

TO THe eDITORA 61 year old man with cirrhosis and hepatocellular carcinoma developed on the background of chronic hepatitis B was admitted because of acute and gradually intensified right thigh pain and swelling, which, within a few hours, was expanded to his right foot. The patient,due to ascites refractory to diuretics, was almost weekly subjected to large volume paracentesis of ascitic fluid for the last six months; meanwhile he has developed a left inguinal, a right femoral and an umbilical hernia. It should be noted that 48 h before admission, the patient was referred to the emergency room because of dyspnoea and 5 L of ascitic fluid were removed.

关键词：水肿肝硬化腹水治疗

Pathophysiology of increased intestinal permeability in obstructive jaundice

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World Journal of Gastroenterology 2007年第48期13卷 6458-6464页

作者： Stelios F Assimakopoulos Chrisoula D Scopa constantine e Vagianos Department of Internal Medicine School of Medicine University of Patras Department of Pathology School of Medicine University of Patras 1~(st) Surgical Department "Saint Panteleimon" General Hospital of Nikaia

Despite advances in preoperative evaluation and postoperative care, intervention, especially surgery, for relief of obstructive jaundice still carries high morbidity and mortality rates, mainly due to sepsis and renal dysfunction. The key event in the pathophysiology of obstructive jaundice-associated complications is endotoxemia of gut origin because of intestinal barrier failure. This breakage of the gut barrier in obstructive jaundice is multi-factorial, involving disruption of the immunologic, biological and mechanical barrier. experimental and clinical studies have shown that obstructive jaundice results in increased intestinal permeability. The mechanisms implicated in this phenomenon remain unresolved, but growing research interest during the last decade has shed light in our knowledge in the field. This review summarizes the current concepts in the pathophysiology of obstructive jaundice-induced gut barrier dysfunction, analyzing pivotal factors, such as altered intestinal tight junctions expression, oxidative stress and imbalance of enterocyte proliferation and apoptosis. Clinicians handling patients with obstructive jaundice should not neglect protecting the intestinal barrier function before, during and after intervention for the relief of this condition, which may improve their patients’ outcome.

关键词：阻塞性黄疸渗透性细菌感染肠疾病

Beneficial effect of an antibody against interleukin-2 receptor (daclizumab) in an experimental model of hepatocyte xenotransplantation

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World Journal of Gastroenterology 2007年第9期13卷 1435-1437页

作者： Dimitrios Papagoras Apostolos Papalois Alexandra Tsaroucha Dimitrios Lytras John Kyriazanos Nikoletta Giannakou Prodromos Laftsidis constantine Simopoulos 2~(nd) Department of Surgery Medical School "Democritus" University of Thrace AlexandroupolisGreece 2~(nd) Department of Surgery Medical School "Democritus" University of Thrace AlexandroupolisGreeceExperimental-Research Department Elpen Pharmaceuticals Athens Greece Department of Pathology "Aghia Olga" General Hospital AthensGreece

AIM: To investigate the use of Daclizumab (Dmab) as an immunosuppressive agent in an experimental model of hepatocyte xenotransplantation (XenoTx) in rats with fulminant hepatic failure (FHF). MeTHODS: Two white male New Zealand rabbits were used as donors and 68 Wistar rats as recipients. FHF was induced by intravenous application of dimethylnitrosamine (DMNA). The isolated hepatocytes of the rabbits were xenotransplanted into the spleen of the rats 24 h after FHF induction. Group A (n = 13): no treatment; Group B (n = 14): FHF and XenoTx; Group C (n = 14): FHF and XenoTx and cyclosporin (CsA); Group D (n = 14): FHF and XenoTx and Dmab; Group e (n = 13): FHF and XenoTx and CsA and Dmab. The rats were followed for 15 d. ReSULTS: Statistical analysis showed better survival among groups D (92.86%) and e (76.92%) compared to group A (all rats died after 72 h), group B (28.57%) or group C (71.43%), although the differences were not statistically significant. Biochemical evaluation of the liver enzymes and histology confirmed satisfactory function and engraftment, respectively. CONCLUSION: This experimental model has shown the safe, effective and beneficial use of Dmab in a xenotransplantation model of rabbit hepatocytes in rats.

关键词：肝细胞移植异种移植实验模型抗体白介素-2受体